Page last updated: 2024-11-06

mitomycin and Nasopharyngeal Carcinoma

mitomycin has been researched along with Nasopharyngeal Carcinoma in 4 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to investigate the inhibitory effects of mitomycin C (MMC) combined with a novel antibody fragment (Fab) targeting latent membrane protein 1 (LMP1) on nasopharyngeal carcinoma (NPC) xenograft nude mice."7.78A novel LMP1 antibody synergizes with mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor. ( Cao, Q; Chen, RJ; Feng, ZQ; Mao, Y; Wen, J; Zhang, DW; Zhu, J, 2012)
" The aim of this study was to investigate the inhibitory effects of mitomycin C (MMC) combined with a novel antibody fragment (Fab) targeting latent membrane protein 1 (LMP1) on nasopharyngeal carcinoma (NPC) xenograft nude mice."3.78A novel LMP1 antibody synergizes with mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor. ( Cao, Q; Chen, RJ; Feng, ZQ; Mao, Y; Wen, J; Zhang, DW; Zhu, J, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, X1
Zhang, Q1
Tian, L1
Guo, Z1
Liu, C1
Chen, J1
Ebrahim, W1
Liu, Z1
Proksch, P1
Zou, K1
Huang, J1
Li, Q1
Zheng, Y1
Shen, J1
Li, B1
Zou, R1
Wang, J1
Yuan, Y1
Chen, R1
Zhang, D1
Mao, Y2
Zhu, J2
Ming, H1
Wen, J2
Ma, J1
Cao, Q2
Lin, H1
Tang, Q1
Liang, J1
Feng, Z1
Zhang, DW1
Chen, RJ1
Feng, ZQ1

Reviews

1 review available for mitomycin and Nasopharyngeal Carcinoma

ArticleYear
Partial hepatectomy for liver metastases from nasopharyngeal carcinoma: a comparative study and review of the literature.
    BMC cancer, 2014, Nov-07, Volume: 14

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoembolization, Th

2014

Other Studies

3 other studies available for mitomycin and Nasopharyngeal Carcinoma

ArticleYear
Germacrane-Type Sesquiterpenoids with Antiproliferative Activities from Eupatorium chinense.
    Journal of natural products, 2018, 01-26, Volume: 81, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Ce

2018
A human Fab-based immunoconjugate specific for the LMP1 extracellular domain inhibits nasopharyngeal carcinoma growth in vitro and in vivo.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Carcinoma; Cell Line, Tumor; Cell Prolifer

2012
A novel LMP1 antibody synergizes with mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor.
    International journal of molecular sciences, 2012, Volume: 13, Issue:2

    Topics: Animals; Antibodies; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Dr

2012