Page last updated: 2024-11-06

mitomycin and Middle Ear Effusion

mitomycin has been researched along with Middle Ear Effusion in 7 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"To investigate the use of contact diode laser myringotomy (C-LAM), combined with topical mitomycin C, as an alternative method for prolonged middle ear ventilation in children with otitis media with effusion."5.11Contact diode laser myringotomy and mitomycin C in children. ( D'ereditá, R, 2004)
"To conduct a prospective, randomized, controlled trial determining the feasibility of radiofrequency with or without topical mitomycin C application in delaying the closure time of human tympanostomy and screening its efficacy in management of recurrent acute otitis media and otitis media with effusion."5.11The effect of radiofrequency and mitomycin C on the closure rate of human tympanostomy. ( Ragab, SM, 2005)
"The object of this study was to investigate the efficacy of topical mitomycin C (MMC) in combination with subsequent topical dexamethasone to prolong the patency of myringotomies."1.33Topical application of mitomycin C in combination with dexamethasone: effective delay of myringotomy closure. ( Hosemann, W; Kaftan, H, 2006)
"Mitomycin C has an adjunct effect in laser myringotomy in prolonging the patency rate of myringotomy on rats."1.31Topical use of mitomycin C in laser myringotomy: an experimental study in rats. ( Yucel, OT, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hesham, A1
Hussien, A1
Hussein, A1
D'ereditá, R1
Ragab, SM1
Lachanas, VA2
Prokopakis, EP2
Malandrakis, SG2
Hajiioannou, JK2
Christodoulou, PN2
Velegrakis, GA2
Kaftan, H1
Hosemann, W1
Karatzanis, AD1
Yucel, OT1

Trials

3 trials available for mitomycin and Middle Ear Effusion

ArticleYear
Topical mitomycin C application before myringotomy and ventilation tube insertion: does it affect the final outcome?
    Ear, nose, & throat journal, 2012, Volume: 91, Issue:8

    Topics: Antibiotics, Antineoplastic; Child; Child, Preschool; Female; Humans; Male; Middle Ear Ventilation;

2012
Contact diode laser myringotomy and mitomycin C in children.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2004, Volume: 130, Issue:6

    Topics: Alkylating Agents; Child; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; Hu

2004
The effect of radiofrequency and mitomycin C on the closure rate of human tympanostomy.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2005, Volume: 26, Issue:3

    Topics: Acute Disease; Catheter Ablation; Child; Child, Preschool; Equipment Design; Feasibility Studies; Fe

2005

Other Studies

4 other studies available for mitomycin and Middle Ear Effusion

ArticleYear
Radiofrequency myringotomy with the topical use of mitomycin C: an experimental study.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2006, Volume: 27, Issue:1

    Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Fo

2006
Topical application of mitomycin C in combination with dexamethasone: effective delay of myringotomy closure.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2006, Volume: 68, Issue:4

    Topics: Administration, Topical; Alkylating Agents; Animals; Anti-Inflammatory Agents; Dexamethasone; Drug T

2006
Comparative study of laser versus radiofrequency myringotomy in rabbits: The effectiveness of mitomycin C application.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2006, Volume: 27, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Catheter Ablation; Female; Laser Therapy; Middle Ear Ventilati

2006
Topical use of mitomycin C in laser myringotomy: an experimental study in rats.
    International journal of pediatric otorhinolaryngology, 2000, Aug-31, Volume: 54, Issue:2-3

    Topics: Administration, Topical; Animals; Combined Modality Therapy; Disease Models, Animal; Laser Therapy;

2000