mitomycin has been researched along with Primary Ovarian Insufficiency in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, Y | 1 |
| Yang, X | 1 |
| Zhang, F | 1 |
| Chen, S | 1 |
| Zhou, Z | 1 |
| Yin, H | 1 |
| Ma, H | 1 |
| Shang, L | 1 |
| Yang, J | 1 |
| Li, G | 1 |
| Wang, Y | 1 |
| Jin, L | 1 |
| Shi, Q | 1 |
| Wu, Y | 1 |
| Xu, X | 1 |
| Zhang, Y | 1 |
| Zhao, S | 1 |
| Bian, Y | 1 |
| Ning, Y | 1 |
| Qin, Y | 1 |
2 other studies available for mitomycin and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
Topics: Alkylating Agents; Animals; Base Sequence; Disease Models, Animal; DNA Repair; Embryo, Mammalian; Fa | 2021 |
Mutational analysis of theFAM175A gene in patients with premature ovarian insufficiency.
Topics: Adult; BRCA1 Protein; Carrier Proteins; DNA Damage; DNA Mutational Analysis; DNA Repair; Female; Gen | 2019 |