mitomycin has been researched along with Purpura, Thrombocytopenic, Idiopathic in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-(2-Pyridylsulfonyl)-2-thiazolamine (2) was effective both in mitomycin C (MMC)-induced thrombocytopenia and in an animal model of idiopathic thrombocytopenic purpura (ITP)." | 3.70 | Synthesis and effects of novel thiazole derivatives against thrombocytopenia. ( Manda, T; Matsuo, M; Nishigaki, F; Ogino, T; Sawada, M; Seki, N; Sudo, Y; Tsuji, K, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuji, K | 1 |
| Ogino, T | 1 |
| Seki, N | 1 |
| Sawada, M | 1 |
| Sudo, Y | 1 |
| Nishigaki, F | 2 |
| Manda, T | 2 |
| Matsuo, M | 1 |
| Tsujimoto, S | 1 |
| Inami, M | 1 |
| Matsumoto, S | 1 |
| Naoe, Y | 1 |
| Kawamura, I | 1 |
| Shimomura, K | 1 |
2 other studies available for mitomycin and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Synthesis and effects of novel thiazole derivatives against thrombocytopenia.
Topics: Animals; Autoantibodies; Blood Platelets; Dapsone; Disease Models, Animal; Dose-Response Relationshi | 1998 |
Effects of a novel pyridylsulphonyl thiazole derivative, FR115092, on autoimmune and mitomycin C-induced thrombocytopenia in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Autoimmunity; Blood Platelets; Bon | 1999 |