Compounds > mitotane
Page last updated: 2024-10-31

mitotane and Adrenal Gland Diseases

mitotane has been researched along with Adrenal Gland Diseases in 4 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Adrenal Gland Diseases: Pathological processes of the ADRENAL GLANDS.

Research Excerpts

ExcerptRelevanceReference
"Medical therapy to control hypercortisolism in adrenal Cushing's syndrome is currently not the first-line therapy."2.66What is the role of medical therapy in adrenal-dependent Cushing's syndrome? ( Braun, LT; Reincke, M, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Braun, LT1
Reincke, M1
Rosenthal, KL1
Besser, GM1
Jeffcoate, WJ1
Sizonenko, PC1
Doret, AM1
Riondel, AM1
Paunier, L1

Reviews

2 reviews available for mitotane and Adrenal Gland Diseases

ArticleYear
What is the role of medical therapy in adrenal-dependent Cushing's syndrome?
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3

    Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH

2020
Adrenal gland disease in ferrets.
    The Veterinary clinics of North America. Small animal practice, 1997, Volume: 27, Issue:2

    Topics: Adrenal Cortex Function Tests; Adrenal Gland Diseases; Adrenal Glands; Animals; Antifungal Agents; A

1997

Other Studies

2 other studies available for mitotane and Adrenal Gland Diseases

ArticleYear
Endocrine and metabolic diseases. Adrenal diseases.
    British medical journal, 1976, Feb-21, Volume: 1, Issue:6007

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici

1976
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig

1974