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mitotane and Adenomatosis, Familial Endocrine

mitotane has been researched along with Adenomatosis, Familial Endocrine in 2 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Research Excerpts

ExcerptRelevanceReference
" This dosage was maintained for an additional 16 weeks (cumulative dose 602 g, plasma MT maximum level 12 microg/ml), and then stopped because of sustained signs of hypoadrenalism requiring prednisone replacement."1.33A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex. ( Campo, M; Cignarelli, M; Giorgino, F; Logoluso, F; Margaglione, M; Marino, A; Picca, G, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Menaa, F1
Menaa, B1
Cignarelli, M1
Picca, G1
Campo, M1
Margaglione, M1
Marino, A1
Logoluso, F1
Giorgino, F1

Reviews

1 review available for mitotane and Adenomatosis, Familial Endocrine

ArticleYear
Development of mitotane lipid nanocarriers and enantiomers: two-in-one solution to efficiently treat adreno-cortical carcinoma.
    Current medicinal chemistry, 2012, Volume: 19, Issue:34

    Topics: Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Drug Carriers; Humans; Lipids; Mitotane;

2012

Other Studies

1 other study available for mitotane and Adenomatosis, Familial Endocrine

ArticleYear
A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:1

    Topics: Adrenal Cortex Diseases; Adrenal Glands; Adult; Antineoplastic Agents, Hormonal; DNA; Female; Humans

2005