Page last updated: 2024-11-06

mitomycin and Myopia

mitomycin has been researched along with Myopia in 106 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the safety and efficacy of 5 seconds of mitomycin-C (MMC) application during photorefractive keratectomy (PRK) for low myopia."9.17Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia. ( Almasi-Nasrabadi, M; Eslani, M; Ramezanzadeh, M; Rezazadeh, P; Shojaei, A; Soleyman-Jahi, S, 2013)
"To compare photorefractive keratectomy (PRK) with prophylactic use of mitomycin C (MMC) and LASIK in custom surgeries for myopic astigmatism."9.13Photorefractive keratectomy with mitomycin C versus LASIK in custom surgeries for myopia: a bilateral prospective randomized clinical trial. ( Campos, M; Wallau, AD, 2008)
"The results show the efficacy of mitomycin-C in preventing corneal haze after treatment of high myopia with PRK."9.11Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study. ( Fotouhi, A; Hashemi, H; Kheiltash, A; Taheri, SM, 2004)
"This review details the current understanding of the mechanism of action and corneal effects of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive keratectomy (PRK), and includes discussion of available information on dosage and exposure time recommended for MMC during PRK."9.05Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK. ( Carlos de Oliveira, R; Wilson, SE, 2020)
"02% mitomycin C (MMC) used for up to 2 minutes after surface ablation for correction of myopia."8.87Meta-analysis of clinical outcomes comparing surface ablation for correction of myopia with and without 0.02% mitomycin C. ( Chen, SH; Feng, YF; Stojanovic, A; Wang, QM, 2011)
"Postoperative complications related to overfiltration were less frequent after canaloplasty with mitomycin C."8.12Is canaloplasty with mitomycin c a safe procedure in myopic glaucoma? ( Dietlein, TS; Dooling, V; Lappas, A, 2022)
"ASLA-SCHWIND TransPRK without mitomycin-C appears to be safe as well as effective and accurate for high myopia."8.02Efficacy and safety of single-step transepithelial photorefractive keratectomy with the all-surface laser ablation SCHWIND platform without mitomycin-C for high myopia: A retrospective study of 69 eyes. ( Bloch, F; El Nar, A; Giral, JB; Goetz, C; Lhuillier, L; Perone, JM; Sot, M; Vermion, JC; Zevering, Y, 2021)
"To compare efficacy and safety of single-step transepithelial photorefractive keratectomy (PRK) with or without mitomycin C (MMC) in patients with mild to moderate myopia."7.88Comparison of Single-Step Transepithelial Photorefractive Keratectomy With or Without Mitomycin C in Mild to Moderate Myopia. ( Adib-Moghaddam, S; Grentzelos, MA; Kymionis, GD; Soleyman-Jahi, S; Tefagh, G; Tofighi, S, 2018)
"The purpose of this study was to evaluate the predictability and stability of laser-assisted subepithelial keratectomy (LASEK) with mitomycin C (MMC) in correction of high myopia (≤-6."7.85Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia. ( Chen, IN; Fan, MCY; Iu, LPL; Lai, JSM, 2017)
"To evaluate the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia."7.85Long-term Follow-up of LASEK With Mitomycin C Performed to Correct Myopia in Thin Corneas. ( Drake Rodriguez-Casanova, P; Garcia-Gonzalez, M; Rodero, A; Rodriguez-Perez, I; Teus, MA, 2017)
"Photorefractive keratectomy (PRK) is a safe and effective surgical keratorefractive technique which is done with the application of mitomycin-C (MMC) in cases of high myopia to prevent the formation of corneal haze This study was conducted to evaluate 3-year visual acuity and quality outcomes of PRK-MMC in high myopia."7.85Photorefractive Keratectomy With Mitomycin-C for High Myopia: Three Year Follow-Up Results. ( Asgari, S; Hashemi, H; Pir, P; Salimi, Y, 2017)
"To examine the refractive and visual outcome of laser-assisted subepithelial keratomileusis (LASEK) with mitomycin C(MMC) in eyes with myopic astigmatism ≥2."7.80Laser-assisted subepithelial keratomileusis with mitomycin C for myopic astigmatism ≥2.00 diopters using a Zeiss MEL 80 Excimer. ( Ardjomand, N; El-Shabrawi, Y; Frings, A; Vidic, B, 2014)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) for the treatment of severe pediatric anisometropia and amblyopia resistant to more conservative treatment modalities."7.78Pediatric PRK (PhotoRefractive Keratectomy) with Mitomycin C (MCC) for Persistent Anisometropic Amblyopia. A Case Report. ( Arnold, RW; Crawford, CM; Frazier, TC; Mazzoli, RA; Raymond, WR; Torres, MF, 2012)
"To report the use of photorefractive keratectomy (PRK) with mitomycin-C (MMC) to treat concomitant myopia and visually significant infiltrates associated with epidemic keratoconjunctivitis (EKC)."7.78Photorefractive keratectomy with mitomycin-C for the combined treatment of myopia and subepithelial infiltrates after epidemic keratoconjunctivitis. ( Alevi, D; Barsam, A; Donnenfeld, ED; Kruh, J; Perry, HD; Prince, J, 2012)
"To report topography-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) after penetrating keratoplasty for keratoconus."7.75Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report. ( Alves, MR; Barreto, J; Bechara, SJ; Nakano, M; Netto, MV; Reis, A, 2009)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with intraoperative mitomycin C (MMC) after deep anterior lamellar keratoplasty (DALK) for keratoconus."7.74Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus. ( Leccisotti, A, 2008)
"To evaluate the efficacy and safety of prophylactic mitomycin C (MMC) during photorefractive keratectomy (PRK) over LASIK flaps for the treatment of residual refractive errors following LASIK."7.74Photorefractive keratectomy with 0.02% mitomycin C for treatment of residual refractive errors after LASIK. ( Drake, A; Herzig, S; Srinivasan, S, 2008)
"We report a case of controlled buccal pemphigus vulgaris with compound moderate myopia with astigmatism that was treated with photorefractive keratectomy with mitomycin-C (PRK+MMC) in both eyes."7.74Photorefractive keratectomy with mitomycin-C for the treatment of compound moderate myopia with astigmatism in buccal pemphigus vulgaris. ( Kheiltash, A; Taheri, SM, 2007)
"To compare the postoperative pain, visual recovery, and outcomes of flap-on and flap-off epithelial laser in situ keratomileusis (epi-LASIK) with mitomycin-C (MMC)."6.76Wavefront-guided epithelial laser in situ keratomileusis with mitomycin-C for myopia and myopic astigmatism: flap-on versus flap-off technique. ( Ang, RE; Hernandez, JA; Reyes, KB; Tchah, H, 2011)
" However, for moderate myopia and shallow depth, low dosing appears to be equally effective."5.35Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia. ( Krueger, RR; Thornton, I; Xu, M, 2008)
"To evaluate ocular straylight before and after photorefractive keratectomy (PRK) for low myopia with and without topical mitomycin (MMC) treatment."5.22Intraocular straylight before and after low myopic photorefractive keratectomy with and without mitomycin C. ( Bechara, SJ; Crestana, FP; Netto, MV; Parede, TR; Torricelli, AA, 2016)
"To compare visual outcomes following photorefractive keratectomy (PRK), PRK with mitomycin C (MMC-PRK), and LASEK in moderate and high myopia in military personnel."5.19The U.S. Army Surface Ablation Study: comparison of PRK, MMC-PRK, and LASEK in moderate to high myopia. ( Bower, KS; Edwards, JD; Ryan, DS; Sia, RK; Stutzman, RD, 2014)
"To assess the effect of mitomycin-C (MMC) on the tear film, corneal biomechanics, and surface irregularity in surface ablation (photorefractive keratectomy [PRK]) for low to moderate myopia."5.19Effects of mitomycin-C on tear film, corneal biomechanics, and surface irregularity in mild to moderate myopic surface ablation: preliminary results. ( Abdolahinia, T; Ashrafi, E; Jabbarvand, M; Mir-AbouTalebi, M; Mohammadi, SF; Norouzi, N, 2014)
"To assess the effects of adjuvant mitomycin C (MMC) on tear function tests after photorefractive keratectomy (PRK) for myopia."5.17The effects of mitomycin C on tear function after photorefractive keratectomy: a contralateral comparative study. ( Farahi, A; Hashemi, H; Mehravaran, S, 2013)
"To evaluate the safety and efficacy of 5 seconds of mitomycin-C (MMC) application during photorefractive keratectomy (PRK) for low myopia."5.17Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia. ( Almasi-Nasrabadi, M; Eslani, M; Ramezanzadeh, M; Rezazadeh, P; Shojaei, A; Soleyman-Jahi, S, 2013)
"To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction of myopia."5.14One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK. ( Campos, M; Wallau, AD, 2009)
"To compare photorefractive keratectomy (PRK) with prophylactic use of mitomycin C (MMC) and LASIK in custom surgeries for myopic astigmatism."5.13Photorefractive keratectomy with mitomycin C versus LASIK in custom surgeries for myopia: a bilateral prospective randomized clinical trial. ( Campos, M; Wallau, AD, 2008)
"To evaluate the anti-haze effect and visual outcome after intraoperative mitomycin C (MMC) use during photorefractive keratectomy (PRK) in myopia or myopic astigmatism patients."5.12Mitomycin C for the prevention of corneal haze in photorefractive keratectomy: a meta-analysis and trial sequential analysis. ( Chang, YM; Chien, KH; Lee, CH; Liang, CM; Weng, TH, 2021)
"The results show the efficacy of mitomycin-C in preventing corneal haze after treatment of high myopia with PRK."5.11Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study. ( Fotouhi, A; Hashemi, H; Kheiltash, A; Taheri, SM, 2004)
"To evaluate the results of the prophylactic use of mitomycin-C to inhibit haze formation after excimer laser photorefractive keratectomy (PRK) for medium and high myopia in eyes that were not good candidates for laser in situ keratomileusis (LASIK)."5.10Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. ( Carones, F; Scandola, E; Vacchini, L; Vigo, L, 2002)
"This review details the current understanding of the mechanism of action and corneal effects of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive keratectomy (PRK), and includes discussion of available information on dosage and exposure time recommended for MMC during PRK."5.05Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK. ( Carlos de Oliveira, R; Wilson, SE, 2020)
"02% mitomycin C (MMC) used for up to 2 minutes after surface ablation for correction of myopia."4.87Meta-analysis of clinical outcomes comparing surface ablation for correction of myopia with and without 0.02% mitomycin C. ( Chen, SH; Feng, YF; Stojanovic, A; Wang, QM, 2011)
"Trabeculectomy with mitomycin C was the most common primary surgery performed in Thai patients with JOAG, and successfully reduced intraocular pressure without significant complications."4.31Treatment Outcomes for Juvenile Open Angle Glaucoma in Thailand. ( Annopawong, K; Friedman, DS; Seresirikachorn, K; Thiamthat, W; Vu, DM; Wanichwecharungruang, B, 2023)
"Postoperative complications related to overfiltration were less frequent after canaloplasty with mitomycin C."4.12Is canaloplasty with mitomycin c a safe procedure in myopic glaucoma? ( Dietlein, TS; Dooling, V; Lappas, A, 2022)
"This work aimed to study the changes in corneal optical density measured with confocal microscopy in eyes treated with laser-assisted subepithelial keratectomy (LASEK) and intraoperative mitomycin C (MMC) to correct myopia."4.02Effect of Laser-assisted Subepithelial Keratectomy with Mitomycin C on Corneal Optical Density Measured with Confocal Microscopy. ( Cañadas, P; Cañones-Zafra, R; Garcia-Gonzalez, M; Gros-Otero, J; Rodriguez-Perez, I; Teus, MA, 2021)
"ASLA-SCHWIND TransPRK without mitomycin-C appears to be safe as well as effective and accurate for high myopia."4.02Efficacy and safety of single-step transepithelial photorefractive keratectomy with the all-surface laser ablation SCHWIND platform without mitomycin-C for high myopia: A retrospective study of 69 eyes. ( Bloch, F; El Nar, A; Giral, JB; Goetz, C; Lhuillier, L; Perone, JM; Sot, M; Vermion, JC; Zevering, Y, 2021)
"To compare efficacy and safety of single-step transepithelial photorefractive keratectomy (PRK) with or without mitomycin C (MMC) in patients with mild to moderate myopia."3.88Comparison of Single-Step Transepithelial Photorefractive Keratectomy With or Without Mitomycin C in Mild to Moderate Myopia. ( Adib-Moghaddam, S; Grentzelos, MA; Kymionis, GD; Soleyman-Jahi, S; Tefagh, G; Tofighi, S, 2018)
"Photorefractive keratectomy (PRK) is a safe and effective surgical keratorefractive technique which is done with the application of mitomycin-C (MMC) in cases of high myopia to prevent the formation of corneal haze This study was conducted to evaluate 3-year visual acuity and quality outcomes of PRK-MMC in high myopia."3.85Photorefractive Keratectomy With Mitomycin-C for High Myopia: Three Year Follow-Up Results. ( Asgari, S; Hashemi, H; Pir, P; Salimi, Y, 2017)
"To longitudinally compare the visual and refractive outcomes and changes in corneal thickness between femtosecond-assisted sub-Bowmen keratomileusis (SBK) and photorefractive keratectomy (PRK) with mitomycin C in eyes with high myopia."3.85Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia. ( Chan, TCY; Jhanji, V; Mak, S; Yu, MCY, 2017)
"To evaluate the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia."3.85Long-term Follow-up of LASEK With Mitomycin C Performed to Correct Myopia in Thin Corneas. ( Drake Rodriguez-Casanova, P; Garcia-Gonzalez, M; Rodero, A; Rodriguez-Perez, I; Teus, MA, 2017)
"The purpose of this study was to evaluate the predictability and stability of laser-assisted subepithelial keratectomy (LASEK) with mitomycin C (MMC) in correction of high myopia (≤-6."3.85Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia. ( Chen, IN; Fan, MCY; Iu, LPL; Lai, JSM, 2017)
"To compare the variance in manifest refraction spherical equivalent (MRSE) after photorefractive keratectomy (PRK) with mitomycin-C (MMC), PRK without MMC, and laser in situ keratomileusis (LASIK) for the treatment of myopic astigmatism."3.80Effect of mitomycin-C on the variance in refractive outcomes after photorefractive keratectomy. ( Hamilton, DR; Huang, D; Sy, ME; Yeroushalmi, A; Zhang, L, 2014)
"To examine the refractive and visual outcome of laser-assisted subepithelial keratomileusis (LASEK) with mitomycin C(MMC) in eyes with myopic astigmatism ≥2."3.80Laser-assisted subepithelial keratomileusis with mitomycin C for myopic astigmatism ≥2.00 diopters using a Zeiss MEL 80 Excimer. ( Ardjomand, N; El-Shabrawi, Y; Frings, A; Vidic, B, 2014)
"To evaluate corneal biomechanical properties and intraocular pressure (IOP) after photorefractive keratectomy (PRK) with or without mitomycin-C (MMC) 0."3.78Effect of photorefractive keratectomy with mitomycin-C on corneal biomechanical features. ( Azimzadeh, A; Esfandiari, H; Feizi, S; Zare, M, 2012)
"To report the use of photorefractive keratectomy (PRK) with mitomycin-C (MMC) to treat concomitant myopia and visually significant infiltrates associated with epidemic keratoconjunctivitis (EKC)."3.78Photorefractive keratectomy with mitomycin-C for the combined treatment of myopia and subepithelial infiltrates after epidemic keratoconjunctivitis. ( Alevi, D; Barsam, A; Donnenfeld, ED; Kruh, J; Perry, HD; Prince, J, 2012)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) for the treatment of severe pediatric anisometropia and amblyopia resistant to more conservative treatment modalities."3.78Pediatric PRK (PhotoRefractive Keratectomy) with Mitomycin C (MCC) for Persistent Anisometropic Amblyopia. A Case Report. ( Arnold, RW; Crawford, CM; Frazier, TC; Mazzoli, RA; Raymond, WR; Torres, MF, 2012)
"To report topography-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) after penetrating keratoplasty for keratoconus."3.75Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report. ( Alves, MR; Barreto, J; Bechara, SJ; Nakano, M; Netto, MV; Reis, A, 2009)
"To retrospectively assess risk factors other than high myopia for corneal haze in patients who had conventional photorefractive keratectomy (PRK) without mitomycin-C (MMC)."3.74Astigmatism: risk factor for postoperative corneal haze in conventional myopic photorefractive keratectomy. ( Brunstetter, T; Rogers, S; Sheridan, MV; Thomas, KE, 2008)
"We report a case of controlled buccal pemphigus vulgaris with compound moderate myopia with astigmatism that was treated with photorefractive keratectomy with mitomycin-C (PRK+MMC) in both eyes."3.74Photorefractive keratectomy with mitomycin-C for the treatment of compound moderate myopia with astigmatism in buccal pemphigus vulgaris. ( Kheiltash, A; Taheri, SM, 2007)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with intraoperative mitomycin C (MMC) after deep anterior lamellar keratoplasty (DALK) for keratoconus."3.74Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus. ( Leccisotti, A, 2008)
"To evaluate the efficacy and safety of prophylactic mitomycin C (MMC) during photorefractive keratectomy (PRK) over LASIK flaps for the treatment of residual refractive errors following LASIK."3.74Photorefractive keratectomy with 0.02% mitomycin C for treatment of residual refractive errors after LASIK. ( Drake, A; Herzig, S; Srinivasan, S, 2008)
"To compare the postoperative pain, visual recovery, and outcomes of flap-on and flap-off epithelial laser in situ keratomileusis (epi-LASIK) with mitomycin-C (MMC)."2.76Wavefront-guided epithelial laser in situ keratomileusis with mitomycin-C for myopia and myopic astigmatism: flap-on versus flap-off technique. ( Ang, RE; Hernandez, JA; Reyes, KB; Tchah, H, 2011)
" New findings regarding the penetration of MMC to the endothelium and into the aqueous humor may lead surgeons to reassess appropriate dosing and patient selection when the drug is used for surgery."2.46Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery. ( Shah, RA; Wilson, SE, 2010)
"Higher myopia was associated with increased haze severity at 3 months (OR, 1."1.56Refractive outcomes, corneal haze and endothelial cell loss after myopic photorefractive keratectomy in an Asian population: The Singapore Armed Forces' experience. ( Ang, BCH; Lim, EWL; Nah, GKM; Tan, MCL; Tan, MMH; Toh, ZH; Yap, SC; Zhao, PSB, 2020)
"Mitomycin C was applied immediately after laser ablation."1.35Mitomycin C in photorefractive keratectomy. ( Gimbel, HV; Kaye, GB; Shalaby, A, 2009)
" However, for moderate myopia and shallow depth, low dosing appears to be equally effective."1.35Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia. ( Krueger, RR; Thornton, I; Xu, M, 2008)
"Mitomycin C treatment induces apoptosis of keratocytes and myofibroblasts, but the predominate effect in inhibiting or treating haze appears to be at the level of blocked replication of keratocytes or other progenitor cells of myofibroblasts."1.33Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. ( Gupta, PC; Mohan, RR; Netto, MV; Sharma, A; Sinha, S; Wilson, SE, 2006)
"Mitomycin C was placed in contact with the ablation zone for 75 seconds with an imbibed microsponge."1.33Comparison of laser epithelial keratomileusis with and without the use of mitomycin C. ( Argento, C; Cosentino, MJ; Ganly, M, 2006)

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (2.83)18.2507
2000's42 (39.62)29.6817
2010's49 (46.23)24.3611
2020's12 (11.32)2.80

Authors

AuthorsStudies
Hashemi, H4
Pakbin, M1
Pakravan, M1
Fotouhi, A2
Jafarzadehpur, E1
Aghamirsalim, M1
Khabazkhoob, M1
Ouerdane, Y1
Zaazouee, MS1
Mohamed, MEA1
Hasan, MT1
Hamdy, M1
Ghoneim, AM1
Gbreel, MI1
Ibrahim, AM1
Ragab, KM1
Nourelden, AZ1
Giral, JB1
Bloch, F1
Sot, M1
Zevering, Y1
El Nar, A1
Vermion, JC1
Goetz, C1
Lhuillier, L1
Perone, JM1
Dooling, V1
Lappas, A1
Dietlein, TS1
Seresirikachorn, K1
Thiamthat, W1
Annopawong, K1
Wanichwecharungruang, B1
Friedman, DS1
Vu, DM1
Mohammadi, SF2
Abdolahinia, T2
Ashrafi, E2
Heydari, S1
Jamali, S1
Ang, BCH1
Yap, SC1
Toh, ZH1
Lim, EWL1
Tan, MMH1
Nah, GKM1
Zhao, PSB1
Tan, MCL1
Carlos de Oliveira, R1
Wilson, SE4
Lu, NJ1
Koppen, C1
Awwad, S1
Aslanides, MI1
Aslanides, IM1
Chen, SH2
Sudanaboina, P1
Murthy, SI1
Rathi, VM1
Chang, YM1
Liang, CM1
Weng, TH1
Chien, KH1
Lee, CH1
Gao, H1
Miles, TP1
Troche, R1
Murdoch, DM1
Koefoed, VF1
Cason, JB2
Cañadas, P3
Garcia-Gonzalez, M2
Gros-Otero, J1
Rodriguez-Perez, I2
Cañones-Zafra, R1
Teus, MA11
Liu, YC1
Rosman, M1
Mehta, JS1
Kaiserman, I2
Sadi, N1
Mimouni, M2
Sela, T2
Munzer, G2
Levartovsky, S1
Iu, LPL1
Fan, MCY1
Chen, IN1
Lai, JSM1
Pokroy, R1
Siedlecki, J1
Luft, N1
Kook, D1
Wertheimer, C1
Mayer, WJ1
Bechmann, M1
Wiltfang, R1
Priglinger, SG1
Sekundo, W1
Dirisamer, M1
Drake Rodriguez-Casanova, P1
Rodero, A1
Coelho, LM1
Sieiro, RO1
Adib-Moghaddam, S1
Soleyman-Jahi, S2
Tefagh, G1
Tofighi, S1
Grentzelos, MA1
Kymionis, GD6
Mehlan, J1
Linke, SJ1
Skevas, C1
Steinberg, J1
Giannakakis, K1
Katz, T1
Farahi, A1
Mehravaran, S2
Frings, A1
Vidic, B1
El-Shabrawi, Y1
Ardjomand, N1
Hofmeister, EM2
Bishop, FM2
Kaupp, SE2
Schallhorn, SC3
Diakonis, VF3
Kankariya, VP1
Kounis, G1
Pallikaris, AI2
Yoo, SH2
Pallikaris, IG2
Leccisotti, A3
Fields, SV1
Sia, RK1
Ryan, DS1
Edwards, JD1
Stutzman, RD1
Bower, KS1
Norouzi, N1
Mir-AbouTalebi, M1
Jabbarvand, M1
Nassiri, N4
Sheibani, K1
Safi, S1
Haghnegahdar, M1
Nassiri, S1
Panahi, N1
Sy, ME1
Zhang, L1
Yeroushalmi, A1
Huang, D1
Hamilton, DR1
Abdulaal, MR1
Wehbe, HA1
Awwad, ST1
Santhiago, MR2
Majmudar, PA3
Donaldson, KE1
Shtein, RM1
Verity, SM1
Farjo, AA1
Torricelli, AA1
Parede, TR1
Netto, MV5
Crestana, FP1
Bechara, SJ2
Chan, TCY1
Yu, MCY1
Mak, S1
Jhanji, V1
Tanaka, D1
Nakanishi, H1
Hangai, M1
Akagi, T1
Morooka, S1
Ikeda, HO1
Yoshimura, N1
Pinheiro, FI1
Araújo-Filho, I1
Meneses do Rego, AC1
Pereira de Azevedo, E1
Tabosa do Egito, ES1
Oréfice, F1
Alves de Souza Lima Filho, A1
Salimi, Y1
Pir, P1
Asgari, S1
Chen, WL2
Chang, HW1
Hu, FR2
Barreto, J2
Santo, R1
Bechara, S1
Kara-Jose, N1
Charisis, S1
Bouzoukis, DI1
Naoumidi, I1
Tsilimbaris, MK1
de Benito-Llopis, L8
Hernández-Verdejo, JL3
Zhao, LQ1
Wei, RL1
Ma, XY1
Zhu, H1
Thomas, KE1
Brunstetter, T1
Rogers, S1
Sheridan, MV1
Shalaby, A1
Kaye, GB1
Gimbel, HV1
Reis, A1
Nakano, M1
Alves, MR1
Mohammadpour, M1
Koch, DD1
Maloney, R1
Hardten, DR1
Dell, S1
Sweeney, AD1
Wang, L1
Gil-Cazorla, R1
Drake, P3
Wallau, AD2
Campos, M2
Kim, ST1
Koh, JW1
Yoon, GJ1
Yang, SW1
Virasch, VV1
Epstein, RJ2
Vaidya, NS1
Dennis, RF2
Kremer, I1
Ehrenberg, M1
Levinger, S1
Shah, RA1
de Benito Llopis, L1
Liu, A1
Manche, EE1
Fernandes, M1
Reddy, P1
Shah, SG1
Feng, YF1
Stojanovic, A1
Wang, QM1
Shen, EP1
Hsieh, YT1
Yeh, PT1
Wang, TJ1
Gambato, C3
Catania, AG1
Vujosevic, S1
Midena, E3
Ang, RE1
Reyes, KB1
Hernandez, JA1
Tchah, H1
Drake-Casanova, P1
Huisingh, C1
McGwin, G1
Zare, M1
Feizi, S1
Azimzadeh, A1
Esfandiari, H1
Alevi, D1
Barsam, A1
Kruh, J1
Prince, J1
Perry, HD1
Donnenfeld, ED1
Gomes, BA1
Smadja, D1
Espana, EM1
Ahn, ES1
Zhang, Y1
Chen, YG1
Xia, YJ1
Qi, H1
Shojaei, A1
Ramezanzadeh, M1
Almasi-Nasrabadi, M1
Rezazadeh, P1
Eslani, M1
Crawford, CM1
Frazier, TC1
Torres, MF1
Arnold, RW1
Mazzoli, RA1
Raymond, WR1
Carones, F1
Vigo, L1
Scandola, E1
Vacchini, L1
Taheri, SM2
Kheiltash, A2
Ghirlando, A2
Moretto, E1
Busato, F1
Kottler, UB1
Dick, HB1
Lee, DH1
Chung, HS1
Jeon, YC1
Boo, SD1
Yoon, YD1
Kim, JG1
Mohan, RR1
Sinha, S1
Sharma, A1
Gupta, PC1
Rajan, MS1
O'Brart, DP1
Patmore, A1
Marshall, J1
Argento, C1
Cosentino, MJ1
Ganly, M1
Randleman, JB2
Loft, ES1
Banning, CS1
Lynn, MJ1
Stulting, RD1
Nassaralla, BA1
McLeod, SD1
Nassaralla, JJ1
Pallikaris, A1
Markomanolakis, MM1
Ortega, M1
Cheng, AC1
Wong, VW1
Rao, SK1
Lam, DS1
Thornton, I2
Puri, A1
Xu, M2
Krueger, RR3
Goldsberry, DH1
Epstein, RH1
Holley, G1
Edelhauser, HF1
Miotto, S1
Cortese, M1
Salvi, R1
Gamaly, TO1
El Danasoury, A1
El Maghraby, A1
Lacayo, GO1
Srinivasan, S1
Drake, A1
Herzig, S1
Sánchez-Pina, JM1
Fuentes, I1
Farahangiz, S1
Rahnavardi, M1
Rahmani, L1
Utz, VM1
Gupta, N1
Weinreb, RN1
Morales, J1
Good, D1
Cheng, Z1
Li, J1
Cai, K1
Li, R1
Li, H1
Qin, X1
Maldonado, MJ1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 1 Study of in Vivo Confocal Microscope to Evaluate the Corneal Wound Healing After Various Ocular Surgeries[NCT00491439]120 participants (Actual)Observational2007-04-30Completed
Two Years Follow up of Corneal Cor Cross-linking and Refractive Surface Ablation in Patients With Asymmetric Corneal Topography[NCT02943967]44 participants (Actual)Interventional2010-01-31Completed
Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C.[NCT00599950]Phase 410 participants (Actual)Interventional2007-01-31Completed
Epi-LASIK : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma.[NCT00599690]10 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for mitomycin and Myopia

ArticleYear
Mitomycin C application after photorefractive keratectomy in high, moderate, or low myopia: Systematic review and meta-analysis.
    Indian journal of ophthalmology, 2021, Volume: 69, Issue:12

    Topics: Alkylating Agents; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Keratectomy

2021
Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK.
    Experimental eye research, 2020, Volume: 200

    Topics: Alkylating Agents; Corneal Opacity; Corneal Stroma; Fibrosis; Humans; Lasers, Excimer; Mitomycin; My

2020
Mitomycin C for the prevention of corneal haze in photorefractive keratectomy: a meta-analysis and trial sequential analysis.
    Acta ophthalmologica, 2021, Volume: 99, Issue:6

    Topics: Corneal Opacity; Cross-Linking Reagents; Humans; Mitomycin; Myopia; Photorefractive Keratectomy; Pos

2021
Mitomycin-C in corneal surface excimer laser ablation techniques: a report by the American Academy of Ophthalmology.
    Ophthalmology, 2015, Volume: 122, Issue:6

    Topics: Academies and Institutes; Alkylating Agents; Combined Modality Therapy; Cornea; Corneal Surgery, Las

2015
Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery.
    Current opinion in ophthalmology, 2010, Volume: 21, Issue:4

    Topics: Alkylating Agents; Animals; Astigmatism; Combined Modality Therapy; Corneal Opacity; Humans; Hyperop

2010
Meta-analysis of clinical outcomes comparing surface ablation for correction of myopia with and without 0.02% mitomycin C.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2011, Volume: 27, Issue:7

    Topics: Alkylating Agents; Cornea; Corneal Topography; Dose-Response Relationship, Drug; Humans; Keratectomy

2011
[Mitomycin C in refractive corneal surface surgery with the excimer laser: first experience and review of the literature].
    Klinische Monatsblatter fur Augenheilkunde, 2005, Volume: 222, Issue:6

    Topics: Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Corneal Opacity; Humans; Intracellular S

2005
Surface ablation.
    International ophthalmology clinics, 2008,Winter, Volume: 48, Issue:1

    Topics: Alkylating Agents; Corneal Stroma; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Mitomycin

2008

Trials

24 trials available for mitomycin and Myopia

ArticleYear
Effect of Short Versus Long-Term Steroid on Corneal Haze After Photorefractive Keratectomy: A Randomized, Double-Masked Clinical Trial.
    American journal of ophthalmology, 2022, Volume: 235

    Topics: Adult; Fluorometholone; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Keratectomy; Pro

2022
Long-term effects of mitomycin-C on residual aberration and optical quality after photorefractive keratectomy in eyes with low to moderate myopia.
    Journal of cataract and refractive surgery, 2019, Volume: 45, Issue:9

    Topics: Adolescent; Adult; Alkylating Agents; Contrast Sensitivity; Corneal Wavefront Aberration; Female; Fo

2019
Effect of intraoperative mitomycin-C application on epithelial regeneration after transepithelial photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2021, Feb-01, Volume: 47, Issue:2

    Topics: Alkylating Agents; China; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Keratectomy; P

2021
The effects of mitomycin C on tear function after photorefractive keratectomy: a contralateral comparative study.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2013, Volume: 29, Issue:4

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Corneal Stroma; Double-Blind Method; Fluorophot

2013
Randomized dose-response analysis of mitomycin-C to prevent haze after photorefractive keratectomy for high myopia.
    Journal of cataract and refractive surgery, 2013, Volume: 39, Issue:9

    Topics: Adult; Alkylating Agents; Cell Count; Corneal Endothelial Cell Loss; Corneal Opacity; Dose-Response

2013
Contralateral-eye study of surface refractive treatments: clinical and confocal microscopy evaluation.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:2

    Topics: Adult; Alkylating Agents; Cell Count; Combined Modality Therapy; Cornea; Corneal Keratocytes; Endoth

2014
The U.S. Army Surface Ablation Study: comparison of PRK, MMC-PRK, and LASEK in moderate to high myopia.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2014, Volume: 30, Issue:4

    Topics: Adult; Alkylating Agents; Cell Count; Combined Modality Therapy; Cornea; Endothelium, Corneal; Femal

2014
Effects of mitomycin-C on tear film, corneal biomechanics, and surface irregularity in mild to moderate myopic surface ablation: preliminary results.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:6

    Topics: Adult; Alkylating Agents; Biomechanical Phenomena; Cornea; Double-Blind Method; Elasticity; Female;

2014
Alcohol-assisted debridement in PRK with intraoperative mitomycin C.
    Optometry and vision science : official publication of the American Academy of Optometry, 2014, Volume: 91, Issue:9

    Topics: Adult; Alkylating Agents; Cell Count; Corneal Keratocytes; Corneal Stroma; Debridement; Endothelium,

2014
Intraocular straylight before and after low myopic photorefractive keratectomy with and without mitomycin C.
    Arquivos brasileiros de oftalmologia, 2016, Volume: 79, Issue:2

    Topics: Administration, Ophthalmic; Adult; Corneal Diseases; Corneal Wavefront Aberration; Cross-Linking Rea

2016
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK.
    The British journal of ophthalmology, 2009, Volume: 93, Issue:12

    Topics: Adult; Biomechanical Phenomena; Combined Modality Therapy; Contrast Sensitivity; Cornea; Corneal Opa

2009
Wavefront-guided epithelial laser in situ keratomileusis with mitomycin-C for myopia and myopic astigmatism: flap-on versus flap-off technique.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:6

    Topics: Aberrometry; Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Contrast Sensitivity;

2011
[Effect of mitomycin C on corneal regrowth after laser-assisted sub-epithelial keratectomy (LASEK)].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:7

    Topics: Adult; Cell Division; Corneal Opacity; Female; Fibroblasts; Growth Inhibitors; Humans; Intraoperativ

2011
Comparison of Tear cytokines and clinical outcomes between off-flap and on-flap epi-LASIK with mitomycin C.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2012, Volume: 28, Issue:9

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Cytokines; Double-Blind Method; Eye Pain; Eye P

2012
Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia.
    Journal of cataract and refractive surgery, 2013, Volume: 39, Issue:2

    Topics: Adult; Alkylating Agents; Cell Count; Cornea; Corneal Opacity; Double-Blind Method; Endothelium, Cor

2013
Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:12

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Cornea; Corneal Opacity; Double-Blind M

2002
Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study.
    BMC ophthalmology, 2004, Sep-14, Volume: 4

    Topics: Adult; Antibiotics, Antineoplastic; Corneal Opacity; Humans; Lasers, Excimer; Middle Aged; Mitomycin

2004
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
    Ophthalmology, 2005, Volume: 112, Issue:2

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Contrast Sensitivity; Cornea; Corneal O

2005
Alterations in endothelial cell density after photorefractive keratectomy with adjuvant mitomycin.
    American journal of ophthalmology, 2007, Volume: 144, Issue:1

    Topics: Alkylating Agents; Cell Count; Combined Modality Therapy; Double-Blind Method; Endothelium, Corneal;

2007
Long-term effects on corneal keratocytes of mitomycin C during photorefractive keratectomy: a randomized contralateral eye confocal microscopy study.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:9 Suppl

    Topics: Administration, Topical; Adult; Cell Count; Cornea; Corneal Opacity; Double-Blind Method; Female; Hu

2007
A prospective, randomized, contralateral eye comparison of epithelial laser in situ keratomileusis and photorefractive keratectomy in eyes prone to haze.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:9 Suppl

    Topics: Adult; Corneal Opacity; Epithelium, Corneal; Female; Humans; Keratomileusis, Laser In Situ; Lasers,

2007
Mitomycin C in photorefractive keratectomy: effect on epithelialization and predictability.
    Cornea, 2008, Volume: 27, Issue:3

    Topics: Administration, Topical; Adult; Alkylating Agents; Combined Modality Therapy; Double-Blind Method; E

2008
Corneal endothelial cell injury induced by mitomycin-C in photorefractive keratectomy: nonrandomized controlled trial.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Alkylating Agents; Cell Count; Cell Survival; Corneal Diseases; Endothelium, Corn

2008
Photorefractive keratectomy with mitomycin C versus LASIK in custom surgeries for myopia: a bilateral prospective randomized clinical trial.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:4

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Contrast Sensitivity; Double-Blind

2008

Other Studies

74 other studies available for mitomycin and Myopia

ArticleYear
Efficacy and safety of single-step transepithelial photorefractive keratectomy with the all-surface laser ablation SCHWIND platform without mitomycin-C for high myopia: A retrospective study of 69 eyes.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adult; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photorefractive Keratectomy; Prospe

2021
Is canaloplasty with mitomycin c a safe procedure in myopic glaucoma?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2022, Volume: 260, Issue:10

    Topics: Choroidal Effusions; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Mitomycin; Myopia

2022
Treatment Outcomes for Juvenile Open Angle Glaucoma in Thailand.
    Journal of glaucoma, 2023, 11-01, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Child; Child, Preschool; Cornea; Female; Follow-Up Studies; Glaucoma; Glaucoma, O

2023
Refractive outcomes, corneal haze and endothelial cell loss after myopic photorefractive keratectomy in an Asian population: The Singapore Armed Forces' experience.
    Clinical & experimental ophthalmology, 2020, Volume: 48, Issue:5

    Topics: Cornea; Endothelial Cells; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photorefractive Keratec

2020
Excimer laser phototherapeutic keratectomy with mitomycin C application to treat haze after myopic photorefractive keratectomy.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:12

    Topics: Alkylating Agents; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Kera

2020
Quality of Vision Following LASIK and PRK-MMC for Treatment of Myopia.
    Military medicine, 2022, 08-25, Volume: 187, Issue:9-10

    Topics: Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Keratecto

2022
Effect of Laser-assisted Subepithelial Keratectomy with Mitomycin C on Corneal Optical Density Measured with Confocal Microscopy.
    Optometry and vision science : official publication of the American Academy of Optometry, 2021, 04-01, Volume: 98, Issue:4

    Topics: Adult; Alkylating Agents; Biometry; Combined Modality Therapy; Cornea; Corneal Stroma; Female; Human

2021
Enhancement after Small-Incision Lenticule Extraction: Incidence, Risk Factors, and Outcomes.
    Ophthalmology, 2017, Volume: 124, Issue:6

    Topics: Adult; Alkylating Agents; Cohort Studies; Corneal Stroma; Corneal Surgery, Laser; Female; Humans; In

2017
Corneal Breakthrough Haze After Photorefractive Keratectomy With Mitomycin C: Incidence and Risk Factors.
    Cornea, 2017, Volume: 36, Issue:8

    Topics: Adult; Alkylating Agents; Corneal Opacity; Female; Humans; Hyperopia; Incidence; Lasers, Excimer; Ma

2017
Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia.
    Medicine, 2017, Volume: 96, Issue:22

    Topics: Adult; Combined Modality Therapy; Female; Hong Kong; Humans; Keratectomy, Subepithelial, Laser-Assis

2017
Predictors of myopic photorefractive keratectomy retreatment.
    Journal of cataract and refractive surgery, 2017, Volume: 43, Issue:6

    Topics: Adult; Alkylating Agents; Female; Humans; Male; Mitomycin; Myopia; Photorefractive Keratectomy; Retr

2017
Enhancement After Myopic Small Incision Lenticule Extraction (SMILE) Using Surface Ablation.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2017, Aug-01, Volume: 33, Issue:8

    Topics: Administration, Topical; Adult; Corneal Stroma; Corneal Surgery, Laser; Cross-Linking Reagents; Feas

2017
Long-term Follow-up of LASEK With Mitomycin C Performed to Correct Myopia in Thin Corneas.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2017, Dec-01, Volume: 33, Issue:12

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Cornea; Corneal Pachymetry; Corneal Topography;

2017
Mitomycin C 0.02 and 0.002% efficacy in preventing haze after photorefractive keratectomy.
    International ophthalmology, 2019, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Dose-Response Relationship, Drug; Female; Foll

2019
Comparison of Single-Step Transepithelial Photorefractive Keratectomy With or Without Mitomycin C in Mild to Moderate Myopia.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2018, Jun-01, Volume: 34, Issue:6

    Topics: Adult; Alkylating Agents; Cell Count; Contrast Sensitivity; Corneal Wavefront Aberration; Endotheliu

2018
Safety and complications after three different surface ablation techniques with mitomycin C: a retrospective analysis of 2757 eyes.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019, Volume: 257, Issue:1

    Topics: Administration, Topical; Adult; Female; Humans; Intraoperative Period; Lasers, Excimer; Male; Mitomy

2019
Laser-assisted subepithelial keratomileusis with mitomycin C for myopic astigmatism ≥2.00 diopters using a Zeiss MEL 80 Excimer.
    International ophthalmology, 2014, Volume: 34, Issue:2

    Topics: Adult; Alkylating Agents; Astigmatism; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excime

2014
Reply: To PMID 23830559.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:3

    Topics: Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photor

2014
Mitomycin-C in photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:3

    Topics: Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photor

2014
Effect of mitomycin-C on the variance in refractive outcomes after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:12

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Corneal Stroma; Humans; Keratomile

2014
One-step transepithelial photorefractive keratectomy with mitomycin C as an early treatment for LASIK flap buttonhole formation.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2015, Volume: 31, Issue:1

    Topics: Adult; Cross-Linking Reagents; Female; Follow-Up Studies; Humans; Keratomileusis, Laser In Situ; Mal

2015
Refractive surgical problem: December consultation #1.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:12

    Topics: Adult; Alkylating Agents; Corneal Endothelial Cell Loss; Endothelium, Corneal; Epikeratophakia; Fema

2014
Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia.
    The British journal of ophthalmology, 2017, Volume: 101, Issue:3

    Topics: Adult; Analysis of Variance; Cornea; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer;

2017
Influence of high myopia on outcomes of trabeculectomy with mitomycin C in patients with primary open-angle glaucoma.
    Japanese journal of ophthalmology, 2016, Volume: 60, Issue:6

    Topics: Aged; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Ag

2016
New drug delivery system for corneal administration of mitomycin-C.
    Journal of cataract and refractive surgery, 2016, Volume: 42, Issue:8

    Topics: Alkylating Agents; Drug Delivery Systems; Humans; Lasers, Excimer; Mitomycin; Myopia; Perioperative

2016
Photorefractive Keratectomy With Mitomycin-C for High Myopia: Three Year Follow-Up Results.
    Acta medica Iranica, 2017, Volume: 55, Issue:1

    Topics: Adult; Contrast Sensitivity; Cornea; Female; Follow-Up Studies; Humans; Lasers, Excimer; Male; Mitom

2017
In vivo confocal microscopic evaluation of corneal wound healing after epi-LASIK.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:6

    Topics: Adult; Alkylating Agents; Astigmatism; Epithelium, Corneal; Humans; Keratomileusis, Laser In Situ; L

2008
Synergistic effect of ethanol and mitomycin C on corneal stroma.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:6

    Topics: Actins; Animals; Cell Count; Corneal Stroma; Drug Combinations; Drug Synergism; Epithelium, Corneal;

2008
Effects of topical mitomycin C on the ciliary body and intraocular pressure after PRK: an experimental study.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:6

    Topics: Administration, Topical; Alkylating Agents; Animals; Ciliary Body; Intraocular Pressure; Lasers, Exc

2008
Comparison between three- and six-month postoperative refractive and visual results after laser epithelial keratomileusis with mitomycin C.
    American journal of ophthalmology, 2009, Volume: 147, Issue:1

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Keratectomy,

2009
Effect of intraoperative mitomycin-C on healthy corneal endothelium after laser-assisted subepithelial keratectomy.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Alkylating Agents; Astigmatism; Cell Count; Endothelium, Corneal; Female; Follow-

2008
Astigmatism: risk factor for postoperative corneal haze in conventional myopic photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:12

    Topics: Adult; Alkylating Agents; Astigmatism; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Middl

2008
Mitomycin C in photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2009, Volume: 25, Issue:1 Suppl

    Topics: Alkylating Agents; Combined Modality Therapy; Cornea; Corneal Opacity; Humans; Lasers, Excimer; Mito

2009
Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2009, Volume: 25, Issue:1 Suppl

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Corneal Topography; Female; Humans

2009
Photorefractive keratectomy with and without mitomycin-C.
    Cornea, 2009, Volume: 28, Issue:6

    Topics: Humans; Mitomycin; Myopia; Photorefractive Keratectomy

2009
Wavefront-guided photorefractive keratectomy in eyes with prior radial keratotomy: a multicenter study.
    Ophthalmology, 2009, Volume: 116, Issue:9

    Topics: Adult; Combined Modality Therapy; Corneal Topography; Female; Follow-Up Studies; Humans; Hyperopia;

2009
Comparison between femtosecond laser-assisted sub-Bowman keratomileusis vs laser subepithelial keratectomy to correct myopia.
    American journal of ophthalmology, 2009, Volume: 148, Issue:6

    Topics: Adolescent; Adult; Corneal Surgery, Laser; Follow-Up Studies; Humans; Keratectomy, Subepithelial, La

2009
Clinical outcomes of epi-LASIK: 1-year results of on- and off-flap procedures with and without mitomycin-C.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:5

    Topics: Adult; Corneal Opacity; Corneal Topography; Female; Humans; Keratomileusis, Laser In Situ; Male; Mit

2010
Reduced application time for prophylactic mitomycin C in photorefractive keratectomy.
    Ophthalmology, 2010, Volume: 117, Issue:5

    Topics: Adult; Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia;

2010
Delayed epithelial healing following photorefractive keratectomy with mitomycin C treatment.
    Acta ophthalmologica, 2012, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Alkylating Agents; Anti-Bacterial Agents; Combined Modality Therapy; Debridement;

2012
Efficacy of surface ablation retreatments using mitomycin C.
    American journal of ophthalmology, 2010, Volume: 150, Issue:3

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Cornea; Humans; Intraoperative Com

2010
Keratocyte density after laser-assisted subepithelial keratectomy with mitomycin C.
    American journal of ophthalmology, 2010, Volume: 150, Issue:5

    Topics: Adult; Alkylating Agents; Cell Count; Combined Modality Therapy; Corneal Stroma; Follow-Up Studies;

2010
Visually significant haze after retreatment with photorefractive keratectomy with mitomycin-C following laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:9

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Corneal Opacity; Female; Humans; Keratomileusis

2010
One-year outcome of bilateral randomised prospective clinical trial comparing photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK).
    The British journal of ophthalmology, 2011, Volume: 95, Issue:3

    Topics: Combined Modality Therapy; Humans; Keratomileusis, Laser In Situ; Mitomycin; Myopia; Nucleic Acid Sy

2011
Comparison of in vivo confocal microscopic findings between epi-LASIK procedures with different management of the epithelial flaps.
    Investigative ophthalmology & visual science, 2011, Jun-01, Volume: 52, Issue:6

    Topics: Adult; Alkylating Agents; Astigmatism; Epithelium, Corneal; Female; Humans; Keratomileusis, Laser In

2011
Wavefront-optimized surface ablation with the Allegretto Wave Eye-Q excimer laser platform: 12-month visual and refractive results.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2011, Volume: 27, Issue:11

    Topics: Adult; Algorithms; Alkylating Agents; Astigmatism; Cornea; Female; Humans; Lasers, Excimer; Male; Mi

2011
Keratocyte density 3 months, 15 months, and 3 years after corneal surface ablation with mitomycin C.
    American journal of ophthalmology, 2012, Volume: 153, Issue:1

    Topics: Adult; Alkylating Agents; Astigmatism; Cell Count; Combined Modality Therapy; Corneal Keratocytes; C

2012
Keratocyte density 3 months, 15 months, and 3 years after corneal surface ablation with mitomycin C.
    American journal of ophthalmology, 2012, Volume: 153, Issue:5

    Topics: Alkylating Agents; Corneal Keratocytes; Humans; Keratectomy, Subepithelial, Laser-Assisted; Lasers,

2012
Effect of photorefractive keratectomy with mitomycin-C on corneal biomechanical features.
    Current eye research, 2012, Volume: 37, Issue:6

    Topics: Adult; Alkylating Agents; Biomechanical Phenomena; Combined Modality Therapy; Cornea; Elasticity; Fe

2012
Photorefractive keratectomy with mitomycin-C for the combined treatment of myopia and subepithelial infiltrates after epidemic keratoconjunctivitis.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:6

    Topics: Aberrometry; Adenoviridae; Adenovirus Infections, Human; Administration, Topical; Adult; Alkylating

2012
Very late-onset corneal scar triggered by trauma after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:9

    Topics: Alkylating Agents; Cornea; Corneal Injuries; Corneal Opacity; Eye Injuries; Female; Glucocorticoids;

2012
Pediatric PRK (PhotoRefractive Keratectomy) with Mitomycin C (MCC) for Persistent Anisometropic Amblyopia. A Case Report.
    Binocular vision & strabology quarterly, Simms-Romano's, 2012, Volume: 27, Issue:4

    Topics: Amblyopia; Child; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Keratectomy; Prospecti

2012
Mitomycin C in highly myopic eyes.
    Ophthalmology, 2006, Volume: 113, Issue:2

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Cornea; Corneal Opacity; Humans; Lasers, Excim

2006
Photorefractive keratectomy with intraoperative mitomycin-C application.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Combined Modality Therapy; Cornea; Female; Humans; Intraoperativ

2005
Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2006, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Cell Count; Cell Proliferation; Cornea; Corneal Opacity; Disease Models, Animal;

2006
Cellular effects of mitomycin-C on human corneas after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:10

    Topics: Alkylating Agents; Cell Movement; Cornea; Epithelial Cells; Fibroblasts; Humans; Lasers, Excimer; Mi

2006
Comparison of laser epithelial keratomileusis with and without the use of mitomycin C.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2006, Volume: 22, Issue:8

    Topics: Adult; Antibiotics, Antineoplastic; Epithelium, Corneal; Female; Follow-Up Studies; Humans; Incidenc

2006
Outcomes of wavefront-optimized surface ablation.
    Ophthalmology, 2007, Volume: 114, Issue:5

    Topics: Adult; Alkylating Agents; Cornea; Female; Humans; Keratectomy, Subepithelial, Laser-Assisted; Kerato

2007
Prophylactic mitomycin C to inhibit corneal haze after photorefractive keratectomy for residual myopia following radial keratotomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:3

    Topics: Adult; Alkylating Agents; Cell Count; Corneal Opacity; Endothelium, Corneal; Female; Humans; Keratot

2007
Effect of mitomycin-C on the corneal endothelium during excimer laser surface ablation.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Adult; Alkylating Agents; Cell Count; Endothelium, Corneal; Follow-Up Studies; Humans; Keratectomy,

2007
Repositioning of free cap four days after LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:6

    Topics: Adult; Cornea; Drug Therapy, Combination; Humans; Intraoperative Complications; Keratomileusis, Lase

2007
Laser-assisted subepithelial keratectomy with MMC to treat post-LASIK myopic regression.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:10

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Cornea; Female; Humans; Keratectomy, Subepithel

2007
Photorefractive keratectomy with mitomycin-C for the treatment of compound moderate myopia with astigmatism in buccal pemphigus vulgaris.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:10

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Female; Humans; Lasers, Excimer; M

2007
Low-dose mitomycin C as a prophylaxis for corneal haze in myopic surface ablation.
    American journal of ophthalmology, 2007, Volume: 144, Issue:5

    Topics: Adolescent; Adult; Cornea; Corneal Opacity; Female; Follow-Up Studies; Humans; Keratectomy, Subepith

2007
Effect of mitomycin C on the corneal endothelium when used for corneal subepithelial haze prophylaxis following photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:7

    Topics: Cell Count; Corneal Opacity; Endothelium, Corneal; Humans; Lasers, Excimer; Mitomycin; Myopia; Nucle

2007
Photorefractive keratectomy with 0.02% mitomycin C for treatment of residual refractive errors after LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:1

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Female; Humans; Keratomileusis, Laser In Situ;

2008
Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:1

    Topics: Adult; Alkylating Agents; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefracti

2008
Stability of laser epithelial keratomileusis with and without mitomycin C performed to correct myopia in thin corneas: a 15-month follow-up.
    American journal of ophthalmology, 2008, Volume: 145, Issue:5

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Cornea; Female; Follow-Up Studies; Humans; Kera

2008
Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus.
    Cornea, 2008, Volume: 27, Issue:4

    Topics: Adult; Alkylating Agents; Astigmatism; Cell Count; Combined Modality Therapy; Corneal Topography; Co

2008
Management of irregular astigmatism following rotationally disoriented free cap after LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:4

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Corneal Stroma; Corneal Topography

2008
Filtering bleb infection as a complication of orthokeratology.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Contact Lenses; Drug Therapy, Combination

1997
Permanent glaucomatous visual loss after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:5

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Cornea; Dexamethasone; Filtering Surgery;

1998
[Effects of mitomycin C on haze after photorefractive keratectomy for myopia in rabbits].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1998, Volume: 34, Issue:6

    Topics: Animals; Dexamethasone; Female; Lasers, Excimer; Male; Microscopy, Electron, Scanning; Mitomycin; My

1998
Intraoperative MMC after excimer laser surgery for myopia.
    Ophthalmology, 2002, Volume: 109, Issue:5

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Epithelium, Corneal; Fibrosis; Humans; Intraop

2002