mitotane has been researched along with Androgenization in 10 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenal Cancer is an infrequent and very aggressive tumor." | 2.48 | Giant adrenal carcinoma associated with renal vein and inferior vena cava thrombus. Case report and literature review. ( Fernández Arjona, M; Garrido Abad, P; Gómez de Vicente, JM; Herranz Fernández, LM; Jiménez Gálvez, M; Santos Arrontes, D; Suárez Fonseca, C, 2012) |
| "Androgen-secreting adrenal cancers are extremely rare malignancies, accounting for only a tiny proportion of the total number of women presenting with signs of androgen excess." | 2.46 | Androgen- and estrogen-secreting adrenal cancers. ( Bharwani, N; Cavlan, D; Grossman, A, 2010) |
| "Virilizing adrenal carcinoma is a rare disease, especially in women of reproductive age." | 2.39 | Virilizing adrenal carcinoma in a woman of reproductive age: a case presentation and literature review. ( Coonrod, DV; Rizkallah, TH, 1995) |
| "There months following surgery, liver metastases were documented associated with elevated levels of serum androgens." | 1.26 | Virilizing adrenal tumor in a child suppressed with dexamethasone for three years. Effect of o,p'-DDD on serum and urinary androgens. ( Korth-Schutz, S; Levine, LS; New, MI; Roth, JA; Saenger, P, 1977) |
| "Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization." | 1.25 | [Corticosuprarenaloma in children]. ( Benaily, M; Job, JC; Schweisguth, O, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavlan, D | 1 |
| Bharwani, N | 1 |
| Grossman, A | 1 |
| Hubertus, J | 1 |
| Boxberger, N | 1 |
| Redlich, A | 1 |
| von Schweinitz, D | 1 |
| Vorwerk, P | 1 |
| Garrido Abad, P | 1 |
| Gómez de Vicente, JM | 1 |
| Herranz Fernández, LM | 1 |
| Jiménez Gálvez, M | 1 |
| Santos Arrontes, D | 1 |
| Suárez Fonseca, C | 1 |
| Fernández Arjona, M | 1 |
| NETTO, AD | 1 |
| WAJCHENBERG, BL | 1 |
| RAVAGLIA, C | 1 |
| PEREIRA, VG | 1 |
| SHNAIDER, J | 1 |
| PUPO, AA | 1 |
| CINTRA, AB | 1 |
| Katsumata, N | 1 |
| Coonrod, DV | 1 |
| Rizkallah, TH | 1 |
| Benaily, M | 1 |
| Schweisguth, O | 1 |
| Job, JC | 1 |
| Korth-Schutz, S | 1 |
| Levine, LS | 1 |
| Roth, JA | 1 |
| Saenger, P | 1 |
| New, MI | 1 |
| Freeman, DA | 1 |
| Harrison, JH | 1 |
| Mahoney, EM | 1 |
| Bennett, AH | 1 |
5 reviews available for mitotane and Androgenization
| Article | Year |
|---|---|
Androgen- and estrogen-secreting adrenal cancers.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Algorithms; Androgens; Anti | 2010 |
Giant adrenal carcinoma associated with renal vein and inferior vena cava thrombus. Case report and literature review.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aged; Antineoplastic Agents; Carcinoma; Contraindications; F | 2012 |
[Virilizing adrenocortical tumor].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Androgens; Combined Modality Therapy; Diagnosis, Differenti | 2006 |
Virilizing adrenal carcinoma in a woman of reproductive age: a case presentation and literature review.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Carcinoma; Female; Hirsutism; Humans; Infertility, F | 1995 |
Steroid hormone-producing tumors in man.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androgens; C | 1986 |
5 other studies available for mitotane and Androgenization
| Article | Year |
|---|---|
Surgical aspects in the treatment of adrenocortical carcinomas in children: data of the GPOH-MET 97 trial.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents, Hormonal; Chemotherapy, | 2012 |
TREATMENT OF ADRENOCORTICAL CANCER WITH O,P'-DDD.
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenogenital Syndrome; Antineoplastic Agents; Ca | 1963 |
[Corticosuprarenaloma in children].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal G | 1975 |
Virilizing adrenal tumor in a child suppressed with dexamethasone for three years. Effect of o,p'-DDD on serum and urinary androgens.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Androgens; Child, Preschool; | 1977 |
Proceedings: Tumors of the adrenal cortex.
Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortico | 1973 |