mitomycin has been researched along with Myelodysplastic Syndromes in 6 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report the case history of a patient with myelodyspasia occurring after neoadjuvant methotrexate, mitoxantrone and mitomycin C (triple M) chemotherapy with subsequent radiotherapy for locally advanced breast cancer." | 3.70 | Myelodysplastic syndrome as a complication of neo-adjuvant triple M chemotherapy and radiotherapy. ( Lowdell, CP; Partridge, SE, 1999) |
| "Of 1774 patients with breast cancer given mitoxantrone (MTZ) with methotrexate (n = 492) or with methotrexate and mitomycin C (n = 1282), nine developed MDS/AML after a median of 2." | 3.70 | Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma. ( Ashley, S; Kuan, A; Kulkarni, S; Mehta, J; Mitchell, P; Powles, R; Powles, T; Saso, R; Swansbury, GJ; Treleaven, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, F | 1 |
| Gao, C | 1 |
| Lu, J | 1 |
| Tatetsu, H | 1 |
| Williams, DA | 1 |
| Müller, LU | 1 |
| Cui, W | 1 |
| Chai, L | 1 |
| Korgaonkar, S | 1 |
| Ghosh, K | 1 |
| Vundinti, BR | 1 |
| Partridge, SE | 1 |
| Lowdell, CP | 1 |
| Saso, R | 1 |
| Kulkarni, S | 1 |
| Mitchell, P | 1 |
| Treleaven, J | 1 |
| Swansbury, GJ | 1 |
| Mehta, J | 1 |
| Powles, R | 1 |
| Ashley, S | 1 |
| Kuan, A | 1 |
| Powles, T | 1 |
| Uemura, M | 1 |
| Kasamatsu, Y | 1 |
| Sawada, M | 1 |
| Takemura, S | 1 |
| Sugino, S | 1 |
| Kondou, M | 1 |
| Shinohara, M | 1 |
| Takishita, M | 1 |
| Wada, M | 1 |
| Tuchihashi, N | 1 |
| Gotoh, T | 1 |
| Okagawa, K | 1 |
| Kosaka, M | 1 |
1 review available for mitomycin and Myelodysplastic Syndromes
| Article | Year |
|---|---|
[A case of secondary myelodysplastic syndrome following chemotherapy for lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitio | 1992 |
5 other studies available for mitomycin and Myelodysplastic Syndromes
| Article | Year |
|---|---|
Leukemic survival factor SALL4 contributes to defective DNA damage repair.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chromosomal Instability; Cluster Analysis; | 2016 |
Clinical, genetic and cytogenetic study of Fanconi anemia in an Indian population.
Topics: Adolescent; Carcinoma, Squamous Cell; Cells, Cultured; Child; Child, Preschool; Chromosome Breakage; | 2010 |
Myelodysplastic syndrome as a complication of neo-adjuvant triple M chemotherapy and radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Methotrexate; Midd | 1999 |
Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neopl | 2000 |
[Myelodysplastic syndrome (RAEB-T) occurring after adjuvant chemotherapy for colon and rectum cancers].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Cytarabine; DN | 1990 |