mitotane has been researched along with Feminization in 8 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Feminization: Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report here a new case of feminizing adrenocortical carcinoma revealed by a bilateral gynecomastia in a 50 year old man." | 1.29 | [Bilateral gynecomastia revealing malignant feminizing adrenocortical carcinoma]. ( Chraibi, A; Kadiri, A, 1994) |
| "Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization." | 1.25 | [Corticosuprarenaloma in children]. ( Benaily, M; Job, JC; Schweisguth, O, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katsumata, N | 1 |
| Kadiri, A | 1 |
| Chraibi, A | 1 |
| Benaily, M | 1 |
| Schweisguth, O | 1 |
| Job, JC | 1 |
| Boyar, RM | 1 |
| Nogeire, C | 1 |
| Fukushima, D | 1 |
| Hellman, L | 1 |
| Fishman, J | 1 |
| deAsis, DN | 1 |
| Samaan, NA | 1 |
| Fang, VS | 1 |
| Freeman, DA | 1 |
| Harrison, JH | 1 |
| Mahoney, EM | 1 |
| Bennett, AH | 1 |
2 reviews available for mitotane and Feminization
| Article | Year |
|---|---|
[Feminizing adrenocortical tumor].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Combined Modality Therapy; Diagnosis, Diffe | 2006 |
Steroid hormone-producing tumors in man.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androgens; C | 1986 |
6 other studies available for mitotane and Feminization
| Article | Year |
|---|---|
[Bilateral gynecomastia revealing malignant feminizing adrenocortical carcinoma].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Diagnosis, Differential; Feminization; Gynecomas | 1994 |
[Corticosuprarenaloma in children].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal G | 1975 |
Studies of the diurnal pattern of plasma corticosteroids and gonadotropins in two cases of feminizing adrenal carcinoma: measurements of estrogen and corticosteroid production.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Androgens; Circad | 1977 |
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult | 1978 |
Cytotoxic activity of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (mitotane) and its analogs on feminizing adrenal neoplastic cells in culture.
Topics: Adrenal Gland Neoplasms; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Estrogens; Femi | 1979 |
Proceedings: Tumors of the adrenal cortex.
Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortico | 1973 |