mitomycin has been researched along with Spinocerebellar Ataxias in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Spinocerebellar Ataxias: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rate of chromosomal aberrations was normal in AOA2 cells after treatment with CPT, MMC, H₂O₂ and X-rays." | 1.37 | Role of senataxin in DNA damage and telomeric stability. ( Chessa, L; De Amicis, A; Delia, D; Fanciulli, M; Ferrari, F; Piane, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ponger, P | 1 |
| Kurolap, A | 1 |
| Lerer, I | 1 |
| Dagan, J | 1 |
| Chai Gadot, C | 1 |
| Mory, A | 1 |
| Wilnai, Y | 1 |
| Oniashvili, N | 1 |
| Giladi, N | 1 |
| Gurevich, T | 1 |
| Meiner, V | 1 |
| Lossos, A | 1 |
| Baris Feldman, H | 1 |
| De Amicis, A | 1 |
| Piane, M | 1 |
| Ferrari, F | 1 |
| Fanciulli, M | 1 |
| Delia, D | 1 |
| Chessa, L | 1 |
2 other studies available for mitomycin and Spinocerebellar Ataxias
| Article | Year |
|---|---|
Unique Ataxia-Oculomotor Apraxia 2 (AOA2) in Israel with Novel Variants, Atypical Late Presentation, and Possible Identification of a Poison Exon.
Topics: Adolescent; Apraxias; Codon, Nonsense; DNA Helicases; Exons; Humans; Israel; Mitomycin; Multifunctio | 2022 |
Role of senataxin in DNA damage and telomeric stability.
Topics: Camptothecin; Cell Line, Tumor; Chromosome Aberrations; DNA Damage; DNA Helicases; DNA Repair; Human | 2011 |