Page last updated: 2024-11-06

mitomycin and Necrosis

mitomycin has been researched along with Necrosis in 56 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Right corneal melting and scleral necrosis developed in a 77-year-old man 5 months after pterygium excision followed by topical administration of mitomycin C drops (0."7.68Corneal melting after pterygium removal followed by topical mitomycin C therapy. ( Climenhaga, DB; Ewing-Chow, DA; Gilmour, GR; Romanchuk, KG; Underhill, JH, 1992)
"Calcification of the bladder wall associated with intravesical mitomycin C for the treatment of superficial bladder cancer is a rare complication."7.67Bladder wall calcification after intravesical mitomycin C treatment of superficial bladder cancer. ( Badalament, RA; Drago, JR; Drago, PC; Lucas, J, 1989)
"Eight previously irradiated breast cancer patients with local recurrences were treated with intra-arterial infusions of 8 mg/m2 mitomycin C given at 3-week intervals."7.67Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients. ( Fodstad, O; Gundersen, S; Hager, B; Kvalheim, G, 1985)
"Mitomycin C (MMC) is a widely used agent for the adjuvant treatment of bladder tumors."5.35Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant! ( Cek, M; Fazlioglu, A; Kurtulus, FO; Parlakkilic, O; Tandogdu, Z, 2009)
"During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure."3.91Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019)
"Mitomycin C has improved the success rate of glaucoma filtering surgery in patients at high risk for surgical failure."3.70Midterm follow-up of necrotic bleb excision and advancement of the fornical conjunctiva. ( Ahn, DG; Hyung, SM, 1999)
"Presentation of one study on the incidence of fibrino-necrotic ulcers in patients undergoing endovesical chemoprophylaxis with mitomycin C."3.69[Fibrino-necrotic ulcers in endovesical chemoprophylaxis in superficial bladder carcinoma: our case histories]. ( Arnáiz Esteban, F; Espuela Orgaz, R; Fernández Rosáenz, J; Guinda Sevillano, C; Martínez Pérez, E; Nogueras Gimeno, MA; Pérez Arbej, JA, 1994)
"Intraarterial infusion therapy combining dibutyryl adenosine 3',5'-monophosphate and mitomycin C was administered to 27 patients with hepatocellular carcinoma (HCC) occluding the main portal vein."3.68Is necrosis induction therapy relevant to hepatocellular carcinoma? Prognostic evaluation viewed from necrosing feature in HCC occluding the main portal vein after treatment with DBcAMP and MMC. ( Ishii, K; Kusano, S; Matama, S; Matsuki, S; Shibata, H; Sugimoto, M, 1992)
"Right corneal melting and scleral necrosis developed in a 77-year-old man 5 months after pterygium excision followed by topical administration of mitomycin C drops (0."3.68Corneal melting after pterygium removal followed by topical mitomycin C therapy. ( Climenhaga, DB; Ewing-Chow, DA; Gilmour, GR; Romanchuk, KG; Underhill, JH, 1992)
"Calcification of the bladder wall associated with intravesical mitomycin C for the treatment of superficial bladder cancer is a rare complication."3.67Bladder wall calcification after intravesical mitomycin C treatment of superficial bladder cancer. ( Badalament, RA; Drago, JR; Drago, PC; Lucas, J, 1989)
"Eight previously irradiated breast cancer patients with local recurrences were treated with intra-arterial infusions of 8 mg/m2 mitomycin C given at 3-week intervals."3.67Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients. ( Fodstad, O; Gundersen, S; Hager, B; Kvalheim, G, 1985)
"5 mg/kg of mitomycin-C (Mit-C) resulted in 70% (n = 20) and 71% (n = 14) mortality, respectively, from 2 to 7 days after perfusion, with extensive, patchy necrosis and infarction seen on histologic examination and markedly elevated levels of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) at 6 and 24 hours after perfusion."3.66Reversal of lethal, chemotherapeutically induced acute hepatic necrosis in rats by regenerating liver cytosol. ( Falk, JA; Falk, RE; Falk, W; Makowka, L; Miyazaki, M; Venturi, D, 1983)
"Mitochondrial Bcl-2, Bax, cytochrome c and cytoplasmic caspase-3 expression, as well as toxic effect patterns, mitosis and cellular reactions due to α-tocopherol alone or combined with paclitaxel, mitomycin C and 5-flurouracil (5-FU), was studied in series obtained from human endothelial and primary Tenon's fibroblast cell cultures."1.42The evaluation of human tenon's fibroblasts and endothelial cell responses to antifibrotics alone and in combination with α-tocopherol. ( Akgün-Dar, K; Arslan, M; Bilgiç, S; Çetin, B; Engin, KN; Erdem-Kuruca, S; Gürel, E; Karadenizli, S; Yemisci, B, 2015)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."1.39Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"Mitomycin C treatment protects islets from the progression of central damage during culture."1.38Mitomycin C treatment significantly reduces central damage of islets in culture. ( Anazawa, T; Gotoh, M; Haga, J; Ise, K; Oshibe, I; Saito, T; Sato, Y; Waguri, S; Yamamoto, M, 2012)
"Patients had different sources of liver metastasis."1.38Short-term effectiveness of radiochemoembolization for selected hepatic metastases with a combination protocol. ( Akhlaghpoor, S; Amoui, M; Aziz-Ahari, A; Poorbeigi, H; Sheybani, S; Tolooee, S, 2012)
"Mitomycin C (MMC) is a widely used agent for the adjuvant treatment of bladder tumors."1.35Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant! ( Cek, M; Fazlioglu, A; Kurtulus, FO; Parlakkilic, O; Tandogdu, Z, 2009)
"Acute airway obstruction may occur in MMC-treated rabbits with tracheal wounds."1.34Benefits and risks of mitomycin use in the traumatized tracheal mucosa. ( Kim, DH; Kim, KH; Park, CI; Rha, KS; Roh, JL; Sung, MW, 2007)
" Numerical solutions of the resulting system of partial differential equations for the multicell spheroid case are compared with closed form solutions of the monolayer case, particularly with respect to the effects on the cell kill of the drug dosage and of the duration of its application."1.32Mathematical modelling of drug transport in tumour multicell spheroids and monolayer cultures. ( King, JR; Ward, JP, 2003)
"A patient with liver metastasis of pancreatic cancer received chemotherapy using mitomycin C and degradable starch microspheres."1.32Liver metastasis of pancreatic cancer managed by intra-arterial infusion chemotherapy combined with degradable starch microspheres. ( Aoki, T; Kato, F; Katsumata, K; Koyanagi, Y; Sumi, T; Suzuki, Y; Takagi, M; Tomioka, H; Yamasaki, T, 2003)
"Bile duct necrosis is a serious complication in arterial infusion chemotherapy, and the infusion chemotherapy should be suspended or the dose should be reduced for patients with abnormalities shown by hepato-biliary function tests."1.31[A case of intrahepatic bile duct necrosis following hepatic arterial infusion chemotherapy]. ( Arai, K; Iwasaki, Y; Kimura, Y; Takahashi, K; Takahashi, T; Yamaguchi, T, 2002)
"One week after treatment complete necrosis of the tumour was observed in 8 of 10 rabbits that received MMC/Lipiodol (3 mg/ml) without severe adverse effects on the surrounding caecum."1.30Targeted cancer chemotherapy for VX2 tumour implanted in the colon with lipiodol as a carrier. ( Ishimaru, Y; Kitamura, N; Konno, T; Nagamitsu, A; Oda, T; Tabaru, K, 1998)
" We conclude that there is greater risk of toxic anterior segment effects when mitomycin C is used as adjunctive therapy following filtration or pterygium surgery."1.29Ocular toxicity of mitomycin C and 5-fluorouracil in the rabbit. ( Feldman, F; Heathcote, JG; Ikeda-Douglas, JV; Morrow, GL; Stein, RM, 1994)
"A case of an amylase-producing ovarian cancer in 69-year-old woman has been investigated by light and electron microscopy, as well as by amylase isozyme analysis."1.27[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report]. ( Chiba, T; Hiura, M; Kaneko, H; Kawamurra, S; Moriwaki, S; Tanaka, M; Yokoyama, T, 1988)
"We report a case of invasive squamous cell carcinoma of the urinary bladder, which was perforated intraperitoneally after intra-arterial chemotherapy."1.27[A case of invasive squamous carcinoma of the urinary bladder perforated intraperitoneally after intra-arterial chemotherapy]. ( Sakurai, T; Sugao, H; Takatera, H; Takiuchi, H; Yokokawa, K, 1987)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199013 (23.21)18.7374
1990's12 (21.43)18.2507
2000's15 (26.79)29.6817
2010's10 (17.86)24.3611
2020's6 (10.71)2.80

Authors

AuthorsStudies
Lindner, AK1
Tulchiner, G1
Klinglmair, G1
Trafoier, T1
Nguyen, VA1
Kafka-Ritsch, R1
Perathoner, A1
Pichler, R1
Baron, E2
Gushchin, V2
Spiliotis, J2
King, MC1
Sardi, A2
Baron, C1
Buchholz, M1
Majchrzak-Stiller, B1
Peters, I1
Fein, D1
Müller, T1
Uhl, W1
Höhn, P1
Strotmann, J1
Braumann, C1
Lo, WJ1
Kuang, TM1
Chen, SJ1
Hwang, DK1
Azar, NS1
Ruiz-Lozano, RE1
Quiroga-Garza, ME1
Soifer, M1
Mousa, HM1
Komai, S1
Leverenz, DL1
Perez, VL1
Velez-Mejia, C1
Sittig, M1
Nikiforchin, A1
Lopez-Ramirez, F1
Razmi, M1
Rabbani-Chadegani, A1
Hashemi-Niasari, F1
Ghadam, P1
Giuliani, A1
Romanzi, F1
Di Sibio, A1
Calvisi, G1
Lombardi, L1
Marchese, M1
Di Staso, M1
Schietroma, M1
Carlei, F1
Romano, L1
Agito, MD1
Gacad, R1
Doyen, J1
Benezery, K1
Follana, P1
Ortholan, C1
Gérard, JP1
Hannoun-Levi, JM1
Gal, J1
Francois, E1
Engin, KN1
Erdem-Kuruca, S1
Akgün-Dar, K1
Çetin, B1
Karadenizli, S1
Gürel, E1
Yemisci, B1
Bilgiç, S1
Arslan, M1
Parada-Vásquez, RH1
Benítez-Castrillón, PC1
de León-Ortega, JE1
León-Roldán, CR1
Fazlioglu, A1
Tandogdu, Z1
Kurtulus, FO1
Parlakkilic, O1
Cek, M1
Branchereau, J1
Luyckx, F1
Hitier, M1
Karam, G1
Bouchot, O1
Rigaud, J1
Saito, T2
Sato, Y1
Ise, K1
Anazawa, T1
Oshibe, I1
Haga, J1
Yamamoto, M1
Waguri, S1
Gotoh, M1
Pinheiro-Chaves, A1
Akhlaghpoor, S1
Aziz-Ahari, A1
Amoui, M1
Tolooee, S1
Poorbeigi, H1
Sheybani, S1
Ward, JP1
King, JR1
Kimura, Y1
Arai, K1
Iwasaki, Y1
Takahashi, K1
Yamaguchi, T1
Takahashi, T1
Katsumata, K1
Tomioka, H1
Sumi, T1
Yamasaki, T1
Takagi, M1
Kato, F1
Suzuki, Y1
Aoki, T1
Koyanagi, Y1
Schrijvers, DL1
Tanaka, T1
Umesaki, N1
Roh, JL1
Kim, DH1
Rha, KS1
Sung, MW1
Kim, KH1
Park, CI1
Miyazaki, M2
Makowka, L1
Falk, RE1
Falk, JA1
Falk, W1
Venturi, D1
Higuchi, T1
Kikuchi, M1
Okazaki, M1
Lygidakis, NJ1
Kosmidis, P1
Ziras, N1
Parissis, J1
Kyparidou, E1
Morrow, GL1
Stein, RM1
Heathcote, JG1
Ikeda-Douglas, JV1
Feldman, F1
Guinda Sevillano, C1
Arnáiz Esteban, F1
Fernández Rosáenz, J1
Pérez Arbej, JA1
Martínez Pérez, E1
Nogueras Gimeno, MA1
Espuela Orgaz, R1
Nagamitsu, A1
Konno, T1
Oda, T1
Tabaru, K1
Ishimaru, Y1
Kitamura, N1
Guillouf, C1
Wang, TS1
Liu, J1
Walsh, CE1
Poirier, GG1
Moustacchi, E1
Rosselli, F1
Hyung, SM1
Ahn, DG1
Murakami, Y1
Shibata, S1
Koso, S1
Nagae, S1
Furue, M1
Brady, JD1
Assimos, DG1
Jordan, GH1
Neulander, EZ1
Lismer, L1
Kaneti, J1
Beckerbauer, L1
Tepe, JJ1
Cullison, J1
Reeves, R1
Williams, RM1
Martin, DS1
Bertino, JR1
Koutcher, JA1
Erard, AC1
Monnier, P1
Spiliopoulos, A1
Nicod, L1
Deng, YC1
Zhen, YS1
Zheng, S1
Xue, YC1
Szabó, IL1
Pai, R1
Jones, MK1
Ehring, GR1
Kawanaka, H1
Tarnawski, AS1
Ishii, K1
Sugimoto, M1
Matsuki, S1
Matama, S1
Shibata, H1
Kusano, S1
Ewing-Chow, DA1
Romanchuk, KG1
Gilmour, GR1
Underhill, JH1
Climenhaga, DB1
Niimi, T1
Kajita, M1
Saito, H1
Fumagalli, U1
Trabucchi, E1
Soligo, M1
Rosati, R1
Rebuffat, C1
Tonelli, C1
Montorsi, M1
Westland, K1
Pollard, JD1
Sumner, AJ1
Aizawa, H1
Tagami, H1
Kawamurra, S1
Hiura, M1
Kaneko, H1
Yokoyama, T1
Tanaka, M1
Chiba, T1
Moriwaki, S1
Okayasu, I1
Hatakeyama, S1
Yoshida, T1
Yoshimatsu, S1
Tsuruta, K1
Miyamoto, H1
Kimula, Y1
Sato, T1
Drago, PC1
Badalament, RA1
Lucas, J1
Drago, JR1
Rockwell, S1
Verweij, J1
Stoter, G1
Averbuch, SD1
Boldt, M1
Gaudiano, G1
Stern, JB1
Koch, TH1
Bachur, NR1
Takiuchi, H1
Sugao, H1
Yokokawa, K1
Takatera, H1
Sakurai, T1
Fujimoto, S1
Endoh, F1
Takahashi, O1
Shrestha, RD1
Okui, K1
Morimoto, Y1
Terao, K1
Khanna, AK1
Khanna, A1
Asthana, AK1
Misra, MK1
Kvalheim, G1
Gundersen, S1
Hager, B1
Fodstad, O1

Reviews

3 reviews available for mitomycin and Necrosis

ArticleYear
Extravasation: a dreaded complication of chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14 Suppl 3

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Dimethyl Sulfoxide; Doxorubicin; Extravasa

2003
ATP depletion + pyrimidine depletion can markedly enhance cancer therapy: fresh insight for a new approach.
    Cancer research, 2000, Dec-15, Volume: 60, Issue:24

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Ci

2000
Severe side effects of the cytotoxic drug mitomycin-C.
    The Netherlands journal of medicine, 1987, Volume: 30, Issue:1-2

    Topics: Animals; Heart Failure; Hepatic Veno-Occlusive Disease; Humans; Kidney Diseases; Mitomycin; Mitomyci

1987

Trials

1 trial available for mitomycin and Necrosis

ArticleYear
Combined transarterial targeting locoregional immunotherapy-chemotherapy for patients with unresectable hepatocellular carcinoma: a new alternative for an old problem.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1995, Volume: 15, Issue:5

    Topics: Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, He

1995

Other Studies

52 other studies available for mitomycin and Necrosis

ArticleYear
Rare, but severe: Delayed genitoscrotal necrosis after HIPEC with Mitomycin-C.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2022, Volume: 48, Issue:3

    Topics: Cytoreduction Surgical Procedures; Genitalia; Humans; Hyperthermic Intraperitoneal Chemotherapy; Mit

2022
Reply to: Letter to editor - "Rare, but severe: Delayed Genitoscrotal necrosis after HIPEC with Mitomycin-C″.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2022, Volume: 48, Issue:3

    Topics: Cytoreduction Surgical Procedures; Genitalia; Humans; Hyperthermic Intraperitoneal Chemotherapy; Mit

2022
Substance GP-2250 as a New Therapeutic Agent for Malignant Peritoneal Mesothelioma-A 3-D In Vitro Study.
    International journal of molecular sciences, 2022, Jun-30, Volume: 23, Issue:13

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin;

2022
Acute Necrotizing Retinopathy After Xen Gel Stent Implantation.
    Journal of glaucoma, 2023, 05-01, Volume: 32, Issue:5

    Topics: Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged;

2023
Delayed presentation of surgically induced scleral necrosis after I-BRITE procedure treated with immunosuppressive therapy.
    Digital journal of ophthalmology : DJO, 2023, Volume: 29, Issue:3

    Topics: Adult; Conjunctiva; Female; Humans; Immunosuppression Therapy; Mitomycin; Necrosis; Sclera

2023
Delayed genital necrosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy with Mitomycin-C.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:9

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Combined Modality Therapy; Cytoreduction Surgica

2021
Lithium chloride attenuates mitomycin C induced necrotic cell death in MDA-MB-231 breast cancer cells via HMGB1 and Bax signaling.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2018, Volume: 48

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Scre

2018
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
    Annali italiani di chirurgia, 2019, Jun-26, Volume: 8

    Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si

2019
Extensive hepatic necrosis after transarterial chemoembolization.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014, Volume: 33, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemoembolization, Therapeutic; Cis

2014
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2013
The evaluation of human tenon's fibroblasts and endothelial cell responses to antifibrotics alone and in combination with α-tocopherol.
    Current eye research, 2015, Volume: 40, Issue:1

    Topics: Alkylating Agents; alpha-Tocopherol; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3;

2015
Scleral patch graft in the management of necrotising scleritis with inflammation. A case report.
    Archivos de la Sociedad Espanola de Oftalmologia, 2016, Volume: 91, Issue:7

    Topics: Allografts; Amnion; Female; Humans; Middle Aged; Mitomycin; Necrosis; Postoperative Complications; P

2016
Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant!
    Urologia internationalis, 2009, Volume: 83, Issue:3

    Topics: Administration, Intravesical; Aged; Anti-Bacterial Agents; Cystectomy; Cystitis; Humans; Male; Mitom

2009
[Bladder necrosis after an immediate post-operative mitomycin C instillation].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2011, Volume: 21, Issue:2

    Topics: Administration, Intravesical; Aged; Antibiotics, Antineoplastic; Humans; Male; Mitomycin; Necrosis;

2011
Mitomycin C treatment significantly reduces central damage of islets in culture.
    Pancreas, 2012, Volume: 41, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cyclin-Dependent Kinase Inhibitor p21; Cytoprotect

2012
Scleral melting secondary to surgical excision of a pterygium augmented with mitomycine C application.
    Bulletin de la Societe belge d'ophtalmologie, 2012, Issue:319

    Topics: Aged; Female; Humans; Mitomycin; Necrosis; Postoperative Complications; Pterygium; Sclera; Scleral D

2012
Short-term effectiveness of radiochemoembolization for selected hepatic metastases with a combination protocol.
    World journal of gastroenterology, 2012, Oct-07, Volume: 18, Issue:37

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemoemboliz

2012
Mathematical modelling of drug transport in tumour multicell spheroids and monolayer cultures.
    Mathematical biosciences, 2003, Volume: 181, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Computer Simulation; Dose-Response Relations

2003
[A case of intrahepatic bile duct necrosis following hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Alkaline Phosphatase; Antibiotics, Antineoplastic; Bile Ducts, Intrahepatic; gamma-Glutamyltransfera

2002
Liver metastasis of pancreatic cancer managed by intra-arterial infusion chemotherapy combined with degradable starch microspheres.
    International journal of clinical oncology, 2003, Volume: 8, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Diseases; Carcinoma, Hepatocellular; Chemo

2003
Effects of mitomycin C on radiation-induced cell death in human cervical squamous cell carcinomas.
    European journal of gynaecological oncology, 2005, Volume: 26, Issue:4

    Topics: Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Combined Modali

2005
Benefits and risks of mitomycin use in the traumatized tracheal mucosa.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 136, Issue:3

    Topics: Airway Obstruction; Animals; Antibiotics, Antineoplastic; Cause of Death; Cicatrix; Disease Models,

2007
Reversal of lethal, chemotherapeutically induced acute hepatic necrosis in rats by regenerating liver cytosol.
    Surgery, 1983, Volume: 94, Issue:2

    Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Cytosol; Fluorouracil; Hyperthermia,

1983
Hepatocellular carcinoma after transcatheter hepatic arterial embolization. A histopathologic study of 84 resected cases.
    Cancer, 1994, May-01, Volume: 73, Issue:9

    Topics: Adolescent; Adult; Aged; Antigens, Neoplasm; Carcinoma, Hepatocellular; Catheterization, Peripheral;

1994
Ocular toxicity of mitomycin C and 5-fluorouracil in the rabbit.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1994, Volume: 29, Issue:6

    Topics: Animals; Corneal Edema; Corneal Neovascularization; Eye; Eyelids; Fluorouracil; Mitomycin; Necrosis;

1994
[Fibrino-necrotic ulcers in endovesical chemoprophylaxis in superficial bladder carcinoma: our case histories].
    Actas urologicas espanolas, 1994, Volume: 18, Issue:5

    Topics: Administration, Intravesical; Aged; Carcinoma; Combined Modality Therapy; Female; Fibrosis; Follow-U

1994
Targeted cancer chemotherapy for VX2 tumour implanted in the colon with lipiodol as a carrier.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Carriers; Female; Infusions, Intra-Art

1998
Fanconi anemia C protein acts at a switch between apoptosis and necrosis in mitomycin C-induced cell death.
    Experimental cell research, 1999, Feb-01, Volume: 246, Issue:2

    Topics: Apoptosis; Caspase 3; Caspases; Cell Cycle Proteins; DNA Fragmentation; DNA-Binding Proteins; Enzyme

1999
Midterm follow-up of necrotic bleb excision and advancement of the fornical conjunctiva.
    Korean journal of ophthalmology : KJO, 1999, Volume: 13, Issue:2

    Topics: Adult; Alkylating Agents; Conjunctiva; Female; Follow-Up Studies; Glaucoma; Humans; Intraoperative P

1999
Delayed tissue necrosis associated with mitomycin-C administration.
    The Journal of dermatology, 2000, Volume: 27, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Biopsy, Needle; Carcinoma, Squamous Cell; Extravasation of Diagno

2000
Urethral slough: a rare and previously unreported complication of intravesical mitomycin.
    The Journal of urology, 2000, Volume: 164, Issue:4

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; Humans; Male; Middle Aged; Mitomycin; Nec

2000
Necrosis of the glans penis: a rare complication of intravesical therapy with mitomycin c.
    The Journal of urology, 2000, Volume: 164, Issue:4

    Topics: Administration, Intravesical; Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Human

2000
FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo.
    Chemistry & biology, 2000, Volume: 7, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Cell Division; Cross-Linking Reagents; DNA; DNA-Bin

2000
Mitomycin C for control of recurrent bronchial stenosis: a case report.
    Chest, 2001, Volume: 120, Issue:6

    Topics: Administration, Topical; Adult; Airway Obstruction; Bronchi; Bronchial Diseases; Cystic Fibrosis; Di

2001
Activity of boanmycin against colorectal cancer.
    World journal of gastroenterology, 2001, Volume: 7, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bleomycin; Colorectal Neoplas

2001
Indomethacin delays gastric restitution: association with the inhibition of focal adhesion kinase and tensin phosphorylation and reduced actin stress fibers.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:6

    Topics: Actins; Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cell Line; Cell Movement; Cyclooxygenas

2002
Is necrosis induction therapy relevant to hepatocellular carcinoma? Prognostic evaluation viewed from necrosing feature in HCC occluding the main portal vein after treatment with DBcAMP and MMC.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bucladesine; Carcinoma, Hepatocellular;

1992
Corneal melting after pterygium removal followed by topical mitomycin C therapy.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1992, Volume: 27, Issue:4

    Topics: Administration, Topical; Aged; Cornea; Humans; Keratoplasty, Penetrating; Male; Mitomycin; Necrosis;

1992
Necrotizing bronchial aspergillosis in a patient receiving neoadjuvant chemotherapy for non-small cell lung carcinoma.
    Chest, 1991, Volume: 100, Issue:1

    Topics: Aged; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus

1991
Effects of intraperitoneal chemotherapy on anastomotic healing in the rat.
    The Journal of surgical research, 1991, Volume: 50, Issue:1

    Topics: Anastomosis, Surgical; Animals; Hydroxyproline; Injections, Intraperitoneal; Injections, Intravenous

1991
Mitomycin C induces a delayed and prolonged demyelination and conduction block due to Schwann cell destruction.
    Clinical and experimental neurology, 1990, Volume: 27

    Topics: Action Potentials; Animals; Demyelinating Diseases; Male; Microscopy, Electron; Mitomycin; Myelin Sh

1990
Delayed tissue necrosis due to mitomycin C.
    Acta dermato-venereologica, 1987, Volume: 67, Issue:4

    Topics: Humans; Male; Middle Aged; Mitomycin; Mitomycins; Necrosis; Skin Ulcer

1987
[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:4

    Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Female; Humans; Middle

1988
Selective and persistent deposition and gradual drainage of iodized oil, Lipiodol in the hepatocellular carcinoma after injection into the feeding hepatic artery.
    American journal of clinical pathology, 1988, Volume: 90, Issue:5

    Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Electron Probe Microanalysis; Embolization, Therapeut

1988
[Microvascular injury in hyperthermia by injecting warm water using noradrenaline into tumor feeding artery-induced tumor necrosis of Walker-256].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Animals; Arteries; Carcinoma 256, Walker; Combined Modality Therapy; Endothelium, Vascular; Hyperthe

1989
Bladder wall calcification after intravesical mitomycin C treatment of superficial bladder cancer.
    The Journal of urology, 1989, Volume: 142, Issue:4

    Topics: Administration, Intravesical; Calcinosis; Carcinoma, Transitional Cell; Humans; Male; Middle Aged; M

1989
Toxicity of intra-arterial mitomycin C to previously-irradiated tissues.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1986, Volume: 6, Issue:1

    Topics: Humans; Infusions, Intra-Arterial; Mitomycin; Mitomycins; Necrosis; Radiotherapy; Skin

1986
Experimental chemotherapy-induced skin necrosis in swine. Mechanistic studies of anthracycline antibiotic toxicity and protection with a radical dimer compound.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Drug Interactions; Female; Free Radicals; Mitomyc

1988
[A case of invasive squamous carcinoma of the urinary bladder perforated intraperitoneally after intra-arterial chemotherapy].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; H

1987
Effects of intra-arterially infused biodegradable microspheres containing mitomycin C.
    Cancer, 1985, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Arterioles; Biodegradation, Environmental; Hepatic Artery; Inf

1985
Mitomycin C extravasation ulcers.
    Journal of surgical oncology, 1985, Volume: 28, Issue:2

    Topics: Extravasation of Diagnostic and Therapeutic Materials; Humans; Infusions, Parenteral; Mitomycin; Mit

1985
Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 4, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Female; Humans; Infusions, Intra-Arteria

1985