mitotane has been researched along with Diabetes Mellitus in 9 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In untreated hyperadrenocorticism, clinical problems may result from metastasis of an adrenocortical carcinoma, growth of a pituitary tumor, or complications associated with sustained hypercortisolemia itself, such as hypertension, cardiovascular disease, thromboembolism, glucose intolerance, and increased susceptibility to infection." | 2.40 | Complications and concurrent disease associated with canine hyperadrenocorticism. ( Nichols, R, 1997) |
| " After successful initial treatment metabolic control deteriorated although insulin dosage was increased." | 1.30 | [Case presentation in small animal medicine]. ( Gfeller, G; Reusch, C, 1998) |
| " By lowering the dosage of o,p'-DDD and supplementing with glucocorticoids during the o,p'-DDD loading period, serious hypoglycemia was avoided." | 1.26 | Diagnosis and management of concurrent diabetes mellitus and hyperadrenocorticism in thirty dogs. ( Nesbitt, GH; Peterson, ME; Schaer, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, ME | 3 |
| Nesbitt, GH | 1 |
| Schaer, M | 1 |
| Nichols, R | 2 |
| Kintzer, PP | 1 |
| Schwedes, CS | 1 |
| Gfeller, G | 1 |
| Reusch, C | 1 |
| Ling, GV | 1 |
| Lowenstine, LJ | 1 |
| Pulley, LT | 1 |
| Kaneko, JJ | 1 |
| Zerbe, CA | 1 |
| Nachreiner, RF | 1 |
| Dunstan, RW | 1 |
| Dalley, JB | 1 |
3 reviews available for mitotane and Diabetes Mellitus
| Article | Year |
|---|---|
Concurrent illness and complications associated with canine hyperadrenocorticism.
Topics: Acute Disease; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; D | 1994 |
Medical treatment of pituitary-dependent hyperadrenocorticism. Mitotane.
Topics: Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents, Hormonal; Dia | 1997 |
Complications and concurrent disease associated with canine hyperadrenocorticism.
Topics: Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Diabetes Comp | 1997 |
6 other studies available for mitotane and Diabetes Mellitus
| Article | Year |
|---|---|
o,p'-DDD (mitotane) treatment of canine pituitary-dependent hyperadrenocorticism.
Topics: Adrenocorticotropic Hormone; Animals; Cortisone; Cushing Syndrome; Diabetes Complications; Diabetes | 1983 |
Diagnosis and management of concurrent diabetes mellitus and hyperadrenocorticism in thirty dogs.
Topics: Animals; Cushing Syndrome; Diabetes Mellitus; Dog Diseases; Dogs; Female; Insulin; Male; Mitotane | 1981 |
Mitotane (o,p'-DDD) treatment in a cat with hyperadrenocorticism.
Topics: Adrenal Cortex; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents, Hormonal; Blood Glucos | 1997 |
[Case presentation in small animal medicine].
Topics: Animals; Antineoplastic Agents, Hormonal; Cushing Syndrome; Diabetes Complications; Diabetes Mellitu | 1998 |
Diabetes mellitus in dogs: a review of initial evaluation, immediate and long-term management, and outcome.
Topics: Amylases; Animals; Anorexia; Bicarbonates; Blood Glucose; Blood Urea Nitrogen; Cushing Syndrome; Deh | 1977 |
Hyperadrenocorticism in a cat.
Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Animals; Cat Diseases; Cats; Cushing Syndrome; Diabet | 1987 |