Page last updated: 2024-11-06

mitomycin and Myotonic Dystrophy

mitomycin has been researched along with Myotonic Dystrophy in 3 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.

Research Excerpts

ExcerptRelevanceReference
"The spontaneous and mitomycin C (MMC) induced sister chromatid exchange (SCE) frequencies were examined in five adults with myotonic dystrophy (MD)."7.66Apparent enhanced response to the induction of sister chromatid exchange by mitomycin C in myotonic dystrophy. ( Emery, AE; Evans, HJ, 1982)
"The spontaneous and mitomycin C (MMC) induced sister chromatid exchange (SCE) frequencies were examined in five adults with myotonic dystrophy (MD)."3.66Apparent enhanced response to the induction of sister chromatid exchange by mitomycin C in myotonic dystrophy. ( Emery, AE; Evans, HJ, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piñeiro, E1
Fernàndez-López, L1
Gamez, J1
Marcos, R1
Surrallés, J1
Velázquez, A1
Hashem, VI1
Pytlos, MJ1
Klysik, EA1
Tsuji, K1
Khajavi, M1
Khajav, M1
Ashizawa, T1
Sinden, RR1
Emery, AE1
Evans, HJ1

Other Studies

3 other studies available for mitomycin and Myotonic Dystrophy

ArticleYear
Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1.
    Nucleic acids research, 2003, Dec-01, Volume: 31, Issue:23

    Topics: Alleles; Cells, Cultured; Chromosome Fragility; Humans; Mitomycin; Mutagenesis; Myotonic Dystrophy;

2003
Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients.
    Nucleic acids research, 2004, Volume: 32, Issue:21

    Topics: Alleles; Antineoplastic Agents, Alkylating; Cell Line; Doxorubicin; Ethyl Methanesulfonate; Humans;

2004
Apparent enhanced response to the induction of sister chromatid exchange by mitomycin C in myotonic dystrophy.
    Journal of medical genetics, 1982, Volume: 19, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Crossing Over, Genetic; Dose-Response Relationship, Drug; Female

1982