mitomycin has been researched along with Microsatellite Instability in 4 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Microsatellite Instability: The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with metastatic colorectal cancer (mCRC) carrying BRAF (mutBRAF) or KRAS mutation (mutKRAS) have an inferior prognosis after liver or lung surgery, whereas the prognostic role in the context of peritoneal metastasis (PM) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been less investigated." | 1.72 | Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients. ( Dagenborg, VJ; Dueland, S; Flatmark, K; Goscinski, MA; Hofsli, E; Larsen, SG; Lund-Iversen, M; Sorbye, H; Steigen, SE; Torgunrud, A, 2022) |
| "The expanded CAG repeat in the Huntington's disease (HD) gene may display tissue-specific variability (e." | 1.35 | DNA instability in replicating Huntington's disease lymphoblasts. ( Cannella, M; Frati, L; Li, GM; Maglione, V; Martino, T; Ragona, G; Squitieri, F, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larsen, SG | 1 |
| Goscinski, MA | 1 |
| Dueland, S | 1 |
| Steigen, SE | 1 |
| Hofsli, E | 1 |
| Torgunrud, A | 1 |
| Lund-Iversen, M | 1 |
| Dagenborg, VJ | 1 |
| Flatmark, K | 1 |
| Sorbye, H | 1 |
| Matsuzaki, K | 1 |
| Borel, V | 1 |
| Adelman, CA | 1 |
| Schindler, D | 1 |
| Boulton, SJ | 1 |
| Massalou, D | 1 |
| Benizri, E | 1 |
| Chevallier, A | 1 |
| Duranton-Tanneur, V | 1 |
| Pedeutour, F | 1 |
| Benchimol, D | 1 |
| Béréder, JM | 1 |
| Cannella, M | 1 |
| Maglione, V | 1 |
| Martino, T | 1 |
| Ragona, G | 1 |
| Frati, L | 1 |
| Li, GM | 1 |
| Squitieri, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnostic Value of Diffusion-weighted Magnetic Resonance Imaging for Detection of Peritoneal Recurrence in Patients With High-risk Colorectal and Appendiceal Neoplasms : a Pilot Study[NCT05623787] | 30 participants (Anticipated) | Interventional | 2022-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for mitomycin and Microsatellite Instability
| Article | Year |
|---|---|
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients.
Topics: Adult; Colorectal Neoplasms; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermic Intrape | 2022 |
FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway.
Topics: Animals; Antineoplastic Agents; Basic-Leucine Zipper Transcription Factors; Camptothecin; Cell Line; | 2015 |
Peritoneal carcinomatosis of colorectal cancer: novel clinical and molecular outcomes.
Topics: Adenocarcinoma; Adult; Aged; Body Mass Index; Chemotherapy, Cancer, Regional Perfusion; Colonic Neop | 2017 |
DNA instability in replicating Huntington's disease lymphoblasts.
Topics: Cell Division; Cell Line; Cross-Linking Reagents; Ethidium; Ethyl Methanesulfonate; Female; Humans; | 2009 |