Page last updated: 2024-10-31

mitotane and Ectopic Hormone Syndromes

mitotane has been researched along with Ectopic Hormone Syndromes in 13 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Research Excerpts

ExcerptRelevanceReference
"Amelioration of the hypercortisolism occurred after removal of the bronchial adenoma."1.25Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis. ( Bruderman, I; Griffel, WB; Gutman, A; Myers, B; Shapiro, MS, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brauckhoff, M1
Dralle, H1
Courvoisier, B1
Lobel, H1
Rudnicki, K1
Zahavi, I1
Solomon, CG1
Dluhy, RG2
Kawai, S1
Ichikawa, Y1
Kaburaki, J1
Yoshida, T1
Kishi, DT1
deAsis, DN1
Samaan, NA1
Shapiro, MS1
Gutman, A1
Bruderman, I1
Myers, B1
Griffel, WB1
Eriksson, B1
Oberg, K1
Curstedt, T1
Hemmingsson, A1
Johansson, H1
Lindh, E1
Lindgren, PG1
Thuomas, KA1
Wilander, E1
Akerström, G1
Freeman, DA1
Sparagana, M1
Ackerman, L1
Harrison, JH1
Mahoney, EM1
Bennett, AH2
Newmark, SR1

Reviews

3 reviews available for mitotane and Ectopic Hormone Syndromes

ArticleYear
[Recurrent operations on the adrenal glands].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2005, Volume: 76, Issue:3

    Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Anti

2005
Current therapeutic concepts--Cushing's syndrome.
    Journal of the American Pharmaceutical Association, 1975, Volume: 15, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Ci

1975
Steroid hormone-producing tumors in man.
    Endocrine reviews, 1986, Volume: 7, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androgens; C

1986

Other Studies

10 other studies available for mitotane and Ectopic Hormone Syndromes

ArticleYear
[Clinical reports: pseudohypoparathyroidism, pituitary nanism, and adrenal carcinoma].
    Schweizerische medizinische Wochenschrift. Supplementum, 1982, Volume: 13

    Topics: 17-Hydroxycorticosteroids; Acne Vulgaris; Adrenal Gland Neoplasms; Adult; Androgens; Dihydrotachyste

1982
[Adrenal cortical carcinoma].
    Harefuah, 1982, Volume: 103, Issue:3-4

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Female; Humans; Mitotane; Neoplasm Recurre

1982
Paraneoplastic endocrine syndromes.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndr

1994
18 years mitotane therapy for intractable Cushing's disease.
    Lancet (London, England), 1999, Sep-11, Volume: 354, Issue:9182

    Topics: Adult; Antineoplastic Agents, Hormonal; Cushing Syndrome; Female; Follow-Up Studies; Humans; Long-Te

1999
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
    Archives of internal medicine, 1978, Volume: 138, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult

1978
Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis.
    Israel journal of medical sciences, 1975, Volume: 11, Issue:9

    Topics: Adenoma; Adrenalectomy; Adult; Aminoglutethimide; Bronchial Neoplasms; Cushing Syndrome; Dexamethaso

1975
Treatment of hormone-producing adrenocortical cancer with o,p'DDD and streptozocin.
    Cancer, 1987, Apr-15, Volume: 59, Issue:8

    Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Cort

1987
Positive iodine-131 6 beta-iodomethyl-19-norcholesterol (NP-59) adrenal images can precede return of adrenocortical function after o,p' DDD treatment.
    Clinical nuclear medicine, 1988, Volume: 13, Issue:5

    Topics: 19-Iodocholesterol; ACTH Syndrome, Ectopic; Adrenal Glands; Adult; Cholesterol; Humans; Iodine Radio

1988
Proceedings: Tumors of the adrenal cortex.
    Cancer, 1973, Volume: 32, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortico

1973
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
    Urology, 1973, Volume: 2, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco

1973