mitotane has been researched along with Complication, Postoperative in 4 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "UA induced remission of hypercortisolism in all patients, with sustained significant clinical improvement." | 1.42 | Unilateral Adrenalectomy as a First-Line Treatment of Cushing's Syndrome in Patients With Primary Bilateral Macronodular Adrenal Hyperplasia. ( Benoit, M; Caron, P; Chabre, O; Chaffanjon, P; Debillon, E; Lambert, B; Massoutier, M; Salenave, S; Tabarin, A; Velayoudom-Cephise, FL; Wagner, T; Young, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, AR | 1 |
| Hammer, GD | 1 |
| Else, T | 1 |
| Debillon, E | 1 |
| Velayoudom-Cephise, FL | 1 |
| Salenave, S | 1 |
| Caron, P | 1 |
| Chaffanjon, P | 1 |
| Wagner, T | 1 |
| Massoutier, M | 1 |
| Lambert, B | 1 |
| Benoit, M | 1 |
| Young, J | 1 |
| Tabarin, A | 1 |
| Chabre, O | 1 |
| Raux-Demay, MC | 1 |
| Girard, F | 1 |
| Godil, MA | 1 |
| Atlas, MP | 1 |
| Parker, RI | 1 |
| Priebe, CJ | 1 |
| Zerah, MM | 1 |
| Kane, P | 1 |
| Tsung, J | 1 |
| Wilson, TA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism[NCT05255900] | 20 participants (Anticipated) | Observational | 2022-04-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitotane and Complication, Postoperative
| Article | Year |
|---|---|
[Cushing syndrome in children].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hor | 1993 |
3 other studies available for mitotane and Complication, Postoperative
| Article | Year |
|---|---|
Transcutaneous biopsy of adrenocortical carcinoma is rarely helpful in diagnosis, potentially harmful, but does not affect patient outcome.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents; | 2014 |
Unilateral Adrenalectomy as a First-Line Treatment of Cushing's Syndrome in Patients With Primary Bilateral Macronodular Adrenal Hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenalectomy; Adrenocorticotropic Hormone; | 2015 |
Metastatic congenital adrenocortical carcinoma: a case report with tumor remission at 3 1/2 years.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Follow-Up Stud | 2000 |