Page last updated: 2024-11-06

mitomycin and Syndrome

mitomycin has been researched along with Syndrome in 28 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"To describe a case of ocular decompression syndrome in a patient after trabeculectomy with mitomycin C for neovascular glaucoma."7.70Diffuse retinal hemorrhages (ocular decompression syndrome) after trabeculectomy with mitomycin C for neovascular glaucoma. ( Danias, J; Podos, SM; Rosenbaum, J, 2000)
"We examined red cell fragmentation syndrome (RCFS) induced by mitomycin C (MMC) (13 patients), by thrombotic thrombocytopenic purpura (TTP) (17 patients), and by disseminated intravascular coagulation (DIC) (15 patients)."7.69Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C. ( Deguchi, K; Minami, N; Miyanishi, E; Nagaya, S; Oka, K; Tamaki, S; Tanigawa, M; Tsuzi, K; Wada, H; Wakita, Y, 1995)
"The scleral punch provides a safe and effective method for constructing and revising full-thickness sclerectomies in the nanophthalmic eye, minimizing the risk of choroidal trauma."5.35Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome. ( MacLaren, RE; Sabrosa, NA; Smith, HB, 2009)
" The dosage of mitomycin-C was 0."5.31Outcome of trabeculectomy with mitomycin-C in the iridocorneal endothelial syndrome. ( Aslanides, IM; Augsburger, JJ; Dudley, D; Lanzl, IM; Spaeth, GL; Wilson, RP, 2000)
"Seckel syndrome is a rare autosomal recessive disorder."5.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)
"We report a case of a rare complication after trabeculotomy combined with a small trabeculectomy with mitomycin C in a young patient with juvenile glaucoma."3.88Urrets-Zavalia Syndrome After Combined Trabeculotomy-Trabeculectomy Surgery. ( Gericke, A; Hoffmann, EM; Klezlova, A; Liebezeit, S; Pfeiffer, N; Prokosch-Willing, V, 2018)
"Trabeculectomy with mitomycin C might be effective in Cogan-Reese cases with glaucoma resistant to medical treatment."3.70Clinical and histopathologic findings of iris nevus (Cogan-Reese) syndrome. ( Coşar, CB; Kural, G; Onder, F; Ozdemir, Y; Usubütün, A, 1999)
"To describe a case of ocular decompression syndrome in a patient after trabeculectomy with mitomycin C for neovascular glaucoma."3.70Diffuse retinal hemorrhages (ocular decompression syndrome) after trabeculectomy with mitomycin C for neovascular glaucoma. ( Danias, J; Podos, SM; Rosenbaum, J, 2000)
"We examined red cell fragmentation syndrome (RCFS) induced by mitomycin C (MMC) (13 patients), by thrombotic thrombocytopenic purpura (TTP) (17 patients), and by disseminated intravascular coagulation (DIC) (15 patients)."3.69Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C. ( Deguchi, K; Minami, N; Miyanishi, E; Nagaya, S; Oka, K; Tamaki, S; Tanigawa, M; Tsuzi, K; Wada, H; Wakita, Y, 1995)
"Following gastrectomy for locally advanced adenocarcinomas, three patients developed microangiopathic hemolytic anemia and renal failure shortly after completing courses of adjuvant chemotherapy with mitomycin and 5-FU."3.66Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome. ( Band, PR; Bettez, P; Giroux, L; Gruber, J; Jolivet, J; Laurin, S, 1983)
"The scleral punch provides a safe and effective method for constructing and revising full-thickness sclerectomies in the nanophthalmic eye, minimizing the risk of choroidal trauma."1.35Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome. ( MacLaren, RE; Sabrosa, NA; Smith, HB, 2009)
" The dosage of mitomycin-C was 0."1.31Outcome of trabeculectomy with mitomycin-C in the iridocorneal endothelial syndrome. ( Aslanides, IM; Augsburger, JJ; Dudley, D; Lanzl, IM; Spaeth, GL; Wilson, RP, 2000)
"Seckel syndrome is a rare autosomal recessive disorder."1.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)
"These included cells from patients with Fanconi's anemia (FA), dyskeratosis congenita (DC) a disorder related to FA, Gardner's syndrome (GS) and xeroderma pigmentosum grop C (XPC)."1.27Suppression of cytotoxic effect of mitomycin-C by superoxide dismutase in Fanconi's anemia and dyskeratosis congenita fibroblasts. ( Little, JB; Nagasawa, H, 1983)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's8 (28.57)18.2507
2000's13 (46.43)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klezlova, A1
Liebezeit, S1
Prokosch-Willing, V1
Gericke, A1
Pfeiffer, N1
Hoffmann, EM1
Bharti, SK1
Khan, I1
Banerjee, T1
Sommers, JA1
Wu, Y1
Brosh, RM1
Sabrosa, NA1
Smith, HB1
MacLaren, RE1
van der Lelij, P1
Godthelp, BC1
van Zon, W1
van Gosliga, D1
Oostra, AB1
Steltenpool, J1
de Groot, J1
Scheper, RJ1
Wolthuis, RM1
Waisfisz, Q1
Darroudi, F1
Joenje, H1
de Winter, JP1
O'Driscoll, M1
Ruiz-Perez, VL1
Woods, CG1
Jeggo, PA1
Goodship, JA1
Bobabilla-Morales, L1
Corona-Rivera, A1
Corona-Rivera, JR1
Buenrostro, C1
García-Cobián, TA1
Corona-Rivera, E1
Cantú-Garza, JM1
García-Cruz, D1
Gueven, N1
Becherel, OJ1
Kijas, AW1
Chen, P1
Howe, O1
Rudolph, JH1
Gatti, R1
Date, H1
Onodera, O1
Taucher-Scholz, G1
Lavin, MF1
Saricaoglu, MS1
Sengun, A1
Karakurt, A1
Colluoglu, Z1
Schallenberg, M1
Steuhl, KP1
Selbach, JM1
Suzuki, Y1
Nishina, S1
Azuma, N1
Jolivet, J1
Giroux, L1
Laurin, S1
Gruber, J1
Bettez, P1
Band, PR1
Nagasawa, H1
Little, JB1
Nagaya, S1
Wada, H1
Oka, K1
Tanigawa, M1
Tamaki, S1
Tsuzi, K1
Miyanishi, E1
Wakita, Y1
Minami, N1
Deguchi, K1
Allingham-Hawkins, DJ2
Tomkins, DJ3
Van den Berg, DJ1
Francke, U1
Akduman, L1
Adelberg, DA1
Del Priore, LV1
Abou-Zahr, F1
Bejjani, B1
Kruyt, FA1
Kurg, R1
Bacino, C1
Shapira, SK1
Youssoufian, H1
Ozdemir, Y1
Onder, F1
Coşar, CB1
Usubütün, A1
Kural, G1
Kraakman-van der Zwet, M1
Overkamp, WJ1
Friedl, AA1
Klein, B1
Verhaegh, GW1
Jaspers, NG1
Midro, AT1
Eckardt-Schupp, F1
Lohman, PH1
Zdzienicka, MZ1
Lanzl, IM1
Wilson, RP1
Dudley, D1
Augsburger, JJ1
Aslanides, IM1
Spaeth, GL1
Danias, J1
Rosenbaum, J1
Podos, SM1
Yan, H1
Pestieau, SR1
Shmookler, BM1
Sugarbaker, PH2
Doe, EA1
Budenz, DL1
Gedde, SJ1
Imami, NR1
Burns, MA1
Butler, MG1
Hall, BD1
Maclean, RN1
Lozzio, CB1
Tada, H1
Ri, T1
Yoshida, H1
Ishimoto, K1
Kaneko, M1
Yamashiro, Y1
Shinohara, T1

Reviews

1 review available for mitomycin and Syndrome

ArticleYear
Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:14

    Topics: Abnormalities, Multiple; DEAD-box RNA Helicases; DNA Breaks; DNA Helicases; G-Quadruplexes; Genomic

2014

Other Studies

27 other studies available for mitomycin and Syndrome

ArticleYear
Urrets-Zavalia Syndrome After Combined Trabeculotomy-Trabeculectomy Surgery.
    Journal of glaucoma, 2018, Volume: 27, Issue:4

    Topics: Adult; Combined Modality Therapy; Glaucoma; Humans; Hydrophthalmos; Intraocular Pressure; Male; Mito

2018
Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009, Volume: 247, Issue:7

    Topics: Administration, Topical; Body Fluids; Cicatrix; Female; Humans; Microphthalmos; Middle Aged; Mitomyc

2009
The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2.
    PloS one, 2009, Sep-07, Volume: 4, Issue:9

    Topics: Acetyltransferases; Camptothecin; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Chromosome

2009
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome.
    Nature genetics, 2003, Volume: 33, Issue:4

    Topics: Ataxia Telangiectasia Mutated Proteins; Base Sequence; Cell Cycle Proteins; Cell Line; Chromosome Ma

2003
Chromosome instability induced in vitro with mitomycin C in five Seckel syndrome patients.
    American journal of medical genetics. Part A, 2003, Dec-01, Volume: 123A, Issue:2

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child, Preschool; Chromosomal Instability; Cytogenetic A

2003
Aprataxin, a novel protein that protects against genotoxic stress.
    Human molecular genetics, 2004, May-15, Volume: 13, Issue:10

    Topics: Apraxias; Ataxia; Ataxia Telangiectasia; Cell Culture Techniques; Chromatin; DNA Damage; DNA Repair;

2004
Autosomal dominant Weill-Marchesani syndrome and glaucoma management.
    Saudi medical journal, 2005, Volume: 26, Issue:9

    Topics: Abnormalities, Multiple; Adolescent; Chromosome Disorders; Dwarfism; Eye Abnormalities; Follow-Up St

2005
[Glaucoma with unilateral reddening of the eye].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2007, Volume: 104, Issue:6

    Topics: Antihypertensive Agents; Combined Modality Therapy; Drug Therapy, Combination; Female; Glaucoma, Ope

2007
Scleral window surgery and topical mitomycin C for nanophthalmic uveal effusion complicated by renal failure: case report.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:5

    Topics: Administration, Topical; Adolescent; Antibiotics, Antineoplastic; Choroid; Exudates and Transudates;

2007
Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome.
    Cancer treatment reports, 1983, Volume: 67, Issue:5

    Topics: Adenocarcinoma; Adult; Anemia, Hemolytic; Drug Therapy, Combination; Female; Fluorouracil; Humans; K

1983
Suppression of cytotoxic effect of mitomycin-C by superoxide dismutase in Fanconi's anemia and dyskeratosis congenita fibroblasts.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Adolescent; Adult; Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Child; F

1983
Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C.
    American journal of hematology, 1995, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Cytokines; Disseminated Intravascular

1995
Heterogeneity in Roberts syndrome.
    American journal of medical genetics, 1995, Jan-16, Volume: 55, Issue:2

    Topics: Abnormalities, Multiple; Cell Line; Developmental Disabilities; Female; Genetic Heterogeneity; Growt

1995
Sensitivity of Roberts syndrome cells to gamma radiation, mitomycin C, and protein synthesis inhibitors.
    Somatic cell and molecular genetics, 1993, Volume: 19, Issue:4

    Topics: Abnormalities, Multiple; Cell Cycle; Cell Division; Cell Line; Demecolcine; Dose-Response Relationsh

1993
Nanophthalmic uveal effusion managed with scleral windows and topical mitomycin-C.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:4

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Exudates and Tr

1997
Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome.
    American journal of medical genetics, 1999, Apr-23, Volume: 83, Issue:5

    Topics: Abnormalities, Multiple; Blotting, Western; Cell Cycle Proteins; Child; Child, Preschool; DNA-Bindin

1999
Clinical and histopathologic findings of iris nevus (Cogan-Reese) syndrome.
    Acta ophthalmologica Scandinavica, 1999, Volume: 77, Issue:2

    Topics: Adult; Corneal Edema; Glaucoma; Humans; Intraocular Pressure; Iris Neoplasms; Male; Mitomycin; Nevus

1999
Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts.
    Mutation research, 1999, May-14, Volume: 434, Issue:1

    Topics: Abnormalities, Multiple; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Line; Cell Line, Trans

1999
Outcome of trabeculectomy with mitomycin-C in the iridocorneal endothelial syndrome.
    Ophthalmology, 2000, Volume: 107, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Corneal Diseases; Endothelium,

2000
Diffuse retinal hemorrhages (ocular decompression syndrome) after trabeculectomy with mitomycin C for neovascular glaucoma.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:4

    Topics: Aged; Antimetabolites; Glaucoma, Neovascular; Humans; Intraocular Pressure; Male; Mitomycin; Retinal

2000
Histopathologic analysis in 46 patients with pseudomyxoma peritonei syndrome: failure versus success with a second-look operation.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2001, Volume: 14, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic;

2001
Cytoreductive surgery and peri-operative intraperitoneal chemotherapy as a curative approach to pseudomyxoma peritonei syndrome.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2001, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Digestive Syste

2001
Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.
    Ophthalmology, 2001, Volume: 108, Issue:10

    Topics: Adult; Antihypertensive Agents; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follow-Up Stud

2001
Somatic cell hybridization of Roberts syndrome and normal lymphoblasts resulting in correction of both the cytogenetic and mutagen hypersensitivity cellular phenotypes.
    Somatic cell and molecular genetics, 1991, Volume: 17, Issue:5

    Topics: Abnormalities, Multiple; Child, Preschool; Dose-Response Relationship, Drug; Female; Genes, Recessiv

1991
Hypersensitivity to mitomycin C cell-killing in Roberts syndrome fibroblasts with, but not without, the heterochromatin abnormality.
    Mutation research, 1989, Volume: 216, Issue:5

    Topics: Abnormalities, Multiple; Cells, Cultured; Fibroblasts; Heterochromatin; Humans; Mitomycin; Mitomycin

1989
Do some patients with Seckel syndrome have hematological problems and/or chromosome breakage?
    American journal of medical genetics, 1987, Volume: 27, Issue:3

    Topics: Abnormalities, Multiple; Adolescent; Child; Chromosome Aberrations; Chromosome Fragility; Chromosome

1987
A case of Shwachman syndrome with increased spontaneous chromosome breakage.
    Human genetics, 1987, Volume: 77, Issue:3

    Topics: Bone Marrow Diseases; Chromosome Aberrations; Chromosome Fragility; Exocrine Pancreatic Insufficienc

1987