mitomycin has been researched along with Retinal Detachment in 10 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the anatomic and visual outcomes of a new intraocular mitomycin c (MMC) application technique in the treatment of severe traumatic retinal detachment (RD) with advance proliferative vitreoretinopathy (PVR)." | 8.02 | Intraocular mitomycin C use in the treatment and prophylaxis of proliferative vitreoretinopathy in severe traumatic retinal detachments. ( Gürelik, G; Sül, S; Üçgül, AY, 2021) |
| "To evaluate the anatomic and visual outcomes of a new intraocular mitomycin c (MMC) application technique in the treatment of severe traumatic retinal detachment (RD) with advance proliferative vitreoretinopathy (PVR)." | 4.02 | Intraocular mitomycin C use in the treatment and prophylaxis of proliferative vitreoretinopathy in severe traumatic retinal detachments. ( Gürelik, G; Sül, S; Üçgül, AY, 2021) |
| " Procedures for the control of glaucoma were silicone oil removal (SOR), trabeculectomy with mitomycin C, cyclocryotherapy, semiconductor diode laser contact transscleral cyclophotocoagulation (TSCPC) and anterior chamber tube shunt to encircling band (ACTSEB)." | 3.70 | Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments. ( Dandona, L; Goyal, M; Honavar, SG; Majji, AB; Naduvilath, T; Sen, PK, 1999) |
| "A pars plana vitrectomy was performed in 12 eyes, and two neurosensory retinal detachments per eye were created by injecting 10(-3) mg/ml mitomycin C and 0." | 3.69 | Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration. ( Del Priore, LV; Hornbeck, R; Jones, Z; Kaplan, HJ; Swinn, M, 1996) |
| "To present a rare presentation of pyogenic granuloma arising almost 4 decades after a scleral buckle for retinal detachment." | 1.62 | Silk Suture Granuloma 37 Years After Scleral Buckle Surgery: A Case Report. ( Cabot, F; Dubovy, S; Galor, A; Karp, CL; Patel, U; Theotoka, D; Wall, S; Zein, M, 2021) |
| "We report a case of suprachoroidal hemorrhage following removal of a releasable suture after combined phacoemulsification-trabeculectomy." | 1.34 | Suprachoroidal hemorrhage following removal of releasable suture after combined phacoemulsification-trabeculectomy. ( Eong, KG; Prashanth, S; Raman, GV; Sathyan, P; Singh, G, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zein, M | 1 |
| Theotoka, D | 1 |
| Wall, S | 1 |
| Galor, A | 1 |
| Cabot, F | 1 |
| Patel, U | 1 |
| Dubovy, S | 1 |
| Karp, CL | 1 |
| Lo, WJ | 1 |
| Kuang, TM | 1 |
| Chen, SJ | 1 |
| Hwang, DK | 1 |
| Gürelik, G | 1 |
| Sül, S | 1 |
| Üçgül, AY | 1 |
| Smith, M | 1 |
| Mavrikakis, E | 1 |
| Buys, YM | 1 |
| Takihara, Y | 1 |
| Inatani, M | 1 |
| Fukushima, M | 1 |
| Iwao, K | 1 |
| Iwao, M | 1 |
| Tanihara, H | 1 |
| Sathyan, P | 2 |
| Singh, G | 1 |
| Eong, KG | 1 |
| Raman, GV | 1 |
| Prashanth, S | 1 |
| Al-Harthi, E | 1 |
| Al-Shahwan, S | 1 |
| Al-Turkmani, S | 1 |
| Khan, AO | 1 |
| Kersten, RC | 1 |
| Kulwin, DR | 1 |
| Del Priore, LV | 1 |
| Kaplan, HJ | 1 |
| Hornbeck, R | 1 |
| Jones, Z | 1 |
| Swinn, M | 1 |
| Honavar, SG | 1 |
| Goyal, M | 1 |
| Majji, AB | 1 |
| Sen, PK | 1 |
| Naduvilath, T | 1 |
| Dandona, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy[NCT01255306] | 60 participants (Actual) | Observational | 2010-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Retinal nerve fiber layer thickness change measured by optical coherence tomography might be an additional parameter that could provide new insights into clinical decision making in patients with silicone oil tamponade. (NCT01255306)
Timeframe: 6 months
| Intervention | micrometer (Mean) | |||
|---|---|---|---|---|
| RNFL thickness at 7th postop. day | RNFL thickness at 30th postop. day | RNFL thickness at 90th postop. day | RNFL thickness at 180th postop. day | |
| CONTROL EYES | 87.07 | 87.93 | 87.37 | 88.93 |
| STUDY EYES | 96.23 | 96.09 | 97.56 | 100.40 |
To assess whether retinal nerve fiber layer thickness changes in patients with raised intraocular pressure secondary to silicone oil endotamponade. (NCT01255306)
Timeframe: 6 months
| Intervention | micrometer (Mean) | |||
|---|---|---|---|---|
| RNFL thickness at 7th postop. day | RNFL thickness at 30th postop. day | RNFL thickness at 90th postop. day | RNFL thickness at 180th postop. day | |
| CONTROL | 87.07 | 87.93 | 87.37 | 88.93 |
| NO IOP | 96.08 | 93.76 | 96.44 | 101.76 |
| RAISED IOP | 96.34 | 97.91 | 98.44 | 99.34 |
10 other studies available for mitomycin and Retinal Detachment
| Article | Year |
|---|---|
Silk Suture Granuloma 37 Years After Scleral Buckle Surgery: A Case Report.
Topics: Antibiotics, Antineoplastic; Cryotherapy; Granuloma, Pyogenic; Humans; Male; Middle Aged; Mitomycin; | 2021 |
Acute Necrotizing Retinopathy After Xen Gel Stent Implantation.
Topics: Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; | 2023 |
Intraocular mitomycin C use in the treatment and prophylaxis of proliferative vitreoretinopathy in severe traumatic retinal detachments.
Topics: Follow-Up Studies; Humans; Mitomycin; Retina; Retinal Detachment; Retrospective Studies; Silicone Oi | 2021 |
Postvitrectomy posturing resulting in contralateral ocular hypotony.
Topics: Aged; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Mitomycin; Ocular Hypotension; Pos | 2008 |
Trabeculectomy with mitomycin C for neovascular glaucoma: prognostic factors for surgical failure.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Female; F | 2009 |
Suprachoroidal hemorrhage following removal of releasable suture after combined phacoemulsification-trabeculectomy.
Topics: Aged; Alkylating Agents; Cataract; Choroid Hemorrhage; Combined Modality Therapy; Exfoliation Syndro | 2007 |
Retinal detachment and congenital glaucoma.
Topics: Combined Modality Therapy; Female; Humans; Hydrophthalmos; Intraocular Pressure; Male; Mitomycin; Po | 2007 |
MMC in ONS decompression.
Topics: Adolescent; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Humans; Male; Mitomycin; Myelin S | 1996 |
Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration.
Topics: Animals; Atrophy; Bruch Membrane; Capillaries; Cell Division; Choroid; Debridement; Disease Models, | 1996 |
Glaucoma after pars plana vitrectomy and silicone oil injection for complicated retinal detachments.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Ciliary Body; Cryotherapy; Female; Follow-Up Stud | 1999 |