mitotane has been researched along with Adenomatosis, Familial Endocrine in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This dosage was maintained for an additional 16 weeks (cumulative dose 602 g, plasma MT maximum level 12 microg/ml), and then stopped because of sustained signs of hypoadrenalism requiring prednisone replacement." | 1.33 | A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex. ( Campo, M; Cignarelli, M; Giorgino, F; Logoluso, F; Margaglione, M; Marino, A; Picca, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menaa, F | 1 |
| Menaa, B | 1 |
| Cignarelli, M | 1 |
| Picca, G | 1 |
| Campo, M | 1 |
| Margaglione, M | 1 |
| Marino, A | 1 |
| Logoluso, F | 1 |
| Giorgino, F | 1 |
1 review available for mitotane and Adenomatosis, Familial Endocrine
| Article | Year |
|---|---|
Development of mitotane lipid nanocarriers and enantiomers: two-in-one solution to efficiently treat adreno-cortical carcinoma.
Topics: Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Drug Carriers; Humans; Lipids; Mitotane; | 2012 |
1 other study available for mitotane and Adenomatosis, Familial Endocrine
| Article | Year |
|---|---|
A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.
Topics: Adrenal Cortex Diseases; Adrenal Glands; Adult; Antineoplastic Agents, Hormonal; DNA; Female; Humans | 2005 |