mitotane has been researched along with Bone Cancer in 5 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ranvier, GG | 1 |
| Inabnet, WB | 1 |
| Tanaka, K | 1 |
| Kumano, Y | 1 |
| Kanomata, N | 1 |
| Takeda, M | 1 |
| Hara, I | 1 |
| Fujisawa, M | 1 |
| Kawabata, G | 1 |
| Kamidono, S | 1 |
| Abiven, G | 1 |
| Coste, J | 1 |
| Groussin, L | 1 |
| Anract, P | 1 |
| Tissier, F | 1 |
| Legmann, P | 1 |
| Dousset, B | 1 |
| Bertagna, X | 1 |
| Bertherat, J | 1 |
| Hajjar, RA | 1 |
| Hickey, RC | 1 |
| Samaan, NA | 1 |
| Katsumi, T | 1 |
| Murayama, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma[NCT03145285] | Phase 2 | 10 participants (Anticipated) | Interventional | 2017-04-18 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitotane and Bone Cancer
| Article | Year |
|---|---|
Surgical management of adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; | 2015 |
Oncocytic adrenocortical carcinoma.
Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Combined Chemotherapy Protoc | 2004 |
3 other studies available for mitotane and Bone Cancer
| Article | Year |
|---|---|
Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients.
Topics: Adrenal Cortex Neoplasms; Adult; Analysis of Variance; Androgens; Antineoplastic Agents, Hormonal; B | 2006 |
Adrenal cortical carcinoma. A study of 32 patients.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Bone Neoplasms; Female; Hepa | 1975 |
[A case of non-functioning adrenal cortical carcinoma with pulmonary and bony metastases].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Bone Neoplasms; Combined Modality Th | 1989 |