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mitomycin and Sclera Diseases

mitomycin has been researched along with Sclera Diseases in 24 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C."8.81Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002)
"To describe complications after use of mitomycin C (MMC) as a surgical adjuvant in pterygium surgery."7.81Mitomycin C-associated scleral stromalysis after pterygium surgery. ( Lee, WB; Lindquist, TP, 2015)
"To report a case of scleral melting noted 16 years after pterygium excision with postoperative adjuvant topical Mitomycin C (MMC)."7.73Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy. ( Azwa, JA; Ibrahim, M; Raihan, IS; Wan Norliza, WM, 2006)
"To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits."7.72Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004)
" Thirty-three months before, the patient had a pterygium excised and mitomycin C, 0."7.68Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy. ( Fujitani, A; Hayasaka, S; Noda, S; Shibuya, Y, 1993)
"The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing."7.68Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992)
" Although topical mitomycin-C is effective as an adjunct to pterygium surgery and may reduce recurrence, the safety and efficacy of various concentrations and dosing schedules need further definition."5.29Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. ( Dougherty, PJ; Hardten, DR; Lindstrom, RL, 1996)
"To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C."4.81Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002)
"The objective of this study is to investigate the results of an adaptive approach of bleb revision surgery for late onset hypotony after trabeculectomy with mitomycin C because of bleb leakage and/or scleral melting."3.88Results of an Adaptive Surgical Approach for Managing Late Onset Hypotony After Trabeculectomy With Mitomycin C. ( Hoffmann, EM; Lamparter, J; Pfeiffer, N; Prokosch-Willing, V; Toshev, AP; Ul Hassan, SN, 2018)
"To describe complications after use of mitomycin C (MMC) as a surgical adjuvant in pterygium surgery."3.81Mitomycin C-associated scleral stromalysis after pterygium surgery. ( Lee, WB; Lindquist, TP, 2015)
"To report a case of scleral melting noted 16 years after pterygium excision with postoperative adjuvant topical Mitomycin C (MMC)."3.73Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy. ( Azwa, JA; Ibrahim, M; Raihan, IS; Wan Norliza, WM, 2006)
"To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits."3.72Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004)
" Thirty-three months before, the patient had a pterygium excised and mitomycin C, 0."3.68Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy. ( Fujitani, A; Hayasaka, S; Noda, S; Shibuya, Y, 1993)
"The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing."3.68Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992)
"A case of early-onset sclerolimbal ectasia following low-dose topical mitomycin C application during uveitic glaucoma surgery is reported."1.33Early-onset scleral and corneal ectasias following low-dose mitomycin-C-augmented trabeculectomy in a uveitic glaucoma patient. ( Jockin, Y; O'Halloran, H; Pirouzian, A; Scher, C, 2006)
" Although topical mitomycin-C is effective as an adjunct to pterygium surgery and may reduce recurrence, the safety and efficacy of various concentrations and dosing schedules need further definition."1.29Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. ( Dougherty, PJ; Hardten, DR; Lindstrom, RL, 1996)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's9 (37.50)29.6817
2010's9 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prokosch-Willing, V1
Lamparter, J1
Ul Hassan, SN1
Toshev, AP1
Pfeiffer, N1
Hoffmann, EM1
Shin, HY1
Kim, MS1
Chung, SK1
Gupta, S2
Wadhwani, M1
Sehgal, V1
Sharma, S1
Dada, T1
Karioris, E1
Wirbelauer, C1
Häberle, H1
Pham, DT1
Jung, JW1
Kwon, KY1
Choi, DL1
Kim, TI1
Kim, EK1
Seo, KY2
Lindquist, TP1
Lee, WB1
García-Serrano, JL1
García-Robles, P1
Sánchez-Merino, C1
Rodríguez-Escobar, JJ1
Pinheiro-Chaves, A1
Kwon, HJ1
Nam, SM1
Lee, SY1
Ahn, JM1
Carrasco, MA1
Rapuano, CJ1
Cohen, EJ1
Laibson, PR1
Avisar, R1
Weinberger, D1
Eşme, A1
Yildirim, C1
Tatlipinar, S1
Düzcan, E1
Yaylali, V1
Ozden, S1
Sauder, G1
Jonas, JB1
Wan Norliza, WM1
Raihan, IS1
Azwa, JA1
Ibrahim, M1
Pirouzian, A1
O'Halloran, H1
Scher, C1
Jockin, Y1
Fujitani, A1
Hayasaka, S2
Shibuya, Y1
Noda, S1
Saifuddin, S1
el Zawawi, A1
Dougherty, PJ1
Hardten, DR1
Lindstrom, RL1
Hsiao, CH1
Chen, JJ1
Huang, SC1
Ma, HK1
Chen, PY1
Tsai, RJ1
Iwasa, Y1
Nagaki, Y1
Kadoi, C1
Matsumoto, M1
Hayasaka, Y1
Tsai, YY1
Lin, JM1
Shy, JD1
Safianik, B1
Ben-Zion, I1
Garzozi, HJ1
Basti, S1
Rubinfeld, RS1
Pfister, RR1
Stein, RM1
Foster, CS1
Martin, NF1
Stoleru, S1
Talley, AR1
Speaker, MG1

Reviews

1 review available for mitomycin and Sclera Diseases

ArticleYear
Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.
    Cornea, 2002, Volume: 21, Issue:2

    Topics: Acute Disease; Humans; Intraoperative Period; Lactose; Lubrication; Male; Methylcellulose; Middle Ag

2002

Trials

1 trial available for mitomycin and Sclera Diseases

ArticleYear
[Application of mitomycin in primary covered sclerotomy].
    Klinische Monatsblatter fur Augenheilkunde, 2014, Volume: 231, Issue:10

    Topics: Aged; Cataract Extraction; Female; Humans; Male; Minimally Invasive Surgical Procedures; Mitomycin;

2014

Other Studies

22 other studies available for mitomycin and Sclera Diseases

ArticleYear
Results of an Adaptive Surgical Approach for Managing Late Onset Hypotony After Trabeculectomy With Mitomycin C.
    Journal of glaucoma, 2018, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Blister; Combined Modality Therapy; Female; Glaucoma; Humans; Intrao

2018
The development of scleromalacia after regional conjunctivectomy with the postoperative application of mitomycin C as an adjuvant therapy.
    Korean journal of ophthalmology : KJO, 2013, Volume: 27, Issue:3

    Topics: Adult; Antibiotics, Antineoplastic; Conjunctival Diseases; Female; Humans; Mitomycin; Postoperative

2013
Blebitis with scleral abscess in a case of operated trabeculectomy with mitomycin C and a subcunjunctival ologen implant.
    Eye (London, England), 2014, Volume: 28, Issue:3

    Topics: Abscess; Alkylating Agents; Anti-Bacterial Agents; Ceftriaxone; Collagen; Drug Therapy, Combination;

2014
Long-term clinical outcomes of conjunctival flap surgery for calcified scleromalacia after periocular surgery.
    Cornea, 2015, Volume: 34, Issue:3

    Topics: Adult; Calcinosis; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Oph

2015
Mitomycin C-associated scleral stromalysis after pterygium surgery.
    Cornea, 2015, Volume: 34, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Chemotherapy, Adjuvant; Female; Humans; Male; Mid

2015
[Repair of a leaking bleb filtration with conjunctival and amniotic membrane transplantation].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:8

    Topics: Aged; Amnion; Conjunctiva; Female; Fibrin Tissue Adhesive; Humans; Lens Implantation, Intraocular; M

2011
Scleral melting secondary to surgical excision of a pterygium augmented with mitomycine C application.
    Bulletin de la Societe belge d'ophtalmologie, 2012, Issue:319

    Topics: Aged; Female; Humans; Mitomycin; Necrosis; Postoperative Complications; Pterygium; Sclera; Scleral D

2012
Conjunctival flap surgery for calcified scleromalacia after cosmetic conjunctivectomy.
    Cornea, 2013, Volume: 32, Issue:6

    Topics: Adult; Calcinosis; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Mitomycin; Ophthalmologic S

2013
Scleral ulceration after preoperative injection of mitomycin C in the pterygium head.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:11

    Topics: Alkylating Agents; Bacitracin; Humans; Injections, Intralesional; Male; Middle Aged; Mitomycin; Oint

2002
Pterygium surgery with mitomycin C: how much sclera should be left bare?
    Cornea, 2003, Volume: 22, Issue:8

    Topics: Administration, Topical; Adult; Conjunctiva; Drug Administration Schedule; Esthetics; Female; Humans

2003
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
    Strabismus, 2004, Volume: 12, Issue:3

    Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo

2004
Limbal stem cell deficiency after subconjunctival mitomycin C injection for trabeculectomy.
    American journal of ophthalmology, 2006, Volume: 141, Issue:6

    Topics: Antibiotics, Antineoplastic; Conjunctiva; Corneal Diseases; Humans; Injections; Limbus Corneae; Mito

2006
Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy.
    Contact lens & anterior eye : the journal of the British Contact Lens Association, 2006, Volume: 29, Issue:4

    Topics: Humans; Male; Middle Aged; Mitomycin; Nucleic Acid Synthesis Inhibitors; Ophthalmic Solutions; Ophth

2006
Early-onset scleral and corneal ectasias following low-dose mitomycin-C-augmented trabeculectomy in a uveitic glaucoma patient.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2006, Volume: 220, Issue:6

    Topics: Adolescent; Alkylating Agents; Combined Modality Therapy; Corneal Diseases; Dilatation, Pathologic;

2006
Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1993, Volume: 207, Issue:3

    Topics: Administration, Topical; Aged; Corneal Ulcer; Female; Humans; Mitomycin; Ophthalmic Solutions; Posto

1993
Scleral changes due to mitomycin C after pterygium excision: a report of two cases.
    Indian journal of ophthalmology, 1995, Volume: 43, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Calcinosis; Chemotherapy, Adjuvant; Humans; Male; Middle Aged; M

1995
Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C.
    Cornea, 1996, Volume: 15, Issue:5

    Topics: Chemotherapy, Adjuvant; Contraindications; Corneal Diseases; Eye Injuries, Penetrating; Humans; Intr

1996
Intrascleral dissemination of infectious scleritis following pterygium excision.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:1

    Topics: Abscess; Adult; Aged; Antibiotics, Antineoplastic; Eye Infections, Bacterial; Female; Follow-Up Stud

1998
Late complications after pterygium excision with high dose mitomycin C instillation.
    The British journal of ophthalmology, 2000, Volume: 84, Issue:9

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Female; Humans; Mitomycin; Postoperative Compl

2000
Serious corneoscleral complications after pterygium excision with mitomycin C.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Corneal Diseases; Humans; Male; Middle Aged; Mitomycin; Po

2002
Corneoscleral, ciliary body, and vitreoretinal toxicity after excessive instillation of mitomycin C.
    American journal of ophthalmology, 1992, Oct-15, Volume: 114, Issue:4

    Topics: Adult; Ciliary Body; Corneal Diseases; Eye Diseases; Female; Humans; Mitomycin; Pterygium; Retinal D

1992
Serious complications of topical mitomycin-C after pterygium surgery.
    Ophthalmology, 1992, Volume: 99, Issue:11

    Topics: Adult; Aged; Calcinosis; Cataract; Contraindications; Corneal Diseases; Eye Diseases; Female; Humans

1992