mitomycin has been researched along with Pulmonary Fibrosis in 16 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome." | 7.67 | Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986) |
| "After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome." | 3.67 | Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986) |
| "Thirty-three patients with advanced cervical cancer (31 squamous cancer, two adenosquamous cancer) previously untreated with cytotoxic drugs, were treated with bleomycin, 5 mg daily, for seven days and mitomycin C, 10 mg, on day 8." | 1.27 | Bleomycin-mitomycin C in advanced carcinoma of the cervix. A third look. ( Gullberg, B; Johnsson, JE; Mattsson, W; Sigurdsson, K; Simonsen, E; Stendahl, U; Tropé, C, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zappa, L | 1 |
| Savady, R | 1 |
| Humphries, GN | 1 |
| Sugarbaker, PH | 1 |
| Ginsberg, SJ | 1 |
| Comis, RL | 1 |
| Tropé, C | 1 |
| Johnsson, JE | 1 |
| Simonsen, E | 1 |
| Sigurdsson, K | 1 |
| Stendahl, U | 1 |
| Mattsson, W | 1 |
| Gullberg, B | 1 |
| Cohen, MH | 1 |
| Matthews, MJ | 1 |
| Boven, E | 1 |
| Pinedo, HM | 2 |
| van Spreeuwel, JP | 1 |
| Hemrika, MH | 1 |
| de Maat, CE | 1 |
| Nadorp, JH | 1 |
| Lenci, G | 1 |
| Müller-Quernheim, J | 1 |
| Lorenz, J | 1 |
| Schweden, F | 1 |
| Ferlinz, R | 1 |
| Thompson, CC | 1 |
| Bailey, MK | 1 |
| Conroy, JM | 1 |
| Bromley, HR | 1 |
| Gatzemeier, U | 1 |
| Fasske, E | 1 |
| Nowak, U | 1 |
| Koga, K | 1 |
| Minoda, S | 1 |
| Majeski, JA | 1 |
| Stinnett, JD | 1 |
| Cameron, DJ | 1 |
| McCarthy, JT | 1 |
| Staats, BA | 1 |
| Neubauer, H | 1 |
| Blech, M | 1 |
| Wilhelms, E | 1 |
| Crieé, CP | 1 |
| Neuhaus, KL | 1 |
| Truss, F | 1 |
| Verweij, J | 1 |
| van Zanten, T | 1 |
| Souren, T | 1 |
| Golding, R | 1 |
| Sagawa, M | 1 |
| Takahashi, S | 1 |
| Usuda, K | 1 |
| Kamma, K | 1 |
| Satoh, M | 1 |
| Ohta, S | 1 |
| Nagamoto, N | 1 |
| Imai, T | 1 |
| Saitoh, Y | 1 |
| Suda, H | 1 |
1 review available for mitomycin and Pulmonary Fibrosis
| Article | Year |
|---|---|
Prospective study on the dose relationship of mitomycin C-induced interstitial pneumonitis.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Mitomycin; Mitomyc | 1987 |
1 trial available for mitomycin and Pulmonary Fibrosis
| Article | Year |
|---|---|
[Experimental and clinical data of the pulmonary toxicity of mitomycin C].
Topics: Animals; Endothelium, Vascular; Humans; Lung; Mice; Mitomycin; Mitomycins; Prospective Studies; Pulm | 1990 |
14 other studies available for mitomycin and Pulmonary Fibrosis
| Article | Year |
|---|---|
Interstitial pneumonitis following intrapleural chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Fatal Outcom | 2009 |
The pulmonary toxicity of antineoplastic agents.
Topics: Age Factors; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bleomycin; Busul | 1982 |
Bleomycin-mitomycin C in advanced carcinoma of the cervix. A third look.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combina | 1983 |
Chemotherapy-induced pulmonary toxicity in mice bearing L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Doxorubicin; Leukemia L1210; Lung Dise | 1983 |
Mitomycin C: interstitial pneumonitis and haemolytic-uraemic syndrome.
Topics: Adult; Female; Hemolytic-Uremic Syndrome; Humans; Mitomycin; Mitomycins; Prednisone; Pulmonary Fibro | 1983 |
Two patients suffering from interstitial pneumonitis and haemolytic-uraemic syndrome as side effects of mitomycin C therapy.
Topics: Adult; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Pulmonary Fibros | 1983 |
[Toxic lung damage caused by mitomycin C].
Topics: Aged; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Human | 1994 |
Postoperative pulmonary toxicity associated with mitomycin-C therapy.
Topics: Adult; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Humans; Lung Neoplasms; Male; Mito | 1992 |
[Interstitial pneumonia developed after combination chemotherapy with (CDDP, VDS, MMC) and radiotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Mod | 1990 |
Suppressor T cell activity in lymphoid interstitial pneumonia.
Topics: Female; Fluorescent Antibody Technique; Humans; Levamisole; Lymphocyte Activation; Middle Aged; Mito | 1987 |
Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome.
Topics: Adenocarcinoma; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colonic N | 1986 |
[Lung injury following mitomycin C].
Topics: Humans; Lung; Mitomycin; Mitomycins; Pulmonary Fibrosis | 1987 |
[Pulmonary fibrosis following instillation of mitomycin C in the urinary bladder].
Topics: Administration, Intravesical; Adult; Carcinoma, Transitional Cell; Humans; Male; Mitomycin; Mitomyci | 1987 |
[Interstitial pneumonia after CMC (CDDP, MMC, CPM) therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined | 1988 |