mitomycin has been researched along with Pterygium in 229 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Pterygium: An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the influence of preoperative mitomycin C (MMC) on the proliferative behavior of fibroblasts and fibrovascular tissue derived from the primary pterygium using the immunohistochemical method (Ki67 and CD34)." | 9.30 | Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial. ( Alves, MR; Chammas, R; de Azevedo Costa, ALF; Dos Santos Martins, TG; Furuzawa, KM, 2019) |
| "To investigate the effect of pterygium morphology on recurrence with preoperative subconjunctival injection of mitomycin-C in primary pterygium surgery." | 9.30 | Effect of Pterygium Morphology on Recurrence with Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery. ( Khan, FA; Niazi, SPK, 2019) |
| "To evaluate and compare the recurrence rate and complications of conjunctival autograft (CAG) combined with preoperative mitomycin C (MMC) injection versus CAG with intraoperative local MMC over the medial rectus muscle tendon in primary pterygium." | 9.27 | Conjunctival Autograft Combined With Either Preoperative Mitomycin C Injection or Intraoperative Local Mitomycin C Over the Medial Rectus Muscle Tendon in Primary Pterygium Surgery. ( Abdelrahman, A; Abdulhalim, BH; Gad, AAM; Lotfy, A; Samir, A, 2018) |
| "02 % mitomycin C (MMC) to treat recurrent pterygium." | 9.24 | Limbal conjunctival versus amniotic membrane in the intraoperative application of mitomycin C for recurrent pterygium: a randomized controlled trial. ( Chen, R; Huang, G; Liu, S; Ma, W; Yin, X; Zhou, S, 2017) |
| "To compare the effectiveness of preoperative subconjunctival injection of Mitomycin-C at 24-hour and at one month before primary pterygium excision." | 9.24 | Effectiveness of Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery. ( Akhter, N; Awais, M; Ishaq, M; Khan, FA; Niazi, ShP, 2017) |
| "To compare the results of amniotic membrane transplantation (AMT) combined with mitomycin C (MMC) to the results of free conjunctival autograft (CA) combined with MMC for the treatment of patients with recurrent pterygium." | 9.20 | Comparison of Two Techniques for the Treatment of Recurrent Pterygium: Amniotic Membrane vs Conjunctival Autograft Combined with Mitomycin C. ( Altiparmak, U; Cakir, B; Engur Goktas, S; Katırcıoglu, YA; Ornek, F; Singar, E, 2015) |
| "To compare the recurrence rates and complications associated with instillation of topical mitomycin C, cyclosporine, and bevacizumab after primary pterygium surgery." | 9.20 | A Comparative Study of Topical Mitomycin C, Cyclosporine, and Bevacizumab after Primary Pterygium Surgery. ( Choi, S; Hwang, S, 2015) |
| "To compare the long-term outcome of pterygium surgery and the long-term effect on endothelial counts after mitomycin C (MMC) or limbal conjunctival autograft (LCAU) in pterygium surgery." | 9.17 | Ten-year results of a randomized controlled trial comparing 0.02% mitomycin C and limbal conjunctival autograft in pterygium surgery. ( Cheng, LL; Ho, M; Jhanji, V; Young, AL, 2013) |
| "To compare the 4-year outcome of primary pterygium excision using intraoperative mitomycin C (MMC) with suturing a free conjunctival autograft (CA)." | 9.16 | Intraoperative mitomycin C versus autologous conjunctival autograft in surgery of primary pterygium with four-year follow-up. ( Artzén, D; Kopp, ED; Koranyi, G; Seregard, S, 2012) |
| "To compare the outcomes of free conjunctival autograft (CAU) versus conjunctival-limbal autograft (CLAU) in the prevention of recurrence after pterygium surgery with adjunctive mitomycin C application in patients with primary or recurrent pterygia." | 9.16 | Randomized trial of pterygium surgery with mitomycin C application using conjunctival autograft versus conjunctival-limbal autograft. ( Adelpour, M; Behrouz, MJ; Hashemi, H; Kheirkhah, A; Nikdel, M; Rajabi, MB, 2012) |
| "To compare the efficacy of 5-fluorouracil (5-FU) with mitomycin C (MMC) in preventing pterygium recurrence when used as an adjuvant following pterygium excision with conjunctival autograft." | 9.16 | 5-Fluorouracil versus mitomycin C as adjuncts to conjunctival autograft in preventing pterygium recurrence. ( Ashaye, A; Baiyeroju, A; Bekibele, CO; Fasina, O; Ibrahim, AO; Ogun, O; Olusanya, B, 2012) |
| "To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium." | 9.16 | Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery. ( Khalifa, YM; Zaky, KS, 2012) |
| "To evaluate changes in corneal endothelial cell counts after pterygium surgery with application of mitomycin C (MMC) either on the perilimbal sclera or in the subconjunctival space." | 9.15 | Effects of mitomycin C on corneal endothelial cell counts in pterygium surgery: role of application location. ( Behrouz, MJ; Hashemian, H; Izadi, A; Kheirkhah, A; Kiarudi, MY; Nazari, R, 2011) |
| "To evaluate postoperative outcome and recurrence rate after primary pterygium excision using preoperative Mitomycin C (MMC) injection versus limbal conjunctival autograft transplantation (LCAT)." | 9.15 | Preoperative subpterygial mitomycin C injection versus limbal conjunctival autograft transplantation for prevention of pterygium recurrence. ( Farahat, HG; Mandour, SS; Mohamed, HM, 2011) |
| "To evaluate and compare the recurrence rates and complications between 2 therapeutic methods for primary pterygium: subconjunctival injection of mitomycin C (MMC) 1 month before bare scleral excision and conjunctival rotational flap with intraoperative MMC use." | 9.14 | Preoperative subpterygeal injection vs intraoperative mitomycin C for pterygium removal: comparison of results and complications. ( Daneshvar, R; Ghate, MF; Ghooshkhanehi, H; Khakshoor, H; Razavi, ME; Shakeri, MT, 2010) |
| "To compare the efficacy and complications of conjunctival limbal autograft (CLAU) and amniotic membrane transplantation (AMT) vsintraoperative mitomycin C (MMC) and AMT for treatment of recurrent pterygium." | 9.13 | Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium. ( Amozadeh, J; Fakhraee, G; Fallah, MR; Golabdar, MR; Moghimi, S; Zare, MA, 2008) |
| "To compare the clinical outcome of pterygium surgery combining intraoperative mitomycin C (MMC) with a free conjunctival autograft, with three other methods of pterygium surgery, including intraoperative MMC alone, conjunctival autograft alone, and bare sclera without adjunctive treatment." | 9.12 | Conjunctival autografting combined with low-dose mitomycin C for prevention of primary pterygium recurrence. ( Frucht-Pery, J; Ilsar, M; Landau, D; Orucov, F; Raiskup, F; Solomon, A, 2006) |
| "To evaluate the safety and efficacy of a preoperative injection of mitomycin C (MMC) in combined pterygium and cataract surgery." | 9.11 | Preoperative injection of mitomycin C in combined pterygium and cataract surgery. ( Avisar, R; Bar, S; Weinberger, D, 2005) |
| "To determine if a pterygium surgical procedure consisting of minimal conjunctival removal, excision of the hypertrophic subconjunctival fibrovascular tissue, application of mitomycin 0." | 9.11 | Pterygium surgery with mitomycin and tarsorrhaphy. ( Hamilton, DL; Williams, BL; Williams, EE; Wood, TO, 2005) |
| "02% mitomycin C is safe and more effective than a 3-minute application in recurrence of pterygium." | 9.10 | Intraoperative mitomycin C 0.02% for pterygium: effect of duration of application on recurrence rate. ( Appel, I; Avisar, R; Gaton, DD; Loya, N; Weinberger, D, 2003) |
| "To evaluate the safety and efficacy of single-drop instillation of mitomycin C (MMC) in pterygium surgery and to compare the results with both postoperative and intraoperative application of MMC." | 9.10 | Comparison of single-drop mitomycin C regime with other mitomycin C regimes in pterygium surgery. ( Gupta, VP; Saxena, T, 2003) |
| "To explore the feasibility of intraoperative application of mitomycin C (MMC) in pterygium and observe the ultrastructure change of pterygium with or without intraoperative application of MMC." | 9.09 | [Study of intraoperative mitomycin C in preventing recurrence after pterygium surgery]. ( Jiang, YQ; Mo, XJ; Xie, Q, 2001) |
| "Limbal conjunctival autograft transplantation or low-dose intraoperative mitomycin C application with conjunctival flap technique was performed on recurrent pterygium cases." | 9.09 | A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap. ( Mutlu, FM; Sobaci, G; Tatar, T; Yildirim, E, 1999) |
| "To evaluate the effectiveness of intraoperative mitomycin C in preventing the recurrence of primary pterygium." | 9.09 | Intraoperative mitomycin C in the treatment of pterygium. ( Alp, BN; Ay, GM; Caglar, Y; Karabas, L; Talu, H; Yanyali, AC, 2000) |
| "To evaluate the efficacy and safety of low-dose intraoperative mitomycin C (MMC) during bare sclera procedure and to compare the rates of pterygium recurrence between recurrent pterygium patients treated with adjuvant MMC and those reconstructed with a conjunctival autograft." | 9.09 | Low-dose intraoperative mitomycin C as chemoadjuvant for pterygium surgery. ( Chen, FK; Cheng, HC; Kao, PL; Tseng, SH, 2001) |
| "A prospective, randomised, double blind, placebo controlled study of intraoperative mitomycin C as adjunctive treatment of primary pterygium was conducted." | 9.08 | Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium. ( Cano-Parra, J; Diaz-Llopis, M; Maldonado, MJ; Menezo, JL; Vila, E, 1995) |
| "02% mitomycin C is an effective treatment for prevention of recurrence of pterygium." | 9.08 | Intraoperative application of topical mitomycin C for pterygium surgery. ( Frucht-Pery, J; Ilsar, M; Siganos, CS, 1996) |
| "The study was designed to evaluate the long term results of intraoperative mitomycin C in patients with one recurrence of pterygium." | 9.08 | Long term results of intraoperative mitomycin C in the treatment of recurrent pterygium. ( Carpineto, P; Ciancaglini, M; Enrico Gallenga, P; Mastropasqua, L, 1996) |
| "In this clinical trial the recurrence-rate after primary pterygium-excision, phototherapeutic keratectomy with the ArF:excimerlaser and local application of mitomycin C should be estimated." | 9.08 | [Incidence of recurrence after primary pterygium excision, phototherapeutic keratectomy with the ArF:Excimer laser and local mitomycin C administration]. ( Anders, N; Antoni, HJ; Walkow, T; Wollensak, J, 1996) |
| "to investigate, in the first report in Central Africa, the influence of tropical Mitomycin C on the recurrence rate and on the complications after surgical treatment for primary pterygium." | 9.08 | Postoperative instillation of 0.04% mitomycin C in the treatment of primary pterygium in Zaire. ( Kaimbo Wa Kaimbo, D, 1996) |
| "To determine the minimum effective dosage, most effective route of administration and long-term effects of mitomycin C for prevention of recurrence after pterygium surgery." | 9.08 | Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. ( Alves, MR; Ambrosio, LE; Cardillo, JA; Jose, NK; Poterio, MB, 1995) |
| "Conjunctival autograft transplantation and postoperative mitomycin therapy are two adjuvant treatment methods shown to lessen the high pterygium recurrence rate seen with simple excision alone." | 9.08 | Intraoperative mitomycin in primary pterygium excision. A prospective, randomized trial. ( Diaz, MD; Kloess, PM; Manning, CA; Yee, RW, 1997) |
| "04% mitomycin-C, either postoperatively for 2 weeks or intraoperatively as a single dose, as an adjunct in the surgical treatment of primary pterygium was evaluated." | 9.08 | Intraoperative and postoperative use of mitomycin-C in the treatment of primary pterygium. ( Calişkan, S; Irkeç, M; Orhan, M, 1996) |
| "02 mg/ml, with an accurate size of sterile sponge applied to bare sclera after primary pterygium excision decreases the rate of recurrence to a greater extent than does gentamicin solution and is not associated with severe complications." | 9.08 | Randomized trial of intraoperative mitomycin C in surgery for pterygium. ( Das, GK; Kumar, A; Panda, A; Tuli, SW, 1998) |
| "A prospective study was carried out to assess the recurrence rate of pterygium with conjunctival autograft versus the use of topical mitomycin C." | 9.08 | Conjunctival autograft versus topical mitomycin C in treatment of pterygium. ( Mahar, PS, 1997) |
| "The purpose of the study was to examine the efficacy of intraoperative mitomycin C (MMC) in preventing recurrence of pterygium after excision and the postoperative complications encountered." | 9.08 | Intraoperative mitomycin C to prevent recurrence of pterygium after excision: a 30-month follow-up study. ( Chew, S; Fan, DS; Kwok, PS; Lam, DS; Tso, MO; Wong, AK, 1998) |
| "A surgical technique was designed to improve safety after pterygium excision with intraoperative application of mitomycin-C (MMC)." | 9.08 | An improved surgical technique for pterygium excision with intraoperative application of mitomycin-C. ( Alves, MR; Cardillo, JA; José, NK; Potério, MB, 1998) |
| " Topical Mitomycin caused: iritis, conjunctival irritation, excessive lacrymation, photophobia, ocular pain; Thio-tepa caused: photophobia, foreign body sensation, headache." | 9.08 | [A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results]. ( Kayembe, L; Ngoy, D, 1998) |
| "The effectiveness of intraoperative administration of mitomycin C and the occurrence of postoperative complications have been evaluated in 30 white patients with one recurrence of pterygium." | 9.07 | Effectiveness of intraoperative mitomycin C in the treatment of recurrent pterygium. ( Carpineto, P; Ciancaglini, M; Gallenga, PE; Lobefalo, L; Mastropasqua, L, 1994) |
| "We studied the recurrence rate of pterygium after administration of a single dosage of topical mitomycin C at the completion of pterygium surgery." | 9.07 | Single dosage of mitomycin C for prevention of recurrent pterygium: preliminary report. ( Frucht-Pery, J; Hemo, I; Ilsar, M, 1994) |
| "The administration of high doses of topical mitomycin C after pterygium excision causes a variety of complications." | 9.07 | The use of low-dose mitomycin C for prevention of recurrent pterygium. ( Frucht-Pery, J; Ilsar, M, 1994) |
| "To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C." | 8.81 | Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002) |
| "Bare sclera resection with and without use of mitomycin C and conjunctival autograft placement are three surgical techniques currently in use for the treatment of primary pterygium." | 8.80 | Meta-analysis on the recurrence rates after bare sclera resection with and without mitomycin C use and conjunctival autograft placement in surgery for primary pterygium. ( Rocha, G; Sánchez-Thorin, JC; Yelin, JB, 1998) |
| "To report on the outcomes of recurrent pterygium treated by ipsilateral simple limbal epithelial transplantation (SLET), mitomycin, tenonectomy, and amniotic membrane transplantation." | 8.02 | Outcomes of Ipsilateral Simple Limbal Epithelial Transplantation, Tenonectomy, Mitomycin and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium. ( Cohen, E; Einan-Lifshitz, A; Mednick, Z; Mimouni, M; Santaella, G; Slomovic, A; Sorkin, N; Trinh, T, 2021) |
| "To investigate the antifibrotic effects of sakuraso-saponin on a primary culture of human pterygium fibroblasts (HPFs) and normal human Tenon fibroblasts (HTFs) as compared to the effects of mitomycin C (MMC)." | 7.91 | Antifibrotic Effects of Sakuraso-Saponin in Primary Cultured Pterygium Fibroblasts in Comparison With Mitomycin C. ( Jang, SW; Jeong, H; Kim, JY; Lee, CM; Lee, H; Lee, JH; Park, SY; Shin, JA; Tchah, H, 2019) |
| " We aim to study the effects of Nutlin in pterygium and compare the effects of Nutlin and mitomycin C (MMC) in pterygium cell lines." | 7.88 | Cellular Proliferation and Migration of Human Pterygium Cells: Mitomycin Versus Small-Molecule Inhibitors. ( Cao, D; Chu, WK; Jhanji, V; Ng, TK; Pang, CP; Yip, YWY; Young, AL, 2018) |
| "To evaluate the long-term change in average corneal densities at 18 months after primary pterygium excision with topical adjuvant mitomycin-C application, particularly the relationship between anterior and posterior corneal layer densities." | 7.83 | Long-Term Density Changes in Corneal Layers After Primary Pterygium Excision With Topical Mitomycin-C. ( Belin, MW; Kam, KW; Kwok, RP; Young, AL, 2016) |
| "To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision." | 7.83 | Intraoperative application of 5-fluorouracil and mitomycin C aschemoadjuvants in primary pterygium surgery. ( Altay, Y; Balta, Ö, 2016) |
| "To describe complications after use of mitomycin C (MMC) as a surgical adjuvant in pterygium surgery." | 7.81 | Mitomycin C-associated scleral stromalysis after pterygium surgery. ( Lee, WB; Lindquist, TP, 2015) |
| " We aim to assess the changes in corneal scar density with serial Scheimpflug images following primary pterygium excision with topical application of mitomycin-C." | 7.81 | Monitoring corneal densities following primary pterygium excision with adjuvant topical mitomycin-C application--an observational study of corneal scar changes. ( Belin, MW; Kam, KW; Young, AL, 2015) |
| "To compare the long-term outcomes of primary pterygium surgery with combined conjunctival rotational autograft and mitomycin C (CRA-MMC), mitomycin C alone (MMC) and limbal conjunctival autograft (LCAU)." | 7.81 | Combined conjunctival rotational autograft with 0.02% mitomycin C in primary pterygium surgery: a long-term follow-up study. ( Cheng, LL; Ho, M; Jhanji, V; Tsim, NC; Young, AL, 2015) |
| "To retrospectively assess the efficacy of pterygium excision using bulbar conjunctival autograft with intraoperative mitomycin C (MMC) for primary pterygium." | 7.79 | [Pterygium excision using bulbar conjunctival autograft with intraoperative mitomycin C for primary pterygium: a retrospective assessment of 1832 eyes]. ( Masuda, A; Minami, K; Miyata, K; Nejima, R; Takahashi, K, 2013) |
| "Mitomycin C (MMC), as it could reduce tissue adhesions and scar formation, has been widely adopted in pterygium surgery to lower the recurrence rate." | 7.79 | [Mitomycin C related complications shouldn't be neglected in the pterygium surgery]. ( Shi, WY; Wang, FH, 2013) |
| "To assess the efficacy of subconjunctival bevacizumab injection as adjuvant therapy in the prevention of recurrence following the surgical treatment of pterygium by comparison with intraoperative mitomycin-C application." | 7.79 | Subconjunctival bevacizumab injection in the surgery of primary pterygium: comparison with intraoperative mitomycin-C. ( Doyduk-Kocabora, A; Fazil, K; Gulkilik, G; Kocabora, SM; Ozsutcu, M, 2013) |
| "To evaluate the safety and efficacy of using fibrin glue in cases of recurrent pterygium treated with pterygium excision and conjunctival autograft combined with mitomycin C." | 7.77 | Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue. ( Boimer, C; Lee, K; Shehadeh-Mashor, R; Slomovic, AR; Srinivasan, S; Tomkins, O, 2011) |
| "Mitomycin C (MMC) has been shown to have a therapeutic effect against human pterygium fibroblasts (HPFs) by inducing apoptosis." | 7.76 | Atomic force microscope-related study membrane-associated cytotoxicity in human pterygium fibroblasts induced by mitomycin C. ( Cai, J; Cai, X; Chen, Q; Wu, S; Yang, X, 2010) |
| "To evaluate the effectiveness of intra-operative Mitomycin-C application after pterygium surgery in Irrua, Nigeria." | 7.76 | Effectiveness of intra-operative Mitomycin-C in reducing the recurrence of pterygium in Irrua, Nigeria. ( Dawodu, OA; Eguaoje, IE; Enock, ME; Fuh, UC; Omoti, AE, 2010) |
| "To study the effects of mitomycin-C (MMC) on the corneal endothelium after pterygium surgery." | 7.76 | [Endothelial cells analysis after intraoperative mitomycin-C adjuvant pterygium simple excision surgery: a pilot study]. ( Benítez-Herreros, J; Gómez-San-Gil, Y; Montes-Mollón, MA; Pérez-Rico, C; Teus-Guezala, MA, 2010) |
| "To investigate whether mycophenolic acid (MPA) exerts antifibrotic effects on pterygium fibroblasts (PFB) with and without stimulation with fibrogenic cytokines, and to compare the efficacy of MPA with mitomycin (MMC) and dexamethasone (DXM) on PFB and tenon fibroblasts (TFB)." | 7.76 | Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro. ( Amer, R; Levi-Schaffer, F; Maftsir, G; Puxeddu, I; Rabinowich, L; Solomon, A, 2010) |
| "To perform a qualitative assessment of the topical side-effects of mitomycin C on cornea after pterygium surgery." | 7.75 | Corneal and conjunctival findings after mitomycin C application in pterygium surgery: an in-vivo confocal microscopy study. ( Beck, R; Guthoff, RF; Zhivov, A, 2009) |
| "To evaluate the changes in endothelial cell counts in patients after pterygium surgery with mitomycin C (MMC) 0." | 7.75 | The effect of mitomycin C on corneal endothelium in pterygium surgery. ( Bahar, I; Kaiserman, I; Lange, AP; Levinger, E; Sansanayudh, W; Slomovic, A; Slomovic, AR, 2009) |
| "02% mitomycin C (MMC) in the treatment of primary pterygium and to evaluate its safety and efficacy." | 7.75 | Prospective study on the safety and efficacy of combined conjunctival rotational autograft with intraoperative 0.02% mitomycin C in primary pterygium excision. ( Cheng, LL; Lam, DS; Lam, PT; Leung, GY; Tam, PM; Young, AL, 2009) |
| "To determine if the timing of mitomycin C (MMC) application during pterygium surgery affects endothelial cell loss." | 7.75 | Endothelial cell loss during pterygium surgery: importance of timing of mitomycin C application. ( Apel, I; Avisar, I; Avisar, R; Weinberger, D, 2009) |
| "To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery." | 7.75 | Intraoperative mitomycin C and corneal endothelium after pterygium surgery. ( Benítez-Herreros, J; Castro-Rebollo, M; Germain, F; Gómez-SanGil, Y; Montes-Mollón, MA; Paz-Moreno, J; Pérez-Rico, C; Teus, MA, 2009) |
| "To evaluate changes in endothelial cell count after pterygium surgery with 5-minute application of mitomycin C (MMC) 0." | 7.74 | Effect of mitomycin C in pterygium surgery on corneal endothelium. ( Avisar, I; Avisar, R; Bahar, I; Weinberger, D, 2008) |
| "Our purpose was to compare postoperative results of pterygium surgery between mini-flap technique and conjunctival autograft transplantation without application of mitomycin C." | 7.74 | Comparison of mini-flap technique and conjunctival autograft transplantation without mitomycin C in primary and recurrent pterygium. ( Chung, SH; Kim, M; Lee, HK; Lee, JH; Seo, KY, 2008) |
| "The primary objective of this study was to determine if intraoperative application of mitomycin C (MMC) is safe as an adjunct for pterygium surgery." | 7.74 | Efficacy and safety of intraoperative mitomycin C as adjunct therapy for pterygium surgery. ( Díaz, L; Emanuelli, A; Izquierdo, NJ; Villegas, VM, 2008) |
| "To observe the efficiency of intraoperative low-dose Mitomycin-C combined with conjunctival autograft in the treatment of recurrent pterygium." | 7.74 | Mitomycin C and conjunctival autograft for recurrent pterygium. ( Altiparmak, UE; Duman, S; Katircioğlu, YA; Yağci, R; Yalniz, Z, 2007) |
| "To compare three techniques combined with excision in the treatment of primary and recurrent pterygium: amniotic membrane transplantation, conjunctival autograft, and conjunctival autograft plus mitomycin C." | 7.74 | Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C. ( Altiparmak, UE; Duman, S; Katircioğlu, YA, 2007) |
| "We evaluated and compared the safety and efficacy of the conjunctival-limbal autograft, amniotic membrane transplantation, and intraoperative application of mitomycin C in 94 patients undergoing primary pterygium surgery and concluded that conjunctival-limbal autografting and amniotic membrane methods were more effective and safer than intraoperative mitomycin C." | 7.74 | Conjunctival-limbal autograft, amniotic membrane transplantation, and intraoperative mitomycin C for primary pterygium. ( Bilek, B; Cakmak, SS; Celik, Y; Keklikci, U; Unlu, MK, 2007) |
| "Subconjunctival injection of mitomycin C (MMC) before pterygium excision is a new adjunctive therapy to decrease pterygium recurrence." | 7.74 | Subconjunctival mitomycin C before pterygium excision: an ultrastructural study. ( Chang, YS; Chen, WC; Sze, CI; Tseng, SH; Wu, CL, 2008) |
| "To evaluate the long-term results and complications after bare sclera pterygium excision with local application of mitomycin C and consecutive smoothing of the wound area with an excimer laser (PTK)." | 7.73 | Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C. ( Daniel, J; Mennel, S; Meyer, CH; Rodrigues, EB; Walkow, T, 2005) |
| "Despite the established efficacy of mitomycin C (MMC) in preventing recurrence after pterygium surgery, there is no consensus on the optimal operative technique or dose of MMC." | 7.73 | Safety and efficacy of the technique of complete tenon's membrane excision and mitomycin C in pterygium surgery. ( Jacobson, L; Levy, RL; Naidu, S, 2005) |
| "To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium." | 7.73 | Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium. ( Amano, S; Hara, R; Miyai, T; Miyata, K; Nejima, R; Yonemura, T, 2005) |
| "To introduce a new technique of conjunctival reconstruction after primary pterygium excision, and to evaluate the efficacy of combined "symmetrical conjunctival flap transposition" and intraoperative low-dose mitomycin C application in preventing recurrence of primary pterygium." | 7.73 | Combined "symmetrical conjunctival flap transposition" and intraoperative low-dose mitomycin C in the treatment of primary pterygium. ( Kanpolat, A; Uçakhan, OO, 2006) |
| "To report a case of scleral melting noted 16 years after pterygium excision with postoperative adjuvant topical Mitomycin C (MMC)." | 7.73 | Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy. ( Azwa, JA; Ibrahim, M; Raihan, IS; Wan Norliza, WM, 2006) |
| "The aim of this study was to evaluate the effectiveness and safety of combining application of mitomycin and/or amnion transplantation when carrying out pterygium resection." | 7.73 | [Clinical study in combining application of mitomycin and amnion transplantation together with pterygium resection]. ( Huang, Y; Wang, B; Ye, Q, 2005) |
| "To evaluate the safety and efficacy of subconjunctival mitomycin C as adjunctive therapy before pterygium surgery." | 7.72 | Subconjunctival mitomycin C as adjunctive therapy before pterygium excision. ( Biser, S; Donnenfeld, ED; Doshi, S; Fromer, S; Perry, HD; Solomon, R, 2003) |
| "AMT with application of mitomycin C is effective in preventing pterygium recurrence and for improved ocular movement." | 7.72 | [Outcome of surgery for recurrent pterygium using intraoperative application of mitomycin C and amniotic membrane transplantation]. ( Kawasaki, S; Ohashi, Y; Shimamura, I; Uno, T, 2003) |
| "To evaluate the long-term postoperative outcome and complication rate of combined intraoperative low-dose mitomycin C application and free conjunctival autograft for the treatment of pterygium." | 7.72 | Combined mitomycin C application and free flap conjunctival autograft in pterygium surgery. ( Assia, EI; Gefen-Carmi, N; Jaeger-Roshu, S; Segev, F, 2003) |
| "To evaluate the long-term effects of intraoperative application of mitomycin C on the scleral thickness and the conjunctival epithelium at the surgical site of pterygium excision." | 7.72 | Long-term effects of mitomycin C in pterygium surgery on scleral thickness and the conjunctival epithelium. ( Frucht-Pery, J; Kaiserman, I; Landau, D; Raiskup, FD; Solomon, A, 2004) |
| "To evaluate the effect of combining amniotic membrane transplantation with mitomycin C to prevent the recurrence in primary pterygium surgery." | 7.72 | [Application of amnion membrane transplantation combine with mitomycin C in the treatment of pterygium]. ( Chen, J; Huang, Y; Huang, Z; Li, H; Lin, J, 2004) |
| "To evaluate long term complications after pterygium excision with mitomycin C (MMC) application." | 7.72 | Mitomycin C for pterygium: long term evaluation. ( Frucht-Pery, J; Ilsar, M; Landau, D; Raiskup, F; Solomon, A, 2004) |
| "To compare the rate of recurrence and complication after surgery for primary pterygium performed by one surgeon using either intraoperative mitomycin C or beta irradiation." | 7.70 | Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery. ( Amano, S; Eguchi, K; Eguchi, S; Motoyama, Y; Oshika, T, 2000) |
| "To study the efficacy and safety of amniotic membrane graft as an adjunctive therapy after removal of primary pterygium, and to compare the clinical outcome with conjunctival autograft and topical mitomycin C." | 7.70 | Amniotic membrane graft for primary pterygium: comparison with conjunctival autograft and topical mitomycin C treatment. ( Liau, SB; Ma, DH; See, LC; Tsai, RJ, 2000) |
| "The effectiveness of intra-operative mitomycin C on the recurrence rate of pterygium in patients undergoing primary pterygium excision was assessed." | 7.70 | Results of intra-operative 0.5mg/ml mitomycin C with 20mg depo steroid in the treatment of primary pterygium. ( Mpyet, C; Mypet, C; Oko, H, 2000) |
| "The effectiveness of instillation of mitomycin C eyedrops on the recurrence rate of pterygium was assessed in patients undergoing primary pterygium surgery." | 7.69 | Results of treatment with topical mitomycin C 0.02% following excision of primary pterygium. ( Leiba, H; Levartovsky, S; Rachmiel, R, 1995) |
| "The purposes of this study are to examine the complications and results of a novel approach to the use of mitomycin-C in pterygium surgery; to identify the lowest effective dosage required to prevent recurrence; and to select those high-risk pterygia that could benefit from mitomycin-C use." | 7.69 | Indications for and complications of mitomycin-C in pterygium surgery. ( Anduze, AL; Burnett, JM, 1996) |
| "Animal studies suggest that the decrease of intraocular pressure after application of mitomycin C is particularly mediated by toxic effects on the substance of ciliary body." | 7.69 | [Effect of local administration of mitomycin C on intraocular pressure]. ( Anders, N; Walkow, T; Wollensak, J, 1996) |
| " Thirty-three months before, the patient had a pterygium excised and mitomycin C, 0." | 7.68 | Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy. ( Fujitani, A; Hayasaka, S; Noda, S; Shibuya, Y, 1993) |
| "The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing." | 7.68 | Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992) |
| "In order to prevent recurrence of pterygium after excision we treated 21 patients postoperatively with Mitomycin-C-eye drops 0." | 7.68 | [Local mitomycin C therapy after excision of pterygium]. ( Goder, GJ; Möller, DE, 1992) |
| "Right corneal melting and scleral necrosis developed in a 77-year-old man 5 months after pterygium excision followed by topical administration of mitomycin C drops (0." | 7.68 | Corneal melting after pterygium removal followed by topical mitomycin C therapy. ( Climenhaga, DB; Ewing-Chow, DA; Gilmour, GR; Romanchuk, KG; Underhill, JH, 1992) |
| "The main outcome measures included the recurrence rate, residual conjunctival bed status, and complications from any of the surgical methods." | 6.90 | Fifteen-year results of a randomized controlled trial comparing 0.02% mitomycin C, limbal conjunctival autograft, and combined mitomycin C with limbal conjunctival autograft in recurrent pterygium surgery. ( Kam, KW; Young, AL, 2019) |
| "Each group consisted of 30 eyes." | 6.79 | Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence. ( Akkan, JC; Aras, C; Ayintap, E; Koytak, A; Ozsutcu, M, 2014) |
| "We found more pterygium recurrences in the MMC group." | 6.78 | [Conjunctival limbal autograft versus simple excision with intra-operative mitomycin C in pterygium surgery: a comparative study]. ( Bouguila, H; Boujemaa, C; Chebbi, A; Lajili, Z; Malek, I; Nacef, L; Saida Ayed, S; Zghal, I, 2013) |
| "Group B patients were treated with pterygium excision followed by mitomycin C 0." | 6.73 | Treatment of pterygium with conjunctival limbal autograft and mitomycin C--a comparative study. ( Biswas, MC; Chakroborty, M; Islam, MN; Mandal, R; Shaw, C, 2007) |
| "Patients were followed for recurrence (defined as fibrovascular tissue invading the cornea >1." | 6.71 | A randomised trial comparing 0.02% mitomycin C and limbal conjunctival autograft after excision of primary pterygium. ( Cheng, LL; Lam, DS; Leung, GY; Wong, AK; Young, AL, 2004) |
| " The authors designed a prospective, randomized study to explore the recurrence rate of pterygium after a single dosage of mitomycin C at the completion of pterygium excision, comparing it to postoperative mitomycin C therapy." | 6.69 | Intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. ( Basar, E; Gurler, B; Oguz, H, 1999) |
| " Combining the use of MMC with conjunctival autograft allows for decreased dosage and time of intraoperative exposure of mitomycin, thereby making it safer for application." | 6.69 | Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-Canadians. ( Law, FC; Wong, VA, 1999) |
| "To determine the rate of recurrence and complications after bare sclera excision of primary pterygia followed by low-dose mitomycin C (0." | 6.68 | A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium. ( Ariyasu, RG; Chen, PP; Kaza, V; LaBree, LD; McDonnell, PJ, 1995) |
| "Topical MMC led to 6 cases of recurrence (6." | 6.68 | Intraoperative mitomycin-C versus postoperative topical mitomycin-C drops for the treatment of pterygium. ( Amayem, A; Dabees, M; el-Maghraby, A; Elsherif, Z; Helal, M; Messiha, N, 1996) |
| "Nine patients showed recurrence occurring within first 6 months of surgery." | 6.67 | Role of mitomycin C in pterygium surgery. ( Mahar, PS; Nwokora, GE, 1993) |
| " Here we propose and describe modified bare sclera technique combined with the intraoperative application of MMC for pterygium excision." | 5.62 | Pterygium excision with modified bare sclera technique combined with mitomycin C. ( Aziza, Y; Inatomi, T; Kinoshita, S; Sotozono, C, 2021) |
| "Pterygium is a degenerative disease that characterized by excessive fibrovascular proliferation." | 5.56 | Targeted delivery of mitomycin C-loaded and LDL-conjugated mesoporous silica nanoparticles for inhibiting the proliferation of pterygium subconjunctival fibroblasts. ( Shao, T; Wang, S; Wang, Y; Wu, M; Zhang, F, 2020) |
| "SCG reduces the appearance of recurrences in primary pterygium surgery." | 5.35 | Efficacy of mitomycin C associated with direct conjunctival closure and sliding conjunctival graft for pterygium surgery. ( Alió, JL; de la Hoz, F; Javaloy, J; Montero, JA; Ruiz-Moreno, JM; Sala, E, 2008) |
| "To evaluate the influence of preoperative mitomycin C (MMC) on the proliferative behavior of fibroblasts and fibrovascular tissue derived from the primary pterygium using the immunohistochemical method (Ki67 and CD34)." | 5.30 | Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial. ( Alves, MR; Chammas, R; de Azevedo Costa, ALF; Dos Santos Martins, TG; Furuzawa, KM, 2019) |
| "To investigate the effect of pterygium morphology on recurrence with preoperative subconjunctival injection of mitomycin-C in primary pterygium surgery." | 5.30 | Effect of Pterygium Morphology on Recurrence with Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery. ( Khan, FA; Niazi, SPK, 2019) |
| "Astigmatism was reduced." | 5.30 | Single application mitomycin C in primary pterygium surgery. ( Pommerencke, C, 1998) |
| "Patients were followed up for signs of recurrence and complications." | 5.29 | [Pterygium excision with intra-operative administration of low dosage mitomycin C]. ( Akova, Y; Heiligenhaus, A; Lung, E; Schrenk, M; Waubke, TN, 1995) |
| " Although topical mitomycin-C is effective as an adjunct to pterygium surgery and may reduce recurrence, the safety and efficacy of various concentrations and dosing schedules need further definition." | 5.29 | Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. ( Dougherty, PJ; Hardten, DR; Lindstrom, RL, 1996) |
| "No recurrence was noted within the 1st year in the primary pterygium group, whereas recurrence was observed in 3/24 eyes that had been treated for recurrent pterygium, equivalent to a recurrence rate of 12." | 5.28 | Pterygium excision using 193-nm excimer laser smoothing and topical mitomycin C. ( Schnelle, B; Seiler, T; Wollensak, J, 1992) |
| "The rates of recurrence (5% to 9%) and complications in eyes that had undergone excision and mitomycin C instillation were less than those in eyes that had had excision only." | 5.28 | Postoperative instillation of mitomycin C in the treatment of recurrent pterygium. ( Hayasaka, S; Noda, S; Setogawa, T; Yamamoto, Y, 1989) |
| "To evaluate and compare the recurrence rate and complications of conjunctival autograft (CAG) combined with preoperative mitomycin C (MMC) injection versus CAG with intraoperative local MMC over the medial rectus muscle tendon in primary pterygium." | 5.27 | Conjunctival Autograft Combined With Either Preoperative Mitomycin C Injection or Intraoperative Local Mitomycin C Over the Medial Rectus Muscle Tendon in Primary Pterygium Surgery. ( Abdelrahman, A; Abdulhalim, BH; Gad, AAM; Lotfy, A; Samir, A, 2018) |
| "02 % mitomycin C (MMC) to treat recurrent pterygium." | 5.24 | Limbal conjunctival versus amniotic membrane in the intraoperative application of mitomycin C for recurrent pterygium: a randomized controlled trial. ( Chen, R; Huang, G; Liu, S; Ma, W; Yin, X; Zhou, S, 2017) |
| "To compare the effectiveness of preoperative subconjunctival injection of Mitomycin-C at 24-hour and at one month before primary pterygium excision." | 5.24 | Effectiveness of Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery. ( Akhter, N; Awais, M; Ishaq, M; Khan, FA; Niazi, ShP, 2017) |
| "To compare the results of amniotic membrane transplantation (AMT) combined with mitomycin C (MMC) to the results of free conjunctival autograft (CA) combined with MMC for the treatment of patients with recurrent pterygium." | 5.20 | Comparison of Two Techniques for the Treatment of Recurrent Pterygium: Amniotic Membrane vs Conjunctival Autograft Combined with Mitomycin C. ( Altiparmak, U; Cakir, B; Engur Goktas, S; Katırcıoglu, YA; Ornek, F; Singar, E, 2015) |
| "To compare the recurrence rates and complications associated with instillation of topical mitomycin C, cyclosporine, and bevacizumab after primary pterygium surgery." | 5.20 | A Comparative Study of Topical Mitomycin C, Cyclosporine, and Bevacizumab after Primary Pterygium Surgery. ( Choi, S; Hwang, S, 2015) |
| "To identify the determinants of recurrence following primary pterygium excision combined with conjunctival autograft (CAG) and intraoperative use of Mitomycin C (MMC) or 5-Fluorouracil (5-FU)." | 5.19 | Risk factors for pterygium recurrence after surgical excision with combined conjunctival autograft (CAG) and intraoperative antimetabolite use. ( Ashaye, AO; Baiyeroju, AM; Bekibele, CO; Fasina, O; Ibrahim, AO; Ogun, OA; Ogundipe, AO; Olusanya, BA, 2014) |
| "To compare the long-term outcome of pterygium surgery and the long-term effect on endothelial counts after mitomycin C (MMC) or limbal conjunctival autograft (LCAU) in pterygium surgery." | 5.17 | Ten-year results of a randomized controlled trial comparing 0.02% mitomycin C and limbal conjunctival autograft in pterygium surgery. ( Cheng, LL; Ho, M; Jhanji, V; Young, AL, 2013) |
| "This prospective study included 54 eyes with primary nasal pterygia that underwent pterygium surgery with a bare-sclera technique and intraoperative mitomycin C application." | 5.17 | Effects of intraoperative steroid injection on the outcome of pterygium surgery. ( Behrouz, MJ; Ghassemi, H; Kheirkhah, A; Nazari, R; Raju, VK; Safi, H, 2013) |
| "To compare the 4-year outcome of primary pterygium excision using intraoperative mitomycin C (MMC) with suturing a free conjunctival autograft (CA)." | 5.16 | Intraoperative mitomycin C versus autologous conjunctival autograft in surgery of primary pterygium with four-year follow-up. ( Artzén, D; Kopp, ED; Koranyi, G; Seregard, S, 2012) |
| "To compare the outcomes of free conjunctival autograft (CAU) versus conjunctival-limbal autograft (CLAU) in the prevention of recurrence after pterygium surgery with adjunctive mitomycin C application in patients with primary or recurrent pterygia." | 5.16 | Randomized trial of pterygium surgery with mitomycin C application using conjunctival autograft versus conjunctival-limbal autograft. ( Adelpour, M; Behrouz, MJ; Hashemi, H; Kheirkhah, A; Nikdel, M; Rajabi, MB, 2012) |
| "To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium." | 5.16 | Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery. ( Khalifa, YM; Zaky, KS, 2012) |
| "To evaluate changes in corneal endothelial cell counts after pterygium surgery with application of mitomycin C (MMC) either on the perilimbal sclera or in the subconjunctival space." | 5.15 | Effects of mitomycin C on corneal endothelial cell counts in pterygium surgery: role of application location. ( Behrouz, MJ; Hashemian, H; Izadi, A; Kheirkhah, A; Kiarudi, MY; Nazari, R, 2011) |
| "To evaluate postoperative outcome and recurrence rate after primary pterygium excision using preoperative Mitomycin C (MMC) injection versus limbal conjunctival autograft transplantation (LCAT)." | 5.15 | Preoperative subpterygial mitomycin C injection versus limbal conjunctival autograft transplantation for prevention of pterygium recurrence. ( Farahat, HG; Mandour, SS; Mohamed, HM, 2011) |
| "To evaluate and compare the recurrence rates and complications between 2 therapeutic methods for primary pterygium: subconjunctival injection of mitomycin C (MMC) 1 month before bare scleral excision and conjunctival rotational flap with intraoperative MMC use." | 5.14 | Preoperative subpterygeal injection vs intraoperative mitomycin C for pterygium removal: comparison of results and complications. ( Daneshvar, R; Ghate, MF; Ghooshkhanehi, H; Khakshoor, H; Razavi, ME; Shakeri, MT, 2010) |
| "To compare the efficacy and complications of conjunctival limbal autograft (CLAU) and amniotic membrane transplantation (AMT) vsintraoperative mitomycin C (MMC) and AMT for treatment of recurrent pterygium." | 5.13 | Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium. ( Amozadeh, J; Fakhraee, G; Fallah, MR; Golabdar, MR; Moghimi, S; Zare, MA, 2008) |
| "To compare the clinical outcome of pterygium surgery combining intraoperative mitomycin C (MMC) with a free conjunctival autograft, with three other methods of pterygium surgery, including intraoperative MMC alone, conjunctival autograft alone, and bare sclera without adjunctive treatment." | 5.12 | Conjunctival autografting combined with low-dose mitomycin C for prevention of primary pterygium recurrence. ( Frucht-Pery, J; Ilsar, M; Landau, D; Orucov, F; Raiskup, F; Solomon, A, 2006) |
| " Computerized videokeratography was performed in 54 patients (55 eyes) with primary pterygium before and after pterygium excision using bare sclera technique combined with intraoperative mitomycin C." | 5.11 | Effect of pterygium surgery on corneal topography: a prospective study. ( Avisar, R; Bahar, I; Loya, N; Weinberger, D, 2004) |
| "To evaluate the safety and efficacy of a preoperative injection of mitomycin C (MMC) in combined pterygium and cataract surgery." | 5.11 | Preoperative injection of mitomycin C in combined pterygium and cataract surgery. ( Avisar, R; Bar, S; Weinberger, D, 2005) |
| "To determine if a pterygium surgical procedure consisting of minimal conjunctival removal, excision of the hypertrophic subconjunctival fibrovascular tissue, application of mitomycin 0." | 5.11 | Pterygium surgery with mitomycin and tarsorrhaphy. ( Hamilton, DL; Williams, BL; Williams, EE; Wood, TO, 2005) |
| "02% mitomycin C is safe and more effective than a 3-minute application in recurrence of pterygium." | 5.10 | Intraoperative mitomycin C 0.02% for pterygium: effect of duration of application on recurrence rate. ( Appel, I; Avisar, R; Gaton, DD; Loya, N; Weinberger, D, 2003) |
| "To evaluate the safety and efficacy of single-drop instillation of mitomycin C (MMC) in pterygium surgery and to compare the results with both postoperative and intraoperative application of MMC." | 5.10 | Comparison of single-drop mitomycin C regime with other mitomycin C regimes in pterygium surgery. ( Gupta, VP; Saxena, T, 2003) |
| "Limbal conjunctival autograft transplantation or low-dose intraoperative mitomycin C application with conjunctival flap technique was performed on recurrent pterygium cases." | 5.09 | A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap. ( Mutlu, FM; Sobaci, G; Tatar, T; Yildirim, E, 1999) |
| "A prospective, randomised, double blind, placebo controlled study of intraoperative mitomycin C as adjunctive treatment of primary pterygium was conducted." | 5.08 | Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium. ( Cano-Parra, J; Diaz-Llopis, M; Maldonado, MJ; Menezo, JL; Vila, E, 1995) |
| "02% mitomycin C is an effective treatment for prevention of recurrence of pterygium." | 5.08 | Intraoperative application of topical mitomycin C for pterygium surgery. ( Frucht-Pery, J; Ilsar, M; Siganos, CS, 1996) |
| "The study was designed to evaluate the long term results of intraoperative mitomycin C in patients with one recurrence of pterygium." | 5.08 | Long term results of intraoperative mitomycin C in the treatment of recurrent pterygium. ( Carpineto, P; Ciancaglini, M; Enrico Gallenga, P; Mastropasqua, L, 1996) |
| "In this clinical trial the recurrence-rate after primary pterygium-excision, phototherapeutic keratectomy with the ArF:excimerlaser and local application of mitomycin C should be estimated." | 5.08 | [Incidence of recurrence after primary pterygium excision, phototherapeutic keratectomy with the ArF:Excimer laser and local mitomycin C administration]. ( Anders, N; Antoni, HJ; Walkow, T; Wollensak, J, 1996) |
| "to investigate, in the first report in Central Africa, the influence of tropical Mitomycin C on the recurrence rate and on the complications after surgical treatment for primary pterygium." | 5.08 | Postoperative instillation of 0.04% mitomycin C in the treatment of primary pterygium in Zaire. ( Kaimbo Wa Kaimbo, D, 1996) |
| "To determine the minimum effective dosage, most effective route of administration and long-term effects of mitomycin C for prevention of recurrence after pterygium surgery." | 5.08 | Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. ( Alves, MR; Ambrosio, LE; Cardillo, JA; Jose, NK; Poterio, MB, 1995) |
| "Conjunctival autograft transplantation and postoperative mitomycin therapy are two adjuvant treatment methods shown to lessen the high pterygium recurrence rate seen with simple excision alone." | 5.08 | Intraoperative mitomycin in primary pterygium excision. A prospective, randomized trial. ( Diaz, MD; Kloess, PM; Manning, CA; Yee, RW, 1997) |
| "04% mitomycin-C, either postoperatively for 2 weeks or intraoperatively as a single dose, as an adjunct in the surgical treatment of primary pterygium was evaluated." | 5.08 | Intraoperative and postoperative use of mitomycin-C in the treatment of primary pterygium. ( Calişkan, S; Irkeç, M; Orhan, M, 1996) |
| "Mitomycin-C has been shown to dramatically reduce pterygium recurrence rates; however, its use has been associated with serious complications, especially in higher cumulative doses." | 5.08 | Topical mitomycin-C for pterygia: is single application appropriate? ( Rubinfeld, RS; Stein, RM, 1997) |
| "02 mg/ml, with an accurate size of sterile sponge applied to bare sclera after primary pterygium excision decreases the rate of recurrence to a greater extent than does gentamicin solution and is not associated with severe complications." | 5.08 | Randomized trial of intraoperative mitomycin C in surgery for pterygium. ( Das, GK; Kumar, A; Panda, A; Tuli, SW, 1998) |
| "A prospective study was carried out to assess the recurrence rate of pterygium with conjunctival autograft versus the use of topical mitomycin C." | 5.08 | Conjunctival autograft versus topical mitomycin C in treatment of pterygium. ( Mahar, PS, 1997) |
| "The purpose of the study was to examine the efficacy of intraoperative mitomycin C (MMC) in preventing recurrence of pterygium after excision and the postoperative complications encountered." | 5.08 | Intraoperative mitomycin C to prevent recurrence of pterygium after excision: a 30-month follow-up study. ( Chew, S; Fan, DS; Kwok, PS; Lam, DS; Tso, MO; Wong, AK, 1998) |
| "A surgical technique was designed to improve safety after pterygium excision with intraoperative application of mitomycin-C (MMC)." | 5.08 | An improved surgical technique for pterygium excision with intraoperative application of mitomycin-C. ( Alves, MR; Cardillo, JA; José, NK; Potério, MB, 1998) |
| " Topical Mitomycin caused: iritis, conjunctival irritation, excessive lacrymation, photophobia, ocular pain; Thio-tepa caused: photophobia, foreign body sensation, headache." | 5.08 | [A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results]. ( Kayembe, L; Ngoy, D, 1998) |
| "The effectiveness of intraoperative administration of mitomycin C and the occurrence of postoperative complications have been evaluated in 30 white patients with one recurrence of pterygium." | 5.07 | Effectiveness of intraoperative mitomycin C in the treatment of recurrent pterygium. ( Carpineto, P; Ciancaglini, M; Gallenga, PE; Lobefalo, L; Mastropasqua, L, 1994) |
| "We studied the recurrence rate of pterygium after administration of a single dosage of topical mitomycin C at the completion of pterygium surgery." | 5.07 | Single dosage of mitomycin C for prevention of recurrent pterygium: preliminary report. ( Frucht-Pery, J; Hemo, I; Ilsar, M, 1994) |
| "The administration of high doses of topical mitomycin C after pterygium excision causes a variety of complications." | 5.07 | The use of low-dose mitomycin C for prevention of recurrent pterygium. ( Frucht-Pery, J; Ilsar, M, 1994) |
| " Use of conjunctival or limbal autografts or mitomycin C during or after pterygium excision reduced recurrence compared with bare sclera excision alone in most studies of primary or recurrent pterygium." | 4.89 | Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology. ( Deng, SX; Jacobs, DS; Kaufman, SC; Lee, WB; Rosenblatt, MI; Shtein, RM, 2013) |
| "To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C." | 4.81 | Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. ( Lin, JM; Shy, JD; Tsai, YY, 2002) |
| "Bare sclera resection with and without use of mitomycin C and conjunctival autograft placement are three surgical techniques currently in use for the treatment of primary pterygium." | 4.80 | Meta-analysis on the recurrence rates after bare sclera resection with and without mitomycin C use and conjunctival autograft placement in surgery for primary pterygium. ( Rocha, G; Sánchez-Thorin, JC; Yelin, JB, 1998) |
| "Although conjunctival autograft (CAU) and amniotic membrane grafting (AMG) with mitomycin-C (MMC) are most effective for the treatment of primary pterygium, the optimal surgical treatment of recurrent pterygium is not well established." | 4.31 | Comparison of surgical techniques for recurrent pterygium. ( Kim, YJ; Lee, HJ; Rao, R, 2023) |
| " Mitomycin C has been used adjunctively in various procedures, including pterygium excision." | 4.31 | Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report. ( Chaidaroon, W; Pathanapitoon, K; Upaphong, P, 2023) |
| "To report on the outcomes of recurrent pterygium treated by ipsilateral simple limbal epithelial transplantation (SLET), mitomycin, tenonectomy, and amniotic membrane transplantation." | 4.02 | Outcomes of Ipsilateral Simple Limbal Epithelial Transplantation, Tenonectomy, Mitomycin and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium. ( Cohen, E; Einan-Lifshitz, A; Mednick, Z; Mimouni, M; Santaella, G; Slomovic, A; Sorkin, N; Trinh, T, 2021) |
| "This study described the clinical features of patients with pterygium and analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting combined with intraoperative mitomycin C, and amniotic membrane grafting." | 4.02 | Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up. ( Alhabdan, N; Alluhaidan, A; Almalki, A; Alqahtani, B; Alsarhani, A; Alsarhani, W; Alshahrani, S; Alsumari, O; Showail, M, 2021) |
| "To investigate the antifibrotic effects of sakuraso-saponin on a primary culture of human pterygium fibroblasts (HPFs) and normal human Tenon fibroblasts (HTFs) as compared to the effects of mitomycin C (MMC)." | 3.91 | Antifibrotic Effects of Sakuraso-Saponin in Primary Cultured Pterygium Fibroblasts in Comparison With Mitomycin C. ( Jang, SW; Jeong, H; Kim, JY; Lee, CM; Lee, H; Lee, JH; Park, SY; Shin, JA; Tchah, H, 2019) |
| " Thirty patients underwent primary pterygium excision with adjuvant topical mitomycin-C application were followed up and imaged with Pentacam system at postoperative weeks 1, 4, 12 and month 18." | 3.91 | Novel grid and sectoral analyses in monitoring corneal scars. ( Belin, MW; Kam, KW; Kwok, RPW; Li, A; Young, AL, 2019) |
| " We aim to study the effects of Nutlin in pterygium and compare the effects of Nutlin and mitomycin C (MMC) in pterygium cell lines." | 3.88 | Cellular Proliferation and Migration of Human Pterygium Cells: Mitomycin Versus Small-Molecule Inhibitors. ( Cao, D; Chu, WK; Jhanji, V; Ng, TK; Pang, CP; Yip, YWY; Young, AL, 2018) |
| "To describe complications after use of mitomycin C (MMC) as a surgical adjuvant in pterygium surgery." | 3.81 | Mitomycin C-associated scleral stromalysis after pterygium surgery. ( Lee, WB; Lindquist, TP, 2015) |
| " We aim to assess the changes in corneal scar density with serial Scheimpflug images following primary pterygium excision with topical application of mitomycin-C." | 3.81 | Monitoring corneal densities following primary pterygium excision with adjuvant topical mitomycin-C application--an observational study of corneal scar changes. ( Belin, MW; Kam, KW; Young, AL, 2015) |
| "To compare the long-term outcomes of primary pterygium surgery with combined conjunctival rotational autograft and mitomycin C (CRA-MMC), mitomycin C alone (MMC) and limbal conjunctival autograft (LCAU)." | 3.81 | Combined conjunctival rotational autograft with 0.02% mitomycin C in primary pterygium surgery: a long-term follow-up study. ( Cheng, LL; Ho, M; Jhanji, V; Tsim, NC; Young, AL, 2015) |
| "To analyze conjunctival cytological features 1 month after pterygium excision using limbo-conjunctival autograft (LCA) with and without intraoperative mitomycin C and to assess tissue short-term evolution in both situations." | 3.81 | Conjunctival Short-term Evolution after Pterygium Excision. ( Dolores Merindano, M; Julio, G; Lluch, S; Pujol, P; Soledad Marqués-Calvo, M, 2015) |
| "Intraoperative mitomycin C (MMC) is widely used to prevent pterygium recurrence and glaucoma filtering bleb failure, but it has been shown to induce corneal inflammation and cell death." | 3.80 | Dexamethasone modifies mitomycin C-triggered interleukin-8 secretion in isolated human Tenon's capsule fibroblasts. ( Chang, SW; Chen, TC; Chou, SF; Ho, WT, 2014) |
| "To compare corneal astigmatism after pterygium excision, using limbal-conjunctival autograft (LCA) with and without mitomycin C (MMC) and to establish a threshold for postoperative astigmatism reduction." | 3.80 | Threshold to predict astigmatism reduction after pterygium excision. ( de Carvalho, AM; Julio, G; Kostov, B; Martí-Huguet, T; Pujol, P, 2014) |
| "To retrospectively assess the efficacy of pterygium excision using bulbar conjunctival autograft with intraoperative mitomycin C (MMC) for primary pterygium." | 3.79 | [Pterygium excision using bulbar conjunctival autograft with intraoperative mitomycin C for primary pterygium: a retrospective assessment of 1832 eyes]. ( Masuda, A; Minami, K; Miyata, K; Nejima, R; Takahashi, K, 2013) |
| "Mitomycin C (MMC), as it could reduce tissue adhesions and scar formation, has been widely adopted in pterygium surgery to lower the recurrence rate." | 3.79 | [Mitomycin C related complications shouldn't be neglected in the pterygium surgery]. ( Shi, WY; Wang, FH, 2013) |
| "To establish the usefulness of grading system based on the size and extent of corneal involvement in predicting recurrence in patients undergoing primary pterygium excision with intraoperative use of adjunctive topical Mitomycin-C (MMC)." | 3.79 | Pterygium recurrence related to its size and corneal involvement. ( Mahar, PS; Manzar, N, 2013) |
| "To evaluate the safety and efficacy of using fibrin glue in cases of recurrent pterygium treated with pterygium excision and conjunctival autograft combined with mitomycin C." | 3.77 | Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue. ( Boimer, C; Lee, K; Shehadeh-Mashor, R; Slomovic, AR; Srinivasan, S; Tomkins, O, 2011) |
| "To evaluate the effectiveness of intra-operative Mitomycin-C application after pterygium surgery in Irrua, Nigeria." | 3.76 | Effectiveness of intra-operative Mitomycin-C in reducing the recurrence of pterygium in Irrua, Nigeria. ( Dawodu, OA; Eguaoje, IE; Enock, ME; Fuh, UC; Omoti, AE, 2010) |
| "To report a case of necrotizing scleritis after pterygium surgery with conjunctival autografting (CA) and intraoperative Mitomycin C (MMC) and its treatment with amniotic membrane transplantation (AMT) and systemic steroid." | 3.76 | Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation. ( Akova, YA; Borazan, M; Karalezli, A; Kucukerdonmez, C, 2010) |
| "To investigate whether mycophenolic acid (MPA) exerts antifibrotic effects on pterygium fibroblasts (PFB) with and without stimulation with fibrogenic cytokines, and to compare the efficacy of MPA with mitomycin (MMC) and dexamethasone (DXM) on PFB and tenon fibroblasts (TFB)." | 3.76 | Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro. ( Amer, R; Levi-Schaffer, F; Maftsir, G; Puxeddu, I; Rabinowich, L; Solomon, A, 2010) |
| "To perform a qualitative assessment of the topical side-effects of mitomycin C on cornea after pterygium surgery." | 3.75 | Corneal and conjunctival findings after mitomycin C application in pterygium surgery: an in-vivo confocal microscopy study. ( Beck, R; Guthoff, RF; Zhivov, A, 2009) |
| "02% mitomycin C (MMC) in the treatment of primary pterygium and to evaluate its safety and efficacy." | 3.75 | Prospective study on the safety and efficacy of combined conjunctival rotational autograft with intraoperative 0.02% mitomycin C in primary pterygium excision. ( Cheng, LL; Lam, DS; Lam, PT; Leung, GY; Tam, PM; Young, AL, 2009) |
| "Our purpose was to compare postoperative results of pterygium surgery between mini-flap technique and conjunctival autograft transplantation without application of mitomycin C." | 3.74 | Comparison of mini-flap technique and conjunctival autograft transplantation without mitomycin C in primary and recurrent pterygium. ( Chung, SH; Kim, M; Lee, HK; Lee, JH; Seo, KY, 2008) |
| "The primary objective of this study was to determine if intraoperative application of mitomycin C (MMC) is safe as an adjunct for pterygium surgery." | 3.74 | Efficacy and safety of intraoperative mitomycin C as adjunct therapy for pterygium surgery. ( Díaz, L; Emanuelli, A; Izquierdo, NJ; Villegas, VM, 2008) |
| "To observe the efficiency of intraoperative low-dose Mitomycin-C combined with conjunctival autograft in the treatment of recurrent pterygium." | 3.74 | Mitomycin C and conjunctival autograft for recurrent pterygium. ( Altiparmak, UE; Duman, S; Katircioğlu, YA; Yağci, R; Yalniz, Z, 2007) |
| "To compare three techniques combined with excision in the treatment of primary and recurrent pterygium: amniotic membrane transplantation, conjunctival autograft, and conjunctival autograft plus mitomycin C." | 3.74 | Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C. ( Altiparmak, UE; Duman, S; Katircioğlu, YA, 2007) |
| "We evaluated and compared the safety and efficacy of the conjunctival-limbal autograft, amniotic membrane transplantation, and intraoperative application of mitomycin C in 94 patients undergoing primary pterygium surgery and concluded that conjunctival-limbal autografting and amniotic membrane methods were more effective and safer than intraoperative mitomycin C." | 3.74 | Conjunctival-limbal autograft, amniotic membrane transplantation, and intraoperative mitomycin C for primary pterygium. ( Bilek, B; Cakmak, SS; Celik, Y; Keklikci, U; Unlu, MK, 2007) |
| "To determine the clinical significance of postoperative conjunctival inflammation noted at the third or fourth week after intraoperative application of mitomycin C and amniotic membrane transplantation for pterygium." | 3.74 | Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium. ( Casas, V; Kheirkhah, A; Raju, VK; Sheha, H; Tseng, SC, 2008) |
| "To evaluate the long-term results and complications after bare sclera pterygium excision with local application of mitomycin C and consecutive smoothing of the wound area with an excimer laser (PTK)." | 3.73 | Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C. ( Daniel, J; Mennel, S; Meyer, CH; Rodrigues, EB; Walkow, T, 2005) |
| "To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium." | 3.73 | Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium. ( Amano, S; Hara, R; Miyai, T; Miyata, K; Nejima, R; Yonemura, T, 2005) |
| "To introduce a new technique of conjunctival reconstruction after primary pterygium excision, and to evaluate the efficacy of combined "symmetrical conjunctival flap transposition" and intraoperative low-dose mitomycin C application in preventing recurrence of primary pterygium." | 3.73 | Combined "symmetrical conjunctival flap transposition" and intraoperative low-dose mitomycin C in the treatment of primary pterygium. ( Kanpolat, A; Uçakhan, OO, 2006) |
| "To report a case of scleral melting noted 16 years after pterygium excision with postoperative adjuvant topical Mitomycin C (MMC)." | 3.73 | Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy. ( Azwa, JA; Ibrahim, M; Raihan, IS; Wan Norliza, WM, 2006) |
| "The aim of this study was to evaluate the effectiveness and safety of combining application of mitomycin and/or amnion transplantation when carrying out pterygium resection." | 3.73 | [Clinical study in combining application of mitomycin and amnion transplantation together with pterygium resection]. ( Huang, Y; Wang, B; Ye, Q, 2005) |
| "The literature reveals that pterygium surgery focuses on adjunctive therapy such as mitomycin C and 5-fluorouracil, and beta irradiation with bare sclera technique to decrease recurrence." | 3.73 | Conjunctival flaps for pterygium surgery. ( Anduze, AL, 2006) |
| "To report the result of a combined surgical procedure of pterygium excision with simultaneous amniotic membrane transplant, conjunctival limbal autograft, and mitomycin C application in the management of two cases of chronically recurring pterygium." | 3.72 | Surgical treatment of chronically recurring pterygium. ( Bansal, AK; Murthy, SI; Rao, GN; Sangwan, VS, 2003) |
| "To evaluate the safety and efficacy of subconjunctival mitomycin C as adjunctive therapy before pterygium surgery." | 3.72 | Subconjunctival mitomycin C as adjunctive therapy before pterygium excision. ( Biser, S; Donnenfeld, ED; Doshi, S; Fromer, S; Perry, HD; Solomon, R, 2003) |
| "Sixteen (80%) of 20 cases developed severe scleral necrosis that required tectonic surgery after bare sclera pterygium excision with mitomycin C or beta-irradiation." | 3.72 | Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery. ( Tan, DT; Ti, SE, 2003) |
| "AMT with application of mitomycin C is effective in preventing pterygium recurrence and for improved ocular movement." | 3.72 | [Outcome of surgery for recurrent pterygium using intraoperative application of mitomycin C and amniotic membrane transplantation]. ( Kawasaki, S; Ohashi, Y; Shimamura, I; Uno, T, 2003) |
| "To evaluate long term complications after pterygium excision with mitomycin C (MMC) application." | 3.72 | Mitomycin C for pterygium: long term evaluation. ( Frucht-Pery, J; Ilsar, M; Landau, D; Raiskup, F; Solomon, A, 2004) |
| "The authors in a retrospective study assess the recurrence rate of pterygium after the application of a single intraoperative dosage of topical Mitomycin C during the pterygium excision." | 3.71 | [Peroperative use of mitomycin C in excision of primary pterygia]. ( Furdová, A; Hlavácková, K; Pesko, K, 2001) |
| "To compare the rate of recurrence and complication after surgery for primary pterygium performed by one surgeon using either intraoperative mitomycin C or beta irradiation." | 3.70 | Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery. ( Amano, S; Eguchi, K; Eguchi, S; Motoyama, Y; Oshika, T, 2000) |
| "The effectiveness of intra-operative mitomycin C on the recurrence rate of pterygium in patients undergoing primary pterygium excision was assessed." | 3.70 | Results of intra-operative 0.5mg/ml mitomycin C with 20mg depo steroid in the treatment of primary pterygium. ( Mpyet, C; Mypet, C; Oko, H, 2000) |
| "The effectiveness of instillation of mitomycin C eyedrops on the recurrence rate of pterygium was assessed in patients undergoing primary pterygium surgery." | 3.69 | Results of treatment with topical mitomycin C 0.02% following excision of primary pterygium. ( Leiba, H; Levartovsky, S; Rachmiel, R, 1995) |
| "The purposes of this study are to examine the complications and results of a novel approach to the use of mitomycin-C in pterygium surgery; to identify the lowest effective dosage required to prevent recurrence; and to select those high-risk pterygia that could benefit from mitomycin-C use." | 3.69 | Indications for and complications of mitomycin-C in pterygium surgery. ( Anduze, AL; Burnett, JM, 1996) |
| "Animal studies suggest that the decrease of intraocular pressure after application of mitomycin C is particularly mediated by toxic effects on the substance of ciliary body." | 3.69 | [Effect of local administration of mitomycin C on intraocular pressure]. ( Anders, N; Walkow, T; Wollensak, J, 1996) |
| " Thirty-three months before, the patient had a pterygium excised and mitomycin C, 0." | 3.68 | Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy. ( Fujitani, A; Hayasaka, S; Noda, S; Shibuya, Y, 1993) |
| "The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing." | 3.68 | Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992) |
| "In order to prevent recurrence of pterygium after excision we treated 21 patients postoperatively with Mitomycin-C-eye drops 0." | 3.68 | [Local mitomycin C therapy after excision of pterygium]. ( Goder, GJ; Möller, DE, 1992) |
| "Right corneal melting and scleral necrosis developed in a 77-year-old man 5 months after pterygium excision followed by topical administration of mitomycin C drops (0." | 3.68 | Corneal melting after pterygium removal followed by topical mitomycin C therapy. ( Climenhaga, DB; Ewing-Chow, DA; Gilmour, GR; Romanchuk, KG; Underhill, JH, 1992) |
| "The main outcome measures included the recurrence rate, residual conjunctival bed status, and complications from any of the surgical methods." | 2.90 | Fifteen-year results of a randomized controlled trial comparing 0.02% mitomycin C, limbal conjunctival autograft, and combined mitomycin C with limbal conjunctival autograft in recurrent pterygium surgery. ( Kam, KW; Young, AL, 2019) |
| "In the last few years, the treatment of pterygium has been developed and various new solutions have been used." | 2.82 | Update on overview of pterygium and its surgical management. ( Akbari, M, 2022) |
| "Each group consisted of 30 eyes." | 2.79 | Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence. ( Akkan, JC; Aras, C; Ayintap, E; Koytak, A; Ozsutcu, M, 2014) |
| "To compare the recurrence of pterygium between free conjunctival auto-graft and conjunctival rotation flap following simple surgical excision of pterygium." | 2.79 | Reducing postoperative pterygium recurrence: comparison of free conjunctival auto-graft and conjunctival rotation flap techniques. ( Akhter, W; Kausar, A; Masrur, A; Tayyab, A, 2014) |
| "At 6 months postoperatively, the recurrence rate of pterygium was 5." | 2.78 | Observation of long-term efficacy of corneal limbal conjunctival autografts in microscopy treatments of pterygium. ( Pi, M; Xu, F; Yang, Y, 2013) |
| "We found more pterygium recurrences in the MMC group." | 2.78 | [Conjunctival limbal autograft versus simple excision with intra-operative mitomycin C in pterygium surgery: a comparative study]. ( Bouguila, H; Boujemaa, C; Chebbi, A; Lajili, Z; Malek, I; Nacef, L; Saida Ayed, S; Zghal, I, 2013) |
| "Group B patients were treated with pterygium excision followed by mitomycin C 0." | 2.73 | Treatment of pterygium with conjunctival limbal autograft and mitomycin C--a comparative study. ( Biswas, MC; Chakroborty, M; Islam, MN; Mandal, R; Shaw, C, 2007) |
| "Patients were followed for recurrence (defined as fibrovascular tissue invading the cornea >1." | 2.71 | A randomised trial comparing 0.02% mitomycin C and limbal conjunctival autograft after excision of primary pterygium. ( Cheng, LL; Lam, DS; Leung, GY; Wong, AK; Young, AL, 2004) |
| " In an effort to determine a way to better reduce the recurrence of pterygia, we compared the efficacy and safety of amniotic membrane graft (AMG) alone and AMG combined with intraoperative mitomycin C after excision of recurrent pterygia." | 2.71 | Comparison of amniotic membrane graft alone or combined with intraoperative mitomycin C to prevent recurrence after excision of recurrent pterygia. ( Hwang, YS; Ma, DH; See, LC; Wang, SF, 2005) |
| " The authors designed a prospective, randomized study to explore the recurrence rate of pterygium after a single dosage of mitomycin C at the completion of pterygium excision, comparing it to postoperative mitomycin C therapy." | 2.69 | Intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. ( Basar, E; Gurler, B; Oguz, H, 1999) |
| " Combining the use of MMC with conjunctival autograft allows for decreased dosage and time of intraoperative exposure of mitomycin, thereby making it safer for application." | 2.69 | Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-Canadians. ( Law, FC; Wong, VA, 1999) |
| "To determine the rate of recurrence and complications after bare sclera excision of primary pterygia followed by low-dose mitomycin C (0." | 2.68 | A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium. ( Ariyasu, RG; Chen, PP; Kaza, V; LaBree, LD; McDonnell, PJ, 1995) |
| "Topical MMC led to 6 cases of recurrence (6." | 2.68 | Intraoperative mitomycin-C versus postoperative topical mitomycin-C drops for the treatment of pterygium. ( Amayem, A; Dabees, M; el-Maghraby, A; Elsherif, Z; Helal, M; Messiha, N, 1996) |
| "Nine patients showed recurrence occurring within first 6 months of surgery." | 2.67 | Role of mitomycin C in pterygium surgery. ( Mahar, PS; Nwokora, GE, 1993) |
| "Pterygium is a frequent ocular disease, where the major challenge is the high level of recurrence after its surgical removal." | 2.58 | Comparison among adjuvant treatments for primary pterygium: a network meta-analysis. ( Arruda, GV; Fonseca, EC; Rocha, EM, 2018) |
| " Here we propose and describe modified bare sclera technique combined with the intraoperative application of MMC for pterygium excision." | 1.62 | Pterygium excision with modified bare sclera technique combined with mitomycin C. ( Aziza, Y; Inatomi, T; Kinoshita, S; Sotozono, C, 2021) |
| "The pterygium is a frequent ultraviolet (UV) light-induced focal fibrovascular proliferation of the conjunctival tissue onto the cornea." | 1.62 | [Pterygium: pathogenesis, diagnosis and treatment]. ( Cursiefen, C; Heindl, LM; Rokohl, AC, 2021) |
| "Variable recurrence rates have been reported in the literature depending on the surgical technique." | 1.56 | [Outcome of pterygium excision after various surgical techniques-is excision with simple conjunctival closure still lege artis?] ( Barth, T; Eisenmann, K; Gamulescu, MA; Helbig, H; Zeman, F, 2020) |
| "To evaluate the recurrence rate after surgical excision, the pterygium patients were further subdivided into three groups according to the adjuvant therapy used to prevent recurrence." | 1.56 | Role of oxidative stress and vascular endothelial growth factor expression in pterygium pathogenesis and prevention of pterygium recurrence after surgical excision. ( Bayomy, NR; Elgouhary, SM; Elmazar, HF; Naguib, MI, 2020) |
| "Pterygium is a fibrovascular subepithelial growth of degenerative tissue over the limbus." | 1.48 | The Evolving Story of Pterygium. ( Cao, D; Chu, WK; Jhanji, V; Ng, TK; Pang, CP; Yip, YWY; Young, AL, 2018) |
| "Pterygium is a common ocular disease." | 1.42 | The results of pterygium excision at Thammasat Hospital. ( Bhornmata, A; Kampitak, K, 2015) |
| "Main outcome measures were recurrence, diplopia, and caruncle morphological characteristics." | 1.38 | New grading system to improve the surgical outcome of multirecurrent pterygia. ( Fu, Y; Liu, J; Tseng, SC; Xu, Y, 2012) |
| "Pterygium is a common UV-induced degeneration of the limbal conjunctiva." | 1.36 | [Pterygium. Etiology, clinical aspects and novel adjuvant therapies]. ( Cursiefen, C; Heindl, LM, 2010) |
| "To compare the pathologic changes, the recurrence rate and the ocular surface damage after 4 different types of pterygium surgical procedures." | 1.36 | [Clinical observation of therapeutic efficacy and study of conjunctival impression cytology after pterygium surgery]. ( Li, XM; Liu, JR; Wang, W, 2010) |
| "SCG reduces the appearance of recurrences in primary pterygium surgery." | 1.35 | Efficacy of mitomycin C associated with direct conjunctival closure and sliding conjunctival graft for pterygium surgery. ( Alió, JL; de la Hoz, F; Javaloy, J; Montero, JA; Ruiz-Moreno, JM; Sala, E, 2008) |
| "The overall recurrence rate was 178 (18." | 1.33 | Outcome of pterygium surgery: analysis over 14 years. ( Aasuri, MK; Bansal, AK; Fernandes, M; Gangopadhyay, N; Garg, P; Nutheti, R; Rao, GN; Sangwan, VS; Sridhar, MS, 2005) |
| "Pterygium is a common condition that has many and varied surgical management techniques." | 1.33 | Clinical outcome study of a modified surgical technique for pterygium excision. ( Ayliffe, W; Khemka, S; Massaoutis, P, 2006) |
| "There was only one recurrence in one of the three eyes in the group with recurrent pterygia (33." | 1.32 | Outcome of double-headed pterygium surgery. ( Avisar, R; Snir, M; Weinberger, D, 2003) |
| "Astigmatism was reduced." | 1.30 | Single application mitomycin C in primary pterygium surgery. ( Pommerencke, C, 1998) |
| "Patients were followed up for signs of recurrence and complications." | 1.29 | [Pterygium excision with intra-operative administration of low dosage mitomycin C]. ( Akova, Y; Heiligenhaus, A; Lung, E; Schrenk, M; Waubke, TN, 1995) |
| " Although topical mitomycin-C is effective as an adjunct to pterygium surgery and may reduce recurrence, the safety and efficacy of various concentrations and dosing schedules need further definition." | 1.29 | Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. ( Dougherty, PJ; Hardten, DR; Lindstrom, RL, 1996) |
| "No recurrence was noted within the 1st year in the primary pterygium group, whereas recurrence was observed in 3/24 eyes that had been treated for recurrent pterygium, equivalent to a recurrence rate of 12." | 1.28 | Pterygium excision using 193-nm excimer laser smoothing and topical mitomycin C. ( Schnelle, B; Seiler, T; Wollensak, J, 1992) |
| "The rates of recurrence (5% to 9%) and complications in eyes that had undergone excision and mitomycin C instillation were less than those in eyes that had had excision only." | 1.28 | Postoperative instillation of mitomycin C in the treatment of recurrent pterygium. ( Hayasaka, S; Noda, S; Setogawa, T; Yamamoto, Y, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.18) | 18.7374 |
| 1990's | 57 (24.89) | 18.2507 |
| 2000's | 77 (33.62) | 29.6817 |
| 2010's | 69 (30.13) | 24.3611 |
| 2020's | 21 (9.17) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, P | 1 |
| Raj, A | 1 |
| Gupta, A | 1 |
| Trinh, T | 2 |
| Mimouni, M | 2 |
| Mednick, Z | 2 |
| Einan-Lifshitz, A | 2 |
| Cohen, E | 2 |
| Santaella, G | 2 |
| Sorkin, N | 2 |
| Slomovic, A | 3 |
| Kim, YJ | 1 |
| Rao, R | 1 |
| Lee, HJ | 1 |
| Desai, NR | 2 |
| Adams, B | 2 |
| Palewski, M | 1 |
| Budnik, A | 1 |
| Konopińska, J | 1 |
| Akbari, M | 1 |
| Upaphong, P | 1 |
| Pathanapitoon, K | 1 |
| Chaidaroon, W | 1 |
| Eisenmann, K | 2 |
| Zeman, F | 2 |
| Helbig, H | 2 |
| Gamulescu, MA | 2 |
| Barth, T | 2 |
| Kam, KW | 4 |
| Young, AL | 11 |
| Dos Santos Martins, TG | 3 |
| Anschütz, A | 1 |
| Lee, H | 1 |
| Jeong, H | 1 |
| Lee, CM | 1 |
| Shin, JA | 1 |
| Jang, SW | 1 |
| Lee, JH | 2 |
| Park, SY | 1 |
| Kim, JY | 1 |
| Tchah, H | 1 |
| Yin, M | 1 |
| Li, H | 3 |
| Zhang, Y | 1 |
| Dai, H | 1 |
| Luo, F | 1 |
| Pan, Z | 1 |
| Chu, WK | 3 |
| Choi, HL | 1 |
| Bhat, AK | 1 |
| Jhanji, V | 5 |
| Elgouhary, SM | 1 |
| Elmazar, HF | 1 |
| Naguib, MI | 1 |
| Bayomy, NR | 1 |
| Wu, M | 1 |
| Wang, S | 1 |
| Wang, Y | 1 |
| Zhang, F | 1 |
| Shao, T | 1 |
| Trufanov, SV | 1 |
| Aziza, Y | 1 |
| Inatomi, T | 2 |
| Sotozono, C | 1 |
| Kinoshita, S | 2 |
| Rokohl, AC | 1 |
| Heindl, LM | 2 |
| Cursiefen, C | 2 |
| Alsarhani, W | 1 |
| Alshahrani, S | 1 |
| Showail, M | 1 |
| Alhabdan, N | 1 |
| Alsumari, O | 1 |
| Almalki, A | 1 |
| Alsarhani, A | 1 |
| Alluhaidan, A | 1 |
| Alqahtani, B | 1 |
| Jia, S | 1 |
| Chen, F | 1 |
| Wang, H | 1 |
| Kesavamoorthy, G | 1 |
| Lai, JS | 2 |
| Wong, IY | 1 |
| Chiu, K | 1 |
| Chan, JC | 1 |
| Josifovska, N | 1 |
| Szabó, DJ | 1 |
| Nagymihály, R | 1 |
| Veréb, Z | 1 |
| Facskó, A | 1 |
| Eriksen, K | 1 |
| Moe, MC | 1 |
| Petrovski, G | 1 |
| Fonseca, EC | 1 |
| Rocha, EM | 1 |
| Arruda, GV | 1 |
| Yulish, M | 1 |
| Khatib, A | 1 |
| Pikkel, J | 1 |
| Lotfy, A | 1 |
| Gad, AAM | 1 |
| Abdelrahman, A | 1 |
| Samir, A | 1 |
| Abdulhalim, BH | 1 |
| Cao, D | 2 |
| Ng, TK | 2 |
| Yip, YWY | 2 |
| Pang, CP | 2 |
| Li, A | 1 |
| Kwok, RPW | 1 |
| Belin, MW | 3 |
| de Azevedo Costa, ALF | 1 |
| Furuzawa, KM | 1 |
| Chammas, R | 1 |
| Alves, MR | 3 |
| Khan, FA | 2 |
| Niazi, SPK | 1 |
| Narsani, AK | 1 |
| Nagdev, PR | 1 |
| Memon, MN | 1 |
| Gupta, VP | 3 |
| Gupta, P | 2 |
| Ho, M | 2 |
| Cheng, LL | 4 |
| Kheirkhah, A | 5 |
| Nazari, R | 3 |
| Safi, H | 1 |
| Ghassemi, H | 2 |
| Behrouz, MJ | 4 |
| Raju, VK | 2 |
| Hirst, LW | 2 |
| Kaufman, SC | 3 |
| Jacobs, DS | 3 |
| Lee, WB | 4 |
| Deng, SX | 3 |
| Rosenblatt, MI | 3 |
| Shtein, RM | 3 |
| Fraunfelder, FW | 1 |
| Ozsutcu, M | 2 |
| Ayintap, E | 1 |
| Akkan, JC | 1 |
| Koytak, A | 1 |
| Aras, C | 1 |
| Masuda, A | 1 |
| Takahashi, K | 1 |
| Nejima, R | 2 |
| Minami, K | 1 |
| Miyata, K | 2 |
| Yang, Y | 1 |
| Pi, M | 1 |
| Xu, F | 1 |
| Shi, WY | 1 |
| Wang, FH | 1 |
| Katırcıoglu, YA | 3 |
| Altiparmak, U | 1 |
| Engur Goktas, S | 1 |
| Cakir, B | 1 |
| Singar, E | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intralesional Ranibizumab on Pterygium Vascularity, Size and Recurrence Rate: a Pilot Study[NCT02342392] | Phase 2/Phase 3 | 36 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| A Randomized Clinical Trial: Comparison of the Efficacy of Topical 0.2% Loteprednol Etabonate and Topical 0.1% Dexamethasone in Impending Recurrent Pterygium[NCT04075227] | Phase 4 | 108 participants (Actual) | Interventional | 2015-10-16 | Completed | ||
| The Comparison of Endothelial Cell Count in Pterygium Surgery Relating to the Timing of MMC Application.[NCT02641132] | Phase 4 | 62 participants (Anticipated) | Interventional | 2015-09-30 | Not yet recruiting | ||
| Tissue Engineering Conjunctiva Transplantation and Conjunctival Sac Formation for the Treatment of Pterygium and Atretoblepharia[NCT02911532] | 60 participants (Anticipated) | Interventional | 2016-10-01 | Recruiting | |||
| A Comparative Study Between Bare Scleral Technique and Conjunctival Autograft on Corneal Topography After Pterygium Surgery[NCT05812508] | 30 participants (Anticipated) | Observational [Patient Registry] | 2023-04-20 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for mitomycin and Pterygium
| Article | Year |
|---|---|
Evaluating the Efficacy and Safety of Different Pterygium Surgeries: A Review of the Literature.
Topics: Conjunctiva; Follow-Up Studies; Humans; Mitomycin; Pterygium; Recurrence; Treatment Outcome | 2022 |
Update on overview of pterygium and its surgical management.
Topics: Conjunctiva; Follow-Up Studies; Humans; Mitomycin; Pterygium; Recurrence; Transplantation, Autologou | 2022 |
Pterygium: new insights.
Topics: Animals; Conjunctiva; Follow-Up Studies; Mice; Mitomycin; Ophthalmologic Surgical Procedures; Pteryg | 2020 |
Comparison among adjuvant treatments for primary pterygium: a network meta-analysis.
Topics: Adjuvants, Immunologic; Alkylating Agents; Chemotherapy, Adjuvant; Conjunctiva; Cyclosporine; Fluoro | 2018 |
Pterygium: current concepts in pathogenesis and treatment.
Topics: Amnion; Conjunctiva; Humans; Mitomycin; Pterygium; Transplantation, Autologous | 2009 |
In vivo confocal microscopy, an inner vision of the cornea - a major review.
Topics: Administration, Topical; Animals; Contact Lenses; Cornea; Corneal Diseases; Diagnosis, Differential; | 2009 |
Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology.
Topics: Academies and Institutes; Alkylating Agents; Amnion; Conjunctiva; Humans; Mitomycin; Ophthalmologic | 2013 |
Efficacy of treatment for pterygium by autologous conjunctival transplantation and mitomycin C.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conjunctiva; Humans; Middle Aged; Mitomycin; Pterygium; | 2012 |
[Pterygium--menace, lying in wait].
Topics: Conjunctiva; Humans; Mitomycin; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Pterygium | 2003 |
Meta-analysis on the recurrence rates after bare sclera resection with and without mitomycin C use and conjunctival autograft placement in surgery for primary pterygium.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctiva; Female; Follow-Up Studies; | 1998 |
Ocular toxicity of mitomycin-C.
Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Eye; Eye Diseases; Filtering Surgery; Glaucoma; | 1999 |
Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.
Topics: Acute Disease; Humans; Intraoperative Period; Lactose; Lubrication; Male; Methylcellulose; Middle Ag | 2002 |
67 trials available for mitomycin and Pterygium
| Article | Year |
|---|---|
Fifteen-year results of a randomized controlled trial comparing 0.02% mitomycin C, limbal conjunctival autograft, and combined mitomycin C with limbal conjunctival autograft in recurrent pterygium surgery.
Topics: Autografts; Conjunctiva; Female; Follow-Up Studies; Forecasting; Humans; Intraoperative Period; Limb | 2019 |
Conjunctival Autograft Combined With Either Preoperative Mitomycin C Injection or Intraoperative Local Mitomycin C Over the Medial Rectus Muscle Tendon in Primary Pterygium Surgery.
Topics: Adult; Alkylating Agents; Conjunctiva; Female; Humans; Male; Middle Aged; Mitomycin; Oculomotor Musc | 2018 |
Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle Aged; M | 2019 |
Effect of Pterygium Morphology on Recurrence with Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery.
Topics: Adult; Age Factors; Alkylating Agents; Cohort Studies; Female; Humans; Injections; Male; Middle Aged | 2019 |
Ten-year results of a randomized controlled trial comparing 0.02% mitomycin C and limbal conjunctival autograft in pterygium surgery.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Cell Count; Combined Modality Therapy; Conjunctiva; Endo | 2013 |
Effects of intraoperative steroid injection on the outcome of pterygium surgery.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Conjunctivitis; Female; Follow-Up Studies; Glucocorticoids | 2013 |
Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Conjunctiva; Dose-Re | 2014 |
Observation of long-term efficacy of corneal limbal conjunctival autografts in microscopy treatments of pterygium.
Topics: Autografts; Conjunctiva; Follow-Up Studies; Humans; Microscopy; Mitomycin; Postoperative Complicatio | 2013 |
Comparison of Two Techniques for the Treatment of Recurrent Pterygium: Amniotic Membrane vs Conjunctival Autograft Combined with Mitomycin C.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Amnion; Combined Modality Therapy; Conjunctiva; F | 2015 |
Reducing postoperative pterygium recurrence: comparison of free conjunctival auto-graft and conjunctival rotation flap techniques.
Topics: Adult; Alkylating Agents; Conjunctiva; Female; Follow-Up Studies; Free Tissue Flaps; Humans; Male; M | 2014 |
Risk factors for pterygium recurrence after surgical excision with combined conjunctival autograft (CAG) and intraoperative antimetabolite use.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; | 2014 |
A Comparative Study of Topical Mitomycin C, Cyclosporine, and Bevacizumab after Primary Pterygium Surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Alkylating Agents; Angiogenesis Inhibitors; Bevaci | 2015 |
Limbal conjunctival versus amniotic membrane in the intraoperative application of mitomycin C for recurrent pterygium: a randomized controlled trial.
Topics: Administration, Topical; Biological Dressings; Conjunctiva; Eye Movements; Female; Follow-Up Studies | 2017 |
Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Conjunctiva; Conjunctivitis; Fema | 2017 |
Effectiveness of Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Conjunctiva; Dose-Response Relationship, Drug; Female; Fol | 2017 |
Recurrence rate of pterygium following surgical excision with intraoperative versus postoperative mitomycin-C.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Female; Humans; Intraoperative Period; Male; Midd | 2008 |
Intraoperative mitomycin C versus autologous conjunctival autograft in surgery of primary pterygium with four-year follow-up.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Conjunctiv | 2012 |
Preoperative subpterygeal injection vs intraoperative mitomycin C for pterygium removal: comparison of results and complications.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; F | 2010 |
Effects of mitomycin C on corneal endothelial cell counts in pterygium surgery: role of application location.
Topics: Adolescent; Adult; Alkylating Agents; Amnion; Cell Count; Combined Modality Therapy; Conjunctiva; Co | 2011 |
Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Amnion; Biological Dressings; Combined Modality T | 2011 |
Preoperative subpterygial mitomycin C injection versus limbal conjunctival autograft transplantation for prevention of pterygium recurrence.
Topics: Adult; Aged; Alkylating Agents; Conjunctiva; Female; Follow-Up Studies; Humans; Injections; Male; Mi | 2011 |
Randomized trial of pterygium surgery with mitomycin C application using conjunctival autograft versus conjunctival-limbal autograft.
Topics: Adult; Aged; Alkylating Agents; Chemotherapy, Adjuvant; Conjunctiva; Female; Follow-Up Studies; Huma | 2012 |
5-Fluorouracil versus mitomycin C as adjuncts to conjunctival autograft in preventing pterygium recurrence.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctiva; Female; Fluoro | 2012 |
Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery.
Topics: Adult; Antibiotics, Antineoplastic; Conjunctiva; Female; Follow-Up Studies; Humans; Injections; Intr | 2012 |
[Conjunctival limbal autograft versus simple excision with intra-operative mitomycin C in pterygium surgery: a comparative study].
Topics: Astigmatism; Conjunctiva; Female; Follow-Up Studies; Humans; Intraoperative Care; Male; Middle Aged; | 2013 |
[Study of intraoperative mitomycin C in preventing recurrence after pterygium surgery].
Topics: Adult; Conjunctiva; Female; Fibroblasts; Follow-Up Studies; Humans; Intraoperative Care; Male; Middl | 2001 |
Intraoperative mitomycin C 0.02% for pterygium: effect of duration of application on recurrence rate.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Humans; Intraoperative | 2003 |
Comparison of single-drop mitomycin C regime with other mitomycin C regimes in pterygium surgery.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Conjunctiva; Female; Humans; Intraoperative Care; Ma | 2003 |
Effect of pterygium surgery on corneal topography: a prospective study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Astigmatism; Combined Modality Therapy; Cornea; Corneal To | 2004 |
A randomised trial comparing 0.02% mitomycin C and limbal conjunctival autograft after excision of primary pterygium.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; H | 2004 |
Comparison of amniotic membrane graft alone or combined with intraoperative mitomycin C to prevent recurrence after excision of recurrent pterygia.
Topics: Adult; Aged; Aged, 80 and over; Amnion; Antibiotics, Antineoplastic; Biological Dressings; Combined | 2005 |
Preoperative injection of mitomycin C in combined pterygium and cataract surgery.
Topics: Cataract Extraction; Conjunctivitis, Allergic; Humans; Injections, Intralesional; Mitomycin; Preoper | 2005 |
Conjunctival autografting combined with low-dose mitomycin C for prevention of primary pterygium recurrence.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctiva; Female; Fibrosis; | 2006 |
Pterygium surgery with mitomycin and tarsorrhaphy.
Topics: Adult; Aged; Anti-Bacterial Agents; Dexamethasone; Drug Therapy, Combination; Eyelids; Female; Gluco | 2005 |
Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium.
Topics: Adult; Aged; Amnion; Chi-Square Distribution; Conjunctiva; Female; Humans; Limbus Corneae; Male; Mid | 2008 |
Comparison of limbal-conjunctival autograft and intraoperative 0.02% mitomycin-C for treatment of primary pterygium.
Topics: Adult; Conjunctiva; Corneal Transplantation; Female; Humans; Intraoperative Care; Limbus Corneae; Ma | 2007 |
Treatment of pterygium with conjunctival limbal autograft and mitomycin C--a comparative study.
Topics: Adult; Antibiotics, Antineoplastic; Conjunctiva; Disease Progression; Female; Humans; Male; Middle A | 2007 |
Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium.
Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Female; Follow-Up Studies; Humans; Intr | 1995 |
A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium.
Topics: Administration, Topical; Adult; Age Factors; Aged; Conjunctiva; Double-Blind Method; Female; Follow- | 1995 |
Effectiveness of intraoperative mitomycin C in the treatment of recurrent pterygium.
Topics: Adult; Drug Evaluation; Female; Follow-Up Studies; Humans; Intraoperative Care; Male; Middle Aged; M | 1994 |
Single dosage of mitomycin C for prevention of recurrent pterygium: preliminary report.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Double-Blind Method; Female; Follow-Up St | 1994 |
The use of low-dose mitomycin C for prevention of recurrent pterygium.
Topics: Administration, Topical; Adolescent; Adult; Double-Blind Method; Female; Follow-Up Studies; Humans; | 1994 |
Role of mitomycin C in pterygium surgery.
Topics: Adult; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Pterygium; Recu | 1993 |
Mitomycin C after pterygium excision.
Topics: Administration, Topical; Eye Diseases; Humans; Intraoperative Care; Mitomycin; Ophthalmic Solutions; | 1993 |
A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium.
Topics: Antibiotics, Antineoplastic; Conjunctiva; Humans; Mitomycin; Ophthalmic Solutions; Pterygium; Random | 1996 |
Intraoperative application of topical mitomycin C for pterygium surgery.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Double-Bl | 1996 |
Long term results of intraoperative mitomycin C in the treatment of recurrent pterygium.
Topics: Adult; Antibiotics, Antineoplastic; Case-Control Studies; Combined Modality Therapy; Female; Follow- | 1996 |
[Incidence of recurrence after primary pterygium excision, phototherapeutic keratectomy with the ArF:Excimer laser and local mitomycin C administration].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Follow-Up Studies; Huma | 1996 |
Intraoperative mitomycin-C versus postoperative topical mitomycin-C drops for the treatment of pterygium.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Female; F | 1996 |
Postoperative instillation of 0.04% mitomycin C in the treatment of primary pterygium in Zaire.
Topics: Antibiotics, Antineoplastic; Humans; Mitomycin; Ophthalmic Solutions; Postoperative Period; Pterygiu | 1996 |
Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery.
Topics: Adult; Antibiotics, Antineoplastic; Conjunctiva; Female; Follow-Up Studies; Humans; Intraoperative C | 1995 |
Intraoperative mitomycin in primary pterygium excision. A prospective, randomized trial.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Conjuncti | 1997 |
Intraoperative and postoperative use of mitomycin-C in the treatment of primary pterygium.
Topics: Administration, Topical; Chemotherapy, Adjuvant; Follow-Up Studies; Humans; Intraoperative Period; K | 1996 |
Topical mitomycin-C for pterygia: is single application appropriate?
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Female; F | 1997 |
Randomized trial of intraoperative mitomycin C in surgery for pterygium.
Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Double-Blind Method; Female; Follow-Up St | 1998 |
Application of mitomycin C 0.02% for 2 minutes at the end of pterygium surgery.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Follow-Up Studies; Humans; Middle Aged; Mitomycin; Pterygi | 1998 |
Conjunctival autograft versus topical mitomycin C in treatment of pterygium.
Topics: Adult; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Mitomycin; Nucleic Acid Synthesis Inhib | 1997 |
Intraoperative mitomycin C to prevent recurrence of pterygium after excision: a 30-month follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Double-Blind Method; | 1998 |
An improved surgical technique for pterygium excision with intraoperative application of mitomycin-C.
Topics: Adult; Chemotherapy, Adjuvant; Follow-Up Studies; Humans; Intraoperative Care; Middle Aged; Mitomyci | 1998 |
[A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results].
Topics: Administration, Topical; Adult; Aged; Alkylating Agents; Conjunctiva; Cost-Benefit Analysis; Drug Co | 1998 |
A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap.
Topics: Adult; Conjunctiva; Female; Follow-Up Studies; Humans; Limbus Corneae; Male; Middle Aged; Mitomycin; | 1999 |
Intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; | 1999 |
Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-Canadians.
Topics: Asia; Canada; Chemotherapy, Adjuvant; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle A | 1999 |
Intraoperative use of mitomycin C in the treatment of recurrent pterygium.
Topics: Adult; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Follow-Up Studies; Humans; In | 1998 |
Intraoperative mitomycin C in the treatment of pterygium.
Topics: Adult; Antibiotics, Antineoplastic; Female; Humans; Intraoperative Care; Male; Mitomycin; Ophthalmic | 2000 |
Low-dose intraoperative mitomycin C as chemoadjuvant for pterygium surgery.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Chemotherapy, Adjuvant; Conjunctiva; Female; Huma | 2001 |
Postoperative mitomycin-C eye drop and beta radiation in the treatment of pterygia.
Topics: Adult; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Mitomycin; Ophthalmic Solutions | 1991 |
150 other studies available for mitomycin and Pterygium
| Article | Year |
|---|---|
Outcomes of ipsilateral Simple Limbal Epithelial Transplantation, Tenonectomy, Mitomycin, and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium- Letter to editor.
Topics: Amnion; Humans; Limbus Corneae; Mitomycin; Pterygium | 2021 |
Author's Response to Letter: Outcomes of Ipsilateral Simple Limbal Epithelial Transplant (SLET), Mitomycin, Tenonectomy and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium.
Topics: Amnion; Humans; Limbus Corneae; Mitomycin; Pterygium | 2021 |
Comparison of surgical techniques for recurrent pterygium.
Topics: Adult; Conjunctiva; Follow-Up Studies; Humans; Mitomycin; Pterygium; Recurrence; Transplantation, Au | 2023 |
Cryopreserved Amniotic Membrane Using the TissueTuck Technique: A Sutureless Approach for Pterygium Surgery.
Topics: Amnion; Conjunctiva; Female; Follow-Up Studies; Humans; Mitomycin; Pterygium; Recurrence; Treatment | 2023 |
Outcomes of the TissueTuck Surgical Technique for Recurrent Pterygium.
Topics: Aged; Conjunctiva; Follow-Up Studies; Humans; Middle Aged; Mitomycin; Pterygium; Recurrence; Treatme | 2024 |
Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report.
Topics: Aged, 80 and over; Cataract Extraction; Female; Glaucoma; Humans; Mitomycin; Postoperative Complicat | 2023 |
[Outcome of pterygium excision after various surgical techniques-is excision with simple conjunctival closure still lege artis?]
Topics: Conjunctiva; Female; Follow-Up Studies; Humans; Male; Mitomycin; Pterygium; Recurrence; Retrospectiv | 2020 |
[The use of mitomycin C in pterygium surgery].
Topics: Conjunctiva; Eyelids; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Pterygium | 2020 |
[Should mitomycin C be used routinely in pterygium surgery?]
Topics: Conjunctiva; Eyelids; Follow-Up Studies; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Pter | 2020 |
Antifibrotic Effects of Sakuraso-Saponin in Primary Cultured Pterygium Fibroblasts in Comparison With Mitomycin C.
Topics: Actins; Alkylating Agents; Blotting, Western; Cell Movement; Cell Survival; Cells, Cultured; Fibrobl | 2019 |
Comment on "Interferon Alpha-2b Eye Drops Prevent Recurrence of Pterygium After the Bare Scleral Technique: A Single-Center, Sequential, and Controlled Study".
Topics: Conjunctiva; Humans; Interferon-alpha; Mitomycin; Ophthalmic Solutions; Pterygium; Sclera | 2020 |
Outcomes of Ipsilateral Simple Limbal Epithelial Transplantation, Tenonectomy, Mitomycin and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium.
Topics: Adult; Aged; Alkylating Agents; Amnion; Epithelium, Corneal; Female; Follow-Up Studies; Humans; Limb | 2021 |
Role of oxidative stress and vascular endothelial growth factor expression in pterygium pathogenesis and prevention of pterygium recurrence after surgical excision.
Topics: Conjunctiva; Humans; Mitomycin; Oxidative Stress; Pterygium; Recurrence; Transplantation, Autologous | 2020 |
Targeted delivery of mitomycin C-loaded and LDL-conjugated mesoporous silica nanoparticles for inhibiting the proliferation of pterygium subconjunctival fibroblasts.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Conjunctiva; Cross-Linking Reagents; Drug Delive | 2020 |
[Lamellar keratoplasty in the management of recurrent pterygium].
Topics: Conjunctiva; Corneal Diseases; Corneal Transplantation; Humans; Mitomycin; Pterygium | 2020 |
Pterygium excision with modified bare sclera technique combined with mitomycin C.
Topics: Conjunctiva; Follow-Up Studies; Humans; Mitomycin; Pterygium; Recurrence; Retrospective Studies; Scl | 2021 |
[Pterygium: pathogenesis, diagnosis and treatment].
Topics: Astigmatism; Conjunctiva; Humans; Mitomycin; Pterygium; Recurrence; Transplantation, Autologous | 2021 |
Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.
Topics: Adult; Aged; Conjunctiva; Follow-Up Studies; Humans; Middle Aged; Mitomycin; Pterygium; Recurrence; | 2021 |
Effect of Vitamin D3 on Regulating Human Tenon's Fibroblasts Activity.
Topics: Cells, Cultured; Cholecalciferol; Fibroblasts; Humans; Mitomycin; Pterygium | 2021 |
Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy.
Topics: Alkylating Agents; Biomarkers; Cell Movement; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; | 2017 |
Systemic Absorption of Mitomycin-C When Used in Pterygium Surgery.
Topics: Adult; Alkylating Agents; Female; Humans; Male; Middle Aged; Mitomycin; Ophthalmic Solutions; Ophtha | 2018 |
Cellular Proliferation and Migration of Human Pterygium Cells: Mitomycin Versus Small-Molecule Inhibitors.
Topics: Analysis of Variance; Apoptosis; Cell Line; Cell Movement; Cell Proliferation; Conjunctiva; Cyclin-D | 2018 |
Novel grid and sectoral analyses in monitoring corneal scars.
Topics: Adult; Aged; Alkylating Agents; Analysis of Variance; Cicatrix; Cornea; Corneal Injuries; Densitomet | 2019 |
The Evolving Story of Pterygium.
Topics: Amnion; Combined Modality Therapy; Conjunctiva; Humans; Mitomycin; Proto-Oncogene Proteins c-mdm2; P | 2018 |
Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft.
Topics: Administration, Topical; Adult; Age Distribution; Aged; Alkylating Agents; Conjunctiva; Female; Foll | 2013 |
Pre-operative sub-conjunctival mitomycin C 24 hours before excision of recurrent pterygium.
Topics: Female; Humans; Intraoperative Care; Male; Mitomycin; Ophthalmologic Surgical Procedures; Preoperati | 2013 |
Other considerations in pterygium surgery.
Topics: Alkylating Agents; Amnion; Conjunctiva; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Ptery | 2013 |
Author reply: To PMID 23062647.
Topics: Alkylating Agents; Amnion; Conjunctiva; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Ptery | 2013 |
Liquid nitrogen cryotherapy of pterygia.
Topics: Alkylating Agents; Amnion; Conjunctiva; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Ptery | 2013 |
Author reply: To PMID 23062647.
Topics: Alkylating Agents; Amnion; Conjunctiva; Humans; Mitomycin; Ophthalmologic Surgical Procedures; Ptery | 2013 |
[Pterygium excision using bulbar conjunctival autograft with intraoperative mitomycin C for primary pterygium: a retrospective assessment of 1832 eyes].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autografts; Child; Conjunctiva; Female; Humans; Intraope | 2013 |
[Mitomycin C related complications shouldn't be neglected in the pterygium surgery].
Topics: Contraindications; Humans; Mitomycin; Postoperative Complications; Pterygium | 2013 |
Dexamethasone modifies mitomycin C-triggered interleukin-8 secretion in isolated human Tenon's capsule fibroblasts.
Topics: Apoptosis; bcl-X Protein; Blotting, Western; Cell Proliferation; Cells, Cultured; Dexamethasone; Enz | 2014 |
Threshold to predict astigmatism reduction after pterygium excision.
Topics: Adult; Aged; Alkylating Agents; Astigmatism; Conjunctiva; Cornea; Female; Humans; Male; Middle Aged; | 2014 |
Subconjunctival bevacizumab injection in the surgery of primary pterygium: comparison with intraoperative mitomycin-C.
Topics: Alkylating Agents; Antibodies, Monoclonal, Humanized; Bevacizumab; Conjunctiva; Female; Humans; Inje | 2013 |
Long-term clinical outcomes of conjunctival flap surgery for calcified scleromalacia after periocular surgery.
Topics: Adult; Calcinosis; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Oph | 2015 |
Comparison of intra-operative 0.02% mitomycin C and sutureless limbal conjunctival autograft fixation in pterygium surgery: five-year follow-up.
Topics: Adult; Aged; Alkylating Agents; Autografts; Conjunctiva; Female; Fibrin Tissue Adhesive; Follow-Up S | 2015 |
Mitomycin C-associated scleral stromalysis after pterygium surgery.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Chemotherapy, Adjuvant; Female; Humans; Male; Mid | 2015 |
Monitoring corneal densities following primary pterygium excision with adjuvant topical mitomycin-C application--an observational study of corneal scar changes.
Topics: Adult; Aged; Alkylating Agents; Cell Count; Combined Modality Therapy; Cornea; Female; Humans; Intra | 2015 |
Combined conjunctival rotational autograft with 0.02% mitomycin C in primary pterygium surgery: a long-term follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Autografts; Conjunctiva; Female; Follow-Up Studie | 2015 |
The results of pterygium excision at Thammasat Hospital.
Topics: Adult; Aged; Aged, 80 and over; Amnion; Antibiotics, Antineoplastic; Female; Granulation Tissue; Hum | 2015 |
Conjunctival Short-term Evolution after Pterygium Excision.
Topics: Adult; Aged; Alkylating Agents; Cell Count; Conjunctiva; Epithelial Cells; Female; Goblet Cells; Hum | 2015 |
Scleral patch graft in the management of necrotising scleritis with inflammation. A case report.
Topics: Allografts; Amnion; Female; Humans; Middle Aged; Mitomycin; Necrosis; Postoperative Complications; P | 2016 |
Long-Term Density Changes in Corneal Layers After Primary Pterygium Excision With Topical Mitomycin-C.
Topics: Administration, Topical; Aged; Alkylating Agents; Cell Count; Combined Modality Therapy; Cornea; Den | 2016 |
Intraoperative application of 5-fluorouracil and mitomycin C aschemoadjuvants in primary pterygium surgery.
Topics: Fluorouracil; Follow-Up Studies; Humans; Intraoperative Care; Mitomycin; Prospective Studies; Pteryg | 2016 |
Effect of mitomycin C in pterygium surgery on corneal endothelium.
Topics: Alkylating Agents; Cell Count; Combined Modality Therapy; Endothelium, Corneal; Female; Humans; Male | 2008 |
Comparison of mini-flap technique and conjunctival autograft transplantation without mitomycin C in primary and recurrent pterygium.
Topics: Alkylating Agents; Conjunctiva; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Pte | 2008 |
Corneal and conjunctival findings after mitomycin C application in pterygium surgery: an in-vivo confocal microscopy study.
Topics: Administration, Topical; Adult; Aged; Conjunctiva; Cornea; Corneal Edema; Drug Administration Schedu | 2009 |
Conjunctival autograft failure in eyes previously exposed to beta-radiation or mitomycin.
Topics: Conjunctiva; Female; Follow-Up Studies; Graft Rejection; Humans; Male; Mitomycin; Nose; Pterygium; R | 2008 |
The effect of mitomycin C on corneal endothelium in pterygium surgery.
Topics: Adult; Aged; Alkylating Agents; Cell Count; Combined Modality Therapy; Conjunctiva; Endothelium, Cor | 2009 |
Efficacy and safety of intraoperative mitomycin C as adjunct therapy for pterygium surgery.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Intraocular Pressure; Intraoperative Care; Male; Mid | 2008 |
Medical management of acutely recurring pterygium with topical mitomycin-C.
Topics: Acute Disease; Administration, Topical; Adult; Alkylating Agents; Female; Humans; Male; Middle Aged; | 2009 |
Prospective study on the safety and efficacy of combined conjunctival rotational autograft with intraoperative 0.02% mitomycin C in primary pterygium excision.
Topics: Administration, Topical; Adult; Aged; Alkylating Agents; Conjunctiva; Female; Humans; Intraoperative | 2009 |
Endothelial cell loss during pterygium surgery: importance of timing of mitomycin C application.
Topics: Adult; Antimitotic Agents; Cell Count; Cell Death; Drug Administration Schedule; Endothelium, Cornea | 2009 |
Pulse-mode mitomycin C use in pterygium surgery.
Topics: Alkylating Agents; Cell Count; Combined Modality Therapy; Conjunctiva; Endothelium, Corneal; Fibrin | 2009 |
Intraoperative mitomycin C and corneal endothelium after pterygium surgery.
Topics: Adult; Aged; Aged, 80 and over; Cell Count; Cell Shape; Cell Size; Endothelium, Corneal; Female; Fol | 2009 |
Atomic force microscope-related study membrane-associated cytotoxicity in human pterygium fibroblasts induced by mitomycin C.
Topics: Apoptosis; Calcium; Cell Membrane; Elasticity; Fibroblasts; Humans; Lactate Dehydrogenases; Lipid Pe | 2010 |
Effectiveness of intra-operative Mitomycin-C in reducing the recurrence of pterygium in Irrua, Nigeria.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Alkylating Agents; Antibiotics, Antineoplastic; Fe | 2010 |
[Pterygium. Etiology, clinical aspects and novel adjuvant therapies].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibod | 2010 |
Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation.
Topics: Adult; Amnion; Combined Modality Therapy; Conjunctiva; Female; Humans; Injections, Intravenous; Meth | 2010 |
[Endothelial cells analysis after intraoperative mitomycin-C adjuvant pterygium simple excision surgery: a pilot study].
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Endothelial Cel | 2010 |
[Clinical observation of therapeutic efficacy and study of conjunctival impression cytology after pterygium surgery].
Topics: Aged; Conjunctiva; Cytodiagnosis; Cytological Techniques; Female; Humans; Male; Middle Aged; Mitomyc | 2010 |
Mycophenolic acid suppresses human pterygium and normal tenon fibroblast proliferation in vitro.
Topics: Adult; Aged; Analysis of Variance; Apoptosis; Cell Proliferation; Cells, Cultured; Dexamethasone; Do | 2010 |
Preoperative subpterygeal mitomycin C injection.
Topics: Alkylating Agents; Combined Modality Therapy; Conjunctiva; Humans; Injections; Intraoperative Care; | 2010 |
Preoperative subpterygeal injection versus intraoperative mitomycin C for pterygium removal: comparison of results and complications.
Topics: Alkylating Agents; Combined Modality Therapy; Conjunctiva; Humans; Injections; Intraoperative Care; | 2011 |
Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue.
Topics: Adult; Aged; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; Fibrin Tissue Adhesi | 2011 |
Sodium hyaluronate gel as mitomycin C vehicle to reduce potential endothelial toxicity in pterygium surgery.
Topics: Antimitotic Agents; Endothelium, Corneal; Female; Humans; Male; Mitomycin; Nucleic Acid Synthesis In | 2011 |
[Necrotizing scleritis after pterygium surgery using mitomycin C].
Topics: Antibiotics, Antineoplastic; Female; Humans; Intraoperative Care; Middle Aged; Mitomycin; Ophthalmol | 2012 |
New grading system to improve the surgical outcome of multirecurrent pterygia.
Topics: Adult; Aged; Amnion; Biological Dressings; Conjunctiva; Female; Follow-Up Studies; Humans; Intraoper | 2012 |
Scleral melting secondary to surgical excision of a pterygium augmented with mitomycine C application.
Topics: Aged; Female; Humans; Mitomycin; Necrosis; Postoperative Complications; Pterygium; Sclera; Scleral D | 2012 |
Pterygium recurrence related to its size and corneal involvement.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Alkylating Agents; Conjunctiva; Cornea | 2013 |
Scleral ulceration after preoperative injection of mitomycin C in the pterygium head.
Topics: Alkylating Agents; Bacitracin; Humans; Injections, Intralesional; Male; Middle Aged; Mitomycin; Oint | 2002 |
Surgical treatment of chronically recurring pterygium.
Topics: Adult; Amnion; Antibiotics, Antineoplastic; Conjunctiva; Humans; Intraoperative Care; Male; Mitomyci | 2003 |
Surgical management of pterygium.
Topics: Conjunctiva; Humans; Mitomycin; Nucleic Acid Synthesis Inhibitors; Pterygium; Recurrence; Transplant | 2002 |
Subconjunctival mitomycin C as adjunctive therapy before pterygium excision.
Topics: Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Conjunctiva; Female; Follow-Up Studies; | 2003 |
Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery.
Topics: Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Corneal Transplantation; Female; Graft | 2003 |
[Outcome of surgery for recurrent pterygium using intraoperative application of mitomycin C and amniotic membrane transplantation].
Topics: Adult; Aged; Amnion; Female; Humans; Intraoperative Care; Male; Middle Aged; Mitomycin; Pterygium; R | 2003 |
Outcome of double-headed pterygium surgery.
Topics: Adult; Aged; Female; Granuloma, Pyogenic; Humans; Intraoperative Care; Male; Middle Aged; Mitomycin; | 2003 |
Combined mitomycin C application and free flap conjunctival autograft in pterygium surgery.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Drug Administration Schedule; Humans; Intraoperative Pe | 2003 |
Pterygium surgery with mitomycin C: how much sclera should be left bare?
Topics: Administration, Topical; Adult; Conjunctiva; Drug Administration Schedule; Esthetics; Female; Humans | 2003 |
Mitomycin C and pterygium excision.
Topics: Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Conjunctiva; Humans; Injections, Intralesional; | 2003 |
Intraoperative mitomycin C 0.02% for pterygium.
Topics: Antibiotics, Antineoplastic; Combined Modality Therapy; Humans; Intraoperative Care; Mitomycin; Pter | 2004 |
Long-term effects of mitomycin C in pterygium surgery on scleral thickness and the conjunctival epithelium.
Topics: Adult; Alkylating Agents; Cell Count; Conjunctiva; Epithelium; Female; Goblet Cells; Humans; Male; M | 2004 |
[Application of amnion membrane transplantation combine with mitomycin C in the treatment of pterygium].
Topics: Adult; Aged; Amnion; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Pterygium; Sec | 2004 |
Mitomycin C for pterygium: long term evaluation.
Topics: Adult; Aged; Alkylating Agents; Antibiotics, Antineoplastic; Conjunctiva; Female; Humans; Intraopera | 2004 |
Combined mitomycin C application and free flap conjunctival autograft in pterygium surgery.
Topics: Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctiva; Humans; Mitomycin; Pterygium; S | 2004 |
Outcome of pterygium surgery: analysis over 14 years.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amnion; Chemotherapy, Adjuvant; Child; Child, Preschool; | 2005 |
Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C.
Topics: Corneal Diseases; Eye Diseases; Follow-Up Studies; Granuloma; Humans; Laser Therapy; Lasers, Excimer | 2005 |
Safety and efficacy of the technique of complete tenon's membrane excision and mitomycin C in pterygium surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Combined Modal | 2005 |
Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium.
Topics: Aged; Amnion; Antibiotics, Antineoplastic; Cell Transplantation; Combined Modality Therapy; Epitheli | 2005 |
Mitomycin C, amniotic membrane transplantation and limbal conjunctival autograft for treating multirecurrent pterygia with symblepharon and motility restriction.
Topics: Adult; Alkylating Agents; Amnion; Cell Transplantation; Combined Modality Therapy; Conjunctiva; Conj | 2006 |
Scedosporium prolificans sclerokeratitis 10 years after pterygium excision with adjunctive mitomycin C.
Topics: Amphotericin B; Antibiotics, Antineoplastic; Antifungal Agents; Chemotherapy, Adjuvant; Drug Therapy | 2005 |
Mitomycin C in the treatment of pterygium.
Topics: Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctiva; Humans; Mitomycin; Pterygium; S | 2006 |
Combined "symmetrical conjunctival flap transposition" and intraoperative low-dose mitomycin C in the treatment of primary pterygium.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Conjun | 2006 |
Novel clinical application of sterilized, freeze-dried amniotic membrane to treat patients with pterygium.
Topics: Adult; Aged; Amnion; Conjunctiva; Epithelium; Female; Fibrosis; Freeze Drying; Humans; Male; Middle | 2006 |
Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapy.
Topics: Humans; Male; Middle Aged; Mitomycin; Nucleic Acid Synthesis Inhibitors; Ophthalmic Solutions; Ophth | 2006 |
Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C.
Topics: Adult; Alkylating Agents; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Lasers, Exci | 2006 |
Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C.
Topics: Alkylating Agents; Combined Modality Therapy; Follow-Up Studies; Humans; Lasers, Excimer; Mitomycin; | 2006 |
[Clinical study in combining application of mitomycin and amnion transplantation together with pterygium resection].
Topics: Aged; Amnion; Cross-Linking Reagents; Female; Humans; Male; Middle Aged; Mitomycin; Postoperative Co | 2005 |
Clinical outcome study of a modified surgical technique for pterygium excision.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctiva; Female; Follow-Up Studies; | 2006 |
Conjunctival flaps for pterygium surgery.
Topics: Chemotherapy, Adjuvant; Conjunctiva; Fluorouracil; Humans; Mitomycin; Ophthalmologic Surgical Proced | 2006 |
Mitomycin C and conjunctival autograft for recurrent pterygium.
Topics: Adult; Aged; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; Humans; Male; Middle | 2007 |
Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C.
Topics: Administration, Topical; Adolescent; Adult; Aged; Amnion; Analysis of Variance; Antibiotics, Antineo | 2007 |
Efficacy of mitomycin C associated with direct conjunctival closure and sliding conjunctival graft for pterygium surgery.
Topics: Adult; Aged; Conjunctiva; Female; Humans; Intraoperative Care; Male; Middle Aged; Mitomycin; Nucleic | 2008 |
Conjunctival-limbal autograft, amniotic membrane transplantation, and intraoperative mitomycin C for primary pterygium.
Topics: Adolescent; Adult; Aged; Amnion; Conjunctiva; Corneal Transplantation; Female; Humans; Intraoperativ | 2007 |
Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium.
Topics: Adult; Aged; Aged, 80 and over; Amnion; Conjunctivitis; Female; Fibrin Tissue Adhesive; Follow-Up St | 2008 |
Corneal topographic changes after four types of pterygium surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astigmatism; Conjunctiva; Cornea; Corneal Topography; Fe | 2008 |
Subconjunctival mitomycin C before pterygium excision: an ultrastructural study.
Topics: Aged; Alkylating Agents; Conjunctiva; Epithelial Cells; Female; Fibroblasts; Humans; Injections; Mal | 2008 |
[Pterygium excision with intra-operative administration of low dosage mitomycin C].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Dose-Response Relationship, Dru | 1995 |
Prevention of pterygium recurrence: conjunctival grafts vs. mitomycin C.
Topics: Conjunctiva; Humans; Mitomycin; Ophthalmic Solutions; Pterygium; Recurrence; Transplantation, Autolo | 1995 |
Prevention of pterygium recurrence: conjunctival grafts vs. mitomycin C.
Topics: Conjunctiva; Humans; Mitomycin; Ophthalmic Solutions; Pterygium; Transplantation, Autologous | 1995 |
Results of treatment with topical mitomycin C 0.02% following excision of primary pterygium.
Topics: Administration, Topical; Adult; Aged; Dexamethasone; Drug Therapy, Combination; Female; Follow-Up St | 1995 |
Corneoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy.
Topics: Administration, Topical; Aged; Corneal Ulcer; Female; Humans; Mitomycin; Ophthalmic Solutions; Posto | 1993 |
Mitomycin-C after pterygium excision.
Topics: Eye Diseases; Humans; Mitomycin; Ophthalmic Solutions; Postoperative Care; Pterygium; Recurrence | 1993 |
Mitomycin-C after pterygium excision.
Topics: Eye Diseases; Humans; Intraoperative Care; Mitomycin; Ophthalmic Solutions; Postoperative Care; Pter | 1993 |
Scleral changes due to mitomycin C after pterygium excision: a report of two cases.
Topics: Adult; Antibiotics, Antineoplastic; Calcinosis; Chemotherapy, Adjuvant; Humans; Male; Middle Aged; M | 1995 |
Indications for and complications of mitomycin-C in pterygium surgery.
Topics: Adolescent; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Conjunct | 1996 |
Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C.
Topics: Chemotherapy, Adjuvant; Contraindications; Corneal Diseases; Eye Injuries, Penetrating; Humans; Intr | 1996 |
[Effect of local administration of mitomycin C on intraocular pressure].
Topics: Adult; Aged; Female; Humans; Intraocular Pressure; Male; Middle Aged; Mitomycin; Ophthalmic Solution | 1996 |
Topical mitomycin C for pterygium surgery.
Topics: Administration, Topical; Humans; Intraoperative Care; Mitomycin; Pterygium; Recurrence | 1997 |
Intraoperative mitomycin in primary pterygium excision.
Topics: Antibiotics, Antineoplastic; Conjunctiva; Humans; Intraoperative Care; Mitomycin; Pterygium; Transpl | 1998 |
Intraoperative mitomycin in primary pterygium excision.
Topics: Antibiotics, Antineoplastic; Humans; Intraoperative Care; Mitomycin; Pterygium; Recurrence | 1998 |
[Treatment of recurrent pterygia].
Topics: Combined Modality Therapy; Humans; Mitomycin; Pterygium; Recurrence | 1997 |
Intrascleral dissemination of infectious scleritis following pterygium excision.
Topics: Abscess; Adult; Aged; Antibiotics, Antineoplastic; Eye Infections, Bacterial; Female; Follow-Up Stud | 1998 |
Randomized trial of intraoperative mitomycin C in surgery for pterygium.
Topics: Humans; Intraoperative Care; Mitomycin; Pterygium; Randomized Controlled Trials as Topic | 1998 |
Single application mitomycin C in primary pterygium surgery.
Topics: Adult; Aged; Astigmatism; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Ophthalmi | 1998 |
Intraoperative mitomycin C for pterygium surgery.
Topics: Cell Division; Chemotherapy, Adjuvant; Fibroblasts; Humans; Intraoperative Care; Mitomycin; Ophthalm | 1999 |
Randomized trial of intraoperative mitomycin C in surgery for pterygium.
Topics: Chemotherapy, Adjuvant; Humans; Intraoperative Care; Mitomycin; Pterygium; Randomized Controlled Tri | 1999 |
Ophthaproblem. Pterygium.
Topics: Adult; Antibiotics, Antineoplastic; Conjunctiva; Diagnosis, Differential; Humans; Male; Mitomycin; P | 1999 |
Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery.
Topics: Adult; Aged; Beta Particles; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Male; Middle | 2000 |
Amniotic membrane graft for primary pterygium: comparison with conjunctival autograft and topical mitomycin C treatment.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Amnion; Analysis of Variance; Antibiotics, | 2000 |
Late complications after pterygium excision with high dose mitomycin C instillation.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Female; Humans; Mitomycin; Postoperative Compl | 2000 |
Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery.
Topics: Adult; Beta Particles; Combined Modality Therapy; Follow-Up Studies; Humans; Male; Middle Aged; Mito | 2001 |
[Mitomycin C and pterygium resection].
Topics: Humans; Mitomycin; Pterygium | 2000 |
Results of intra-operative 0.5mg/ml mitomycin C with 20mg depo steroid in the treatment of primary pterygium.
Topics: Adult; Aged; Anti-Inflammatory Agents; Combined Modality Therapy; Delayed-Action Preparations; Drug | 2000 |
Measures for preventing recurrence after pterygium surgery.
Topics: Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Mitomycin; Ophthalmologic Surgical Proce | 2001 |
Review of treatment of pterygium in Queensland: 10 years after a primary survey.
Topics: Anesthesia, Local; Chemotherapy, Adjuvant; Conjunctiva; Health Surveys; Humans; Mitomycin; Ophthalmo | 2001 |
[Peroperative use of mitomycin C in excision of primary pterygia].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Female; Humans; Intraoperative Period; Male; Middle Aged; | 2001 |
Serious corneoscleral complications after pterygium excision with mitomycin C.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Corneal Diseases; Humans; Male; Middle Aged; Mitomycin; Po | 2002 |
Corneoscleral, ciliary body, and vitreoretinal toxicity after excessive instillation of mitomycin C.
Topics: Adult; Ciliary Body; Corneal Diseases; Eye Diseases; Female; Humans; Mitomycin; Pterygium; Retinal D | 1992 |
Who should receive mitomycin-C after pterygium surgery?
Topics: Eye Diseases; Humans; Mitomycin; Postoperative Complications; Pterygium; Recurrence | 1992 |
Serious complications of topical mitomycin-C after pterygium surgery.
Topics: Adult; Aged; Calcinosis; Cataract; Contraindications; Corneal Diseases; Eye Diseases; Female; Humans | 1992 |
Pterygium excision using 193-nm excimer laser smoothing and topical mitomycin C.
Topics: Female; Follow-Up Studies; Humans; Laser Therapy; Male; Middle Aged; Mitomycin; Ophthalmic Solutions | 1992 |
[Local mitomycin C therapy after excision of pterygium].
Topics: Combined Modality Therapy; Drug Administration Schedule; Humans; Mitomycin; Ophthalmic Solutions; Pt | 1992 |
Corneal melting after pterygium removal followed by topical mitomycin C therapy.
Topics: Administration, Topical; Aged; Cornea; Humans; Keratoplasty, Penetrating; Male; Mitomycin; Necrosis; | 1992 |
Mitomycin in treating pterygium.
Topics: Humans; Mitomycin; Mitomycins; Ophthalmic Solutions; Pterygium | 1989 |
Postoperative instillation of low-dose mitomycin C in the treatment of primary pterygium.
Topics: Combined Modality Therapy; Humans; Mitomycin; Mitomycins; Ophthalmic Solutions; Postoperative Care; | 1989 |
Postoperative instillation of mitomycin C in the treatment of recurrent pterygium.
Topics: Conjunctival Diseases; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Mitomycin; Mi | 1989 |
Prevention of recurrent pterygium by mitomycin-C.
Topics: Combined Modality Therapy; Humans; Mitomycin; Mitomycins; Ophthalmic Solutions; Pterygium; Recurrenc | 1987 |
Postoperative instillation of low-dose mitomycin C in the treatment of primary pterygium.
Topics: Drug Administration Schedule; Humans; Mitomycin; Mitomycins; Ophthalmic Solutions; Postoperative Car | 1988 |