mitotane has been researched along with Complications of Diabetes Mellitus in 7 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In untreated hyperadrenocorticism, clinical problems may result from metastasis of an adrenocortical carcinoma, growth of a pituitary tumor, or complications associated with sustained hypercortisolemia itself, such as hypertension, cardiovascular disease, thromboembolism, glucose intolerance, and increased susceptibility to infection." | 2.40 | Complications and concurrent disease associated with canine hyperadrenocorticism. ( Nichols, R, 1997) |
| " After successful initial treatment metabolic control deteriorated although insulin dosage was increased." | 1.30 | [Case presentation in small animal medicine]. ( Gfeller, G; Reusch, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mukoyama, M | 1 |
| Nakao, K | 1 |
| Peterson, ME | 2 |
| Nichols, R | 2 |
| Kintzer, PP | 1 |
| Gfeller, G | 1 |
| Reusch, C | 1 |
| Zerbe, CA | 1 |
| Nachreiner, RF | 1 |
| Dunstan, RW | 1 |
| Dalley, JB | 1 |
4 reviews available for mitotane and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[Selective hypoaldosteronism].
Topics: Cytochrome P-450 CYP11B2; Diabetes Complications; Diagnosis, Differential; Humans; Hyperkalemia; Hyp | 2006 |
Concurrent illness and complications associated with canine hyperadrenocorticism.
Topics: Acute Disease; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; D | 1994 |
Medical treatment of pituitary-dependent hyperadrenocorticism. Mitotane.
Topics: Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents, Hormonal; Dia | 1997 |
Complications and concurrent disease associated with canine hyperadrenocorticism.
Topics: Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Diabetes Comp | 1997 |
3 other studies available for mitotane and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
o,p'-DDD (mitotane) treatment of canine pituitary-dependent hyperadrenocorticism.
Topics: Adrenocorticotropic Hormone; Animals; Cortisone; Cushing Syndrome; Diabetes Complications; Diabetes | 1983 |
[Case presentation in small animal medicine].
Topics: Animals; Antineoplastic Agents, Hormonal; Cushing Syndrome; Diabetes Complications; Diabetes Mellitu | 1998 |
Hyperadrenocorticism in a cat.
Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Animals; Cat Diseases; Cats; Cushing Syndrome; Diabet | 1987 |