mitomycin has been researched along with Pregnancy in 56 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Significant pregnancy-specific alterations in drug disposition, including higher plasma concentrations and decreased clearances in pregnant animals, highlight the need for drug-level monitoring and possible dosage modification when these agents are used in pregnancy." | 5.28 | Chemotherapy in a pregnant rat model. 1. Mitomycin-C: pregnancy-specific kinetics and placental transfer. ( Boike, GM; Bottoms, SF; Deppe, G; Gove, NL; Malone, JM; Malviya, VK; Sokol, RJ; Young, JD, 1989) |
| "However, on day 9, no exencephaly was produced, and there was a drastic reduction in the number of tail and spinal defects, the overall incidence of NTD being as low as 15% with 2 mg/kg." | 5.27 | Effect of mitomycin C on the neural tube defects of the curly-tail mouse. ( Perkins, KJ; Seller, MJ, 1986) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Anal cancer was diagnosed in a 36-year-old nulliparous woman." | 1.43 | Successful Delivery in a 39-Year-Old Patient with Anal Cancer after Fertility-Preserving Surgery Followed by Primary Chemoradiation and Low Anti-Mullerian Hormone Level. ( Biel, P; Cordes, T; Köhler, C; Marnitz, S, 2016) |
| "One of the key obstacles against the success in cancer chemotherapy is the toxic and side effects of the chemotherapeutic agents." | 1.36 | Using activated carbon nanoparticles to decrease the genotoxicity and teratogenicity of anticancer therapeutic agents. ( Shuzheng, M; Yingge, Z; Zhong, Y, 2010) |
| "Pretreatment with retrorsine crosslinks host hepatocyte DNA and prevents proliferation after partial hepatectomy (PH), allowing selective expansion of transplanted progenitors." | 1.35 | Engraftment of syngeneic and allogeneic endothelial cells, hepatocytes and cholangiocytes into partially hepatectomized rats previously treated with mitomycin C. ( Brilliant, KE; Callanan, HM; Hixson, DC; Mills, DR, 2009) |
| "The standard therapy for invasive uterine cervical cancer causes loss of the woman's fertility." | 1.33 | A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization. ( Akiyama, F; Hasumi, K; Kobayashi, Y, 2006) |
| "We examined 159 patients with thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan." | 1.30 | Outcome of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan. ( Ihara, T; Kakisita, E; Minami, N; Mori, Y; Omine, M; Shiku, H; Tamaki, S; Wada, H, 1999) |
| "This entity of severe intrauterine growth retardation and increased mitomycin C sensitivity is hypothesised to be a distinct chromosome breakage syndrome." | 1.29 | Severe intrauterine growth retardation with increased mitomycin C sensitivity: a further chromosome breakage syndrome. ( Leversha, M; Rogers, JG; Woods, CG, 1995) |
| " The toxic activity of MMC in mouse bone marrow was significantly reduced or completely abolished after its inclusion in PBCN." | 1.28 | Diminished genotoxicity of mitomycin C and farmorubicin included in polybutylcyanoacrylate nanoparticles. ( Balansky, RM; Blagoeva, PM; Mircheva, TJ; Simeonova, MI, 1992) |
| "Of the 15 patients who developed brain metastases after prior chemotherapy, 12 had received MAC at least once prior to the diagnosis of brain metastases, and in 5 patients, MAC was the first chemotherapy given after the diagnosis of brain metastases." | 1.28 | Intracerebral choriocarcinoma. ( Jones, WB; Lewis, JL; Wagner-Reiss, KM, 1990) |
| " Significant pregnancy-specific alterations in drug disposition, including higher plasma concentrations and decreased clearances in pregnant animals, highlight the need for drug-level monitoring and possible dosage modification when these agents are used in pregnancy." | 1.28 | Chemotherapy in a pregnant rat model. 1. Mitomycin-C: pregnancy-specific kinetics and placental transfer. ( Boike, GM; Bottoms, SF; Deppe, G; Gove, NL; Malone, JM; Malviya, VK; Sokol, RJ; Young, JD, 1989) |
| " Time-response and dose-response were studied for chromosomal aberrations induced by transplacental treatment of mouse embryos." | 1.27 | New approaches to mutagenicity studies in animals for carcinogenic and mutagenic agents. II. Clastogenic effects determined in transplacentally treated mouse embryos. ( Adler, ID, 1983) |
| "Mitomycin C was slightly less effective in foetal liver than in maternal bone marrow." | 1.27 | Sister-chromatid exchange and micronucleus induction as indicators of genetic damage in maternal and foetal cells. ( Aghamohammadi, Z; Cole, H; Cole, J; Cole, R; Henderson, L; Regan, T, 1984) |
| " This new testing system appears to be a sensitive method of measuring the direct effects of toxic chemicals which yields results in a short term." | 1.27 | Toxic effects of chemicals on mouse post-blastocyst development--a trial to establish a testing system for embryotoxicity. ( Katayama, S; Matsumoto, N, 1985) |
| "However, on day 9, no exencephaly was produced, and there was a drastic reduction in the number of tail and spinal defects, the overall incidence of NTD being as low as 15% with 2 mg/kg." | 1.27 | Effect of mitomycin C on the neural tube defects of the curly-tail mouse. ( Perkins, KJ; Seller, MJ, 1986) |
| "When mitomycin-C treatment alone was performed on day 9." | 1.27 | Teratogenic interactions between methylmercury and mitomycin-C in mice. ( Inouye, M; Kajiwara, Y, 1988) |
| "The mitomycin-treated blastocysts with only 70% of normal ICM cells developed to egg cylinders that were about half normal size, but by days 12-14 the body size of the surviving embryo was similar to that of the control embryo." | 1.27 | Postimplantation development of mitomycin C-treated mouse blastocysts. ( Tam, PP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (41.07) | 18.7374 |
| 1990's | 10 (17.86) | 18.2507 |
| 2000's | 6 (10.71) | 29.6817 |
| 2010's | 14 (25.00) | 24.3611 |
| 2020's | 3 (5.36) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, L | 1 |
| Shi, J | 1 |
| Feng, J | 1 |
| Zhang, P | 1 |
| Ren, Y | 1 |
| Chen, R | 1 |
| Kou, ZQ | 1 |
| Wang, XR | 1 |
| Li, SH | 1 |
| Zhang, HL | 1 |
| Liu, ZW | 1 |
| Cheng, D | 1 |
| Wang, ZY | 1 |
| Yu, XJ | 1 |
| Wen, HL | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Ghobakhloo, N | 1 |
| Sutton, R | 1 |
| Ambrosio, L | 1 |
| Meng, X | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
| Moura, MT | 1 |
| Sousa, RV | 1 |
| Lucci, CM | 1 |
| Rumpf, R | 1 |
| Burgazli, KM | 1 |
| Mericliler, M | 1 |
| Kavukcu, E | 1 |
| Erdogan, A | 1 |
| Ertan, AK | 1 |
| Laussu, J | 1 |
| Khuong, A | 1 |
| Gautrais, J | 1 |
| Davy, A | 1 |
| Köhler, C | 1 |
| Marnitz, S | 1 |
| Biel, P | 1 |
| Cordes, T | 1 |
| Sanders, JA | 1 |
| Karimi, H | 1 |
| Mahdavi, P | 1 |
| Fakhari, S | 1 |
| Faryabi, MR | 1 |
| Esmaeili, P | 1 |
| Banafshi, O | 1 |
| Mohammadi, E | 1 |
| Fathi, F | 1 |
| Mokarizadeh, A | 1 |
| E Michalska, A | 1 |
| Brilliant, KE | 1 |
| Mills, DR | 1 |
| Callanan, HM | 1 |
| Hixson, DC | 1 |
| van de Vrugt, HJ | 1 |
| Eaton, L | 1 |
| Hanlon Newell, A | 1 |
| Al-Dhalimy, M | 1 |
| Liskay, RM | 1 |
| Olson, SB | 1 |
| Grompe, M | 1 |
| Singh, G | 1 |
| Sinha, N | 1 |
| Smeenk, G | 1 |
| de Groot, AJ | 1 |
| Romeijn, RJ | 1 |
| van Buul, PP | 1 |
| Zdzienicka, MZ | 1 |
| Mullenders, LH | 1 |
| Pastink, A | 1 |
| Godthelp, BC | 1 |
| Zhong, Y | 1 |
| Shuzheng, M | 1 |
| Yingge, Z | 1 |
| Innocenzi, A | 1 |
| Latella, L | 1 |
| Messina, G | 1 |
| Simonatto, M | 1 |
| Marullo, F | 1 |
| Berghella, L | 1 |
| Poizat, C | 1 |
| Shu, CW | 1 |
| Wang, JY | 1 |
| Puri, PL | 1 |
| Cossu, G | 1 |
| Ortega-Deballon, P | 1 |
| Glehen, O | 1 |
| Levine, E | 1 |
| Piso, P | 1 |
| Sugarbaker, PH | 1 |
| Hayes-Jordan, A | 1 |
| Facy, A | 1 |
| Bakrin, N | 1 |
| Rat, P | 1 |
| Camarasa, MV | 1 |
| Galvez, VM | 1 |
| Brison, DR | 1 |
| Bachiller, D | 1 |
| Irvine, F | 1 |
| Kumarasamy, M | 1 |
| Kemp, E | 1 |
| Roberts, F | 1 |
| SUMIDA, Y | 1 |
| KOBAYASHI, K | 1 |
| NAKAYAMA, A | 1 |
| NAKAGAWA, K | 1 |
| NISHIKAWA, M | 1 |
| KOGA, K | 1 |
| MAEDA, K | 1 |
| ISHIBASHI, Y | 1 |
| Kobayashi, Y | 1 |
| Akiyama, F | 1 |
| Hasumi, K | 1 |
| Adler, ID | 1 |
| Murthy, PB | 1 |
| Prema, K | 1 |
| Fujii, T | 2 |
| Nakatsuka, T | 2 |
| Hanada, S | 1 |
| Xu, ZD | 1 |
| Yajima, A | 1 |
| Abe, Y | 1 |
| Soh, K | 1 |
| Ozawa, N | 1 |
| Takabayashi, T | 1 |
| Sato, S | 2 |
| Uehara, S | 1 |
| Suzuki, M | 1 |
| Henderson, L | 2 |
| Cole, R | 1 |
| Cole, J | 2 |
| Cole, H | 1 |
| Aghamohammadi, Z | 2 |
| Regan, T | 1 |
| Neuhäuser-Klaus, A | 1 |
| Cole, RJ | 1 |
| Okumura, S | 1 |
| Deguchi, T | 1 |
| Nakamizo, N | 1 |
| Abraham, SK | 1 |
| Woods, CG | 1 |
| Leversha, M | 1 |
| Rogers, JG | 1 |
| Der Kaloustian, VM | 1 |
| Elliott, AM | 1 |
| Eydoux, P | 1 |
| Carnegie, JA | 1 |
| Morgan, JJ | 1 |
| McDiarmid, N | 1 |
| Durnford, R | 1 |
| Rutledge, J | 1 |
| Nagao, T | 1 |
| Saitoh, Y | 1 |
| Yoshimura, S | 1 |
| Mori, Y | 1 |
| Wada, H | 1 |
| Tamaki, S | 1 |
| Minami, N | 1 |
| Shiku, H | 1 |
| Ihara, T | 1 |
| Omine, M | 1 |
| Kakisita, E | 1 |
| Blagoeva, PM | 2 |
| Balansky, RM | 2 |
| Mircheva, TJ | 2 |
| Simeonova, MI | 1 |
| Pariani, S | 1 |
| Buscaglia, M | 1 |
| Piantanida, M | 1 |
| Simoni, G | 1 |
| Sutou, S | 1 |
| Jones, WB | 1 |
| Wagner-Reiss, KM | 1 |
| Lewis, JL | 1 |
| Boike, GM | 1 |
| Deppe, G | 1 |
| Young, JD | 1 |
| Gove, NL | 1 |
| Bottoms, SF | 1 |
| Malone, JM | 1 |
| Malviya, VK | 1 |
| Sokol, RJ | 1 |
| Katayama, S | 1 |
| Matsumoto, N | 1 |
| Ando, Y | 1 |
| Nakano, S | 1 |
| Saito, K | 1 |
| Shimamoto, I | 1 |
| Ichijo, M | 1 |
| Toyama, T | 1 |
| Hinuma, Y | 1 |
| Müller, L | 2 |
| Seller, MJ | 1 |
| Perkins, KJ | 1 |
| Chen, X | 1 |
| Schmidt, B | 2 |
| Dunkelberg, H | 2 |
| Inouye, M | 1 |
| Kajiwara, Y | 1 |
| Che, XM | 1 |
| Borneff, J | 1 |
| Tam, PP | 1 |
| Snow, MH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnostic Value and Biological Significant of cd71 in Lymphoid Dis Order[NCT03720977] | 139 participants (Anticipated) | Observational | 2019-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mitomycin and Pregnancy
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Discovery of asymptomatic Krukenberg tumors diagnosed during caesarean section: therapy with hyperthermic intraperitoneal chemotherapy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherap | 2013 |
Beyond boundaries--Eph:ephrin signaling in neurogenesis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Movement; Cisplatin; Embryonic D | 2014 |
1 trial available for mitomycin and Pregnancy
53 other studies available for mitomycin and Pregnancy
| Article | Year |
|---|---|
Proteomic analysis reveals the potential positive effects of Mito-TEMPO on ram sperm motility and fertility during cryopreservation.
Topics: Animals; Antioxidants; Cryopreservation; Cryoprotective Agents; Female; Fertility; Male; Mitomycin; | 2023 |
Severe fever with thrombocytopenia syndrome virus infection during pregnancy in C57/BL6 mice causes fetal damage.
Topics: Alkylating Agents; Animals; Bunyaviridae Infections; Female; Fetus; Immunocompromised Host; Mice; Mi | 2020 |
Lower Abundance and Impaired Function of CD71+ Erythroid Cells in Inflammatory Bowel Disease Patients During Pregnancy.
Topics: Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Models, An | 2019 |
Bovine somatic cell nuclear transfer using mitomycin C-mediated chemical oocyte enucleation.
Topics: Animals; Antibiotics, Antineoplastic; Blastocyst; Cattle; Cell Nucleus; Cloning, Organism; Embryo Tr | 2019 |
Successful Delivery in a 39-Year-Old Patient with Anal Cancer after Fertility-Preserving Surgery Followed by Primary Chemoradiation and Low Anti-Mullerian Hormone Level.
Topics: Adult; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carci | 2016 |
Late Gestation Fetal Hepatocytes for Liver Repopulation in the Rat.
Topics: Animals; Cell Proliferation; Cell Transplantation; Female; Fetus; Hepatocytes; Liver; Liver Regenera | 2017 |
Altered helper T cell-mediated immune responses in male mice conceived through in vitro fertilization.
Topics: Animals; Cell Proliferation; Female; Fertilization in Vitro; GATA3 Transcription Factor; Immunoglobu | 2017 |
Isolation and propagation of mouse embryonic fibroblasts and preparation of mouse embryonic feeder layer cells.
Topics: Animals; Cell Count; Cell Culture Techniques; Cell Separation; Coculture Techniques; Cryopreservatio | 2007 |
Engraftment of syngeneic and allogeneic endothelial cells, hepatocytes and cholangiocytes into partially hepatectomized rats previously treated with mitomycin C.
Topics: Animals; Animals, Newborn; Bile Ducts; Cell Differentiation; Cell Proliferation; Dipeptidyl Peptidas | 2009 |
Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Chromosome Aberrations; DNA Mismatch Repair; Embryo, | 2009 |
Involvement of apoptosis in mediating mitomycin C-induced teratogenesis in vitro.
Topics: Animals; Apoptosis; Female; Flow Cytometry; In Vitro Techniques; Mitomycin; Pregnancy; Rats; Teratog | 2010 |
Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability.
Topics: Animals; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Damage; DNA-Binding Proteins; Embryonic | 2010 |
Using activated carbon nanoparticles to decrease the genotoxicity and teratogenicity of anticancer therapeutic agents.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Cell Line; Cell Line, Tumor | 2010 |
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Biological Evolution; Cell Cycle Proteins; Cell Dif | 2011 |
Childbearing after hyperthermic intraperitoneal chemotherapy: results from an international survey.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Pe | 2011 |
Optimized protocol for derivation of human embryonic stem cell lines.
Topics: Animals; Blastocyst Inner Cell Mass; Cell Culture Techniques; Cells, Cultured; Coculture Techniques; | 2012 |
Progression of primary acquired melanosis with atypia during pregnancy.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Conjunctival Diseases; Disease Progress | 2012 |
[On the treatment of choriocarcinoma with special reference to mitomycin C].
Topics: Choriocarcinoma; Female; Mitomycin; Mitomycins; Pregnancy | 1963 |
[PRACTICAL ASPECTS OF CHEMOTHERAPY IN HYDATIDIFORM MOLE AND CHORIOCARCINOMA].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Desoxycorticosteron | 1963 |
CANCER CHEMOTHERAPY (MITOMYCIN-C) FOLLOWED BY BONE MARROW TRANSPLANTATION.
Topics: Bone Marrow Transplantation; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Bronchogenic; Choriocarci | 1964 |
A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Thera | 2006 |
New approaches to mutagenicity studies in animals for carcinogenic and mutagenic agents. II. Clastogenic effects determined in transplacentally treated mouse embryos.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bleomycin; Chromosome Aberrations; Embryo, Mammalian; Female; | 1983 |
Further studies on sister-chromatid exchange frequency in users of hormonal contraceptives.
Topics: Contraceptive Agents, Female; Contraceptives, Oral, Combined; Crossing Over, Genetic; Ethinyl Estrad | 1983 |
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibioti | 1983 |
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; | 1983 |
Effects of radiotherapy and chemotherapy on sister chromatid exchanges in peripheral lymphocytes of the patients with gynecologic cancer.
Topics: Choriocarcinoma; Crossing Over, Genetic; Female; Genital Neoplasms, Female; Humans; Lymphocytes; Mit | 1983 |
Sister-chromatid exchange and micronucleus induction as indicators of genetic damage in maternal and foetal cells.
Topics: Animals; Bone Marrow Cells; Cell Nucleus; Crossing Over, Genetic; Cyclophosphamide; Female; Liver; M | 1984 |
An approach towards to standardization of the mammalian spot test.
Topics: Animals; Embryo, Mammalian; Female; Genotype; Methyl Methanesulfonate; Mice; Mitomycin; Mitomycins; | 1981 |
Short-term tests for transplacentally active carcinogens. Multiple-dose regimes in the transplacental micronucleus test.
Topics: Antibiotics, Antineoplastic; Carcinogens; Cell Cycle; Female; Fetus; Humans; Liver; Maternal-Fetal E | 1982 |
[Studies on the physiological disposition and pharmacokinetics of 7-N-(p-hydroxyphenyl)-mitomycin C].
Topics: Animals; Bile; Carbon Radioisotopes; Dogs; Feces; Female; Injections, Intravenous; Intestinal Absorp | 1982 |
Inhibitory effects of coffee on transplacental genotoxicity in mice.
Topics: Analysis of Variance; Animals; Antimutagenic Agents; Bone Marrow; Bone Marrow Cells; Coffee; Cycloph | 1995 |
Severe intrauterine growth retardation with increased mitomycin C sensitivity: a further chromosome breakage syndrome.
Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragility; DNA Dama | 1995 |
Severe intrauterine growth retardation with increased mitomycin C sensitivity, or Nijmegen breakage syndrome?
Topics: Chromosome Aberrations; Chromosome Disorders; Female; Fetal Growth Retardation; Humans; Male; Mitomy | 1995 |
Influence of protein supplements on the secretion of leukaemia inhibitory factor by mitomycin-pretreated Vero cells: possible application to the in vitro production of bovine blastocysts with high cryotolerance.
Topics: Animals; Blastocyst; Blood Proteins; Cattle; Chlorocebus aethiops; Coculture Techniques; Cryopreserv | 1999 |
Preimplantation teratology and the placenta.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Blastocyst; Female; Humans; Mitom | 2000 |
Possible mechanism of congenital malformations induced by exposure of mouse preimplantation embryos to mitomycin C.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Decidua; Embryonic and Fetal Development; Female; | 2000 |
Outcome of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan.
Topics: Adolescent; Adult; Aged; Aspirin; Bacterial Toxins; Child; Child, Preschool; Clinical Trials as Topi | 1999 |
Diminished genotoxicity of mitomycin C and farmorubicin included in polybutylcyanoacrylate nanoparticles.
Topics: Animals; Bone Marrow; Drug Carriers; Enbucrilate; Epirubicin; Female; Liver; Maternal-Fetal Exchange | 1992 |
Cyclophosphamide increases the frequency of sister chromatid exchange in direct preparations of human chorionic villi in the absence of supplementary enzymatic activation systems.
Topics: Biotransformation; Chorionic Villi; Cyclophosphamide; Female; Humans; Mitomycin; Mutagenicity Tests; | 1992 |
Potentiation by caffeine of the frequencies of micronuclei induced by mitomycin C and cyclophosphamide in young mice.
Topics: Alkylating Agents; Animals; Caffeine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Syner | 1991 |
Maternal effect on micronucleus induction in MS/Ae mice.
Topics: Animals; Animals, Newborn; Cell Differentiation; Colchicine; Extrachromosomal Inheritance; Female; L | 1990 |
Intracerebral choriocarcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cisplatin; | 1990 |
Chemotherapy in a pregnant rat model. 1. Mitomycin-C: pregnancy-specific kinetics and placental transfer.
Topics: Amniotic Fluid; Analysis of Variance; Animals; Female; Fetal Blood; Kinetics; Maternal-Fetal Exchang | 1989 |
Toxic effects of chemicals on mouse post-blastocyst development--a trial to establish a testing system for embryotoxicity.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antibiotics, Antineoplastic; Blastocyst; Bleomycin; Chromosome Ab | 1985 |
Prevention of HTLV-I transmission through the breast milk by a freeze-thawing process.
Topics: Antigens, Viral; Deltaretrovirus Infections; Female; Freezing; HIV Antigens; Humans; Lymphocytes; Mi | 1986 |
Stage-related induction of chromosomal aberrations and SCE in mouse embryos treated transplacentally during organogenesis with MMC and DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Embryo, Mammalian; Embryonic and | 1988 |
Micronucleus induction in mouse and rat fetuses treated transplacentally during histogenesis with mitomycin C and 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Erythroblasts; Female; Maternal-Fetal Exchange; Mice; Mic | 1988 |
Effect of mitomycin C on the neural tube defects of the curly-tail mouse.
Topics: Animals; Female; Gestational Age; Maternal-Fetal Exchange; Mice; Mice, Mutant Strains; Mitomycin; Mi | 1986 |
[The induction of sister chromatid exchange by diethylstilbestrol and mitomycin C in lymphocytes of mothers and their newborn infants].
Topics: Diethylstilbestrol; Female; Humans; Infant, Newborn; Lymphocytes; Mitomycin; Mitomycins; Pregnancy; | 1987 |
Teratogenic interactions between methylmercury and mitomycin-C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cleft Palate; Drug Synergism; Female; Methylme | 1988 |
[On the induction of sister chromatid exchange by diethylstilbestrol and mitomycin C in lymphocytes of mothers and their newborn infants].
Topics: Diethylstilbestrol; Female; Humans; Infant, Newborn; Lymphocytes; Mitomycin; Mitomycins; Pregnancy; | 1987 |
Postimplantation development of mitomycin C-treated mouse blastocysts.
Topics: Animals; Blastocyst; Cell Count; Embryonic and Fetal Development; Embryonic Development; Female; Mal | 1988 |
Restorative growth and its problems for morphogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Cell Cycle; Cell Differentiation; Cell Division; Embryo, Mamma | 1985 |