mitotane has been researched along with ACTH-Producing Pituitary Adenoma in 3 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medical therapy for Cushing's disease (CD) is currently based on agents mainly targeting adrenocortical function." | 1.39 | Mitotane reduces human and mouse ACTH-secreting pituitary cell viability and function. ( Ambrosio, MR; Degli Uberti, EC; Gentilin, E; Lapparelli, M; Minoia, M; Tagliati, F; Terzolo, M; Zatelli, MC; Zoli, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tritos, NA | 1 |
| Biller, BMK | 1 |
| Gentilin, E | 1 |
| Tagliati, F | 1 |
| Terzolo, M | 1 |
| Zoli, M | 1 |
| Lapparelli, M | 1 |
| Minoia, M | 1 |
| Ambrosio, MR | 1 |
| Degli Uberti, EC | 1 |
| Zatelli, MC | 1 |
| Broder, MS | 1 |
| Neary, MP | 1 |
| Chang, E | 1 |
| Cherepanov, D | 1 |
| Sun, GH | 1 |
| Ludlam, WH | 1 |
1 review available for mitotane and ACTH-Producing Pituitary Adenoma
| Article | Year |
|---|---|
Advances in the Medical Treatment of Cushing Disease.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Cabergoline; Endocrinology; Humans; Mifepristone; Mitotan | 2020 |
2 other studies available for mitotane and ACTH-Producing Pituitary Adenoma
| Article | Year |
|---|---|
Mitotane reduces human and mouse ACTH-secreting pituitary cell viability and function.
Topics: ACTH-Secreting Pituitary Adenoma; Adrenocorticotropic Hormone; Animals; Cell Line; Cell Survival; Co | 2013 |
Treatment patterns in Cushing's disease patients in two large United States nationwide databases: application of a novel, graphical methodology.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenalectomy; Adult; Antineoplastic Agents, Hormonal; Co | 2015 |