mitomycin has been researched along with Mast-Cell Sarcoma in 7 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Mast-Cell Sarcoma: A unifocal malignant tumor that consists of atypical pathological MAST CELLS without systemic involvement. It causes local destructive growth in organs other than in skin or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we show that administration of low-dose melphalan (l -PAM, l -phenylalanine mustard) to mice bearing a large MOPC-315 plasmacytoma led to a rapid up-regulation of B7-1 (CD80), but not B7-2 (CD86), expression on the surface of MOPC-315 tumor cells." | 3.70 | Melphalan and other anticancer modalities up-regulate B7-1 gene expression in tumor cells. ( Bluestone, JA; Donepudi, M; Mokyr, MB; Sojka, DK, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marchand, M | 1 |
| Caspar, P | 1 |
| Boon, T | 1 |
| Schlager, SI | 1 |
| Ohanian, SH | 1 |
| Hoffmann, CC | 1 |
| Ehrke, MJ | 1 |
| Papp, G | 1 |
| Mihich, E | 1 |
| McKinnon, JG | 1 |
| Lalani, A | 1 |
| Sy, L | 1 |
| Bear, HD | 1 |
| Sojka, DK | 1 |
| Donepudi, M | 1 |
| Bluestone, JA | 1 |
| Mokyr, MB | 1 |
| Adachi, Y | 1 |
| Arii, S | 1 |
| Funaki, N | 1 |
| Higashitsuji, H | 1 |
| Fujita, S | 1 |
| Furutani, M | 1 |
| Mise, M | 1 |
| Zhang, W | 1 |
| Tobe, T | 1 |
| Ishizeki, S | 1 |
| Ohtsuka, M | 1 |
| Irinoda, K | 1 |
| Kukita, K | 1 |
| Nagaoka, K | 1 |
| Nakashima, T | 1 |
7 other studies available for mitomycin and Mast-Cell Sarcoma
| Article | Year |
|---|---|
Increased frequency of immunogenic variants obtained by repeated mutagen treatment of mouse mastocytoma P815.
Topics: Animals; Cell Division; Clone Cells; Epitopes; Genetic Variation; Lymphocyte Culture Test, Mixed; Ma | 1983 |
Role of membrane lipids in the immunological killing of tumor cells: I. Target cell lipids.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Membrane; Cytotoxicity, Immunologic; Doxorubic | 1983 |
Modification of mouse immune responses against allogeneic tumor by pretreatment of antigen with mitomycin C or X-irradiation.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; Female; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL | 1980 |
Generation of cytotoxic T lymphocytes from peripheral blood.
Topics: Animals; Cell Division; Female; Immunotherapy, Adoptive; Interleukin-2; Killer Cells, Lymphokine-Act | 1993 |
Melphalan and other anticancer modalities up-regulate B7-1 gene expression in tumor cells.
Topics: Animals; Antibiotics, Antineoplastic; Antigens, CD; Antineoplastic Agents, Alkylating; B7-1 Antigen; | 2000 |
Tumoricidal activity of Kupffer cells augmented by anticancer drugs.
Topics: Animals; Antigens, Surface; Doxorubicin; Fluorescent Antibody Technique; Kupffer Cells; Liver Neopla | 1992 |
Azinomycins A and B, new antitumor antibiotics. III. Antitumor activity.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Azabicyclo Compounds; Carcinoma, Ehrlic | 1987 |