mitomycin has been researched along with Melanoma in 92 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Local chemotherapy with mitomycin C is a useful option in the treatment of malignant melanomas of the conjunctiva associated with PAM if the tumor stage is pT3 or less." | 9.10 | [Management of conjunctival malignant melanoma associated with primary acquired melanosis (PAM) using 0.02% mitomycin C eyedrops]. ( Conway, RM; Groh, MJ; Holbach, LM; Kühnel, B; Naumann, GO, 2003) |
| "To clinically evaluate topical mitomycin chemotherapy in patients with diffuse, multifocal, or recurrent primary acquired melanosis with atypia and/or conjunctival malignant melanoma and to histopathologically study ocular tissue samples obtained before and after treatment." | 9.09 | Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations. ( Demirci, H; Finger, PT; McCormick, SA, 2000) |
| "To evaluate topical mitomycin C (MMC) chemotherapy in the treatment of conjunctival melanoma and primary acquired melanosis with atypia." | 9.08 | Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia. ( Czechonska, G; Finger, PT; Liarikos, S, 1998) |
| "To report a case of a large conjunctival melanoma (CM) successfully treated with surgical resection and pre- and postoperative topical mitomycin C (MMC)." | 8.02 | Extensive conjunctival melanoma successfully treated with surgical resection and pre- and postoperative topical mitomycin C. ( Giansanti, F; Mazzini, C; Nicolosi, C; Pieretti, G; Vicini, G; Virgili, G, 2021) |
| "To describe the clinical and histological resolution of a case of an inexcisable conjunctival melanoma using topical interferon alpha 2b (INFα2b) in a patient with mitomycin C (MMC) intolerance." | 7.88 | Resolution of conjunctival melanoma with topical interferon alpha 2b in a patient with mitomycin C intolerance. ( Chaparro Tapias, TA; Coy Villamil, H; Díaz Díaz, AL; Sánchez España, JC; Secondi, R, 2018) |
| "To report the long-term complications and rate of local recurrence in a cohort of patients with histopathologically confirmed conjunctival melanoma (CM) treated with adjuvant topical mitomycin C (MMC)." | 7.77 | Outcomes in 15 patients with conjunctival melanoma treated with adjuvant topical mitomycin C: complications and recurrences. ( Ditta, LC; Shildkrot, Y; Wilson, MW, 2011) |
| "To investigate the effects of mitomycin C and the histone deacetylase inhibitors sodium butyrate and trichostatin on the viability and growth of conjunctival melanoma cell lines and Tenon capsule fibroblasts." | 7.75 | In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. ( Conway, RM; Cunneen, TS; Madigan, MC, 2009) |
| " Mitomycin was a primary treatment for residual epithelial disease in ten patients (eight with PAM with atypia and two with conjunctival melanoma) and as an adjuvant to excision and cryotherapy in six with conjunctival malignant melanoma." | 7.73 | Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: 12 years' experience. ( Finger, PT; Kurli, M, 2005) |
| "To present the clinical and histologic findings of a patient in whom intumescent cataract developed after successful topical mitomycin-C (MMC) chemotherapy for conjunctival melanoma originating from primary acquired conjunctival melanosis (PAM) with atypia." | 7.72 | Intumescent cataract after topical mitomycin-C for conjunctival malignant melanoma. ( Horvat, R; Lukas, JR; Sacu, S; Ségur-Eltz, N; Zehetmayer, M, 2003) |
| "Since 1995 we have used Mitomycin C additionally in the treatment of conjunctival melanoma and primary acquired melanosis." | 7.70 | [Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis]. ( Lommatzsch, PK; Werschnik, C, 1998) |
| "Baseline and mitomycin C (MMC)-induced sister chromatid exchanges (SCEs) in two human tumor cell lines (a colon tumor and a melanoma) and in a normal fibroblast cell line were analyzed and compared." | 7.66 | Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line. ( Au, WW; Hsu, TC; Li, S; Schmoyer, RL, 1982) |
| "The response rate and time to disease progression were the primary endpoints, with overall survival as the secondary endpoint." | 6.71 | Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study. ( Amicucci, G; Deraco, M; Di Filippo, F; Fiorentini, G; Guadagni, S; Miotto, D; Patuzzo, R; Pilati, PL; Rossi, CR; Santinami, M; Valenti, M, 2003) |
| " If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications." | 5.31 | [The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001) |
| "We observed euploid DNA-polyploidy and cytomorphological changes in all patients (19/19)." | 5.31 | Topical mitomycin C and radiation induce conjunctival DNA-polyploidy. ( Böcking, A; Cartsburg, O; Hillenkamp, J; Kallen, C; Pomjanski, N; Sundmacher, R, 2001) |
| "Local chemotherapy with mitomycin C is a useful option in the treatment of malignant melanomas of the conjunctiva associated with PAM if the tumor stage is pT3 or less." | 5.10 | [Management of conjunctival malignant melanoma associated with primary acquired melanosis (PAM) using 0.02% mitomycin C eyedrops]. ( Conway, RM; Groh, MJ; Holbach, LM; Kühnel, B; Naumann, GO, 2003) |
| "To clinically evaluate topical mitomycin chemotherapy in patients with diffuse, multifocal, or recurrent primary acquired melanosis with atypia and/or conjunctival malignant melanoma and to histopathologically study ocular tissue samples obtained before and after treatment." | 5.09 | Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations. ( Demirci, H; Finger, PT; McCormick, SA, 2000) |
| "To evaluate topical mitomycin C (MMC) chemotherapy in the treatment of conjunctival melanoma and primary acquired melanosis with atypia." | 5.08 | Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia. ( Czechonska, G; Finger, PT; Liarikos, S, 1998) |
| " One patient with aggressive fibromatosis was treated with TNF alone (200 micrograms/m2, days 1-5 every third week) and 10 patients (four colon cancer, four head and neck cancer; one melanoma; one sarcoma) received mitomycin C (15 mg/m2, day 1) followed by TNF (60-180 micrograms/m2, days 1-3) every sixth week." | 5.08 | Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients. ( Gooding, W; Kirkwood, JM; Logan, TF; Shadduck, RK, 1996) |
| "To report a case of a large conjunctival melanoma (CM) successfully treated with surgical resection and pre- and postoperative topical mitomycin C (MMC)." | 4.02 | Extensive conjunctival melanoma successfully treated with surgical resection and pre- and postoperative topical mitomycin C. ( Giansanti, F; Mazzini, C; Nicolosi, C; Pieretti, G; Vicini, G; Virgili, G, 2021) |
| "To describe the clinical and histological resolution of a case of an inexcisable conjunctival melanoma using topical interferon alpha 2b (INFα2b) in a patient with mitomycin C (MMC) intolerance." | 3.88 | Resolution of conjunctival melanoma with topical interferon alpha 2b in a patient with mitomycin C intolerance. ( Chaparro Tapias, TA; Coy Villamil, H; Díaz Díaz, AL; Sánchez España, JC; Secondi, R, 2018) |
| "The recommended treatment for conjunctival melanoma is surgical removal with adjunctive therapies such as cryotherapy or topical mitomycin-C." | 3.80 | [Treatment of conjunctival melanoma]. ( Baamonde Arbaiza, B; de la Roz Martín, P; Parra Rodríguez, T; Salazar Méndez, R, 2014) |
| "To report the long-term complications and rate of local recurrence in a cohort of patients with histopathologically confirmed conjunctival melanoma (CM) treated with adjuvant topical mitomycin C (MMC)." | 3.77 | Outcomes in 15 patients with conjunctival melanoma treated with adjuvant topical mitomycin C: complications and recurrences. ( Ditta, LC; Shildkrot, Y; Wilson, MW, 2011) |
| "Persistent epitheliopathy, presumably resulting from limbal stem cell deficiency, is an uncommon complication of treatment of conjunctival malignant melanoma with surgical excision, cryotherapy, and mitomycin C." | 3.76 | Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma. ( Colby, KA; Grover, S; Jacobs, DS, 2010) |
| "To investigate the effects of mitomycin C and the histone deacetylase inhibitors sodium butyrate and trichostatin on the viability and growth of conjunctival melanoma cell lines and Tenon capsule fibroblasts." | 3.75 | In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. ( Conway, RM; Cunneen, TS; Madigan, MC, 2009) |
| " We compare and contrast the histopathology of a normally functioning mitomycin-C trabeculectomy site obtained from an eye enucleated for iris melanoma with abnormal blebs discussed in the literature." | 3.75 | Histopathology of a functioning mitomycin-C trabeculectomy. ( Lee, GA; Liang, SY; Whitehead, K, 2009) |
| " Mitomycin was a primary treatment for residual epithelial disease in ten patients (eight with PAM with atypia and two with conjunctival melanoma) and as an adjuvant to excision and cryotherapy in six with conjunctival malignant melanoma." | 3.73 | Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: 12 years' experience. ( Finger, PT; Kurli, M, 2005) |
| "To present the clinical and histologic findings of a patient in whom intumescent cataract developed after successful topical mitomycin-C (MMC) chemotherapy for conjunctival melanoma originating from primary acquired conjunctival melanosis (PAM) with atypia." | 3.72 | Intumescent cataract after topical mitomycin-C for conjunctival malignant melanoma. ( Horvat, R; Lukas, JR; Sacu, S; Ségur-Eltz, N; Zehetmayer, M, 2003) |
| " Nitrotriazole chemosensitizer in ultralow doses increased the sensitivity of leukemia P388/rn substrain with multiple drug resistance phenotype to mitomycin C during combination therapy." | 3.72 | Ultralow doses of various drugs in chemotherapy of experimental tumors. ( Konovalova, NP, 2003) |
| "Since 1995 we have used Mitomycin C additionally in the treatment of conjunctival melanoma and primary acquired melanosis." | 3.70 | [Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis]. ( Lommatzsch, PK; Werschnik, C, 1998) |
| "Cytotoxic T lymphocytes (CTL) against autologous malignant brain tumor were generated in peripheral blood lymphoid cells (PBL) prepared from a patient with a malignant brain tumor by stimulation of the cultured PBL for 7 days with attenuated crossreactive malignant melanoma (MM2) cells pretreated with mitomycin C." | 3.69 | Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation. ( Fujimoto, S; Kurisaka, M; Maeda, N; Mori, K; Saitoh, S, 1997) |
| "The three-dimensional growth of cultured tumor cell lines (HT29, a colon adenocarcinoma cell line; M21, a melanoma cell line; KB, a nasopharyngeal carcinoma cell line) has been investigated in an agar culture system with a fibrin matrix in vitro." | 3.68 | Morphologic analysis of three-dimensional tumors developed in fibrin matrix and agar culture system. ( Hess, M; Koldovsky, P; Kumazawa, H, 1993) |
| " Results of treatment of B16 melanoma and Lewis lung carcinoma with 3,4-dihydroxybenzohydroxamic acid are used to demonstrate this definition." | 3.66 | Drug activity and therapeutic synergism in cancer treatment. ( Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL, 1982) |
| "Baseline and mitomycin C (MMC)-induced sister chromatid exchanges (SCEs) in two human tumor cell lines (a colon tumor and a melanoma) and in a normal fibroblast cell line were analyzed and compared." | 3.66 | Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line. ( Au, WW; Hsu, TC; Li, S; Schmoyer, RL, 1982) |
| "The response rate and time to disease progression were the primary endpoints, with overall survival as the secondary endpoint." | 2.71 | Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study. ( Amicucci, G; Deraco, M; Di Filippo, F; Fiorentini, G; Guadagni, S; Miotto, D; Patuzzo, R; Pilati, PL; Rossi, CR; Santinami, M; Valenti, M, 2003) |
| "We successfully treated nodular melanoma and diffuse PAM in a young black woman using a combination of excision with cryotherapy and topical mitomycin C, suggesting that these lesions are amenable to the same types of therapy previously described for white patients." | 2.43 | Conjunctival melanoma arising from diffuse primary acquired melanosis in a young black woman. ( Colby, KA; Nagel, DS, 2005) |
| "Five-year survival rates were 57% for squamous cell carcinoma, 63% for adenocarcinoma, and 33% for melanoma." | 2.40 | Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes. ( Klas, JV; Madoff, RD; Rothenberger, DA; Wong, WD, 1999) |
| "Conjunctival melanoma is extremely rare in children and has low rates of resolution." | 1.72 | Fluorescent in situ hybridization (FISH): A useful diagnostic tool for childhood conjunctival melanoma. ( María Moral, R; María Peiró, A; Monteagudo, C; Moreno, L; Muriel, J, 2022) |
| " If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications." | 1.31 | [The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001) |
| "We observed euploid DNA-polyploidy and cytomorphological changes in all patients (19/19)." | 1.31 | Topical mitomycin C and radiation induce conjunctival DNA-polyploidy. ( Böcking, A; Cartsburg, O; Hillenkamp, J; Kallen, C; Pomjanski, N; Sundmacher, R, 2001) |
| "DNA cytometry showed nonaneuploidy in all of these." | 1.30 | Cytologic and DNA cytometric diagnosis and therapy monitoring of squamous cell carcinoma in situ and malignant melanoma of the cornea and conjunctiva. ( Böcking, A; Kersten, A; Krallmann, R; Motherby, H; Nadjari, B; Ross, B; Sundmacher, R, 1999) |
| " On the other hand, results from isolated limb perfusion for satellitosis and in-transit metastasis suggest distinct dose-response correlations with tumoricidal properties of appropriate antineoplastic agents." | 1.28 | [Systemically administered regional tumor therapy. Regional hemi-body chemotherapy of metastatic malignant melanoma--an experimental therapy concept]. ( Aigner, KR; Link, KH; Müller, H; Voigt, H; Walther, H, 1989) |
| "Mitomycin C (MMC) has been evaluated in combination with several antitumor agents." | 1.27 | Mitomycin C combination therapy against murine tumor systems. Effectiveness with cyclophosphamide and methotrexate. ( Mabel, JA; Wodinsky, I, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (27.17) | 18.7374 |
| 1990's | 14 (15.22) | 18.2507 |
| 2000's | 31 (33.70) | 29.6817 |
| 2010's | 17 (18.48) | 24.3611 |
| 2020's | 5 (5.43) | 2.80 |
| Authors | Studies |
|---|---|
| Sengupta, SK | 2 |
| Kelly, C | 1 |
| Sehgal, RK | 2 |
| Rosenbaum, DP | 1 |
| Almassian, B | 1 |
| Blondin, J | 1 |
| Iyengar, BS | 2 |
| Sami, SM | 1 |
| Remers, WA | 2 |
| Bradner, WT | 3 |
| Schurig, JE | 2 |
| Lin, HJ | 1 |
| Cheng, L | 1 |
| Lee, JJ | 1 |
| Stephenson, KAJ | 1 |
| Forristal, MT | 1 |
| McElnea, EM | 1 |
| Shan, S | 1 |
| Jia, S | 1 |
| Lawson, T | 1 |
| Yan, L | 1 |
| Lin, M | 1 |
| Liu, Y | 1 |
| Mazzini, C | 1 |
| Pieretti, G | 1 |
| Vicini, G | 1 |
| Nicolosi, C | 1 |
| Virgili, G | 1 |
| Giansanti, F | 1 |
| Westekemper, H | 2 |
| Manthey, A | 1 |
| Bechrakis, N | 1 |
| Soto, H | 1 |
| Bowen, RC | 1 |
| Raval, V | 1 |
| Yeaney, G | 1 |
| Singh, A | 1 |
| María Moral, R | 1 |
| Monteagudo, C | 1 |
| Muriel, J | 1 |
| Moreno, L | 1 |
| María Peiró, A | 1 |
| Chaparro Tapias, TA | 1 |
| Díaz Díaz, AL | 1 |
| Secondi, R | 1 |
| Coy Villamil, H | 1 |
| Sánchez España, JC | 1 |
| Moiseenko, AV | 1 |
| Polikarpov, AA | 1 |
| Tarazov, PG | 1 |
| Korovina, YV | 1 |
| Rozengauz, EV | 1 |
| Shelkoplyas, EN | 1 |
| Granov, DA | 1 |
| Farshid, P | 1 |
| Darvishi, A | 1 |
| Naguib, N | 1 |
| Bazrafshan, B | 1 |
| Paul, J | 1 |
| Mbalisike, E | 1 |
| Vogl, TJ | 1 |
| Salazar Méndez, R | 1 |
| Baamonde Arbaiza, B | 1 |
| de la Roz Martín, P | 1 |
| Parra Rodríguez, T | 1 |
| Treloar, KK | 1 |
| Simpson, MJ | 1 |
| Haridas, P | 1 |
| Manton, KJ | 1 |
| Leavesley, DI | 1 |
| McElwain, DL | 1 |
| Baker, RE | 1 |
| Damato, B | 1 |
| Coupland, SE | 1 |
| Schallenberg, M | 1 |
| Niederdräing, N | 1 |
| Steuhl, KP | 2 |
| Meller, D | 1 |
| Echternach, M | 1 |
| Arndt, S | 1 |
| Mattern, D | 1 |
| Maier, W | 1 |
| Richter, B | 1 |
| Cunneen, TS | 1 |
| Conway, RM | 2 |
| Madigan, MC | 1 |
| Dayani, PN | 1 |
| Gould, JE | 1 |
| Brown, DB | 1 |
| Sharma, KV | 1 |
| Linette, GP | 1 |
| Harbour, JW | 1 |
| Liang, SY | 1 |
| Lee, GA | 1 |
| Whitehead, K | 1 |
| Zimmermann, P | 1 |
| Dietrich, T | 1 |
| Bock, F | 1 |
| Horn, FK | 1 |
| Hofmann-Rummelt, C | 1 |
| Kruse, FE | 1 |
| Cursiefen, C | 1 |
| Rudkin, AK | 1 |
| Muecke, JS | 1 |
| Jiang, YY | 2 |
| Wang, HJ | 2 |
| Wang, J | 1 |
| Tashiro, S | 2 |
| Onodera, S | 2 |
| Ikejima, T | 2 |
| Grover, S | 1 |
| Jacobs, DS | 1 |
| Colby, KA | 3 |
| Hoyer, A | 1 |
| Raiskup, F | 1 |
| Pillunat, E | 1 |
| Shildkrot, Y | 2 |
| Wilson, MW | 2 |
| Hoh, L | 2 |
| Gravells, P | 2 |
| Canovas, D | 2 |
| Ul-Hassan, A | 1 |
| Rennie, IG | 2 |
| Bryant, H | 1 |
| Sisley, K | 2 |
| Freistuehler, M | 1 |
| Anastassiou, G | 1 |
| Nareyeck, G | 1 |
| Zeschnigk, M | 1 |
| Bornfeld, N | 1 |
| Scheulen, ME | 1 |
| Hilger, RA | 1 |
| Yang, R | 1 |
| Huang, H | 1 |
| Wu, D | 1 |
| Bryant, HE | 1 |
| Ditta, LC | 1 |
| Yamashita, T | 1 |
| Uramoto, H | 1 |
| Nagaie, T | 1 |
| Khan, MA | 1 |
| Lanitis, S | 1 |
| Desai, AP | 1 |
| Rosin, RD | 1 |
| Jain, S | 1 |
| Chandravanshi, SL | 1 |
| Rathore, MK | 1 |
| Goyal, P | 1 |
| Jain, SC | 1 |
| Masson, C | 1 |
| Menaa, F | 1 |
| Pinon-Lataillade, G | 1 |
| Frobert, Y | 1 |
| Chevillard, S | 1 |
| Radicella, JP | 1 |
| Sarasin, A | 1 |
| Angulo, JF | 1 |
| Guadagni, S | 1 |
| Santinami, M | 1 |
| Patuzzo, R | 1 |
| Pilati, PL | 1 |
| Miotto, D | 1 |
| Deraco, M | 1 |
| Rossi, CR | 1 |
| Fiorentini, G | 1 |
| Di Filippo, F | 1 |
| Valenti, M | 1 |
| Amicucci, G | 1 |
| Sacu, S | 1 |
| Ségur-Eltz, N | 1 |
| Horvat, R | 1 |
| Lukas, JR | 1 |
| Zehetmayer, M | 1 |
| Konovalova, NP | 1 |
| THIELE, EH | 1 |
| ARISON, RN | 1 |
| BOXER, GE | 1 |
| ISHIBASHI, Y | 1 |
| SULLIVAN, RD | 1 |
| ZUREK, WZ | 1 |
| Groh, MJ | 1 |
| Holbach, LM | 1 |
| Kühnel, B | 1 |
| Naumann, GO | 1 |
| Han, J | 1 |
| Colditz, GA | 1 |
| Samson, LD | 1 |
| Hunter, DJ | 1 |
| Nagel, DS | 1 |
| Kurli, M | 1 |
| Finger, PT | 4 |
| Becerra, EM | 1 |
| Blanco, G | 1 |
| Saornil, MA | 1 |
| del C Méndez, M | 1 |
| Bianciotto, CG | 1 |
| Passagne, I | 1 |
| Evrard, A | 1 |
| Depeille, P | 1 |
| Cuq, P | 1 |
| Cupissol, D | 1 |
| Vian, L | 1 |
| Krohn, J | 1 |
| Monge, OR | 1 |
| Abraham, LM | 1 |
| Selva, D | 1 |
| Casson, R | 1 |
| Leibovitch, I | 1 |
| Khong, JJ | 1 |
| Muecke, J | 1 |
| Vogl, T | 1 |
| Eichler, K | 1 |
| Zangos, S | 1 |
| Herzog, C | 1 |
| Hammerstingl, R | 1 |
| Balzer, J | 1 |
| Gholami, A | 1 |
| Sugiura, M | 1 |
| Mihm, MC | 1 |
| Zembowicz, A | 1 |
| Anandajeya, WV | 1 |
| Corrêa, ZM | 1 |
| Augsburger, JJ | 1 |
| Hashida, M | 1 |
| Kato, A | 1 |
| Kojima, T | 1 |
| Muranishi, S | 1 |
| Sezaki, H | 1 |
| Tanigawa, N | 1 |
| Satomura, K | 1 |
| Hikasa, Y | 1 |
| Imamishi, J | 1 |
| Tanaka, A | 1 |
| Mabel, JA | 1 |
| Wodinsky, I | 1 |
| Ghelelovitch, S | 1 |
| Ozaki, A | 1 |
| Saijo, N | 1 |
| Beppu, Y | 1 |
| Takahashi, K | 1 |
| Shimizu, E | 1 |
| Kimata, M | 1 |
| Hoshi, A | 1 |
| Ninomiya, K | 1 |
| Sekido, S | 1 |
| Araki, T | 1 |
| Pedersen, JE | 1 |
| Barron, G | 1 |
| Nosoh, Y | 1 |
| Yoshinaka, K | 1 |
| Yamaguchi, M | 1 |
| Tani, T | 1 |
| Toge, T | 1 |
| Niimoto, M | 1 |
| Hattori, T | 1 |
| Rose, WC | 1 |
| Schlein, A | 1 |
| Huftalen, JB | 1 |
| Carter, WH | 1 |
| Wampler, GL | 1 |
| Stablein, DM | 1 |
| Campbell, ED | 1 |
| Li, S | 1 |
| Au, WW | 1 |
| Schmoyer, RL | 1 |
| Hsu, TC | 1 |
| Satoh, S | 1 |
| Suzuki, A | 1 |
| Okamura, H | 1 |
| Nishimura, T | 1 |
| Turk, PS | 1 |
| Belliveau, JF | 1 |
| Darnowski, JW | 1 |
| Weinberg, MC | 1 |
| Leenen, L | 1 |
| Wanebo, HJ | 1 |
| Kumazawa, H | 1 |
| Hess, M | 1 |
| Koldovsky, P | 1 |
| Milner, MS | 1 |
| McCormick, SA | 2 |
| Logan, TF | 1 |
| Gooding, W | 1 |
| Kirkwood, JM | 1 |
| Shadduck, RK | 1 |
| Gutman, M | 1 |
| Abu-Abid, S | 1 |
| Sorkine, P | 1 |
| Inbar, M | 1 |
| Lev, D | 1 |
| Chen, Z | 1 |
| Oron, D | 1 |
| Chaitchik, S | 1 |
| Klausner, JM | 1 |
| Saitoh, S | 1 |
| Kurisaka, M | 1 |
| Mori, K | 1 |
| Maeda, N | 1 |
| Fujimoto, S | 1 |
| Kent, CJ | 1 |
| Jakobiec, FA | 1 |
| Czechonska, G | 1 |
| Liarikos, S | 1 |
| Werschnik, C | 1 |
| Lommatzsch, PK | 1 |
| Klas, JV | 1 |
| Rothenberger, DA | 1 |
| Wong, WD | 1 |
| Madoff, RD | 1 |
| Benbow, U | 1 |
| Maitra, R | 1 |
| Hamilton, JW | 1 |
| Brinckerhoff, CE | 1 |
| Nadjari, B | 1 |
| Kersten, A | 1 |
| Ross, B | 1 |
| Motherby, H | 1 |
| Krallmann, R | 1 |
| Sundmacher, R | 2 |
| Böcking, A | 2 |
| Demirci, H | 1 |
| Paridaens, D | 1 |
| Beekhuis, H | 1 |
| van Den Bosch, W | 1 |
| Remeyer, L | 1 |
| Melles, G | 1 |
| Shields, CL | 1 |
| Shields, JA | 1 |
| Armstrong, T | 1 |
| Kemp, EG | 1 |
| Harnett, AN | 1 |
| Chatterjee, S | 1 |
| Schmidt, M | 1 |
| Maier, M | 1 |
| Schmidt, T | 1 |
| Klaehsen, D | 1 |
| Merté, RL | 1 |
| Cartsburg, O | 1 |
| Kallen, C | 1 |
| Hillenkamp, J | 1 |
| Pomjanski, N | 1 |
| Rümmelein, B | 1 |
| Drieschner, O | 1 |
| Ehlert, U | 1 |
| Weichenthal, M | 1 |
| Breitbart, EW | 1 |
| Rüdiger, HW | 1 |
| Giacomoni, D | 1 |
| Ben-Efraim, S | 1 |
| Najmabadi, F | 1 |
| Dray, S | 1 |
| Dillman, RO | 1 |
| Johnson, DE | 1 |
| Ogden, J | 1 |
| Beidler, D | 1 |
| Voigt, H | 2 |
| Aigner, KR | 1 |
| Link, KH | 1 |
| Walther, H | 1 |
| Müller, H | 1 |
| Hoon, DS | 1 |
| Bowker, RJ | 1 |
| Cochran, AJ | 1 |
| Desablens, B | 1 |
| Fievet, P | 1 |
| Pruna, A | 1 |
| Claisse, JF | 1 |
| Westeel, PF | 1 |
| Tolani, M | 1 |
| Fournier, A | 1 |
| Fishbein, PL | 1 |
| Kohn, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Observational Study on Isolated Limb Perfusion of Melphalan in Treating Patients With Metastasis or Recidivism of Limb Melanoma or Sarcoma That Are Not Operable[NCT01920516] | 40 participants (Anticipated) | Observational | 2013-07-31 | Recruiting | |||
| A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma (SISCCA) of the Anal Canal and Perianus in HIV-Infected Persons[NCT02437851] | Phase 2 | 16 participants (Actual) | Interventional | 2015-04-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for mitomycin and Melanoma
| Article | Year |
|---|---|
[Diagnosis and Therapy of Benign and Malignant Tumors of the Conjunctiva].
Topics: Adult; Child; Conjunctiva; Conjunctival Neoplasms; Humans; Melanoma; Mitomycin; Neoplasm Recurrence, | 2020 |
[Topical Mitomycin C as a therapy of conjunctival tumours].
Topics: Administration, Topical; Antibiotics, Antineoplastic; Carcinoma in Situ; Carcinoma, Squamous Cell; C | 2008 |
Conjunctival melanoma: pitfalls and dilemmas in management.
Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Cryotherapy; Humans; Lymphatic Metastasis; Mela | 2010 |
Conjunctival melanoma arising from diffuse primary acquired melanosis in a young black woman.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Black People; Combined Modality Therapy | 2005 |
Mitomycin: clinical applications in ophthalmic practice.
Topics: Antibiotics, Antineoplastic; Cicatrix; Conjunctival Neoplasms; Glaucoma; Humans; Melanoma; Mitomycin | 2006 |
Adjuvant therapy in malignant melanoma.
Topics: Adjuvants, Immunologic; Antibiotics, Antineoplastic; Combined Modality Therapy; Eye Neoplasms; Human | 1997 |
Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus | 1999 |
8 trials available for mitomycin and Melanoma
| Article | Year |
|---|---|
Repetitive chemoembolization of hypovascular liver metastases from the most common primary sites.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Chemoembolization, Therapeutic; Colorect | 2013 |
Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio | 2003 |
[Management of conjunctival malignant melanoma associated with primary acquired melanosis (PAM) using 0.02% mitomycin C eyedrops].
Topics: Administration, Topical; Antibiotics, Antineoplastic; Conjunctival Neoplasms; Female; Humans; Male; | 2003 |
Preliminary experience with transarterial chemoembolization (TACE) in liver metastases of uveal malignant melanoma: local tumor control and survival.
Topics: Adult; Aged; Chemoembolization, Therapeutic; Female; Follow-Up Studies; Humans; Injections, Intra-Ar | 2007 |
Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients.
Topics: Colonic Neoplasms; Fibroma; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Sti | 1996 |
Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma | 1996 |
Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Conjuncti | 1998 |
Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Atrophy; Chemotherapy, Adjuvant; | 2000 |
77 other studies available for mitomycin and Melanoma
| Article | Year |
|---|---|
"Reverse" and "symmetrical" analogues of actinomycin D: metabolic activation and in vitro and in vivo tumor growth inhibitory activities.
Topics: Animals; Biotransformation; Cattle; Chemical Phenomena; Chemistry, Physical; Dactinomycin; DNA; DNA, | 1985 |
Enantiomers of 7-(2,3-epoxypropoxy)actinomycin D as dual-action DNA-acting antitumor agents.
Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dactinomycin | 1988 |
Mitomycin C and porfiromycin analogues with substituted ethylamines at position 7.
Topics: Animals; Ethylamines; Female; Leukemia L1210; Leukemia P388; Leukopenia; Melanoma; Mice; Mitomycins; | 1983 |
Development of new mitomycin C and porfiromycin analogues.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Leukemia, Experimental; Melanoma; | 1981 |
Insidious ocular surface lesion in an 81-year-old woman.
Topics: Aged, 80 and over; Eye Neoplasms; Female; Humans; Melanoma; Mitomycin; Orbit; Skin Neoplasms | 2022 |
The Use of TAT Peptide-Functionalized Graphene as a Highly Nuclear-Targeting Carrier System for Suppression of Choroidal Melanoma.
Topics: Antibiotics, Antineoplastic; Cell Line; Cell Line, Tumor; Cell Nucleus; Choroid Neoplasms; Drug Carr | 2019 |
Extensive conjunctival melanoma successfully treated with surgical resection and pre- and postoperative topical mitomycin C.
Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Humans; Male; Melanoma; Melanosis; Middle Aged; | 2021 |
Primary acquired melanosis/melanoma: utility of conjunctival map biopsy.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Conjunctival Neoplasms; Female; Humans; Melanoma; Melanoma, | 2022 |
Fluorescent in situ hybridization (FISH): A useful diagnostic tool for childhood conjunctival melanoma.
Topics: Child; Conjunctival Neoplasms; Humans; In Situ Hybridization, Fluorescence; Melanoma; Mitomycin; Rar | 2022 |
Resolution of conjunctival melanoma with topical interferon alpha 2b in a patient with mitomycin C intolerance.
Topics: Administration, Ophthalmic; Aged; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Conjunctival Neo | 2018 |
[Regional chemotherapy in treatment of patients with unresectable liver metastases of uveal melanoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemoembolization, Therape | 2016 |
[Treatment of conjunctival melanoma].
Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Chemotherapy, Adjuvant; Combined Modal | 2014 |
Multiple types of data are required to identify the mechanisms influencing the spatial expansion of melanoma cell colonies.
Topics: Cell Adhesion; Cell Count; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Size; Humans; K | 2013 |
An audit of conjunctival melanoma treatment in Liverpool.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Brachytherapy; | 2009 |
Recurrent laryngeal metastasis of a malignant melanoma: surgical therapy with the first application of mitomycin C.
Topics: Aged; Antigens, Neoplasm; Antineoplastic Agents; Combined Modality Therapy; Dysphonia; Female; Human | 2009 |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells.
Topics: Apoptosis; Butyrates; Cell Cycle; Cell Proliferation; Cell Survival; Conjunctival Neoplasms; Connect | 2009 |
Hepatic metastasis from uveal melanoma: angiographic pattern predictive of survival after hepatic arterial chemoembolization.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Cisplat | 2009 |
Histopathology of a functioning mitomycin-C trabeculectomy.
Topics: Anterior Eye Segment; Blister; Eye Enucleation; Glaucoma; Humans; Iris Neoplasms; Male; Melanoma; Mi | 2009 |
Tumour-associated lymphangiogenesis in conjunctival malignant melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctival Neoplasms; Female; Humans; | 2009 |
Topical mitomycin following cryotherapy for treatment of recurrent ocular surface melanoma.
Topics: Administration, Topical; Aged, 80 and over; Antibiotics, Antineoplastic; Combined Modality Therapy; | 2009 |
The protective effect of silibinin against mitomycin C-induced intrinsic apoptosis in human melanoma A375-S2 cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Death | 2009 |
Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma.
Topics: Aged; Alkylating Agents; Artificial Organs; Conjunctival Neoplasms; Corneal Diseases; Epithelium, Co | 2010 |
[Mitomycin C in diffuse multilocal malignant conjunctival melanoma].
Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Humans; Melanoma; Mitomycin; Treatment Outcome | 2010 |
Atypically low spontaneous sister chromatid exchange formation in uveal melanoma.
Topics: Apoptosis; Cell Growth Processes; Cell Line, Tumor; Female; Histones; Humans; In Situ Hybridization, | 2011 |
Chemosensitivity of conjunctival melanoma cell lines to chemotherapeutic agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Conjunctival Neoplasms; Humans; Melanoma; Mitomycin; Nitros | 2011 |
Mechanism of autophagy induction and role of autophagy in antagonizing mitomycin C-induced cell apoptosis in silibinin treated human melanoma A375-S2 cells.
Topics: Adenine; Apoptosis; Autophagy; Cell Line, Tumor; Down-Regulation; Humans; Melanoma; Mitomycin; NF-ka | 2011 |
Resistance of uveal melanoma to the interstrand cross-linking agent mitomycin C is associated with reduced expression of CYP450R.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cross-Linking Reagents; DNA Damage; Drug Resistance, | 2011 |
Outcomes in 15 patients with conjunctival melanoma treated with adjuvant topical mitomycin C: complications and recurrences.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctival N | 2011 |
Long-term survivor of primary anorectal malignant melanoma by a multi-disciplinary approach.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fem | 2011 |
Therapeutic isolated limb perfusion (ILP) in the management of patients with advanced or recurrent limb melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Humans; Lo | 2012 |
Huge malignant melanoma of caruncle with extensive involvement of conjunctiva.
Topics: Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctival Neoplasms; Cryotherapy; Humans; | 2012 |
Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication.
Topics: Activating Transcription Factor 2; Cyclic AMP Response Element-Binding Protein; DNA Repair; DNA Repl | 2003 |
Intumescent cataract after topical mitomycin-C for conjunctival malignant melanoma.
Topics: Administration, Topical; Antibiotics, Antineoplastic; Cataract; Cataract Extraction; Conjunctival Ne | 2003 |
Ultralow doses of various drugs in chemotherapy of experimental tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Resp | 2003 |
ONCOLYSIS BY CLOSTRIDIA. III. EFFECTS OF CLOSTRIDIA AND CHEMOTHERAPEUTIC AGENTS ON RODENT TUMORS.
Topics: Adenocarcinoma; Animals; Antimetabolites; Antineoplastic Agents; Aziridines; Bacteriological Techniq | 1964 |
CANCER CHEMOTHERAPY (MITOMYCIN-C) FOLLOWED BY BONE MARROW TRANSPLANTATION.
Topics: Bone Marrow Transplantation; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Bronchogenic; Choriocarci | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
Polymorphisms in DNA double-strand break repair genes and skin cancer risk.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Case-Control Studies; Cell Survival; DNA Dam | 2004 |
Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: 12 years' experience.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Conjunctival N | 2005 |
Hughes technique, amniotic membrane allograft, and topical chemotherapy in conjunctival melanoma with eyelid involvement.
Topics: Administration, Topical; Amnion; Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctiva | 2005 |
O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Dacarbazine; Dose-Re | 2006 |
[Conjunctival primary acquired melanosis].
Topics: Aged; Antibiotics, Antineoplastic; Conjunctival Diseases; Conjunctival Neoplasms; Cryotherapy; Diagn | 2005 |
Complications of mitomycin C therapy in 100 eyes with ocular surface neoplasia.
Topics: Adenocarcinoma, Sebaceous; Antibiotics, Antineoplastic; Carcinoma in Situ; Carcinoma, Squamous Cell; | 2006 |
Low-risk and high-risk histologic features in conjunctival primary acquired melanosis with atypia: Clinicopathologic analysis of 29 cases.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Cell Nucleolus; Cell Nucleus; Chemother | 2007 |
Primary acquired melanosis with atypia treated with mitomycin C.
Topics: Alkylating Agents; Conjunctival Diseases; Conjunctival Neoplasms; Cryosurgery; Humans; Male; Melanom | 2009 |
Antitumor activity of mitomycin C-dextran conjugate against various murine tumors.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dextrans; Female; Injections, Intravenous; | 1981 |
[Experimental research to clinical application of interferons].
Topics: Animals; Bleomycin; Cytarabine; Drug Therapy, Combination; Humans; Interferon Inducers; Interferon T | 1984 |
Mitomycin C combination therapy against murine tumor systems. Effectiveness with cyclophosphamide and methotrexate.
Topics: Animals; Antibiotics, Antineoplastic; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, C | 1983 |
Effect of the inhibition of nucleic acids and protein synthesis upon the development of melanotic tumors in Drosophila.
Topics: Animals; Cell Division; Chloramphenicol; Cycloheximide; Dactinomycin; Drosophila melanogaster; Ethid | 1983 |
[Analysis of the mechanism of cancer metastasis by using anticancer agents].
Topics: Animals; Antineoplastic Agents; Cell Division; Cisplatin; Killer Cells, Natural; Liver Neoplasms; Ma | 1984 |
[Effect of combination chemotherapy of nitrosourea MCNU with various anti-tumor agents].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Cell Line; Cyclophosphamid | 1984 |
Radiation and concurrent chemotherapy for the treatment of Lewis lung tumor and B16 melanoma tumor in C57/BL mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cesium Radioisotopes | 1984 |
[Increased cytotoxic effects of various anticancer drugs by alpha-interferon (HLBI) on human tumor xenografts in nude mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Syner | 1984 |
Antitumor activity and toxicity in animals of RR-150 (7-cysteaminomitosane), a new mitomycin derivative.
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistan | 1984 |
Drug activity and therapeutic synergism in cancer treatment.
Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration S | 1982 |
Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line.
Topics: Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Colonic Neoplasms; Crossing Over, Ge | 1982 |
[Case of malignant melanoma of the external genitalia responding satisfactorily to a combination of local injection of OK-432 and chemotherapy].
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Biological Products; Cyclophosphamide; Drug Administr | 1982 |
Isolated pelvic perfusion for unresectable cancer using a balloon occlusion technique.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcino | 1993 |
Morphologic analysis of three-dimensional tumors developed in fibrin matrix and agar culture system.
Topics: Adenocarcinoma; Agar; Animals; Cell Division; Cell Hypoxia; Colonic Neoplasms; Culture Techniques; E | 1993 |
Topical chemotherapy for conjunctival melanoma.
Topics: Administration, Topical; Conjunctiva; Conjunctival Neoplasms; Female; Humans; Melanoma; Middle Aged; | 1993 |
Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation.
Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Autoant | 1997 |
[Mitomycin C in treatment of conjunctival melanoma and primary acquired melanosis].
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Ther | 1998 |
Selective inhibition of collagenase-1, gelatinase A, and gelatinase B by chemotherapeutic agents.
Topics: Acetylcysteine; Antineoplastic Agents; Carboplatin; Cisplatin; Doxorubicin; Gelatinases; Humans; Mat | 1999 |
Cytologic and DNA cytometric diagnosis and therapy monitoring of squamous cell carcinoma in situ and malignant melanoma of the cornea and conjunctiva.
Topics: Aneuploidy; Antibiotics, Antineoplastic; Carcinoma in Situ; Carcinoma, Squamous Cell; Conjunctival N | 1999 |
Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia.
Topics: Administration, Topical; Aged; Amnion; Conjunctival Neoplasms; Corneal Transplantation; Female; Huma | 2001 |
Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy.
Topics: Adult; Amnion; Antibiotics, Antineoplastic; Combined Modality Therapy; Conjunctival Neoplasms; Corne | 2001 |
Preoperative topical and intraoperative local mitomycin C adjuvant therapy in the management of ocular surface neoplasias.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Carcinoma; Che | 2002 |
[The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years].
Topics: Administration, Topical; Aged; Biopsy; Cell Transformation, Neoplastic; Conjunctiva; Conjunctival Ne | 2001 |
Topical mitomycin C and radiation induce conjunctival DNA-polyploidy.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Combined Modality Therap | 2001 |
Increased mutagen sensitivity in human cultured fibroblasts with constitutively high micronucleus levels.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aphidicolin; Cells, Cultured; Fibroblasts; Human | 1992 |
Inhibitors of lymphocyte activation secreted by human melanoma cell lines.
Topics: Animals; Antineoplastic Agents; B-Lymphocytes; Female; Humans; Lipopolysaccharides; Lymphocyte Activ | 1990 |
Significance of antigen, drug, and tumor cell targets in the preclinical evaluation of doxorubicin, daunorubicin, methotrexate, and mitomycin-C monoclonal antibody immunoconjugates.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; Cytotoxicity, Immunologic; Daunorubi | 1989 |
[Systemically administered regional tumor therapy. Regional hemi-body chemotherapy of metastatic malignant melanoma--an experimental therapy concept].
Topics: Adult; Antineoplastic Agents; Catheters, Indwelling; Chemotherapy, Cancer, Regional Perfusion; Cispl | 1989 |
Suppressor cell activity in melanoma-draining lymph nodes.
Topics: Concanavalin A; Humans; Interleukin-2; Lymph Nodes; Melanoma; Mitomycin; Mitomycins; T-Lymphocytes; | 1987 |
Hemolytic-uremic syndrome after cancer chemotherapy without mitomycin C.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Hemolytic- | 1986 |
Synthesis and antineoplastic activity of 1a-formyl and 1a-thioformyl derivatives of mitomycin C and 2-methylaziridine.
Topics: Animals; Aziridines; Azirines; Formates; Leukemia P388; Melanoma; Mice; Mitomycin; Mitomycins; Struc | 1987 |
[Regional intra-arterial chemotherapy].
Topics: Cisplatin; Dacarbazine; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Melanoma; Mitomycin; Mit | 1988 |