Page last updated: 2024-11-06

mitomycin and Retinoblastoma

mitomycin has been researched along with Retinoblastoma in 3 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gibbons, B1
Scott, D1
Hungerford, JL1
Cheung, KL1
Harrison, C1
Attard-Montalto, S1
Evans, M1
Birch, JM1
Kingston, JE1
Woods, WG1
Byrne, TD1
Melaragno, MI1
Ribeiro, MC1
Smith, Mde A1
Andrade, JA1
Erwenne, CM1

Other Studies

3 other studies available for mitomycin and Retinoblastoma

ArticleYear
Retinoblastoma in association with the chromosome breakage syndromes Fanconi's anaemia and Bloom's syndrome: clinical and cytogenetic findings.
    Clinical genetics, 1995, Volume: 47, Issue:6

    Topics: Bloom Syndrome; Child, Preschool; Chromosome Aberrations; Chromosomes; DNA; Eye Neoplasms; Fanconi A

1995
In vitro sensitivity of normal and hereditary retinoblastoma fibroblasts to DNA-damaging agents.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Cells, Cultured; Dactinomycin; DNA; DNA Damage; DNA Repair; Eye Neoplasms; Fibroblasts; Gamma Rays;

1986
Sister chromatid exchange frequency in a retinoblastoma mosaic patient with del(13).
    Cancer genetics and cytogenetics, 1988, Volume: 32, Issue:2

    Topics: Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 13; Eye Neoplasms; Humans; Male; Mit

1988