Page last updated: 2024-11-06

mitomycin and Soft Tissue Neoplasms

mitomycin has been researched along with Soft Tissue Neoplasms in 9 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Research Excerpts

ExcerptRelevanceReference
"Between March 1994 and October 1997, 20 women and 19 men with primary extremity or limb girdle high-grade soft tissue sarcomas were registered to a study of preoperative ifosfamide, mitomycin, doxorubicin, cisplatin (IMAP) plus granulocyte macrophage-colony-stimulating factor (GM-CSF) followed by preoperative irradiation and subsequent limb-sparing surgery."9.10Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor. ( Buckner, JC; Edmonson, JH; Foo, ML; Gunderson, LL; Haddock, MG; Mahoney, MR; Maples, WJ; O'Connor, MI; Petersen, IA; Pritchard, DJ; Rock, MG; Shives, TC; Sim, FH; Stafford, SL, 2002)
"Patients with high-grade soft tissue sarcomas were treated with 2 cycles of ifosfamide, mitomycin, doxorubicin, and cisplatin plus GM-CSF subcutaneous followed by 45 Gy irradiation with concurrent 2 cycles of mitomycin, doxorubicin, and cisplatin followed by surgery +/- intraoperative radiation or brachytherapy."5.22Chemotherapy, Irradiation, and Surgery for Function-preserving Curative Therapy of Primary Extremity Soft Tissue Sarcomas: Initial Treatment With I-MAP and Inhalation GM-CSF During Preoperative Irradiation and Postoperatively. ( Haddock, M; Mahoney, M; Maples, W; Markovic, SN; O'Connor, MI; Okuno, S; Petersen, I; Shives, T; Sim, F, 2016)
"Between March 1994 and October 1997, 20 women and 19 men with primary extremity or limb girdle high-grade soft tissue sarcomas were registered to a study of preoperative ifosfamide, mitomycin, doxorubicin, cisplatin (IMAP) plus granulocyte macrophage-colony-stimulating factor (GM-CSF) followed by preoperative irradiation and subsequent limb-sparing surgery."5.10Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor. ( Buckner, JC; Edmonson, JH; Foo, ML; Gunderson, LL; Haddock, MG; Mahoney, MR; Maples, WJ; O'Connor, MI; Petersen, IA; Pritchard, DJ; Rock, MG; Shives, TC; Sim, FH; Stafford, SL, 2002)
"The aim of this study was to compare the treatment efficacy of mitomycin-C plus tamoxifen (MT) to adriamycin, dibromodulcitol and tamoxifen (DAT) in previously treated patients with metastatic breast cancer."5.05A pilot study of mitomycin-C and tamoxifen (MT) versus dibromodulcitol, adriamycin, and tamoxifen (DAT). ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1982)
"Alveolar soft part sarcoma is a rare soft tissue tumor arising in extremities."1.27[Pulmonary manifestations of alveolar soft part sarcoma; bronchial arterial embolization for hemoptysis]. ( Kikuchi, K; Masuda, H; Ogata, T; Takagi, K; Tanaka, S, 1988)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sio, TT1
Vu, CC1
Sohawon, S1
Van Houtte, P1
Thariat, J1
Novotny, PJ1
Miller, RC1
Bar-Sela, G1
Okuno, S1
Petersen, I1
Shives, T1
Mahoney, M1
Haddock, M1
Sim, F1
O'Connor, MI2
Markovic, SN1
Maples, W1
Takeuchi, S2
Akahoshi, Y1
Kasai, C2
Nishimoto, Y1
Chang, YC1
Falkson, G1
Tormey, DC1
Crowley, J1
Edmonson, JH1
Petersen, IA1
Shives, TC1
Mahoney, MR1
Rock, MG1
Haddock, MG1
Sim, FH1
Maples, WJ1
Gunderson, LL1
Foo, ML1
Pritchard, DJ1
Buckner, JC1
Stafford, SL1
Sato, M1
Kushida, Y1
Matsunaga, T1
Masuda, H1
Ogata, T1
Kikuchi, K1
Takagi, K1
Tanaka, S1
van Oosterom, AT1
Santoro, A1
Bramwell, V1
Davy, M1
Mouridsen, HT1
Thomas, D1
Sylvester, R1
Di Lauro, L1
Balice, A1
Papaldo, P1
Lopez, M1

Trials

3 trials available for mitomycin and Soft Tissue Neoplasms

ArticleYear
Chemotherapy, Irradiation, and Surgery for Function-preserving Curative Therapy of Primary Extremity Soft Tissue Sarcomas: Initial Treatment With I-MAP and Inhalation GM-CSF During Preoperative Irradiation and Postoperatively.
    American journal of clinical oncology, 2016, Volume: 39, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin;

2016
A pilot study of mitomycin-C and tamoxifen (MT) versus dibromodulcitol, adriamycin, and tamoxifen (DAT).
    American journal of clinical oncology, 1982, Volume: 5, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

1982
Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor.
    Cancer, 2002, Feb-01, Volume: 94, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined

2002

Other Studies

6 other studies available for mitomycin and Soft Tissue Neoplasms

ArticleYear
Extraskeletal Osteosarcoma: An International Rare Cancer Network Study.
    American journal of clinical oncology, 2016, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc

2016
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide;

1984
[Clinical studies on preoperative continuous intra-arterial chemotherapy in the treatment of malignant soft tissue tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cisplatin;

1991
[Pulmonary manifestations of alveolar soft part sarcoma; bronchial arterial embolization for hemoptysis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Adult; Bronchial Arteries; Combined Modality Therapy; Embolization, Therapeutic; Hemoptysis; Humans;

1988
Mitomycin C (MCC) in advanced soft tissue sarcoma: a phase II study of the EORTC Soft Tissue and Bone Sarcoma Group.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Sarcoma; Sof

1985
[Mitomycin C in the treatment of sarcomas of the soft tissues in the adult in an advanced phase].
    La Clinica terapeutica, 1985, Oct-31, Volume: 115, Issue:2

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Sarcoma; Sof

1985