mitomycin has been researched along with Signet Ring Cell Carcinoma in 11 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Signet ring cell gastric cancer (SRCGC) has very poor prognosis worldwide, and studying its molecular characteristics is urgent for improving the outcome." | 1.42 | Establishment and characterization of GCSR1, a multi-drug resistant signet ring cell gastric cancer cell line. ( Cao, J; Feng, JG; Gu, LH; He, KF; Jin, KT; Li, GL; Qian, LJ; Su, XY; Teng, LS; Wang, HH; Xu, X; Xu, ZZ; Zhang, J; Zhou, Q, 2015) |
| "Fresh samples of gastric cancer obtained from operation room were prepared to single-cell suspension (3 x 10(5) to 5 x 10(5) cells ml(-1)) and were separately exposed to taxol (TAX), cisplatin (CDDP), 5-fluorouracil (5-Fu), adriamycin (ADM), mitomycin (MMC) for 48 hours." | 1.34 | [Anti-tumor effects of chemotherapeutic drugs on human gastric cancer cells in vitro and the relationship with expression of hTERT mRNA]. ( Cao, YC; Fu, ZJ; Geng, M; Tai, YH; Wang, XY; Yin, YC, 2007) |
| "Six patients with gastric cancer, stage IIIA to IV, received intraabdominal cisplatin (CDDP) at laporotomy." | 1.31 | [Postoperative adjuvant immunochemotherapy using Lentinan for advanced gastric carcinoma patients with metastasis in the regional lymph nodes and serosal invasion]. ( Kagawa, R; Nakayama, N; Sakata, S; Tada, M; Yamaguchi, T, 2002) |
| "The role in colorectal cancer is less clear, although there are some reports that suggest a benefit." | 1.30 | Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer. ( Clingan, P; Horsell, KW; King, DW; Merten, S; Morris, DL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 1 |
| Li, PF | 1 |
| Geng, M | 2 |
| Cao, YC | 2 |
| Yin, YC | 2 |
| Xu, X | 1 |
| Qian, LJ | 1 |
| Su, XY | 1 |
| He, KF | 1 |
| Jin, KT | 1 |
| Gu, LH | 1 |
| Feng, JG | 1 |
| Li, GL | 1 |
| Zhou, Q | 1 |
| Xu, ZZ | 1 |
| Wang, HH | 1 |
| Zhang, J | 1 |
| Cao, J | 1 |
| Teng, LS | 1 |
| Kanagavel, D | 1 |
| Pokataev, IA | 1 |
| Fedyanin, MY | 1 |
| Tryakin, AA | 1 |
| Bazin, IS | 1 |
| Narimanov, MN | 1 |
| Yakovleva, ES | 1 |
| Garin, AM | 1 |
| Tjulandin, SA | 1 |
| Yang, XJ | 1 |
| Huang, CQ | 1 |
| Suo, T | 1 |
| Mei, LJ | 1 |
| Yang, GL | 1 |
| Cheng, FL | 1 |
| Zhou, YF | 1 |
| Xiong, B | 1 |
| Yonemura, Y | 1 |
| Li, Y | 1 |
| Kagawa, R | 1 |
| Nakayama, N | 1 |
| Yamaguchi, T | 1 |
| Sakata, S | 1 |
| Tada, M | 1 |
| Reingruber, B | 1 |
| Boettcher, MI | 1 |
| Klein, P | 1 |
| Hohenberger, W | 1 |
| Pelz, JO | 1 |
| Fu, ZJ | 1 |
| Wang, XY | 1 |
| Tai, YH | 1 |
| Miyazaki, N | 1 |
| Ohkura, H | 1 |
| Kajimura, N | 1 |
| Okazaki, N | 1 |
| Horsell, KW | 1 |
| Merten, S | 1 |
| Clingan, P | 1 |
| King, DW | 1 |
| Morris, DL | 1 |
| Michiwa, Y | 1 |
| Earashi, M | 1 |
| Kobayashi, H | 1 |
| Matsuki, N | 1 |
| Fujimoto, T | 1 |
| Zhang, B | 1 |
| Minami, S | 1 |
| Wang, X | 1 |
| Takahashi, Y | 1 |
| Mai, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Combined With Sintilimab in Gastric Cancer With Peritoneal Metastasis[NCT05648487] | Phase 2 | 46 participants (Anticipated) | Interventional | 2023-01-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for mitomycin and Signet Ring Cell Carcinoma
| Article | Year |
|---|---|
A prognostic model in patients treated for metastatic gastric cancer with second-line chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring | 2010 |
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2011 |
9 other studies available for mitomycin and Signet Ring Cell Carcinoma
| Article | Year |
|---|---|
Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Antineoplastic Agents; Biomarke | 2013 |
Establishment and characterization of GCSR1, a multi-drug resistant signet ring cell gastric cancer cell line.
Topics: Animals; Carcinoma, Signet Ring Cell; Cell Line, Tumor; Cell Proliferation; China; Drug Resistance, | 2015 |
[Postoperative adjuvant immunochemotherapy using Lentinan for advanced gastric carcinoma patients with metastasis in the regional lymph nodes and serosal invasion].
Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2002 |
Hyperthermic intraperitoneal chemoperfusion is an option for treatment of peritoneal carcinomatosis in children.
Topics: Antibiotics, Antineoplastic; Carcinoma, Signet Ring Cell; Chemotherapy, Cancer, Regional Perfusion; | 2007 |
[Anti-tumor effects of chemotherapeutic drugs on human gastric cancer cells in vitro and the relationship with expression of hTERT mRNA].
Topics: Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Adult; Aged; Antibiotics, Antineoplastic; Antim | 2007 |
Semiautomated 14C-thymidine incorporation assay for in vitro screening of anticancer drug.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Signet Ring Cell; Cell Divis | 1993 |
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer.
Topics: Abscess; Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; | 1999 |
Cutaneous metastases from gastric adenocarcinoma treated with combination chemotherapy producing complete response with long survival.
Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ri | 2001 |
Evaluation of intraoperative intraperitoneal cytology for advanced gastric carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Car | 2002 |