mitotane has been researched along with Chronic Disease in 3 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitotane proved to be an efficacious drug which in exceptional cases can be used without significant side effects in low dosage for the long-term treatment of hypothalamic-pituitary Cushing disease." | 5.30 | [The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)]. ( Gerl, H; Knappe, G; Rohde, W; Ventz, M, 1997) |
| "Mitotane proved to be an efficacious drug which in exceptional cases can be used without significant side effects in low dosage for the long-term treatment of hypothalamic-pituitary Cushing disease." | 1.30 | [The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)]. ( Gerl, H; Knappe, G; Rohde, W; Ventz, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shuayb, M | 1 |
| Das, A | 1 |
| Uddin, MN | 1 |
| Knappe, G | 1 |
| Gerl, H | 1 |
| Ventz, M | 1 |
| Rohde, W | 1 |
| Vasiukova, EA | 1 |
| Pisarskaia, IV | 1 |
3 other studies available for mitotane and Chronic Disease
| Article | Year |
|---|---|
Long-term survival in recurrent adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Adult; Antineoplastic Combined C | 2019 |
[The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)].
Topics: Adult; Chronic Disease; Combined Modality Therapy; Cushing Syndrome; Drug Evaluation; Female; Humans | 1997 |
[Change in blood coagulation in Itsenko-Cushing's disease under the influence of chloditan treatment].
Topics: Adult; Blood Coagulation; Chronic Disease; Cushing Syndrome; Depression, Chemical; Female; Humans; M | 1976 |