mitomycin has been researched along with Tuberous Sclerosis in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
SUGIMURA, K | 1 |
Ohno, K | 1 |
Takeshita, K | 1 |
2 other studies available for mitomycin and Tuberous Sclerosis
Article | Year |
---|---|
[RENAL SARCOMA IN BOURNEVILLE-PRINGLE'S PHACOMATOSIS: CASE REPORT].
Topics: Humans; Kidney Neoplasms; Mitomycin; Mitomycins; Neoplasms; Nephrectomy; Neurocutaneous Syndromes; P | 1964 |
Patients with tuberous sclerosis have fibroblasts with normal limits for growth characteristics and sensitivities to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Cell Division; Cell Survival; Cells, Cultured; Child; D | 1984 |