Page last updated: 2024-11-06

mitomycin and Multiple Sclerosis

mitomycin has been researched along with Multiple Sclerosis in 6 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Multiple sclerosis is associated with iridocyclitis, intermediate uveitis, retinal periphlebitis, and optic neuritis."1.37Bilateral rubeosis iridis and rubeotic glaucoma due to peripheral occlusive vasculitis associated with multiple sclerosis. ( Deane, J; Dharmasena, A; Turner, SJ, 2011)
" Dose-response curves and kinetic profiles for the IgSC responses induced by pokeweed mitogen (PWM), a polyclonal B cell activator, were similar for CSF cells (CSFC) and peripheral blood mononuclear cells (PBMC)."1.27B cell activation in multiple sclerosis. ( Levinson, AI; Lisak, RP; Sandberg, M; Zweiman, B, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Turner, SJ1
Dharmasena, A1
Deane, J1
Antel, JP1
Peeples, DM1
Reder, AT1
Arnason, BG1
Newton, MS1
Steel, CM1
Evans, HJ1
Pentland, B1
Hirsch, RL1
Sandberg, M1
Levinson, AI1
Zweiman, B1
Lisak, RP1

Reviews

1 review available for mitomycin and Multiple Sclerosis

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Trials

1 trial available for mitomycin and Multiple Sclerosis

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

5 other studies available for mitomycin and Multiple Sclerosis

ArticleYear
Bilateral rubeosis iridis and rubeotic glaucoma due to peripheral occlusive vasculitis associated with multiple sclerosis.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:5

    Topics: Acetazolamide; Adult; Glaucoma, Neovascular; Humans; Immunosuppressive Agents; Iritis; Light Coagula

2011
Analysis of T regulator cell surface markers and functional properties in multiple sclerosis.
    Journal of neuroimmunology, 1984, Volume: 6, Issue:2

    Topics: Adult; Antigens, Surface; Concanavalin A; Humans; Immunoglobulin G; Mitomycin; Mitomycins; Monocytes

1984
Spontaneous and mutagen induced sister chromatid exchange in multiple sclerosis.
    Journal of medical genetics, 1983, Volume: 20, Issue:5

    Topics: Adult; Crossing Over, Genetic; DNA Repair; Ethyl Methanesulfonate; Female; Humans; In Vitro Techniqu

1983
Defective autologous mixed lymphocyte reactivity in multiple sclerosis.
    Clinical and experimental immunology, 1986, Volume: 64, Issue:1

    Topics: Autoimmune Diseases; Humans; In Vitro Techniques; Lymphocyte Culture Test, Mixed; Mitomycin; Mitomyc

1986
B cell activation in multiple sclerosis.
    Acta neurologica Scandinavica, 1986, Volume: 74, Issue:6

    Topics: B-Lymphocytes; Cells, Cultured; Cerebrospinal Fluid; Humans; Immunoglobulin G; Lymphocyte Activation

1986