mitomycin has been researched along with Neoplasms, Pleural in 26 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)." | 9.12 | Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006) |
| "Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy." | 9.11 | The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004) |
| "Twelve patients with malignant pleural mesothelioma were subjected to mitomycin C (MMC) and vindesine (VDS) chemotherapy (MMC 10 mg/m2, i." | 7.68 | Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma. ( Airoma, G; Bianco, AR; Gridelli, C; Incoronato, P; Palazzolo, G; Pepe, R; Rossi, A, 1992) |
| "A new drug dosage form comprising activated carbon particles adsorbing mitomycin C (MMC-CH) is designed to slowly release its components, and has affinity for the tumor surface and lymph nodes and a tendency to stay long in the local portion." | 6.66 | Chemotherapy for carcinomatous peritonitis and pleuritis with MMC-CH, mitomycin C adsorbed on activated carbon particles. Clinical trials. ( Hagiwara, A; Itoh, T; Lee, R; Takahashi, T; Takeda, M; Ueda, T, 1987) |
| "We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)." | 5.12 | Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006) |
| "Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy." | 5.11 | The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004) |
| "Twelve patients with malignant pleural mesothelioma were subjected to mitomycin C (MMC) and vindesine (VDS) chemotherapy (MMC 10 mg/m2, i." | 3.68 | Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma. ( Airoma, G; Bianco, AR; Gridelli, C; Incoronato, P; Palazzolo, G; Pepe, R; Rossi, A, 1992) |
| "Malignant pleural mesothelioma is associated with a poor prognosis because of its resistance to treatment." | 2.69 | Results of a phase II trial of combined chemotherapy for patients with diffuse malignant mesothelioma of the pleura. ( Astoul, P; Boutin, C; Kasseyet, S, 1999) |
| "12." | 2.68 | Adjuvant immunotherapy with interleukin 2 and lymphokine-activated killer cells after noncurative resection of primary lung cancer. ( Kimura, H; Yamaguchi, Y, 1995) |
| "A new drug dosage form comprising activated carbon particles adsorbing mitomycin C (MMC-CH) is designed to slowly release its components, and has affinity for the tumor surface and lymph nodes and a tendency to stay long in the local portion." | 2.66 | Chemotherapy for carcinomatous peritonitis and pleuritis with MMC-CH, mitomycin C adsorbed on activated carbon particles. Clinical trials. ( Hagiwara, A; Itoh, T; Lee, R; Takahashi, T; Takeda, M; Ueda, T, 1987) |
| "Mean time to disease progression was 2." | 1.39 | Nonselective transarterial chemoperfusion: a palliative treatment for malignant pleural mesothelioma. ( Gurung, J; Lindemayr, S; Mbalisike, EC; Naguib, NN; Nour-Eldin, NE; Vogl, TJ; Zangos, S, 2013) |
| "Metastatic bronchioloalveolar carcinoma is an aggressive disease that is associated with a poor prognosis, similar to metastatic adenocarcinoma of the lung." | 1.28 | Metastatic bronchioloalveolar carcinoma and metastatic adenocarcinoma of the lung: comparison of clinical manifestations, chemotherapeutic responses, and prognosis. ( Eagan, RT; Feldman, ER; Schaid, DJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Lococo, F | 1 |
| Di Giorgio, A | 1 |
| Iaffaldano, A | 1 |
| Schinzari, G | 1 |
| Tabacco, D | 1 |
| Aceto, P | 1 |
| Abatini, C | 1 |
| Sollazzi, L | 1 |
| Margaritora, S | 1 |
| Zappa, L | 1 |
| Savady, R | 1 |
| Humphries, GN | 1 |
| Sugarbaker, PH | 1 |
| Senthil, M | 1 |
| Harrison, LE | 1 |
| Vogl, TJ | 1 |
| Lindemayr, S | 1 |
| Naguib, NN | 1 |
| Gurung, J | 1 |
| Nour-Eldin, NE | 1 |
| Zangos, S | 1 |
| Mbalisike, EC | 1 |
| Monneuse, O | 1 |
| Beaujard, AC | 1 |
| Guibert, B | 1 |
| Gilly, FN | 1 |
| Mulsant, P | 1 |
| Carry, PY | 1 |
| Benoit, M | 1 |
| Glehen, O | 1 |
| KOOP, CE | 1 |
| Andreopoulou, E | 1 |
| Ross, PJ | 1 |
| O'Brien, ME | 1 |
| Ford, HE | 1 |
| Priest, K | 1 |
| Eisen, T | 1 |
| Norton, A | 1 |
| Ashley, S | 1 |
| Smith, IE | 1 |
| Fennell, DA | 2 |
| Parmar, A | 1 |
| Shamash, J | 2 |
| Evans, MT | 2 |
| Sheaff, MT | 2 |
| Sylvester, R | 1 |
| Dhaliwal, K | 1 |
| Gower, N | 1 |
| Steele, J | 1 |
| Rudd, R | 1 |
| Pinto, C | 2 |
| Marino, A | 2 |
| De Pangher Manzini, V | 1 |
| Benedetti, G | 1 |
| Galetta, D | 1 |
| Mazzanti, P | 1 |
| Del Conte, G | 1 |
| dell'Amore, D | 1 |
| Piana, E | 2 |
| Giaquinta, S | 1 |
| Lopez, M | 1 |
| Martoni, A | 2 |
| Steele, JP | 1 |
| Wells, P | 1 |
| Rudd, RM | 1 |
| Stebbing, J | 1 |
| Dang, A | 1 |
| Mansfield, P | 1 |
| Ilsin, B | 1 |
| Hightower, C | 1 |
| Aravindan, N | 1 |
| Rice, D | 1 |
| Riedel, B | 1 |
| Urata, A | 1 |
| Nishimura, M | 1 |
| Ota, K | 1 |
| Rice, TW | 1 |
| Adelstein, DJ | 1 |
| Kirby, TJ | 1 |
| Saltarelli, MG | 1 |
| Murthy, SR | 1 |
| Van Kirk, MA | 1 |
| Wiedemann, HP | 1 |
| Weick, JK | 1 |
| Moriyama, A | 1 |
| Murata, I | 1 |
| Kuroda, T | 1 |
| Yoshikawa, I | 1 |
| Tabaru, A | 1 |
| Ogami, Y | 1 |
| Otsuki, M | 1 |
| Sauter, ER | 1 |
| Langer, C | 1 |
| Coia, LR | 1 |
| Goldberg, M | 1 |
| Keller, SM | 1 |
| Kimura, H | 1 |
| Yamaguchi, Y | 1 |
| Hastürk, S | 1 |
| Tastepe, I | 1 |
| Unlü, M | 1 |
| Cetin, G | 1 |
| Baris, YI | 1 |
| Kasseyet, S | 1 |
| Astoul, P | 1 |
| Boutin, C | 1 |
| Guaraldi, M | 1 |
| Melotti, B | 1 |
| Pannuti, F | 1 |
| Riviere, A | 1 |
| Gridelli, C | 1 |
| Pepe, R | 1 |
| Airoma, G | 1 |
| Incoronato, P | 1 |
| Rossi, A | 1 |
| Palazzolo, G | 1 |
| Bianco, AR | 1 |
| Feldman, ER | 1 |
| Eagan, RT | 1 |
| Schaid, DJ | 1 |
| Umsawasdi, T | 1 |
| Dhingra, HM | 1 |
| Charnsangavej, C | 1 |
| Luna, MA | 1 |
| Hagiwara, A | 2 |
| Takahashi, T | 2 |
| Lee, R | 2 |
| Ueda, T | 2 |
| Takeda, M | 2 |
| Itoh, T | 2 |
| Asakura, S | 1 |
| Matsui, T | 1 |
| Tatsumi, A | 1 |
| Fujio, A | 1 |
| Kitano, M | 1 |
| Kobashi, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double Lung Transplant REgistry Aimed for Lung-limited Malignancies (DREAM) - a Prospective Observational Registry Study for Patients Undergoing Lung Transplantation for Medically Refractory Cancers Confined to the Lungs[NCT05671887] | 125 participants (Anticipated) | Observational [Patient Registry] | 2022-11-16 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitomycin and Neoplasms, Pleural
| Article | Year |
|---|---|
[Does treatment for malignant pleural mesothelioma exist?].
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineopl | 2001 |
10 trials available for mitomycin and Neoplasms, Pleural
| Article | Year |
|---|---|
Long-term results of intrathoracic chemohyperthermia (ITCH) for the treatment of pleural malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Female; Humans; Hypertherm | 2003 |
The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; | 2004 |
Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Therapy, | 2006 |
[Randomized controlled study of OK-432 in the treatment of cancerous pleurisy].
Topics: Adult; Aged; Biological Products; Clinical Trials as Topic; Female; Humans; Lung Neoplasms; Male; Mi | 1983 |
Optimal management of malignant mesothelioma after subtotal pleurectomy: revisiting the role of intrapleural chemotherapy and postoperative radiation.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cytarabi | 1995 |
Adjuvant immunotherapy with interleukin 2 and lymphokine-activated killer cells after noncurative resection of primary lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Ce | 1995 |
Combined chemotherapy in pleurectomized malignant pleural mesothelioma patients.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; | 1996 |
Results of a phase II trial of combined chemotherapy for patients with diffuse malignant mesothelioma of the pleura.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asbestos; Cisplatin; Combined Modality | 1999 |
Combination chemotherapy with mitoxantrone, methotrexate, and mitomycin (MMM regimen) in malignant pleural mesothelioma: a phase II study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Mesothelioma; Methotrexa | 2001 |
Chemotherapy for carcinomatous peritonitis and pleuritis with MMC-CH, mitomycin C adsorbed on activated carbon particles. Clinical trials.
Topics: Charcoal; Clinical Trials as Topic; Dosage Forms; Female; Humans; Microscopy, Electron; Middle Aged; | 1987 |
15 other studies available for mitomycin and Neoplasms, Pleural
| Article | Year |
|---|---|
Hyperthermic intrathoracic chemotherapy combined to iterative cytoreductive surgery to treat a pleural carcinosis from psudomixoma peritonei. A case report.
Topics: Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Cy | 2021 |
Interstitial pneumonitis following intrapleural chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Fatal Outcom | 2009 |
Simultaneous bicavitary hyperthermic chemoperfusion in the management of pseudomyxoma peritonei with synchronous pleural extension.
Topics: Antibiotics, Antineoplastic; Female; Humans; Hyperthermia, Induced; Infusions, Parenteral; Middle Ag | 2009 |
Nonselective transarterial chemoperfusion: a palliative treatment for malignant pleural mesothelioma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Disease Progression; Femal | 2013 |
CURRENT MANAGEMENT OF NEPHROBLASTOMA AND NEUROBLASTOMA.
Topics: Antineoplastic Agents; Child; Dactinomycin; Fluorouracil; Infant; Infant, Newborn; Kidney Neoplasms; | 1964 |
Statistical validation of the EORTC prognostic model for malignant pleural mesothelioma based on three consecutive phase II trials.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemo | 2005 |
Efficacy and safety of first- or second-line irinotecan, cisplatin, and mitomycin in mesothelioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Clinical Trial | 2007 |
Intraoperative hyperthermic intrathoracic chemotherapy for pleural extension of pseudomyxoma peritonei.
Topics: Adult; Anesthesia, General; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemothera | 2007 |
Aggressive multimodality therapy for malignant pleural mesothelioma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Feasibility St | 1994 |
Pericardiac metastasis from advanced gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Fluorouracil; Heart Neoplasms; Human | 1995 |
Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; H | 1992 |
Metastatic bronchioloalveolar carcinoma and metastatic adenocarcinoma of the lung: comparison of clinical manifestations, chemotherapeutic responses, and prognosis.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Age Factors; Aged; Antineoplastic Combin | 1992 |
A case report of malignant pleural mesothelioma with long-term disease control after chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; | 1991 |
[A case of malignant pleural mesothelioma and its sensitivity tests for anti-cancer drugs].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug | 1988 |
[Chemotherapy of carcinomatous peritonitis and carcinomatous pleuritis by using activated charcoal particle adsorbing mitomycin C (MMC-CH)--studies on the clinical trials].
Topics: Animals; Carcinoma; Charcoal; Dosage Forms; Humans; Mitomycin; Mitomycins; Peritoneal Neoplasms; Ple | 1985 |