Page last updated: 2024-11-06

mitomycin and Weight Loss

mitomycin has been researched along with Weight Loss in 10 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Weight Loss: Decrease in existing BODY WEIGHT.

Research Excerpts

ExcerptRelevanceReference
"Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy."9.11The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004)
"Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy."5.11The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004)
"Deleterious oral mucositis (OM) develops during radiotherapy (RT) or chemoradiotherapy for head-and-neck cancer (HNC) patients."2.77Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer. ( Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH, 2012)
"Weight loss was common after HIPEC as 38 of 41 patients demonstrated weight loss."1.43Feeding tube placement during cytoreductive surgery and heated intraperitoneal chemotherapy does not improve postoperative nutrition and is associated with longer length of stay and higher readmission rates. ( Beaty, KA; Dineen, SP; Fournier, KF; Mansfield, PF; Rafeeq, S; Robinson, KA; Roland, CL; Royal, RE, 2016)
"Metastatic bronchioloalveolar carcinoma is an aggressive disease that is associated with a poor prognosis, similar to metastatic adenocarcinoma of the lung."1.28Metastatic bronchioloalveolar carcinoma and metastatic adenocarcinoma of the lung: comparison of clinical manifestations, chemotherapeutic responses, and prognosis. ( Eagan, RT; Feldman, ER; Schaid, DJ, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's2 (20.00)18.2507
2000's4 (40.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dineen, SP1
Robinson, KA1
Roland, CL1
Beaty, KA1
Rafeeq, S1
Mansfield, PF1
Royal, RE1
Fournier, KF1
Türkyilmaz, Z1
Sönmez, K1
Karabulut, R1
Gülbahar, O1
Poyraz, A1
Sancak, B1
Başaklar, AC1
Yen, SH1
Wang, LW1
Lin, YH1
Jen, YM1
Chung, YL1
Tebbutt, NC2
Norman, A2
Cunningham, D2
Iveson, T1
Seymour, M1
Hickish, T1
Harper, P1
Maisey, N1
Mochlinski, K1
Prior, Y1
Hill, M2
Kelleher, M1
Andreyev, J1
Allen, M1
Andreopoulou, E1
Ross, PJ1
O'Brien, ME1
Ford, HE1
Priest, K1
Eisen, T1
Norton, A1
Ashley, S1
Smith, IE1
Feldman, ER1
Eagan, RT1
Schaid, DJ1
Fumagalli, U1
Trabucchi, E1
Soligo, M1
Rosati, R1
Rebuffat, C1
Tonelli, C1
Montorsi, M1
Takagami, S1
Nishiyama, M1
Kim, R1
Kirihara, Y1
Jinushi, K1
Saeki, K1
Saeki, T1
Nosoh, Y1
Niimoto, M1
Hattori, T1
Allum, WH1
Hallissey, MT1
Kelly, KA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double Lung Transplant REgistry Aimed for Lung-limited Malignancies (DREAM) - a Prospective Observational Registry Study for Patients Undergoing Lung Transplantation for Medically Refractory Cancers Confined to the Lungs[NCT05671887]125 participants (Anticipated)Observational [Patient Registry]2022-11-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for mitomycin and Weight Loss

ArticleYear
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; E

2012
A multicentre, randomised phase III trial comparing protracted venous infusion (PVI) 5-fluorouracil (5-FU) with PVI 5-FU plus mitomycin C in patients with inoperable oesophago-gastric cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:10

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto

2002
Mitomycin C, carboplatin and protracted venous infusion 5-fluorouracil in advanced oesophago-gastric and pancreatic cancer: results of two phase II studies.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Esophageal Neoplasms; Fema

2003
The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:9

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin;

2004
Adjuvant chemotherapy in operable gastric cancer. 5 year follow-up of first British Stomach Cancer Group trial.
    Lancet (London, England), 1989, Mar-18, Volume: 1, Issue:8638

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy

1989

Other Studies

5 other studies available for mitomycin and Weight Loss

ArticleYear
Feeding tube placement during cytoreductive surgery and heated intraperitoneal chemotherapy does not improve postoperative nutrition and is associated with longer length of stay and higher readmission rates.
    The Journal of surgical research, 2016, Volume: 200, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Canc

2016
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
    Surgery, 2009, Volume: 145, Issue:2

    Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Mo

2009
Metastatic bronchioloalveolar carcinoma and metastatic adenocarcinoma of the lung: comparison of clinical manifestations, chemotherapeutic responses, and prognosis.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Age Factors; Aged; Antineoplastic Combin

1992
Effects of intraperitoneal chemotherapy on anastomotic healing in the rat.
    The Journal of surgical research, 1991, Volume: 50, Issue:1

    Topics: Anastomosis, Surgical; Animals; Hydroxyproline; Injections, Intraperitoneal; Injections, Intravenous

1991
[Comparative study on the anticancer activities of KW2149 and mitomycin C against human tumor xenografts using subrenal capsule assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Humans; Mice; Mice, Inbred Strains; Mitomyc

1989