Page last updated: 2024-11-06

mitomycin and Mesothelioma

mitomycin has been researched along with Mesothelioma in 49 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)."9.12Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006)
"Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy."9.11The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004)
"Between October 1986 and June 1997, 39 patients with advanced inoperable malignant mesothelioma were treated with palliative MVP (mitomycin-C 8 mg/m2 q."9.08Good symptom relief with palliative MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in malignant mesothelioma. ( Ashley, S; Hickish, T; Middleton, GW; Norton, A; O'Brien, ME; Priest, K; Smith, IE; Spencer, L, 1998)
"Twelve patients with malignant pleural mesothelioma were subjected to mitomycin C (MMC) and vindesine (VDS) chemotherapy (MMC 10 mg/m2, i."7.68Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma. ( Airoma, G; Bianco, AR; Gridelli, C; Incoronato, P; Palazzolo, G; Pepe, R; Rossi, A, 1992)
" Twenty-one patients with PC (12 gastric cancer, 5 colorectal cancer, 2 ovarian cancer, 1 pseudomyxoma peritonei, 1 malignant mesothelioma) were treated with CRS + HIPEC with hydroxycamptothecin 20 mg and mitomycin C 30 mg in 12,000 mL of normal saline at 43 +/- ."5.14Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases. ( al-shammaa Hassan, AH; Li, Y; Liu, SY; Lu, YL; Yang, GL; Yang, XJ; Yonemura, Y; Zhang, JW, 2009)
"We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)."5.12Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006)
"Between October 1986 and May 2002 all patients with inoperable pleural mesothelioma were considered for treatment with MVP (mitomycin C 8 mg/m2 every 6 weeks, vinblastine 6 mg/m2 every 3 weeks and cisplatin 50 mg/m2 every 3 weeks) chemotherapy."5.11The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. ( Andreopoulou, E; Ashley, S; Eisen, T; Ford, HE; Norton, A; O'Brien, ME; Priest, K; Ross, PJ; Smith, IE, 2004)
"The objectives of this study were to determine the toxicity of intratumoural/intrapleural SRL172 in addition to intradermal SRL172 and standard chemotherapy (mitomycin-C, vinblastine and cisplatin) in patients with malignant mesothelioma."5.10Clinical and immunological assessment of Mycobacterium vaccae (SRL172) with chemotherapy in patients with malignant mesothelioma. ( Ashley, S; Bromelow, KV; Gregory, RK; Mendes, R; Mitra, A; Norton, A; O'Brien, ME; Padhani, AR; Smith, IE; Souberbielle, BE; Winkley, AR, 2002)
"Between October 1986 and June 1997, 39 patients with advanced inoperable malignant mesothelioma were treated with palliative MVP (mitomycin-C 8 mg/m2 q."5.08Good symptom relief with palliative MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in malignant mesothelioma. ( Ashley, S; Hickish, T; Middleton, GW; Norton, A; O'Brien, ME; Priest, K; Smith, IE; Spencer, L, 1998)
" More than 50% of centers administer oxaliplatin (74%), or mitomycin-C (65%) in colorectal cancer; cisplatin in gastric cancer (73%) and mesothelioma (74%)."3.88Current practice in cytoreductive surgery and HIPEC for metastatic peritoneal disease: Spanish multicentric survey. ( Barrios, P; Cascales-Campos, P; Esteve-Pérez, N; Morales-Soriano, R; Segura-Sampedro, JJ, 2018)
"Twelve patients with malignant pleural mesothelioma were subjected to mitomycin C (MMC) and vindesine (VDS) chemotherapy (MMC 10 mg/m2, i."3.68Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma. ( Airoma, G; Bianco, AR; Gridelli, C; Incoronato, P; Palazzolo, G; Pepe, R; Rossi, A, 1992)
"To evaluate the tolerance of peritonectomy procedures (PP) combined with intraperitoneal chemohyperthermia (IPCH) in patients with peritoneal carcinomatosis (PC), a phase II study was carried out from January 1998 to September 2001."2.71Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study. ( Beaujard, AC; Francois, Y; Freyer, G; Gilly, FN; Glehen, O; Guertsch, P; Mithieux, F; Osinsky, D; Panteix, G; Peyrat, P; Vignal, J, 2003)
"Malignant pleural mesothelioma is associated with a poor prognosis because of its resistance to treatment."2.69Results of a phase II trial of combined chemotherapy for patients with diffuse malignant mesothelioma of the pleura. ( Astoul, P; Boutin, C; Kasseyet, S, 1999)
" 28 evaluable patients with previously untreated symptomatic NSCLC and mesothelioma were randomized to receive either 3 weekly intravenous combination chemotherapy alone, or chemotherapy given with monthly intra-dermal injections of SRL172."2.69A randomized phase II study of SRL172 (Mycobacterium vaccae) combined with chemotherapy in patients with advanced inoperable non-small-cell lung cancer and mesothelioma. ( Bromelow, KV; Gregory, K; Kennard, DA; Mendes, R; O'Brien, ME; Palmer, RD; Priest, K; Ryan, C; Saini, A; Smith, IE; Souberbielle, BE; Tuckwell, N; Webb, A, 2000)
"Bibasilar atelectasis and pleural effusions are common findings after IPHC with MMC, but most of them do not necessarily warrant intervention."2.68Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery. ( Chen, MY; Chiles, C; Choplin, RH; Fleming, RA; Loggie, BW; Perini, MA, 1997)
"Patients with PC from colorectal or appendiceal cancer, pseudomyxoma peritonei or malignant peritoneal mesothelioma referred to the single national HIPEC centre were prospectively registered from June 2006 to July 2012."1.39Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: the Danish experience. ( Hagemann-Madsen, R; Iversen, LH; Laurberg, S; Rasmussen, PC, 2013)
"Mean time to disease progression was 2."1.39Nonselective transarterial chemoperfusion: a palliative treatment for malignant pleural mesothelioma. ( Gurung, J; Lindemayr, S; Mbalisike, EC; Naguib, NN; Nour-Eldin, NE; Vogl, TJ; Zangos, S, 2013)
"We conclude that minimal residual disease, compared with macroscopically complete cytoreduction, correlated to failure in critical anatomical areas, suggesting the need for maximal cytoreductive surgical efforts."1.35Diffuse malignant peritoneal mesothelioma: Failure analysis following cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). ( Baratti, D; Cabras, AD; Deraco, M; Dileo, P; Kusamura, S; Laterza, B, 2009)
"Peritoneal mesothelioma is a rare disease with few therapeutic options."1.33Peritoneal mesothelioma treated by cytoreductive surgery and intraperitoneal hyperthermic chemotherapy: results of a prospective study. ( Brigand, C; Gilly, FN; Glehen, O; Isaac, S; Mohamed, F; Monneuse, O; Sayag-Beaujard, AC, 2006)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.16)18.7374
1990's8 (16.33)18.2507
2000's20 (40.82)29.6817
2010's13 (26.53)24.3611
2020's4 (8.16)2.80

Authors

AuthorsStudies
Baron, C1
Buchholz, M1
Majchrzak-Stiller, B1
Peters, I1
Fein, D1
Müller, T1
Uhl, W1
Höhn, P1
Strotmann, J1
Braumann, C1
Forsythe, SD1
Erali, RA1
Edenhoffer, N1
Meeker, W1
Wajih, N1
Schaaf, CR1
Laney, P1
Vanezuela, CD1
Li, W1
Levine, EA2
Soker, S1
Votanopoulos, KI1
Arjona-Sanchez, A1
Aziz, O1
Passot, G3
Salti, G2
Esquivel, J1
Van der Speeten, K1
Piso, P1
Nedelcut, DS1
Sommariva, A1
Yonemura, Y2
Turaga, K1
Selvasekar, CR1
Rodriguez-Ortiz, L1
Sanchez-Hidalgo, JM1
Casado-Adam, A1
Rufian-Peña, S1
Briceño, J1
Glehen, O4
Zahid, A1
Clarke, L1
Carr, N1
Chandrakumaran, K2
Tzivanakis, A1
Dayal, S1
Mohamed, F3
Cecil, T2
Moran, BJ1
Morales-Soriano, R1
Esteve-Pérez, N1
Segura-Sampedro, JJ1
Cascales-Campos, P1
Barrios, P1
Malgras, B1
Gayat, E1
Aoun, O1
Lo Dico, R1
Eveno, C1
Pautrat, K1
Delhorme, JB1
Marchal, F1
Sgarbura, O1
Ferron, G1
Goéré, D1
Andre, T1
Pocard, M1
Iversen, LH1
Rasmussen, PC1
Hagemann-Madsen, R1
Laurberg, S1
Baratti, D4
Kusamura, S5
Cabras, AD2
Bertulli, R2
Hutanu, I1
Deraco, M5
Magge, D1
Zenati, MS1
Austin, F1
Mavanur, A1
Sathaiah, M1
Ramalingam, L1
Jones, H1
Zureikat, AH1
Holtzman, M1
Ahrendt, S1
Pingpank, J1
Zeh, HJ1
Bartlett, DL1
Choudry, HA1
Bakrin, N1
Roux, AS1
Vaudoyer, D1
Gilly, FN3
Cotte, E1
Shetty, SJ1
Bathla, L1
Govindarajan, V1
Thomas, P1
Loggie, BW2
Bhagwandin, S1
Naffouje, S1
Moran, B1
Arnold, S1
Venkatasubramaniam, A1
Huang, Y1
Alzahrani, NA1
Liauw, W1
Morris, DL1
Yang, XJ1
Li, Y1
al-shammaa Hassan, AH1
Yang, GL1
Liu, SY1
Lu, YL1
Zhang, JW1
Dileo, P1
Laterza, B1
Blackham, AU1
Shen, P1
Stewart, JH1
Russell, GB1
Rueth, NM1
Murray, SE1
Huddleston, SJ1
Abbott, AM1
Greeno, EW1
Kirstein, MN1
Tuttle, TM1
Vogl, TJ1
Lindemayr, S1
Naguib, NN1
Gurung, J1
Nour-Eldin, NE1
Zangos, S1
Mbalisike, EC1
Ruffié, P2
Mithieux, F1
Osinsky, D1
Beaujard, AC1
Freyer, G1
Guertsch, P1
Francois, Y1
Peyrat, P1
Panteix, G1
Vignal, J1
Casali, P2
Inglese, MG1
Pennacchioli, E1
Andreopoulou, E1
Ross, PJ1
O'Brien, ME4
Ford, HE1
Priest, K3
Eisen, T1
Norton, A3
Ashley, S3
Smith, IE4
Fennell, DA2
Parmar, A1
Shamash, J2
Evans, MT2
Sheaff, MT2
Sylvester, R1
Dhaliwal, K1
Gower, N1
Steele, J1
Rudd, R1
Sugarbaker, PH2
Nonaka, D1
Rosai, J1
Younan, R1
Salvatore, A1
Cabras Ad, AD1
Brigand, C1
Monneuse, O1
Sayag-Beaujard, AC1
Isaac, S1
Pinto, C2
Marino, A2
De Pangher Manzini, V1
Benedetti, G1
Galetta, D1
Mazzanti, P1
Del Conte, G1
dell'Amore, D1
Piana, E2
Giaquinta, S1
Lopez, M1
Martoni, A2
Yan, TD1
Stuart, OA1
Yoo, D1
De Simone, M1
Rossi, CR1
Cavaliere, F1
Difilippo, F1
Scuderi, S1
Pilatti, P1
Steele, JP1
Wells, P1
Rudd, RM1
Stebbing, J1
Hesdorffer, ME1
Chabot, JA1
Keohan, ML1
Fountain, K1
Talbot, S1
Gabay, M1
Valentin, C1
Lee, SM1
Taub, RN1
Chahinian, AP2
Norton, L1
Holland, JF2
Szrajer, L2
Hart, RD1
Rice, TW1
Adelstein, DJ1
Kirby, TJ1
Saltarelli, MG1
Murthy, SR1
Van Kirk, MA1
Wiedemann, HP1
Weick, JK1
Sauter, ER1
Langer, C1
Coia, LR1
Goldberg, M1
Keller, SM1
Hastürk, S1
Tastepe, I1
Unlü, M1
Cetin, G1
Baris, YI1
Chen, MY1
Chiles, C1
Choplin, RH1
Perini, MA1
Fleming, RA1
Middleton, GW1
Hickish, T1
Spencer, L1
Kasseyet, S1
Astoul, P1
Boutin, C1
Fizazi, K1
Caliandro, R1
Soulié, P1
Fandi, A1
Daniel, C1
Bedin, A1
Doubre, H1
Viala, J1
Rodier, J1
Trandafir, L1
Le Chevalier, T1
Cvitkovic, E1
Armand, J1
Saini, A1
Webb, A1
Gregory, K1
Mendes, R2
Ryan, C1
Bromelow, KV2
Palmer, RD1
Tuckwell, N1
Kennard, DA1
Souberbielle, BE2
Guaraldi, M1
Melotti, B1
Pannuti, F1
Mitra, A1
Gregory, RK1
Padhani, AR1
Winkley, AR1
Riviere, A1
Gridelli, C1
Pepe, R1
Airoma, G1
Incoronato, P1
Rossi, A1
Palazzolo, G1
Bianco, AR1
Umsawasdi, T1
Dhingra, HM1
Charnsangavej, C1
Luna, MA1
Sklarin, NT1
Feuer, EJ1
Lahman, LA1
Hayashi, T1
Nasu, Y1
Aramaki, K1
Johsen, T1
Matsuura, H1
Asakura, S1
Matsui, T1
Tatsumi, A1
Fujio, A1
Kitano, M1
Kobashi, Y1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Multicenter Randomized Trial Evaluating the Association of PIPAC and Systemic Chemotherapy Versus Systemic Chemotherapy Alone as 1st-line Treatment of Malignant Peritoneal Mesothelioma[NCT03875144]Phase 266 participants (Anticipated)Interventional2020-08-14Recruiting
Cytoreductive Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy for the Treatment of Peritoneal Carcinomatosis From Gastrointestinal Cancer: an Open Label, Randomized, Prospective, Phase 2 Clinical Trial[NCT00454519]Phase 260 participants (Anticipated)Interventional2007-03-31Recruiting
A Phase III Randomized Study Evaluating Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in the Treatment of Relapse Ovarian Cancer[NCT01376752]Phase 3415 participants (Actual)Interventional2011-04-26Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for mitomycin and Mesothelioma

ArticleYear
Comprehensive management of diffuse malignant peritoneal mesothelioma.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2006, Volume: 32, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubicin; H

2006
Combination raltitrexed (Tomudex(R))-oxaliplatin: a step forward in the struggle against mesothelioma? The Institut Gustave Roussy experience with chemotherapy and chemo-immunotherapy in mesothelioma.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase I as

2000
[Does treatment for malignant pleural mesothelioma exist?].
    Revue de pneumologie clinique, 2001, Volume: 57, Issue:5 Pt 2

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineopl

2001

Trials

18 trials available for mitomycin and Mesothelioma

ArticleYear
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases.
    Annals of surgical oncology, 2009, Volume: 16, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma

2009
Severe electrolyte disturbances after hyperthermic intraperitoneal chemotherapy: oxaliplatin versus mitomycin C.
    Annals of surgical oncology, 2011, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clin

2011
Surgery combined with peritonectomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-01, Volume: 21, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2003
Peritoneal mesothelioma treated by induction chemotherapy, cytoreductive surgery, and intraperitoneal hyperthermic perfusion.
    Journal of surgical oncology, 2003, Volume: 83, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D

2003
The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:9

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin;

2004
Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion.
    Annals of surgical oncology, 2006, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Cancer, Regio

2006
Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1).
    Lung cancer (Amsterdam, Netherlands), 2006, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Therapy,

2006
An Italian Multicentric Phase II study on peritonectomy and intra peritoneal hyperthermic perfusion (IPHP) to treat patients with peritoneal mesothelioma.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:4 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio

2003
Combined resection, intraperitoneal chemotherapy, and whole abdominal radiation for the treatment of malignant peritoneal mesothelioma.
    American journal of clinical oncology, 2008, Volume: 31, Issue:1

    Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adju

2008
Experimental and clinical activity of mitomycin C and cis-diamminedichloroplatinum in malignant mesothelioma.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Aged; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Lin

1984
Optimal management of malignant mesothelioma after subtotal pleurectomy: revisiting the role of intrapleural chemotherapy and postoperative radiation.
    Journal of surgical oncology, 1995, Volume: 60, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cytarabi

1995
Combined chemotherapy in pleurectomized malignant pleural mesothelioma patients.
    Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin;

1996
Thoracic complications in patients undergoing intraperitoneal heated chemotherapy with mitomycin following cytoreductive surgery.
    Journal of surgical oncology, 1997, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Female; Gastrointes

1997
Good symptom relief with palliative MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in malignant mesothelioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:3

    Topics: Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Human

1998
Results of a phase II trial of combined chemotherapy for patients with diffuse malignant mesothelioma of the pleura.
    Cancer, 1999, Apr-15, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asbestos; Cisplatin; Combined Modality

1999
A randomized phase II study of SRL172 (Mycobacterium vaccae) combined with chemotherapy in patients with advanced inoperable non-small-cell lung cancer and mesothelioma.
    British journal of cancer, 2000, Volume: 83, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vacci

2000
Combination chemotherapy with mitoxantrone, methotrexate, and mitomycin (MMM regimen) in malignant pleural mesothelioma: a phase II study.
    American journal of clinical oncology, 2001, Volume: 24, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Mesothelioma; Methotrexa

2001
Clinical and immunological assessment of Mycobacterium vaccae (SRL172) with chemotherapy in patients with malignant mesothelioma.
    British journal of cancer, 2002, Feb-01, Volume: 86, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Cisplatin; Disease-Free Su

2002

Other Studies

28 other studies available for mitomycin and Mesothelioma

ArticleYear
Substance GP-2250 as a New Therapeutic Agent for Malignant Peritoneal Mesothelioma-A 3-D In Vitro Study.
    International journal of molecular sciences, 2022, Jun-30, Volume: 23, Issue:13

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin;

2022
Cisplatin exhibits superiority over MMC as a perfusion agent in a peritoneal mesothelioma patient specific organoid HIPEC platform.
    Scientific reports, 2023, 07-19, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Humans; Hypert

2023
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for limited peritoneal metastasis. The PSOGI international collaborative registry.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021, Volume: 47, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Cy

2021
Outcomes of multicystic peritoneal mesothelioma treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
    BJS open, 2021, 03-05, Volume: 5, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Cytoreduction Surgical Procedures; Doxorubicin; Femal

2021
Current practice in cytoreductive surgery and HIPEC for metastatic peritoneal disease: Spanish multicentric survey.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2018, Volume: 44, Issue:2

    Topics: Antineoplastic Agents; Carcinoma; Cardiac Output; Cisplatin; Colorectal Neoplasms; Cytoreduction Sur

2018
Impact of Combination Chemotherapy in Peritoneal Mesothelioma Hyperthermic Intraperitoneal Chemotherapy (HIPEC): The RENAPE Study.
    Annals of surgical oncology, 2018, Volume: 25, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin;

2018
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: the Danish experience.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Appendiceal Neoplasms; Carcinoma; Colorectal Neoplasms; Co

2013
Diffuse malignant peritoneal mesothelioma: long-term survival with complete cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC).
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D

2013
Malignant peritoneal mesothelioma: prognostic factors and oncologic outcome analysis.
    Annals of surgical oncology, 2014, Volume: 21, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin;

2014
Quality of life after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy: a prospective study of 216 patients.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2014, Volume: 40, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Cisplatin; Cohort Stu

2014
Comparison of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy with mitomycin or carboplatin for diffuse malignant peritoneal mesothelioma.
    The American surgeon, 2014, Volume: 80, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carboplatin; Combined Modality Therapy; Female;

2014
Utility of Chemoresponse Assay in Patients Undergoing Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy.
    Annals of surgical oncology, 2015, Volume: 22, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytoreductio

2015
The results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in 1200 patients with peritoneal malignancy.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2015, Volume: 17, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Colorectal Neoplas

2015
Repeat cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent diffuse malignant peritoneal mesothelioma.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Cisplatin; Cohort Studies; C

2015
Diffuse malignant peritoneal mesothelioma: Failure analysis following cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC).
    Annals of surgical oncology, 2009, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Combined Mo

2009
Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for malignant peritoneal mesothelioma: mitomycin versus cisplatin.
    Annals of surgical oncology, 2010, Volume: 17, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio

2010
Nonselective transarterial chemoperfusion: a palliative treatment for malignant pleural mesothelioma.
    Radiology, 2013, Volume: 266, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Disease Progression; Femal

2013
[New therapeutic options for mesothelioma].
    Revue de pneumologie clinique, 2002, Volume: 58, Issue:5 Pt 2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Ant

2002
Statistical validation of the EORTC prognostic model for malignant pleural mesothelioma based on three consecutive phase II trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jan-01, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemo

2005
An instrument to provide containment of intraoperative intraperitoneal chemotherapy with optimized distribution.
    Journal of surgical oncology, 2005, Nov-01, Volume: 92, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Containment of Bio

2005
Peritoneal mesothelioma treated by cytoreductive surgery and intraperitoneal hyperthermic chemotherapy: results of a prospective study.
    Annals of surgical oncology, 2006, Volume: 13, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; F

2006
Efficacy and safety of first- or second-line irinotecan, cisplatin, and mitomycin in mesothelioma.
    Cancer, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Clinical Trial

2007
Aggressive multimodality therapy for malignant pleural mesothelioma.
    The Annals of thoracic surgery, 1994, Volume: 58, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Feasibility St

1994
Mitomycin C and vindesine: an ineffective combination chemotherapy in the treatment of malignant pleural mesothelioma.
    Tumori, 1992, Dec-31, Volume: 78, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; H

1992
A case report of malignant pleural mesothelioma with long-term disease control after chemotherapy.
    Cancer, 1991, Jan-01, Volume: 67, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide;

1991
Augmentation of activity of cis-diamminedichloroplatinum(II) and mitomycin C by interferon in human malignant mesothelioma xenografts in nude mice.
    Cancer research, 1988, Jan-01, Volume: 48, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Synergism; Female; Humans;

1988
[A case of peritoneal malignant mesothelioma with disappearance of ascites result of intraperitoneal instillation of mitomycin C and oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cryptorch

1989
[A case of malignant pleural mesothelioma and its sensitivity tests for anti-cancer drugs].
    Nihon Kyobu Shikkan Gakkai zasshi, 1988, Volume: 26, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug

1988