Page last updated: 2024-11-06

mitomycin and Stunted Growth

mitomycin has been researched along with Stunted Growth in 7 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Seckel syndrome is a rare autosomal recessive disorder."5.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)
" Compared with Fancc(-)(/)(-) mice lacking FANCC, a component of the FA core complex, Helq(gt/gt) mice exhibited a mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker mitomycin C."3.79Helq acts in parallel to Fancc to suppress replication-associated genome instability. ( Akre, MK; Johnson, CS; Kawabata, T; Lee, WL; Luebben, SW; O'Sullivan, MG; Shima, N, 2013)
"Seckel syndrome is a rare autosomal recessive disorder."1.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luebben, SW1
Kawabata, T1
Akre, MK1
Lee, WL1
Johnson, CS1
O'Sullivan, MG1
Shima, N1
Auerbach, AD1
van der Lelij, P1
Godthelp, BC1
van Zon, W1
van Gosliga, D1
Oostra, AB1
Steltenpool, J1
de Groot, J1
Scheper, RJ1
Wolthuis, RM1
Waisfisz, Q1
Darroudi, F1
Joenje, H1
de Winter, JP1
Bobabilla-Morales, L1
Corona-Rivera, A1
Corona-Rivera, JR1
Buenrostro, C1
García-Cobián, TA1
Corona-Rivera, E1
Cantú-Garza, JM1
García-Cruz, D1
Allingham-Hawkins, DJ2
Tomkins, DJ2
Abou-Zahr, F1
Bejjani, B1
Kruyt, FA1
Kurg, R1
Bacino, C1
Shapira, SK1
Youssoufian, H1

Reviews

1 review available for mitomycin and Stunted Growth

ArticleYear
Fanconi anemia and its diagnosis.
    Mutation research, 2009, Jul-31, Volume: 668, Issue:1-2

    Topics: Congenital Abnormalities; DNA Damage; Endocrine System Diseases; Epoxy Compounds; Fanconi Anemia; Ge

2009

Other Studies

6 other studies available for mitomycin and Stunted Growth

ArticleYear
Helq acts in parallel to Fancc to suppress replication-associated genome instability.
    Nucleic acids research, 2013, Volume: 41, Issue:22

    Topics: Alleles; Animals; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cross-Linking Reagents; DNA He

2013
The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2.
    PloS one, 2009, Sep-07, Volume: 4, Issue:9

    Topics: Acetyltransferases; Camptothecin; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Chromosome

2009
Chromosome instability induced in vitro with mitomycin C in five Seckel syndrome patients.
    American journal of medical genetics. Part A, 2003, Dec-01, Volume: 123A, Issue:2

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child, Preschool; Chromosomal Instability; Cytogenetic A

2003
Heterogeneity in Roberts syndrome.
    American journal of medical genetics, 1995, Jan-16, Volume: 55, Issue:2

    Topics: Abnormalities, Multiple; Cell Line; Developmental Disabilities; Female; Genetic Heterogeneity; Growt

1995
Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome.
    American journal of medical genetics, 1999, Apr-23, Volume: 83, Issue:5

    Topics: Abnormalities, Multiple; Blotting, Western; Cell Cycle Proteins; Child; Child, Preschool; DNA-Bindin

1999
Somatic cell hybridization of Roberts syndrome and normal lymphoblasts resulting in correction of both the cytogenetic and mutagen hypersensitivity cellular phenotypes.
    Somatic cell and molecular genetics, 1991, Volume: 17, Issue:5

    Topics: Abnormalities, Multiple; Child, Preschool; Dose-Response Relationship, Drug; Female; Genes, Recessiv

1991