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mitomycin and Pleural Effusion

mitomycin has been researched along with Pleural Effusion in 14 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"A prospective randomized study to compare the effectiveness of pleurodesis by two new sclerosing agents: OK-432 and mitomycin C were conducted in 53 patients with malignant pleural effusion caused by lung cancer."9.07Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial. ( Chang, DB; Kuo, SH; Lee, LN; Luh, KT; Yang, PC; Yu, CJ, 1992)
"A prospective randomized study to compare the effectiveness of pleurodesis by two new sclerosing agents: OK-432 and mitomycin C were conducted in 53 patients with malignant pleural effusion caused by lung cancer."5.07Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial. ( Chang, DB; Kuo, SH; Lee, LN; Luh, KT; Yang, PC; Yu, CJ, 1992)
" Twenty-four patients with malignant pericardial effusion were treated by intrapericardial instillation of anti-cancer drugs, such as Carbazilquinone, Mitomycin-C or ACNU, with pericardial drainage."5.05[Local application of anti-cancer drugs for the treatment of malignant pleural and pericardial effusion]. ( Fukuoka, M; Matsui, K; Negoro, S; Ryu, S; Sakaguchi, K; Sakai, N; Takada, M; Tamai, S, 1984)
"Sixty-seven breast cancer patients with malignant pleural effusions underwent their first thoracentesis between 1980 and 1990 at 13 institutes in Kyoto and Shiga Prefectures."2.67[Intrapleural treatment of breast cancer patients with pleural effusions: an analysis of 13 institutes in Kyoto and Shiga Prefectures. Kyoto and Shiga Breast Cancer Study Group]. ( Hori, T; Kan, N; Kato, H; Kodama, H; Kudo, N; Mukaihara, S; Ogawa, H; Ohsumi, K; Takenaka, A; Yasumura, T, 1992)
"A 51-year-old woman with breast cancer metastatic to the pleura was treated with intrapleural instillation of adriamycin after thoracentesis, and systemic administration of FEMP, with complete response for more than 11 months."1.27[A case of breast cancer with pleural metastasis responding to administration of intrapleural adriamycin and systemic chemotherapy with FEMP]. ( Adachi, Y; Bada, K; Denno, R; Kohno, Y; Nishizawa, F; Ogasahara, K; Ohbayashi, M; Takahashi, J; Takeda, R; Yoshimura, T, 1987)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukuoka, M2
Takada, M2
Tamai, S1
Negoro, S1
Matsui, K1
Ryu, S1
Sakai, N1
Sakaguchi, K1
Kaneto, E1
Sasaki, H1
Tamura, I1
Kurimura, O1
Kurimura, T1
Takahashi, M2
Yoshida, K1
Ikeuchi, H1
Kano, K1
Machida, T1
Miura, Y1
Takeda, T1
Yamada, S1
Uchida, A2
Micksche, M1
Naoe, Y1
Inami, M1
Matsumoto, S1
Nishigaki, F1
Tsujimoto, S1
Kawamura, I1
Miyayasu, K1
Manda, T1
Shimomura, K1
Luh, KT1
Yang, PC1
Kuo, SH1
Chang, DB1
Yu, CJ1
Lee, LN1
Kan, N1
Kodama, H1
Hori, T1
Takenaka, A1
Yasumura, T1
Kato, H1
Ogawa, H1
Ohsumi, K1
Kudo, N1
Mukaihara, S1
Inaoka, M1
Kusajima, K1
Kawashima, T1
Iwata, M1
Morikawa, M1
Mishina, H1
Komatsu, S1
Moore, M1
Klein, E1
Takahashi, K1
Watanabe, M1
Kikuchi, J1
Kishi, H1
Saito, K1
Mouri, H1
Ikeno, N1
Endo, H1
Shima, I1
Morizuka, T1
Akiyoshi, T1
Wada, T1
Arinaga, S1
Koba, F1
Tsuji, H1
Ogasahara, K1
Takeda, R1
Nishizawa, F1
Yoshimura, T1
Denno, R1
Adachi, Y1
Takahashi, J1
Kohno, Y1
Bada, K1
Ohbayashi, M1
Yew, WW1
Chan, SL1
Kwan, SY1

Reviews

1 review available for mitomycin and Pleural Effusion

ArticleYear
[Treatment of malignant pleural effusion].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Humans; Instillation, Drug; Interleukin

1989

Trials

3 trials available for mitomycin and Pleural Effusion

ArticleYear
[Local application of anti-cancer drugs for the treatment of malignant pleural and pericardial effusion].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin;

1984
Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer. A randomized trial.
    Cancer, 1992, Feb-01, Volume: 69, Issue:3

    Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Immunity,

1992
[Intrapleural treatment of breast cancer patients with pleural effusions: an analysis of 13 institutes in Kyoto and Shiga Prefectures. Kyoto and Shiga Breast Cancer Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Doxo

1992

Other Studies

10 other studies available for mitomycin and Pleural Effusion

ArticleYear
Interferon-alpha in serum and carcinomatous pleural effusion after repeated intrapleural injections of antitumor agents.
    Biken journal, 1983, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Aged; Biological Products; Carcinoma, Small Cell; Drug Therapy, Combination; Female;

1983
[Effect of intracavitary administration of an anticancer agent with glucocorticoid on cancer patients complicated with malignant effusion].
    Nihon Gan Chiryo Gakkai shi, 1983, Jun-20, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Dexamethasone; Female; Humans; Male; Mitomycin; Mitomycins;

1983
Lysis of fresh human tumor cells by autologous peripheral blood lymphocytes and pleural effusion lymphocytes activated by OK432.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Biological Products; Cytotoxicity, Immunologic; Dactinomycin; Female; H

1983
FK317: a novel substituted dihydrobenzoxazine with potent antitumor activity which does not induce vascular leak syndrome.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:1

    Topics: Animals; Antineoplastic Agents; Capillary Leak Syndrome; Drug Screening Assays, Antitumor; Female; M

1998
[2 cases of "intrathoracic hyperthermia" as a new technic in the treatment of malignant pleural effusion].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1987, Volume: 35, Issue:3

    Topics: Bleomycin; Combined Modality Therapy; Female; Humans; Hyperthermia, Induced; Lung Neoplasms; Middle

1987
Autologous mixed lymphocyte-tumor reaction and autologous mixed lymphocyte reaction. II. Generation of specific and non-specific killer T cells capable of lysing autologous tumor.
    International journal of cancer, 1988, May-15, Volume: 41, Issue:5

    Topics: Adenocarcinoma; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Squamous Cell; Cell Separation;

1988
[Reductive effect on ascites, of neocarzinostatin in patients with ovarian cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:5

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Ascitic Fluid; Cisplatin; Female; Humans; Infusions, Intra

1988
Enhanced chemosensitivity of cells from malignant effusions under condition of exposure to high temperature.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:5

    Topics: Ascitic Fluid; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Colony-Forming Units Assay; Dox

1986
[A case of breast cancer with pleural metastasis responding to administration of intrapleural adriamycin and systemic chemotherapy with FEMP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:11

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophospha

1987
Comparison of efficacy of mitomycin-C and corynebacterium parvum in the management of malignant pleural effusion.
    Chinese medical journal, 1988, Volume: 101, Issue:10

    Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; Female; Humans; Immunotherapy; Lung Neoplasms; Male

1988