Page last updated: 2024-11-06

mitomycin and Minimal Disease, Residual

mitomycin has been researched along with Minimal Disease, Residual in 28 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Patients with residual tumor on posttreatment biopsy were treated with a salvage regimen that consisted of additional pelvic RT (9 Gy), 5-FU, and cisplatin (100 mg/m2)."2.68Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. ( Coia, L; Doggett, S; Flam, M; John, M; Kerman, H; Murray, K; Myerson, R; Pajak, TF; Petrelli, N; Quivey, J; Rotman, M, 1996)
"The majority of anal cancers are squamous cell carcinomas, and they are treated according to stage."2.52Anal cancer treatment: current status and future perspectives. ( Abdayem, P; Antoun, J; Ghosn, M; Kourie, HR; Nasr, D, 2015)
"Close to 75% of all bladder tumors are confined to the urothelium (stage Ta, or carcinoma in situ), and nearly 30% of papillary tumors invade the lamina propria (stage T1)."2.41Intravesical therapy for superficial bladder cancer. ( Baselli, EC; Greenberg, RE, 2000)
"A pathologic cervical residual tumor was observed in 16 patients (35."1.43[Stage IB2, IIA and IIB cervical carcinoma without lymph node extension treated with neoadjuvant chemoradiotherapy]. ( Ballester, M; Daraï, E; Huguet, F; Lauratet, B; Lefranc, JP; Monnier, L; Touboul, E, 2016)
"Pseudomyxoma peritonei is a diffuse peritoneal malignancy that generally originates form a perforated appendiceal tumor."1.39Complete cytoreduction for pseudomyxoma peritonei is optimal but maximal tumor debulking may be beneficial in patients in whom complete tumor removal cannot be achieved. ( Cecil, TD; Chandrakumaran, K; Dayal, S; Mohamed, F; Moran, BJ; Riss, S; Taflampas, P, 2013)
"We conclude that minimal residual disease, compared with macroscopically complete cytoreduction, correlated to failure in critical anatomical areas, suggesting the need for maximal cytoreductive surgical efforts."1.35Diffuse malignant peritoneal mesothelioma: Failure analysis following cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). ( Baratti, D; Cabras, AD; Deraco, M; Dileo, P; Kusamura, S; Laterza, B, 2009)
"In phase II trials in superficial bladder cancer, marker lesions have been used to test the ablative activity of intravesical chemo- or immunotherapy."1.31Frequency of positive biopsies after visual disappearance of superficial bladder cancer marker lesions. ( Bono, AV; Brausi, M; de Balincourt, C; Hall, R; Mack, D; Oosterlinck, W; Sylvester, R, 2001)
"Mitomycin C was administered initially and mitoxantrone was administered following the same schedule if disease recurred during followup."1.29Up-front intravesical chemotherapy for low stage, low grade recurrent bladder cancer. ( Carmignani, G; Maffezzini, M; Raber, M; Simonato, A; Zanon, M, 1996)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (28.57)18.2507
2000's10 (35.71)29.6817
2010's7 (25.00)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Arjona-Sanchez, A1
Aziz, O1
Passot, G1
Salti, G1
Esquivel, J1
Van der Speeten, K1
Piso, P1
Nedelcut, DS1
Sommariva, A1
Yonemura, Y1
Turaga, K1
Selvasekar, CR1
Rodriguez-Ortiz, L1
Sanchez-Hidalgo, JM1
Casado-Adam, A1
Rufian-Peña, S1
Briceño, J1
Glehen, O1
Barrak, D1
Desale, S1
Yoon, JJ1
Dugan, MM1
Kodavanti, PP1
Sampah, ME1
Sugarbaker, PH2
Zahid, A1
Clarke, L1
Carr, N1
Chandrakumaran, K2
Tzivanakis, A1
Dayal, S2
Mohamed, F2
Cecil, T1
Moran, BJ2
Taflampas, P1
Riss, S1
Cecil, TD1
Ghosn, M1
Kourie, HR1
Abdayem, P1
Antoun, J1
Nasr, D1
Monnier, L1
Touboul, E1
Daraï, E1
Lefranc, JP1
Lauratet, B1
Ballester, M1
Huguet, F1
Ihemelandu, C1
Paiva, B1
Vidriales, MB1
Cerveró, J1
Mateo, G1
Pérez, JJ1
Montalbán, MA1
Sureda, A1
Montejano, L1
Gutiérrez, NC1
García de Coca, A1
de Las Heras, N1
Mateos, MV1
López-Berges, MC1
García-Boyero, R1
Galende, J1
Hernández, J1
Palomera, L1
Carrera, D1
Martínez, R1
de la Rubia, J1
Martín, A1
Bladé, J1
Lahuerta, JJ1
Orfao, A1
San Miguel, JF1
Barlogie, B1
Epstein, J1
Shaughnessy, JD1
Baratti, D1
Kusamura, S1
Cabras, AD1
Dileo, P1
Laterza, B1
Deraco, M1
Kim, K1
Chie, EK1
Jang, JY1
Kim, SW1
Han, SW1
Oh, DY1
Im, SA1
Kim, TY1
Bang, YJ1
Ha, SW1
Roy, P1
Serra, S1
Kennedy, E1
Chetty, R1
Bentzen, AG1
Guren, MG1
Wanderås, EH1
Frykholm, G1
Tveit, KM1
Wilsgaard, T1
Dahl, O1
Balteskard, L1
Klug, C1
Wutzl, A1
Kermer, C1
Ploder, O1
Sulzbacher, I1
Selzer, E1
Voracek, M1
Oeckher, M1
Ewers, R1
Millesi, W1
Mawdsley, S1
Glynne-Jones, R1
Grainger, J1
Richman, P1
Makris, A1
Harrison, M1
Ashford, R1
Harrison, RA1
Osborne, M1
Livingstone, JI1
MacDonald, P1
Mitchell, IC1
Meyrick-Thomas, J1
Northover, JM1
Windsor, A1
Novell, R1
Wallace, M1
Pelz, JO1
Doerfer, J1
Dimmler, A1
Hohenberger, W1
Meyer, T1
Lim, ST1
Jeong, HJ1
Kim, DW1
Yim, CY1
Sohn, MH1
Maffezzini, M1
Simonato, A1
Zanon, M1
Raber, M1
Carmignani, G1
Furukawa, Y1
Otani, Y2
Ihara, A1
Tsuji, R1
Okamura, R1
Sato, K1
Hiki, Y1
Tono, T1
Tamaki, Y1
Yagyu, T1
Mishima, H1
Nakagawa, H1
Cho, G1
Shin, E1
Kobayashi, K1
Takatsuka, Y1
Kikkawa, N1
Takano, S1
Moriguchi, M1
Seki, N1
Higaki, T1
Watanabe, Y2
Takahashi, T1
Ito, Y1
Oishi, H1
Nakata, Y1
Kono, S1
Flam, M1
John, M1
Pajak, TF1
Petrelli, N1
Myerson, R1
Doggett, S1
Quivey, J1
Rotman, M1
Kerman, H1
Coia, L1
Murray, K1
Nabeya, Y1
Okazaki, Y1
Tohnosu, N1
Yamazaki, M1
Matsuda, M1
Iizuka, H1
Akutsu, N1
Kono, T1
Sato, H1
Kubosawa, H1
Takanishi, K1
Matsumoto, J1
Minami, T1
Baselli, EC1
Greenberg, RE1
Oosterlinck, W1
Bono, AV1
Mack, D1
Hall, R1
Sylvester, R1
de Balincourt, C1
Brausi, M1
Frucht-Pery, J1
Rozenman, Y1
Pe'er, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Terry Fox Pan-Canadian Multiple Myeloma Molecular Monitoring Study[NCT03421132]250 participants (Anticipated)Observational2018-02-20Recruiting
Multiple Myeloma 2000. Multicentric Evaluation of a Therapeutic Strategy Optimized in Multiple Myeloma. Analysis of Efficiency and Possible Pronostic Impact of Minimal Residual Disease (Measured By PCR And Citometry of Flow) in Patients With Complete Resp[NCT00560053]Phase 3500 participants (Actual)Interventional2000-01-31Completed
A Perspective, Single Center Study of the MRD-tailored Therapy in Patients With Newly Diagnosed Multiple Myeloma With Persistent Minimal Residual Disease After Initial Treatment[NCT06109233]80 participants (Anticipated)Observational2023-12-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for mitomycin and Minimal Disease, Residual

ArticleYear
Appendiceal tumors with glandular and neuroendocrine features exhibiting peritoneal metastases - Critical evaluation of outcome following cytoreductive surgery with perioperative chemotherapy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:6

    Topics: Adenocarcinoma; Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Proto

2021
Anal cancer treatment: current status and future perspectives.
    World journal of gastroenterology, 2015, Feb-28, Volume: 21, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; C

2015
Intravesical therapy for superficial bladder cancer.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Antibiotics, Antineoplastic; Anticarcinogenic

2000

Trials

5 trials available for mitomycin and Minimal Disease, Residual

ArticleYear
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
[Effect of prophylactic intra-arterial infusion of anticancer drugs on post hepatic resection for hepatic metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administrati

1994
[Evaluation of prophylactic intra-hepatic-arterial infusion chemotherapy after resection of hepatic metastases from colorectal primaries].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Do

1994
[The significance of portal infusion chemotherapy for prevention of recurrence in residual liver after hepatectomy for metastases from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; He

1994
Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

1996

Other Studies

20 other studies available for mitomycin and Minimal Disease, Residual

ArticleYear
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for limited peritoneal metastasis. The PSOGI international collaborative registry.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Cy

2021
Outcomes of multicystic peritoneal mesothelioma treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
    BJS open, 2021, 03-05, Volume: 5, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Cytoreduction Surgical Procedures; Doxorubicin; Femal

2021
Complete cytoreduction for pseudomyxoma peritonei is optimal but maximal tumor debulking may be beneficial in patients in whom complete tumor removal cannot be achieved.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Female; Humans; Hypert

2013
[Stage IB2, IIA and IIB cervical carcinoma without lymph node extension treated with neoadjuvant chemoradiotherapy].
    Bulletin du cancer, 2016, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; C

2016
Management for Peritoneal Metastasis of Colonic Origin: Role of Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy: A Single Institution's Experience During Two Decades.
    Annals of surgical oncology, 2017, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2017
Going with the flow, and beyond, in myeloma.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Dexam

2008
Diffuse malignant peritoneal mesothelioma: Failure analysis following cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC).
    Annals of surgical oncology, 2009, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Combined Mo

2009
Adjuvant chemoradiotherapy after curative resection for extrahepatic bile duct cancer: a long-term single center experience.
    American journal of clinical oncology, 2012, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; B

2012
The prognostic value of grade of regression and oncocytic change in rectal adenocarcinoma treated with neo-adjuvant chemoradiotherapy.
    Journal of surgical oncology, 2012, Volume: 105, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2012
Chemoradiotherapy of anal carcinoma: survival and recurrence in an unselected national cohort.
    International journal of radiation oncology, biology, physics, 2012, Jun-01, Volume: 83, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Ne

2012
Preoperative radiochemotherapy and radical resection for stages II to IV oral and oropharyngeal cancer: grade of regression as crucial prognostic factor.
    International journal of oral and maxillofacial surgery, 2005, Volume: 34, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fe

2005
Can histopathologic assessment of circumferential margin after preoperative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for 3-year disease-free survival?
    International journal of radiation oncology, biology, physics, 2005, Nov-01, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplastic; Combined Moda

2005
Histological response of peritoneal carcinomatosis after hyperthermic intraperitoneal chemoperfusion (HIPEC) in experimental investigations.
    BMC cancer, 2006, Jun-22, Volume: 6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Chemotherapy, Cancer, Regi

2006
F-18 FDG PET-CT findings of intraperitoneal carbon particles-induced granulomas mimicking peritoneal carcinomatosis.
    Clinical nuclear medicine, 2008, Volume: 33, Issue:5

    Topics: Adult; Carbon; Diagnosis, Differential; Extravasation of Diagnostic and Therapeutic Materials; False

2008
Up-front intravesical chemotherapy for low stage, low grade recurrent bladder cancer.
    The Journal of urology, 1996, Volume: 155, Issue:1

    Topics: Administration, Intravesical; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Trans

1996
[Home therapy approach in cancer patients-chemotherapy (case 2-1)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 4

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorourac

1994
Metastatic malignant meningioma of the liver with hypoglycemia: report of a case.
    Surgery today, 1998, Volume: 28, Issue:9

    Topics: Aged; Chemoembolization, Therapeutic; Fatal Outcome; Hepatectomy; Humans; Hypoglycemia; Liver; Liver

1998
[Management after hepatectomy of colorectal cancer metastases to the liver--intrahepatic arterial infusion chemotherapy and repeated hepatectomy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms

1999
Frequency of positive biopsies after visual disappearance of superficial bladder cancer marker lesions.
    European urology, 2001, Volume: 40, Issue:5

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; BCG Vaccine; Biopsy; Carcinoma, Transitio

2001
Topical mitomycin-C for partially excised conjunctival squamous cell carcinoma.
    Ophthalmology, 2002, Volume: 109, Issue:3

    Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Conjunc

2002