Page last updated: 2024-11-06

mitomycin and Mouth Neoplasms

mitomycin has been researched along with Mouth Neoplasms in 26 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Mouth Neoplasms: Tumors or cancer of the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"Twenty one patients with resectable oral cancer received two courses of induction chemotherapy with peplomycin (PEP), vincristine (VCR), mitomycin C (MMC) and cisplatin (CDDP)."2.68[Clinical and histological effect of induction chemotherapy with peplomycin, vincristine, mitomycin C and cis-platinum on oral squamous cell carcinomas]. ( Hayashido, Y; Hiranuma, T; Matsuya, T; Mima, T; Ogura, T; Sakai, T; Shirasuna, K; Usui, M, 1995)
"Ninety-seven patients with oral squamous cell carcinoma, treated preoperatively with radiotherapy in combination with chemotherapy or cetuximab, were included in this retrospective analysis."1.48P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC. ( Eder-Czembirek, C; Fuereder, T; Selzer, E; Sulzbacher, I, 2018)
"Oral squamous cell carcinoma (OSCC) may develop in young adults."1.43Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma. ( Braakhuis, BJ; Brakenhoff, RH; Flach, GB; Graveland, AP; Joenje, H; Leemans, CR; Nieuwint, AW; Oostra, AB, 2016)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's7 (26.92)18.2507
2000's10 (38.46)29.6817
2010's4 (15.38)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Patra, S1
Singh, A1
Praharaj, PP1
Mohanta, NK1
Jena, M1
Patro, BS1
Abusharha, A1
Patil, S1
Bhutia, SK1
Eder-Czembirek, C1
Sulzbacher, I3
Fuereder, T1
Selzer, E5
Budach, V2
Stromberger, C1
Poettgen, C1
Baumann, M1
Budach, W2
Grabenbauer, G1
Marnitz, S1
Olze, H1
Wernecke, KD1
Ghadjar, P1
Braakhuis, BJ1
Nieuwint, AW1
Oostra, AB1
Joenje, H1
Flach, GB1
Graveland, AP1
Brakenhoff, RH1
Leemans, CR1
Klug, C4
Berzaczy, D1
Voracek, M3
Nell, C1
Ploder, O2
Millesi, W5
Ewers, R4
Perisanidis, C1
Mittlböck, M1
Mitchell, D1
Czembirek, C1
Seemann, R1
Schopper, C1
Brown, TA1
Ridge, JA1
Goldberg, M1
Neuburg, J1
Glaser, C2
Schwarz, B1
Kermer, C3
Schmidberger, H1
Rave-Fränk, M1
Kim, S1
Hille, A1
Pradier, O1
Hess, CF1
Wutzl, A2
Kornek, G1
Poeschl, PW1
Oeckher, M1
Shintani, S1
Hino, S1
Nakashiro, K1
Hamakawa, H1
Kohno, N1
Ichikawa, G1
Nakazawa, E1
Kusunoki, M1
Nishiya, M1
Nishiyama, M1
Saeki, S1
Aogi, K1
Hirabayashi, N1
Toge, T1
Stuschke, M1
Dinges, S1
Jahnke, K1
Heselmann, I1
Unger, A1
Stüben, G1
Sack, H1
Shirasuna, K1
Ogura, T2
Mima, T1
Hiranuma, T2
Sakai, T1
Hayashido, Y2
Matsuya, T2
Usui, M1
Okura, M1
Adachi, T1
Aikawa, T1
Yoshioka, H1
Kogo, M1
Fujieda, S1
Tanaka, N1
Sunaga, H1
Noda, I1
Sugimoto, C1
Tsuzuki, H1
Saito, H1
Muraki, Y1
Tateishi, A1
Seta, C1
Fukuda, J1
Haneji, T2
Oya, R1
Ikemura, K1
Kobayashi, N1
Okamura, H1
Morimoto, H1
Glaser, CM1
Kornek, GV1
Lang, S1
Schüll, B1
Watzinger, F1
Lavey, RS1
Dobrowsky, W4
Dobrowsky, E3
Strassl, H4
Braun, O3
Gritzmann, N2
Scheiber, V2
Fukazawa, H1
Sekiyama, S1
Yuki, K1
Matsumoto, D1
Takase, K1
Segawa, A1
Takamaru, H1
Braun, OM1
Neumeister, B1
Neuhold, N1
Siebenhandl, A1
Wimmer, M1
Holzner, JH1
Popp, W1
Rausch, EM1

Trials

4 trials available for mitomycin and Mouth Neoplasms

ArticleYear
Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe

2015
[Clinical trial of chemotherapy identified according to chemosensitivity assay for oral cancer patients with unresectable recurrent lesions].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedu

2006
[Clinical and histological effect of induction chemotherapy with peplomycin, vincristine, mitomycin C and cis-platinum on oral squamous cell carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr

1995
Induction chemotherapy is associated with an increase in the incidence of locoregional recurrence in patients with carcinoma of the oral cavity: results from a single institution.
    Cancer, 1998, Mar-01, Volume: 82, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Pr

1998

Other Studies

22 other studies available for mitomycin and Mouth Neoplasms

ArticleYear
SIRT1 inhibits mitochondrial hyperfusion associated mito-bulb formation to sensitize oral cancer cells for apoptosis in a mtROS-dependent signalling pathway.
    Cell death & disease, 2023, 11-10, Volume: 14, Issue:11

    Topics: Apoptosis; Cisplatin; Humans; Mitochondrial Dynamics; Mitomycin; Mouth Neoplasms; Sirtuin 1; Superox

2023
P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC.
    Oral diseases, 2018, Volume: 24, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiothera

2018
Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:3

    Topics: Adult; Carcinoma, Squamous Cell; Chromosome Breakage; DNA Damage; Fanconi Anemia; Female; Genetic Pr

2016
Preoperative radiochemotherapy in the treatment of advanced oral cancer: outcome of 276 patients.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2009, Volume: 37, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cohort Studie

2009
Survival of patients with pathologic T0N+ oral and oropharyngeal cancer after neoadjuvant therapy and surgery: the minority report.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 115, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C

2013
Gastrostomy-site tumor recurrence is not always fatal.
    Surgical endoscopy, 2003, Volume: 17, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brachytherapy; Carcinoma, Squamous Cell; Flu

2003
Quality of life 2-10 years after combined treatment for advanced oral and oropharyngeal cancer.
    International journal of oral and maxillofacial surgery, 2002, Volume: 31, Issue:6

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2002
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:10

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy

2003
Preoperative radiochemotherapy and radical resection for stages II-IV oral and oropharyngeal cancer: outcome of 222 patients.
    International journal of oral and maxillofacial surgery, 2005, Volume: 34, Issue:2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2005
Preoperative radiochemotherapy and radical resection for stages II to IV oral and oropharyngeal cancer: grade of regression as crucial prognostic factor.
    International journal of oral and maxillofacial surgery, 2005, Volume: 34, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fe

2005
Induction chemotherapy with cisplatin, etoposide, and mitomycin-C (PEM) regimen in advanced cases with cancer of pharynx and oral cavity.
    Auris, nasus, larynx, 1995, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy,

1995
[Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:8

    Topics: Carcinoma, Squamous Cell; Cell Division; Dicumarol; DNA Damage; Humans; Leukemia, Myeloid; Mitomycin

1993
[Accelerated hyperfractionated radiotherapy combined with simultaneous chemotherapy in locally advanced pharyngeal and oral carcinomas].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

1994
Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; DNA-Bind

1998
Fas antigen expression and outcome of oral squamous cell carcinoma.
    International journal of oral and maxillofacial surgery, 2000, Volume: 29, Issue:5

    Topics: Actuarial Analysis; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy P

2000
Peplomycin-induced apoptosis in oral squamous carcinoma cells depends on bleomycin sensitivity.
    Oral oncology, 2001, Volume: 37, Issue:4

    Topics: Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Carcinoma, Squamous Cell; Colorimetry; DNA Fragme

2001
Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx.
    International journal of radiation oncology, biology, physics, 2001, Jul-01, Volume: 50, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Erythropoietin; Female; Fl

2001
Combined modality treatment of advanced cancers of the oral cavity and oropharynx.
    International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda

1991
[Clinical studies of B-M therapy in oral cancer with multidisciplinary treatment].
    Nihon Gan Chiryo Gakkai shi, 1986, Feb-20, Volume: 21, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Co

1986
Response to preoperative concomitant radiochemotherapy with mitomycin C and 5-fluorouracil in advanced head and neck cancer.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda

1989
Histological grading of therapy induced regression in squamous cell carcinomas of the oral cavity. A morphological and immunohistochemical study.
    Pathology, research and practice, 1989, Volume: 185, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; H

1989
[Preoperative radiochemotherapy in advanced oral and oropharyngeal carcinoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda

1987