mitotane and Adrenal Cortical Rest Tumor studies

mitotane and Adrenal Cortical Rest Tumor

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Research Excerpts

Excerpt	Relevance	Reference
"Cushing syndrome was diagnosed on the basis of a markedly elevated 24-hour urine free cortisol level and classic cushingoid features."	1.35	A patient with ectopic cortisol production derived from malignant testicular masses. ( Dluhy, RG; Jain, SH; Nosé, V; Sadow, PM, 2008)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	1 (25.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (25.00)

18.2507

2000's

1 (25.00)

29.6817

2010's

1 (25.00)

24.3611

2020's

1 (25.00)

2.80

Authors

Authors	Studies
Bachelot, A	1
Lapoirie, M	1
Dulon, J	1
Leban, M	1
Renard Penna, R	1
Touraine, P	1
Bry-Gauillard, H	1
Cartes, A	1
Young, J	1
Jain, SH	1
Sadow, PM	1
Nosé, V	1
Dluhy, RG	1
Ahlman, H	1
Jansson, S	1
Wängberg, B	1
Tisell, LE	1
Scherstén, T	1
Hansson, G	1
Bengtsson, BA	1
Ernest, I	1
Jakobsson, CE	1
Lindstedt, S	1

Studies

Bachelot, A

Lapoirie, M

Dulon, J

Leban, M

Renard Penna, R

Touraine, P

Bry-Gauillard, H

Cartes, A

Young, J

Jain, SH

Sadow, PM

Nosé, V

Dluhy, RG

Ahlman, H

Jansson, S

Wängberg, B

Tisell, LE

Scherstén, T

Hansson, G

Bengtsson, BA

Ernest, I

Jakobsson, CE

Lindstedt, S

Other Studies

4 other studies available for mitotane and Adrenal Cortical Rest Tumor

Article	Year
Effects of mitotane on testicular adrenal rest tumors in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a retrospective series of five patients. European journal of endocrinology, 2021, Volume: 184, Issue:3 Topics: Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Antineoplastic Agents, Hormonal; Humans;	2021
Mitotane for 21-hydroxylase deficiency in an infertile man. The New England journal of medicine, 2014, Nov-20, Volume: 371, Issue:21 Topics: Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Antineoplastic Agents, Hormonal; Azoospe	2014
A patient with ectopic cortisol production derived from malignant testicular masses. Nature clinical practice. Endocrinology & metabolism, 2008, Volume: 4, Issue:12 Topics: Adrenal Rest Tumor; Adrenocortical Carcinoma; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; H	2008
Adrenocortical carcinoma--diagnostic and therapeutical implications. The European journal of surgery = Acta chirurgica, 1993, Volume: 159, Issue:3 Topics: Adrenal Gland Neoplasms; Adrenal Rest Tumor; Adult; Aged; Carcinoma; Chemotherapy, Adjuvant; Female;	1993

Article

Year

Effects of mitotane on testicular adrenal rest tumors in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a retrospective series of five patients.

European journal of endocrinology, 2021, Volume: 184, Issue:3

Topics: Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Antineoplastic Agents, Hormonal; Humans;

2021

Mitotane for 21-hydroxylase deficiency in an infertile man.

The New England journal of medicine, 2014, Nov-20, Volume: 371, Issue:21

Topics: Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Antineoplastic Agents, Hormonal; Azoospe

2014

A patient with ectopic cortisol production derived from malignant testicular masses.

Nature clinical practice. Endocrinology & metabolism, 2008, Volume: 4, Issue:12

Topics: Adrenal Rest Tumor; Adrenocortical Carcinoma; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; H

2008

Adrenocortical carcinoma--diagnostic and therapeutical implications.

The European journal of surgery = Acta chirurgica, 1993, Volume: 159, Issue:3

Topics: Adrenal Gland Neoplasms; Adrenal Rest Tumor; Adult; Aged; Carcinoma; Chemotherapy, Adjuvant; Female;

1993