mitomycin has been researched along with Strabismus in 9 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of mitomycin C in reducing postoperative adhesions following strabismus surgery." | 9.11 | Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery. ( Chen, PL; Chen, WY; Lu, DW, 2005) |
| "The present study aimed to investigate the efficacy of mitomycin-C (MMC) and infliximab (INF) in reducing adhesion and fibrosis following strabismus surgery." | 7.83 | Efficacy of mitomycin-C and infliximab in reducing adhesionand fibrosis following strabismus surgery. ( Çoşkun Yılmaz, B; Dinç, E; Güçlü, ES; Özcan Metin, T; Sarı, AA; Taşdelen, B, 2016) |
| "To investigate whether mycophenolic acid (MPA) exerts antifibrotic effects on pterygium fibroblasts (PFB) with and without stimulation with fibrogenic cytokines, and to compare the efficacy of MPA with mitomycin (MMC) and dexamethasone (DXM) on PFB and tenon fibroblasts (TFB)." | 7.76 | Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro. ( Amer, R; Levi-Schaffer, F; Maftsir, G; Puxeddu, I; Rabinowich, L; Solomon, A, 2010) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 7.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To evaluate the efficiency of mitomycin C (MMC) in limiting the postoperative inflammatory response and scarring after strabismus surgery." | 7.70 | Histologic effect of mitomycin C on strabismus surgery in the rabbit. ( Akaishi, PM; De Luca, IM; Minguini, N; Monteiro de Carvalho, KM, 2000) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 7.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "The aim of this study was to evaluate the efficacy of mitomycin C in reducing postoperative adhesions following strabismus surgery." | 5.11 | Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery. ( Chen, PL; Chen, WY; Lu, DW, 2005) |
| "The present study aimed to investigate the efficacy of mitomycin-C (MMC) and infliximab (INF) in reducing adhesion and fibrosis following strabismus surgery." | 3.83 | Efficacy of mitomycin-C and infliximab in reducing adhesionand fibrosis following strabismus surgery. ( Çoşkun Yılmaz, B; Dinç, E; Güçlü, ES; Özcan Metin, T; Sarı, AA; Taşdelen, B, 2016) |
| "To investigate whether mycophenolic acid (MPA) exerts antifibrotic effects on pterygium fibroblasts (PFB) with and without stimulation with fibrogenic cytokines, and to compare the efficacy of MPA with mitomycin (MMC) and dexamethasone (DXM) on PFB and tenon fibroblasts (TFB)." | 3.76 | Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro. ( Amer, R; Levi-Schaffer, F; Maftsir, G; Puxeddu, I; Rabinowich, L; Solomon, A, 2010) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 3.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To evaluate the efficiency of mitomycin C (MMC) in limiting the postoperative inflammatory response and scarring after strabismus surgery." | 3.70 | Histologic effect of mitomycin C on strabismus surgery in the rabbit. ( Akaishi, PM; De Luca, IM; Minguini, N; Monteiro de Carvalho, KM, 2000) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 3.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Güçlü, ES | 1 |
| Sarı, AA | 1 |
| Dinç, E | 1 |
| Özcan Metin, T | 1 |
| Çoşkun Yılmaz, B | 1 |
| Taşdelen, B | 1 |
| Amer, R | 1 |
| Rabinowich, L | 1 |
| Maftsir, G | 1 |
| Puxeddu, I | 1 |
| Levi-Schaffer, F | 1 |
| Solomon, A | 1 |
| Choi, S | 1 |
| Cheong, Y | 1 |
| Shin, JH | 1 |
| Kim, KA | 1 |
| Bang, JB | 1 |
| Jin, KH | 1 |
| Park, HK | 1 |
| Eşme, A | 1 |
| Yildirim, C | 1 |
| Tatlipinar, S | 1 |
| Düzcan, E | 1 |
| Yaylali, V | 1 |
| Ozden, S | 1 |
| Chen, PL | 1 |
| Chen, WY | 1 |
| Lu, DW | 1 |
| Oh, SO | 1 |
| Chang, BL | 1 |
| Lee, J | 1 |
| Heilmann, C | 1 |
| Schönfeld, P | 1 |
| Schlüter, T | 1 |
| Bohnensack, R | 1 |
| Behrens-Baumann, W | 1 |
| Mora, JS | 1 |
| Sprunger, DT | 1 |
| Helveston, EM | 1 |
| Evan, AP | 1 |
| Minguini, N | 1 |
| Monteiro de Carvalho, KM | 1 |
| Akaishi, PM | 1 |
| De Luca, IM | 1 |
1 trial available for mitomycin and Strabismus
| Article | Year |
|---|---|
Evaluation of mitomycin C in reducing postoperative adhesions in strabismus surgery.
Topics: Adult; Aged; Double-Blind Method; Humans; Middle Aged; Mitomycin; Postoperative Complications; Prosp | 2005 |
8 other studies available for mitomycin and Strabismus
| Article | Year |
|---|---|
Efficacy of mitomycin-C and infliximab in reducing adhesionand fibrosis following strabismus surgery.
Topics: Animals; Infliximab; Mitomycin; Oculomotor Muscles; Postoperative Complications; Rabbits; Strabismus | 2016 |
Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro.
Topics: Adult; Aged; Analysis of Variance; Apoptosis; Cell Proliferation; Cells, Cultured; Dexamethasone; Do | 2010 |
Short-term response of mitomycin C on the human rectus muscle following strabismus surgery: histological, ultrastructural, and biomechanical evaluation.
Topics: Histocytochemistry; Humans; Immunohistochemistry; Inflammation; Microscopy, Atomic Force; Microscopy | 2013 |
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo | 2004 |
Effects of mitomycin C on delayed adjustment in experimental strabismus surgery.
Topics: Administration, Topical; Animals; Chemotherapy, Adjuvant; Conjunctiva; Mitomycin; Oculomotor Muscles | 1995 |
Effect of the cytostatic agent idarubicin on fibroblasts of the human Tenon's capsule compared with mitomycin C.
Topics: Antibiotics, Antineoplastic; Apoptosis; Cell Count; Cell Division; Dose-Response Relationship, Drug; | 1999 |
Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery.
Topics: Administration, Topical; Animals; Antimetabolites; Cicatrix; Conjunctiva; Fluorouracil; Intraoperati | 1997 |
Histologic effect of mitomycin C on strabismus surgery in the rabbit.
Topics: Animals; Antimetabolites; Cicatrix; Granuloma; Intraoperative Care; Mitomycin; Oculomotor Muscles; P | 2000 |