Page last updated: 2024-11-06

mitomycin and Retinal Diseases

mitomycin has been researched along with Retinal Diseases in 22 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the clinical outcome of eyes which underwent primary trabeculectomy with adjunctive mitomycin C (MMC) for primary glaucoma."8.79Mitomycin C primary trabeculectomy in primary glaucoma of white patients. ( Nuijts, RM; Vernimmen, RC; Webers, CA, 1997)
"To evaluate the clinical outcome of eyes which underwent primary trabeculectomy with adjunctive mitomycin C (MMC) for primary glaucoma."4.79Mitomycin C primary trabeculectomy in primary glaucoma of white patients. ( Nuijts, RM; Vernimmen, RC; Webers, CA, 1997)
"02% mitomycin C (MMC) in glaucoma patients at risk for failure of filtration surgery."3.71Long term results and complications of trabeculectomy augmented with low dose mitomycin C in patients at risk for filtration failure. ( Casson, R; Rahman, R; Salmon, JF, 2001)
"After trabeculectomy with mitomycin C, extremely low intraocular pressure (IOP) with excess filtration may cause hypotonous maculopathy in the early postoperative period."3.71Autologous blood injection for marked overfiltration early after trabeculectomy with mitomycin C. ( Jian, K; Masumoto, M; Mishima, HK; Mochizuki, H; Okada, K; Okada, M; Tsukamoto, H, 2001)
"Hypotony maculopathy after glaucoma filtering surgery with adjunctive mitomycin C has been reported to occur in 3% to 14% of cases."3.69Hypotony maculopathy after filtering surgery with mitomycin C. Incidence and treatment. ( Greenfield, DS; Miller, MP; Nicolela, MT; Palmberg, PF; Suñer, IJ, 1997)
"This condition may manifest as multiple retinal hemorrhages, edema of the optic disc, macular edema, or a sudden decrease in visual acuity postoperatively."1.43Consecutive bilateral decompression retinopathy after mitomycin C trabeculectomy: a case report. ( Figueiredo, ARM; Menéres, MJFDS; Sampaio, IC; Spaeth, GL, 2016)
"A 71-year-old white woman with primary open angle glaucoma received trabeculectomy with antimetabolite."1.29Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite. ( Kaufman, PL; Kee, C, 1994)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (54.55)18.2507
2000's6 (27.27)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salinas, L1
Chaudhary, A1
Mansouri, K1
Figueiredo, ARM1
Sampaio, IC1
Menéres, MJFDS1
Spaeth, GL1
Juberías, JR1
Maquet, JA1
Ussa, F1
Macdonald, E1
Mukherjee, S1
Jay, J1
Goodkin, ML1
Grewal, DS1
Greenfield, DS2
Inoue, T1
Inatani, M1
Takihara, Y1
Awai-Kasaoka, N1
Ogata-Iwao, M1
Tanihara, H1
Westfall, AC1
Ng, JD1
Samples, JR1
Weissman, JL1
Oyakhire, JO1
Moroi, SE1
Suemori-Matsushita, H1
Okabe, I1
Yamamoto, T1
Hayakawa, T1
Kondo, Y1
Miyake, K1
Kitazawa, Y1
Duker, JS1
Schuman, JS1
Kee, C1
Kaufman, PL1
Nuyts, RM1
Greve, EL1
Geijssen, HC1
Langerhorst, CT1
Shields, MB1
Scroggs, MW1
Sloop, CM1
Simmons, RB1
Costa, VP1
Wilson, RP1
Moster, MR1
Schmidt, CM1
Gandham, S1
Suñer, IJ1
Miller, MP1
Nicolela, MT1
Palmberg, PF1
Lu, DW1
Azuara-Blanco, A1
Katz, LJ1
Nuijts, RM1
Vernimmen, RC1
Webers, CA1
Haynes, WL1
Alward, WL1
Casson, R1
Rahman, R1
Salmon, JF1
Okada, K1
Tsukamoto, H1
Masumoto, M1
Jian, K1
Okada, M1
Mochizuki, H1
Mishima, HK1
Gupta, S1
Basti, S1
Jampel, HD1
Pasquale, LR1
Dibernardo, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Modified Trabeculectomy With an Extended Subscleral Tunnel Versus Conventional Trabeculectomy for Management of Primary Open Angle Glaucoma (POAG)[NCT03480711]40 participants (Actual)Interventional2018-07-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mitomycin and Retinal Diseases

ArticleYear
Mitomycin C primary trabeculectomy in primary glaucoma of white patients.
    Journal of glaucoma, 1997, Volume: 6, Issue:5

    Topics: Antimetabolites; Cataract; Disease Progression; Glaucoma; Humans; Intraocular Pressure; Intraoperati

1997

Other Studies

21 other studies available for mitomycin and Retinal Diseases

ArticleYear
Optical Coherence Tomography Angiography Description of Ocular Decompression Retinopathy After Deep Sclerectomy in Traumatic Glaucoma.
    Journal of glaucoma, 2018, Volume: 27, Issue:3

    Topics: Alkylating Agents; Decompression, Surgical; Eye Injuries; Fluorescein Angiography; Glaucoma, Open-An

2018
Consecutive bilateral decompression retinopathy after mitomycin C trabeculectomy: a case report.
    Journal of medical case reports, 2016, Feb-04, Volume: 10

    Topics: Cross-Linking Reagents; Decompression; Female; Glaucoma, Open-Angle; Humans; Middle Aged; Mitomycin;

2016
[Decompression retinopathy with maculopathy after trabeculectomy with mitomycin C].
    Archivos de la Sociedad Espanola de Oftalmologia, 2008, Volume: 83, Issue:6

    Topics: Adult; Humans; Macular Edema; Male; Mitomycin; Papilledema; Retinal Diseases; Retinal Hemorrhage; Tr

2008
The increasingly iatrogenic indications for mitomycin C trabeculectomy over 10 years.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:2

    Topics: Alkylating Agents; Combined Modality Therapy; Corneal Transplantation; Female; Glaucoma; Humans; Iat

2009
Three-dimensional high-speed optical coherence tomography for diagnosis of hypotony maculopathy after glaucoma filtration surgery.
    Journal of glaucoma, 2010, Volume: 19, Issue:6

    Topics: Aged; Alkylating Agents; Female; Glaucoma; Humans; Imaging, Three-Dimensional; Intraocular Pressure;

2010
Prognostic risk factors for failure of trabeculectomy with mitomycin C after vitrectomy.
    Japanese journal of ophthalmology, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Female; Glaucoma; Huma

2012
Hypotonus maculopathy: magnetic resonance appearance.
    American journal of ophthalmology, 2004, Volume: 137, Issue:3

    Topics: Choroid Diseases; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Macula Lutea; Magnetic Resonan

2004
Clinical and anatomical reversal of long-term hypotony maculopathy.
    American journal of ophthalmology, 2004, Volume: 137, Issue:5

    Topics: Antibiotics, Antineoplastic; Conjunctiva; Female; Glaucoma; Humans; Intraocular Pressure; Middle Age

2004
[Hypotonous maculopathy following trabeculectomy with mitomycin C].
    Nippon Ganka Gakkai zasshi, 1995, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Incidence; Intraocular Pressure; Macula

1995
Successful surgical treatment of hypotony maculopathy following trabeculectomy with topical mitomycin C.
    Ophthalmic surgery, 1994, Volume: 25, Issue:7

    Topics: Administration, Topical; Adult; Glaucoma; Humans; Intraocular Pressure; Macula Lutea; Male; Mitomyci

1994
Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite.
    Acta ophthalmologica, 1994, Volume: 72, Issue:3

    Topics: Aged; Female; Fluorescein Angiography; Fluorouracil; Fundus Oculi; Glaucoma, Open-Angle; Humans; Int

1994
Treatment of hypotonous maculopathy after trabeculectomy with mitomycin C.
    American journal of ophthalmology, 1994, Sep-15, Volume: 118, Issue:3

    Topics: Adult; Aged; Blood Transfusion, Autologous; Contact Lenses; Female; Humans; Intraocular Pressure; Ma

1994
Clinical and histopathologic observations concerning hypotony after trabeculectomy with adjunctive mitomycin C.
    American journal of ophthalmology, 1993, Dec-15, Volume: 116, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Conjunctiva; Female; Fibrosis

1993
Hypotony maculopathy following the use of topical mitomycin C in glaucoma filtration surgery.
    Ophthalmic surgery, 1993, Volume: 24, Issue:6

    Topics: Administration, Topical; Adult; Aged; Cryosurgery; Female; Glaucoma, Open-Angle; Humans; Macula Lute

1993
Hypotony maculopathy after filtering surgery with mitomycin C. Incidence and treatment.
    Ophthalmology, 1997, Volume: 104, Issue:2

    Topics: Adult; Aged; Cataract Extraction; Chemotherapy, Adjuvant; Cornea; Female; Filtering Surgery; Follow-

1997
Severe visual loss after autologous blood injection for mitomycin-C-associated hypotonous maculopathy.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:3

    Topics: Adult; Blood; Glaucoma, Open-Angle; Humans; Injections; Intraocular Pressure; Macula Lutea; Male; Mi

1997
Combination of autologous blood injection and bleb compression sutures to treat hypotony maculopathy.
    Journal of glaucoma, 1999, Volume: 8, Issue:6

    Topics: Aged; Aged, 80 and over; Alkylating Agents; Blood; Combined Modality Therapy; Female; Glaucoma; Huma

1999
Long term results and complications of trabeculectomy augmented with low dose mitomycin C in patients at risk for filtration failure.
    The British journal of ophthalmology, 2001, Volume: 85, Issue:6

    Topics: Aged; Cataract; Female; Glaucoma; Humans; Intraocular Pressure; Macula Lutea; Male; Middle Aged; Mit

2001
Autologous blood injection for marked overfiltration early after trabeculectomy with mitomycin C.
    Acta ophthalmologica Scandinavica, 2001, Volume: 79, Issue:3

    Topics: Aged; Aged, 80 and over; Aqueous Humor; Blood; Female; Glaucoma, Open-Angle; Humans; Injections; Int

2001
Corneoscleral, ciliary body, and vitreoretinal toxicity after excessive instillation of mitomycin C.
    American journal of ophthalmology, 1992, Oct-15, Volume: 114, Issue:4

    Topics: Adult; Ciliary Body; Corneal Diseases; Eye Diseases; Female; Humans; Mitomycin; Pterygium; Retinal D

1992
Hypotony maculopathy following trabeculectomy with mitomycin C.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:8

    Topics: Adult; Fundus Oculi; Humans; Intraocular Pressure; Macula Lutea; Male; Mitomycin; Postoperative Comp

1992