mitomycin has been researched along with Osteosarcoma in 15 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In all 63 patients were treated monthly with a combination of mitomycin, doxorubicin, and cisplatin, and 27 (43%) experienced objective regression of their advanced sarcomas during a 3-month trial." | 7.67 | Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas. ( Creagan, ET; Edmonson, JH; Green, SJ; Long, HJ; Richardson, RL, 1985) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "In all 63 patients were treated monthly with a combination of mitomycin, doxorubicin, and cisplatin, and 27 (43%) experienced objective regression of their advanced sarcomas during a 3-month trial." | 3.67 | Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas. ( Creagan, ET; Edmonson, JH; Green, SJ; Long, HJ; Richardson, RL, 1985) |
| "A 24-year-old patient who developed breast cancer 16 years after chemotherapy for osteosarcoma is presented." | 2.38 | Breast cancer developing after chemotherapy for osteosarcoma: a case report. ( Hishinuma, S; Ikeda, T; Inada, T; Kotake, K; Koyama, Y; Ogata, Y; Ozawa, I; Sekiguchi, C; Shimamura, K; Shimizu, H, 1991) |
| "Osteosarcoma is the most common malignant bone tumor in children and young people." | 1.38 | Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: a pilot study. ( Kallis, C; Strauss, SJ; Whelan, JS; Windsor, RE; Wood, NE, 2012) |
| "When treated with mitomycin C, p53-deficient cells, but not p53-expressing cells, showed a marked increase in ceramide levels." | 1.38 | DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells. ( Duerksen-Hughes, PJ; Filippov, V; Filippova, M; Haynes, TA; Yang, J; Zhang, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Frost, MG | 1 |
| Mazloumi Aboukheili, AM | 1 |
| Toth, R | 1 |
| Walden, H | 1 |
| Sio, TT | 1 |
| Vu, CC | 1 |
| Sohawon, S | 1 |
| Van Houtte, P | 1 |
| Thariat, J | 1 |
| Novotny, PJ | 1 |
| Miller, RC | 1 |
| Bar-Sela, G | 1 |
| Windsor, RE | 1 |
| Strauss, SJ | 1 |
| Kallis, C | 1 |
| Wood, NE | 1 |
| Whelan, JS | 1 |
| Haynes, TA | 1 |
| Filippov, V | 2 |
| Filippova, M | 2 |
| Yang, J | 1 |
| Zhang, K | 1 |
| Duerksen-Hughes, PJ | 2 |
| DAWSON, EM | 1 |
| FUJIMORI, M | 1 |
| SAKAUCHI, G | 1 |
| IZUO, M | 1 |
| ABE, C | 1 |
| MORITA, S | 1 |
| NASHIMOTO, T | 1 |
| ISHIKAWA, S | 1 |
| SADMITSU, H | 1 |
| KAWAI, T | 1 |
| Takeuchi, S | 1 |
| Akahoshi, Y | 1 |
| Kasai, C | 1 |
| Nishimoto, Y | 1 |
| Liu, C | 1 |
| Dai, G | 1 |
| Zhang, X | 1 |
| Huang, TG | 1 |
| Ip, SM | 1 |
| Yeung, WS | 1 |
| Ngan, HY | 1 |
| Zeng, J | 1 |
| Hu, Y | 1 |
| Pei, F | 1 |
| Lei, S | 1 |
| Mao, Y | 1 |
| Wei, Y | 1 |
| Ikeda, T | 1 |
| Sekiguchi, C | 1 |
| Shimamura, K | 1 |
| Ozawa, I | 1 |
| Inada, T | 1 |
| Hishinuma, S | 1 |
| Shimizu, H | 1 |
| Kotake, K | 1 |
| Ogata, Y | 1 |
| Koyama, Y | 1 |
| Edmonson, JH | 1 |
| Long, HJ | 1 |
| Richardson, RL | 1 |
| Creagan, ET | 1 |
| Green, SJ | 1 |
2 reviews available for mitomycin and Osteosarcoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Breast cancer developing after chemotherapy for osteosarcoma: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Non | 1991 |
1 trial available for mitomycin and Osteosarcoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
13 other studies available for mitomycin and Osteosarcoma
| Article | Year |
|---|---|
Characterization of FANCL variants observed in patient cancer cells.
Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Bone Neoplasms; Cell Line, Tumor; Cell Surviva | 2020 |
Extraskeletal Osteosarcoma: An International Rare Cancer Network Study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc | 2016 |
Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: a pilot study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; | 2012 |
DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.
Topics: Acid Ceramidase; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Ceramides; Colonic Neop | 2012 |
OSTEOGENIC SARCOMA IN CHILDHOOD.
Topics: Adolescent; Bone Neoplasms; Child; Humans; Infant; Methotrexate; Mitomycin; Mitomycins; Neoplasms; O | 1963 |
STUDIES ON REGIONAL PERFUSION AND INTRA-ARTERIAL INFUSION FOR CANCER CHEMOTHERAPY.
Topics: Antineoplastic Agents; Breast Neoplasms; Celiac Artery; Chemotherapy, Cancer, Regional Perfusion; Co | 1964 |
The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes.
Topics: Alternative Splicing; Antibiotics, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Colonic Neoplas | 2007 |
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; | 1984 |
[Chemosensitivity test for human osteosarcoma cells].
Topics: Antibiotics, Antineoplastic; Bone Neoplasms; Drug Screening Assays, Antitumor; Epirubicin; Humans; M | 1996 |
Mitomycin C and cisplatin enhanced the antitumor activity of p53-expressing adenovirus in cervical cancer cells.
Topics: Adenoviruses, Human; Antineoplastic Agents, Alkylating; Apoptosis; Bone Neoplasms; Carcinoma, Squamo | 2001 |
[Flow cytometry for testing chemosensitivity of malignant bone tumors].
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neop | 1999 |
Phase II study of a combination of mitomycin, doxorubicin and cisplatin in advanced sarcomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Dru | 1985 |
Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. French Bone Tumor Study Group.
Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Com | 1988 |