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mitomycin and Precancerous Conditions

mitomycin has been researched along with Precancerous Conditions in 9 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"Since 1995 we have used Mitomycin C additionally in the treatment of conjunctival melanoma and primary acquired melanosis."7.70[Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis]. ( Lommatzsch, PK; Werschnik, C, 1998)
" If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications."5.31[The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001)
"Since 1995 we have used Mitomycin C additionally in the treatment of conjunctival melanoma and primary acquired melanosis."3.70[Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis]. ( Lommatzsch, PK; Werschnik, C, 1998)
"To describe the epithelial changes observed in the conjunctiva secondary to the use of topical mitomycin C (MMC) for treatment of primary acquired melanosis with atypia."3.70Cytologic changes in the conjunctiva mimicking malignancy after topical mitomycin C chemotherapy. ( Cuevas, K; Folberg, R; Mathers, WD; Salomão, DR; Sutphin, JE, 1999)
" If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications."1.31[The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001)
"Baseline and mitomycin C (MMC)-induced chromosomal aberrations and sister chromatid exchanges (SCEs) in blood lymphocytes of patients with cervical precancerous and cancerous lesions and normal women were studied."1.27Mitomycin C induced chromosomal aberrations and sister chromatid exchanges (SCEs) in lymphocytes of patients with precancerous and cancerous lesions of the uterine cervix. ( Das, BC; Luthra, UK; Mitra, AB; Murty, VV; Sharma, A, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohtani, M2
Fukushima, S2
Ito, N2
Koiso, K2
Niijima, T2
Okamura, T1
Sakata, T1
Löffler, KU1
Werschnik, C1
Lommatzsch, PK1
Salomão, DR1
Mathers, WD1
Sutphin, JE1
Cuevas, K1
Folberg, R1
Schmidt, M1
Maier, M1
Schmidt, T1
Klaehsen, D1
Merté, RL1
Shields, CL1
Demirci, H1
Shields, JA1
Spanich, C1
Riley, RJ1
Workman, P1
Murty, VV1
Mitra, AB1
Sharma, A1
Das, BC1
Luthra, UK1

Reviews

1 review available for mitomycin and Precancerous Conditions

ArticleYear
DT-diaphorase and cancer chemotherapy.
    Biochemical pharmacology, 1992, Apr-15, Volume: 43, Issue:8

    Topics: Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Dihydrolipoamide Dehydrogenase; Drug Desi

1992

Other Studies

8 other studies available for mitomycin and Precancerous Conditions

ArticleYear
Effects of intravesical instillation of antitumor drugs on the induction of preneoplastic bladder lesions in rats.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Animals; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Prec

1983
Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Cancer, 1984, Oct-15, Volume: 54, Issue:8

    Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Drug Synergism; Female; H

1984
[Mitomycin as local therapeutic drug in ocular neoplasms].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:7

    Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Corneal Diseases; Eye Neoplasms; Follow-Up Stud

1997
[Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 212, Issue:6

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Ther

1998
Cytologic changes in the conjunctiva mimicking malignancy after topical mitomycin C chemotherapy.
    Ophthalmology, 1999, Volume: 106, Issue:9

    Topics: Administration, Topical; Aged; Antibiotics, Antineoplastic; Biopsy; Cell Nucleus; Conjunctiva; Conju

1999
[The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years].
    Klinische Monatsblatter fur Augenheilkunde, 2001, Volume: 218, Issue:12

    Topics: Administration, Topical; Aged; Biopsy; Cell Transformation, Neoplastic; Conjunctiva; Conjunctival Ne

2001
Dramatic regression of conjunctival and corneal acquired melanosis with topical mitomycin C.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:2

    Topics: Aged; Antibiotics, Antineoplastic; Eye Neoplasms; Follow-Up Studies; Humans; Male; Melanosis; Mitomy

2002
Mitomycin C induced chromosomal aberrations and sister chromatid exchanges (SCEs) in lymphocytes of patients with precancerous and cancerous lesions of the uterine cervix.
    Neoplasma, 1987, Volume: 34, Issue:1

    Topics: Chromosome Aberrations; Female; Humans; Lymphocytes; Mitomycin; Mitomycins; Precancerous Conditions;

1987