mitomycin has been researched along with Urethral Neoplasms in 12 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Urethral Neoplasms: Cancer or tumors of the URETHRA. Benign epithelial tumors of the urethra usually consist of squamous and transitional cells. Primary urethral carcinomas are rare and typically of squamous cells. Urethral carcinoma is the only urological malignancy that is more common in females than in males.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From January 1991 to December 2006, 18 patients with invasive carcinoma of the male urethra referred to our institution were treated with a chemoradiation therapy protocol, consisting of 2 cycles of 5-fluorouracil (1,000 mg/m(2)) on days 1 to 4 and days 29 to 32, and mitomycin-C (10 mg/m(2)) on days 1 and 29 with concurrent external beam radiation therapy (45 to 55 Gy in 25 fractions during 5 weeks) to the genitalia, perineum, and inguinal and external iliac lymph nodes." | 3.74 | Coordinated chemoradiation therapy with genital preservation for the treatment of primary invasive carcinoma of the male urethra. ( Billmeyer, B; Cohen, MS; Girshovich, L; Hanley, RS; Oberfield, RA; Shuster, T; Triaca, V; Zinman, L, 2008) |
| "Patients with locally advanced squamous cell carcinoma of the bulbomembranous urethra fare poorly whether they undergo surgery or primary radiotherapy." | 1.29 | Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the bulbomembranous urethra: a case report. ( Huang, DT; Lutz, ST, 1995) |
| "Mitomycin C has proved to be useful as prophylaxis against superficial bladder tumor recurrences." | 1.27 | Prostatic recurrences in the management of superficial bladder tumors. ( Bondhus, MJ; Chaikin, L; Lockhart, JL; Politano, VA, 1983) |
| "In case 1, a 73-year-old female with squamous cell carcinoma was successfully treated with irradiation of 4,000 rad and peplomycin of 60 mg intravenously given." | 1.27 | [Female urethral carcinoma: results of irradiation in 2 patients]. ( Kanai, S; Kondo, A; Miyake, K; Okamura, K; Otani, T; Sahashi, M; Saitoh, M; Sakakibara, T; Shimozi, T; Takashi, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gakis, G | 1 |
| Morgan, TM | 1 |
| Daneshmand, S | 1 |
| Keegan, KA | 1 |
| Todenhöfer, T | 1 |
| Mischinger, J | 1 |
| Schubert, T | 1 |
| Zaid, HB | 1 |
| Hrbacek, J | 1 |
| Ali-El-Dein, B | 1 |
| Clayman, RH | 1 |
| Galland, S | 1 |
| Olugbade, K | 1 |
| Rink, M | 1 |
| Fritsche, HM | 1 |
| Burger, M | 1 |
| Chang, SS | 1 |
| Babjuk, M | 1 |
| Thalmann, GN | 1 |
| Stenzl, A | 1 |
| Efstathiou, JA | 1 |
| Quinlan, JF | 1 |
| North, J | 1 |
| Clarke, DA | 1 |
| Gwynne-Jones, DP | 1 |
| Cohen, MS | 1 |
| Triaca, V | 1 |
| Billmeyer, B | 1 |
| Hanley, RS | 1 |
| Girshovich, L | 2 |
| Shuster, T | 1 |
| Oberfield, RA | 2 |
| Zinman, L | 1 |
| Lockhart, JL | 1 |
| Chaikin, L | 1 |
| Bondhus, MJ | 1 |
| Politano, VA | 1 |
| Lutz, ST | 1 |
| Huang, DT | 1 |
| Licht, MR | 1 |
| Klein, EA | 1 |
| Bukowski, R | 1 |
| Montie, JE | 1 |
| Saxton, JP | 1 |
| Zinman, LN | 1 |
| Leibenhaut, M | 1 |
| Silverman, ML | 1 |
| Solsona, E | 1 |
| Iborra, I | 1 |
| Ricós, JV | 1 |
| Monrós, JL | 1 |
| Dumont, R | 1 |
| Casanova, J | 1 |
| Calabuig, C | 1 |
| Saitoh, M | 1 |
| Kondo, A | 1 |
| Sakakibara, T | 1 |
| Takashi, M | 1 |
| Sahashi, M | 1 |
| Kanai, S | 1 |
| Okamura, K | 1 |
| Shimozi, T | 1 |
| Miyake, K | 1 |
| Otani, T | 1 |
| Johnson, DW | 1 |
| Kessler, JF | 1 |
| Ferrigni, RG | 1 |
| Anderson, JD | 1 |
| van Helsdingen, PJ | 1 |
| Rikken, CH | 1 |
| Shah, AB | 1 |
| Kalra, JK | 1 |
| Silber, L | 1 |
| Molho, L | 1 |
1 trial available for mitomycin and Urethral Neoplasms
| Article | Year |
|---|---|
Recurrence of superficial bladder tumors in prostatic urethra.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma in Si | 1991 |
11 other studies available for mitomycin and Urethral Neoplasms
| Article | Year |
|---|---|
Impact of perioperative chemotherapy on survival in patients with advanced primary urethral cancer: results of the international collaboration on primary urethral carcinoma.
Topics: Adenocarcinoma; Aged; Albumin-Bound Paclitaxel; Antineoplastic Combined Chemotherapy Protocols; Carb | 2015 |
Radiation-induced osteonecrosis of the hips following genital-preserving surgery and chemoradiotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arthroplasty, Replacement, Hip; Carcinoma, Squ | 2009 |
Coordinated chemoradiation therapy with genital preservation for the treatment of primary invasive carcinoma of the male urethra.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Cohort Studies; Combined Modality | 2008 |
Prostatic recurrences in the management of superficial bladder tumors.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Humans; Male; Middle Aged; M | 1983 |
Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the bulbomembranous urethra: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; | 1995 |
Combination radiation and chemotherapy for the treatment of squamous cell carcinoma of the male and female urethra.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1995 |
Management of invasive squamous cell carcinoma of the bulbomembranous male urethra with co-ordinated chemo-radiotherapy and genital preservation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell; Comb | 1996 |
[Female urethral carcinoma: results of irradiation in 2 patients].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin | 1988 |
Low dose combined chemotherapy/radiotherapy in the management of locally advanced urethral squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Comb | 1989 |
Treatment of urothelial carcinoma of the upper urinary tract following prostatocystectomy with mitomycin C instillation in the ileal loop.
Topics: Aged; Carcinoma, Transitional Cell; Combined Modality Therapy; Humans; Ileum; Kidney Neoplasms; Male | 1986 |
Squamous cell cancer of female urethra. Successful treatment with chemoradiotherapy.
Topics: Aged; Biopsy; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Flu | 1985 |