mitomycin has been researched along with Pancytopenia in 6 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because MMC is the preferred agent of choice used in CRS-HIPEC, future studies should investigate optimal MMC dosing and patient selection when splenectomy is performed to balance survival benefit with hematologic toxicities." | 5.62 | Pancytopenia after administration of hyperthermic intraperitoneal chemotherapy with mitomycin-C: local therapy and systemic toxicity. ( Chung, SY; Saif, MW; Shen, J; Wu, V, 2021) |
| "Chromosomal breakage was induced by MMC 0 ng/ml, 40 ng/ml, and 80 ng/ml." | 5.39 | [Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia]. ( Cai, XJ; Chen, XJ; Chen, YM; Guo, Y; Liu, F; Liu, Q; Liu, TF; Liu, XM; Ruan, M; Wang, SC; Yang, WY; Zhang, JY; Zhang, L; Zhu, XF; Zou, Y, 2013) |
| " Because MMC is the preferred agent of choice used in CRS-HIPEC, future studies should investigate optimal MMC dosing and patient selection when splenectomy is performed to balance survival benefit with hematologic toxicities." | 1.62 | Pancytopenia after administration of hyperthermic intraperitoneal chemotherapy with mitomycin-C: local therapy and systemic toxicity. ( Chung, SY; Saif, MW; Shen, J; Wu, V, 2021) |
| "Chromosomal breakage was induced by MMC 0 ng/ml, 40 ng/ml, and 80 ng/ml." | 1.39 | [Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia]. ( Cai, XJ; Chen, XJ; Chen, YM; Guo, Y; Liu, F; Liu, Q; Liu, TF; Liu, XM; Ruan, M; Wang, SC; Yang, WY; Zhang, JY; Zhang, L; Zhu, XF; Zou, Y, 2013) |
| "The mitomycin C-treated Fancc(-/-) mouse provides a valuable model to address long-term efficacy of such treatment." | 1.31 | Short-term granulocyte colony-stimulating factor and erythropoietin treatment enhances hematopoiesis and survival in the mitomycin C-conditioned Fancc(-/-) mouse model, while long-term treatment is ineffective. ( Buchwald, M; Carreau, M; Dick, JE; Gan, OI; Hitzler, JK; Liu, L, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, V | 1 |
| Shen, J | 1 |
| Chung, SY | 1 |
| Saif, MW | 1 |
| Zhang, L | 1 |
| Liu, Q | 1 |
| Zou, Y | 1 |
| Liu, XM | 1 |
| Zhang, JY | 1 |
| Wang, SC | 1 |
| Chen, XJ | 1 |
| Guo, Y | 1 |
| Yang, WY | 1 |
| Ruan, M | 1 |
| Liu, TF | 1 |
| Liu, F | 1 |
| Cai, XJ | 1 |
| Chen, YM | 1 |
| Zhu, XF | 1 |
| Carreau, M | 1 |
| Liu, L | 1 |
| Gan, OI | 1 |
| Hitzler, JK | 1 |
| Dick, JE | 1 |
| Buchwald, M | 1 |
| Edelman, S | 1 |
| Johnstone, PA | 1 |
| Gush, KA | 1 |
| Fu, KL | 1 |
| Grompe, M | 1 |
| Walsh, CE | 1 |
| Butler, MG | 1 |
| Hall, BD | 1 |
| Maclean, RN | 1 |
| Lozzio, CB | 1 |
6 other studies available for mitomycin and Pancytopenia
| Article | Year |
|---|---|
Pancytopenia after administration of hyperthermic intraperitoneal chemotherapy with mitomycin-C: local therapy and systemic toxicity.
Topics: Aged; Antineoplastic Agents; Female; Humans; Hyperthermic Intraperitoneal Chemotherapy; Mitomycin; P | 2021 |
[Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia].
Topics: Adolescent; Anemia, Aplastic; Case-Control Studies; Child; Child, Preschool; Chromosomal Instability | 2013 |
Short-term granulocyte colony-stimulating factor and erythropoietin treatment enhances hematopoiesis and survival in the mitomycin C-conditioned Fancc(-/-) mouse model, while long-term treatment is ineffective.
Topics: Animals; Bone Marrow; Erythrocyte Count; Erythropoietin; Fanconi Anemia; Granulocyte Colony-Stimulat | 2002 |
Combined modality therapy for HIV-infected patients with squamous cell carcinoma of the anus: outcomes and toxicities.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cis | 2006 |
Phenotypic correction of Fanconi anemia group C knockout mice.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle Proteins; DNA; DNA-Binding Prote | 2000 |
Do some patients with Seckel syndrome have hematological problems and/or chromosome breakage?
Topics: Abnormalities, Multiple; Adolescent; Child; Chromosome Aberrations; Chromosome Fragility; Chromosome | 1987 |