Page last updated: 2024-11-06

mitomycin and Sarcoma, Synovial

mitomycin has been researched along with Sarcoma, Synovial in 2 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Sarcoma, Synovial: A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)

Research Excerpts

ExcerptRelevanceReference
"In all 63 patients were treated monthly with a combination of mitomycin, doxorubicin, and cisplatin, and 27 (43%) experienced objective regression of their advanced sarcomas during a 3-month trial."7.67Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas. ( Creagan, ET; Edmonson, JH; Green, SJ; Long, HJ; Richardson, RL, 1985)
"In all 63 patients were treated monthly with a combination of mitomycin, doxorubicin, and cisplatin, and 27 (43%) experienced objective regression of their advanced sarcomas during a 3-month trial."3.67Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas. ( Creagan, ET; Edmonson, JH; Green, SJ; Long, HJ; Richardson, RL, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumgartner, JM1
Ahrendt, SA1
Pingpank, JF1
Holtzman, MP1
Ramalingam, L1
Jones, HL1
Zureikat, AH1
Zeh, HJ1
Bartlett, DL1
Choudry, HA1
Edmonson, JH1
Long, HJ1
Richardson, RL1
Creagan, ET1
Green, SJ1

Other Studies

2 other studies available for mitomycin and Sarcoma, Synovial

ArticleYear
Aggressive locoregional management of recurrent peritoneal sarcomatosis.
    Journal of surgical oncology, 2013, Volume: 107, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Chemo

2013
Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Dru

1985