mitotane has been researched along with Carcinoid Tumor in 3 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six to 10 months after hypercorticism was cured with ketoconazole and bilateral adrenalectomy, a thymic mass 2 to 5 cm in length was detected by computerized tomography or magnetic resonance imaging in all 3 patients." | 1.29 | [Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases]. ( Caillé, JM; Catargi, B; Drouillard, J; Greselle, JF; Laurent, F; Martigne, C; Roger, P; Tabarin, A, 1993) |
| "However, in adrenal cancer, urinary 17OHCS did not correlate with either plasma cortisol or urinary free cortisol, while the latter two parameters did." | 1.27 | Effect of o,p'-DDD on cortisol metabolism in Cushing's syndrome of various etiology. ( Inoue, S; Kawai, K; Koide, Y; Murayama, H; Yamashita, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabarin, A | 1 |
| Catargi, B | 1 |
| Laurent, F | 1 |
| Greselle, JF | 1 |
| Martigne, C | 1 |
| Caillé, JM | 1 |
| Drouillard, J | 1 |
| Roger, P | 1 |
| Koide, Y | 1 |
| Inoue, S | 1 |
| Murayama, H | 1 |
| Kawai, K | 1 |
| Yamashita, K | 1 |
| Schein, PS | 1 |
1 review available for mitotane and Carcinoid Tumor
| Article | Year |
|---|---|
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant | 1972 |
2 other studies available for mitotane and Carcinoid Tumor
| Article | Year |
|---|---|
[Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases].
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adult; Carcinoid Tumor; Cushing Syndrome; Drug Therapy, | 1993 |
Effect of o,p'-DDD on cortisol metabolism in Cushing's syndrome of various etiology.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1985 |